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Effects of gadoxetic acid on liver elasticity measurement by using magnetic resonance elastography.

Abstract：

:The purpose of this study was to evaluate the effect of gadoxetic acid (Gd-EOB-DTPA) on measurements of liver stiffness by using magnetic resonance elastography (MRE). In this study, 104 consecutive patients (mean age, 67.7±9.4 years) underwent MRE using a 1.5-T MR scanner equipped with a cylindrical passive driver that was placed across the right chest wall for delivering vibrations. Axial gradient-echo images, which were automatically converted to elastograms that represented stiffness (kPa), were acquired using a continuous sinusoidal vibration of 60 Hz. Two raters independently placed a region of interest on the right lobe of the liver on the elastograms obtained before and after Gd-EOB-DTPA was administered. Liver stiffness was measured using these two elastograms and compared using a paired t test and correlation analysis. No significant difference was observed in liver stiffness before and after Gd-EOB-DTPA was administered (Rater 1, P=.1200; Rater 2, P=.3585). The correlation coefficients were 0.986 (Rater 1) and 0.984 (Rater 2), indicating excellent correlation between the stiffness values before and after Gd-EOB-DTPA was administered. Liver stiffness measured by MRE did not differ before and after Gd-EOB-DTPA was administered.

journal_name

Magn Reson Imaging

journal_title

Magnetic resonance imaging

authors

Motosugi U,Ichikawa T,Sou H,Sano K,Muhi A,Ehman RL,Araki T

doi

10.1016/j.mri.2011.08.005

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

128-32

issue

1

eissn

0730-725X

issn

1873-5894

pii

S0730-725X(11)00291-8

journal_volume

30

pub_type

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