Abstract：
BACKGROUND AND PURPOSE:Diffusion MRI characteristics have been used as biomarkers to guide prognosis in cerebral pathologies including brain metastases. The measurement of ADC is often described poorly in clinical and research studies with little detail given to the practical considerations of where to place ROIs, which post processing software package to use and how reproducible the resulting metrics will be. METHOD:We investigated a series of 12 patients with brain metastases and preoperative DWI. Three post processing platforms were used. ROI were placed over the tumour, peritumoural region and across the brain-tumour interface. These recordings were made by a neurosurgeon and a neuroradiologist. Inter-intra-observer variability was assessed using Bland-Altman analysis. An exploratory analysis of DWI with overall survival and tumour type was made. RESULTS:There was excellent correlation between the software packages used for all measures including assessing the whole tumour, selective regions with lowest ADC, the change of ADC across the brain-tumour interface and the relation of the tumour ADC to peritumoural regions and the normal white matter. There was no significant inter- or intra-observer variability for repeated readings. There were significant differences in the mean values obtained using different methodologies and different metrics had differing relationships to overall survival and primary tumour of origin. CONCLUSION:Diffusion weighted MRI metrics offer promise as potential non-invasive biomarkers in brain metastases and a variety of metrics have been shown to be reliably measured using differing platforms and observers.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
Zakaria R,Das K,Bhojak M,Radon M,Sluming V,Walker C,Jenkinson MDdoi
10.1016/j.mri.2013.12.010subject
Has Abstractpub_date
2014-04-01 00:00:00pages
291-6issue
3eissn
0730-725Xissn
1873-5894pii
S0730-725X(13)00416-5journal_volume
32pub_type
杂志文章abstract：:Pulsed field gradient (PFG) nuclear magnetic resonance (NMR) and microimaging experiments have been performed to study the diffusion of liquid alkanes into a variety of semicrystalline polyethylene (PE) samples. The results highlight the importance of the crystalline phase in controlling the diffusion process in terms...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(98)00032-0
更新日期：1998-06-01 00:00:00
abstract：:We present a novel approach to the nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) analysis of complex samples with nontrivial distribution of longitudinal relaxation rate R(1). Parametrically enabled relaxation filters with double and multiple inversion (PERFIDI) aim to separate signals arising ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2006.12.001
更新日期：2007-05-01 00:00:00
abstract：:With the recent development of integrated positron emission tomography-magnetic resonance imaging (PET-MRI) scanners, new possibilities for quantitative molecular imaging of cancer are realized. However, the practical advantages and potential clinical benefits of the ability to record PET and MRI data simultaneously m...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章,评审
doi：10.1016/j.mri.2012.06.001
更新日期：2012-11-01 00:00:00
abstract：:The hippocampal formation is a brain system that is implicated in learning and memory. The major input to the hippocampus arrives from the entorhinal cortex (EC) to the dentate gyrus (DG) through the perforant path. In the present work, we have investigated the functional properties of this connection by concomitantly...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2008.02.018
更新日期：2008-09-01 00:00:00
abstract：:We report a geographic area of prominent hypointensity in T2-weighted images vs. normal adjacent liver parenchyma in a patient with cholangiocarcinoma and lymphangitic metastasis of the liver after superparamagnetic iron oxide (SPIO) administration. The area showing this prominent signal drop showed Kupffer cell proli...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2007.10.012
更新日期：2008-05-01 00:00:00
abstract：:This summary attempts to provide forward-looking concepts regarding gadolinium related toxicity, as discussed in further detail in this issue. ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章,评审
doi：10.1016/j.mri.2016.09.002
更新日期：2016-12-01 00:00:00
abstract：:The discrimination of tumor boundaries from normal tissue, as well as the evaluation of tissue heterogeneity and tumor grading often continue to pose a challenge in MRI. Although yielding promising results in various fields of medical imaging, two- dimensional (2D) texture analysis in MRI has, until now, demonstrated ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(03)00201-7
更新日期：2003-11-01 00:00:00
abstract：UNLABELLED:The conventional diagnostic work-up of a patient suspected of having a vascular cause for stridor, or dysphagia, includes esophagography and bronchoscopy to delineate the abnormal structure without imaging the structure itself. Cine-angiography is regarded as the golden standard, but is not routinely perform...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(97)00245-2
更新日期：1998-01-01 00:00:00
abstract：:Functional magnetic resonance imaging (fMRI) of the cortex is a powerful tool for neuroscience research, and its use has been extended into the brainstem and spinal cord as well. However, there are significant technical challenges with extrapolating the developments that have been achieved in the cortex to their use i...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2008.01.038
更新日期：2008-07-01 00:00:00
abstract：:A new approach to solid-state imaging (SSI) is presented. The method relies on narrowing the resonance line using the Lee-Goldburg sequence. The technique is easy to implement in practice and may find widespread applications in materials science. ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(92)90409-s
更新日期：1992-01-01 00:00:00
abstract：:The purpose of this study was to analyze background parenchymal enhancement (BPE) in the contralateral normal breast of cancer patients during the course of neoadjuvant chemotherapy (NAC). Forty-five subjects were analyzed. Each patient had three MRIs, one baseline (B/L) and two follow-up (F/U) studies. The fibrogland...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2013.07.014
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:The diagnosis and management of mild traumatic brain injury (MTBI) continue to be subjects of debate, with varying opinions regarding the extent to which tissue-based impairments versus the impacts of other stressors cause ongoing disability. Detecting areas of the brain with abnormalities that can explain s...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2011.12.018
更新日期：2012-05-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(90)90253-x
更新日期：1990-01-01 00:00:00
abstract：PURPOSE:The detection of small parenchymal hepatic lesions identified by preoperative imaging remains a challenge for traditional pathologic methods in large specimens. We developed a magnetic resonance imaging (MRI) compatible localization device for imaging of surgical specimens aimed to improve identification and lo...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2016.11.021
更新日期：2017-04-01 00:00:00
abstract：:Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is often used to examine vascular function in malignant tumors and noninvasively monitor drug efficacy of antivascular therapies in clinical studies. However, complex numerical methods used to derive tumor physiological properties from DCE-MRI images can b...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2012.09.007
更新日期：2013-05-01 00:00:00
abstract：:Budd-Chiari syndrome (BCS) is a rare disorder caused by the obstruction of hepatic venous outflow, leading to sinusoidal congestion, ischemic injury to liver cells and portal hypertension. Long-term survival largely depends on whether hepatocellular carcinoma occurs. A recently available liver-specific contrast medium...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2010.10.013
更新日期：2011-05-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(96)00353-0
更新日期：1997-01-01 00:00:00
abstract：PURPOSE:To describe the patterns of bile distribution in the biliary tree, duodenum, jejunum, and stomach, and to determine the gallbladder ejection fraction (GBEF) by using functional magnetic resonance cholangiography (MRC) with gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid (Gd-EOB-DTPA) in healthy vol...
journal_title：Magnetic resonance imaging
pub_type： 临床试验,杂志文章
doi：10.1016/j.mri.2014.01.003
更新日期：2014-05-01 00:00:00
abstract：:A single injection of high-dose steroid (20 mg/kg) has been reported to induce necrotic lesions in the proximal metaphysis and diaphysis of the rabbit femur. In the rabbit osteonecrosis (ON) model induced by two-dose horse serum injections, contrast-enhanced magnetic resonance imaging (MRI) and T2*-weighted dynamic MR...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2008.07.001
更新日期：2009-02-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(01)00300-9
更新日期：2001-02-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(95)00018-c
更新日期：1995-01-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(89)90547-x
更新日期：1989-05-01 00:00:00
abstract：:The increasing size and number of data sets of large four dimensional (three spatial, one temporal) magnetic resonance (MR) cardiac images necessitates efficient segmentation algorithms. Analysis of phase-contrast MR images yields cardiac flow information which can be manipulated to produce accurate segmentations of t...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2014.08.019
更新日期：2015-01-01 00:00:00
abstract：:The aim of the study was to evaluate the relationship between the presence of right ventricular abnormalities detected by cardiac magnetic resonance (CMR) and QRS dispersion, the strongest independent predictor of sudden death in ARVC. A consecutive series of 40 patients from a single institution were recruited with a...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2012.06.005
更新日期：2012-12-01 00:00:00
abstract：:The value of NMR spectrometry as a way to understand the porosity and permeability of rocks is well documented. Other more esoteric parameters, such as restrictive diffusion, grain size distribution, and fluid viscosities have received less notice but are also available from the NMR measurements as laboratory studies ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(94)91537-7
更新日期：1994-01-01 00:00:00
abstract：:Parallel excitation using multiple transmit channels has emerged as an effective method to shorten multidimensional spatially selective radiofrequency (RF) pulses, which have a number of important applications, including B1 field inhomogeneity correction in high-field MRI. The specific absorption rate (SAR) is a prima...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2008.02.003
更新日期：2008-10-01 00:00:00
abstract：:Deep brain stimulation (DBS) is used increasingly in the field of movement disorders. The implanted electrodes create not only a prior risk to patient safety during MRI, but also a unique opportunity in the collection of functional MRI data conditioned by direct neural stimulation. We evaluated MRI-related heating for...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2005.02.007
更新日期：2005-05-01 00:00:00
abstract：:Phantoms for evaluation of nuclear magnetic resonance (NMR) imaging systems were made from water-based agarose gels, according to a standard procedure herein described. Copper sulfate (CuSO4) was included in the gels to further affect their proton relaxation characteristics. The proton relaxation rates of each batch o...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(86)91068-4
更新日期：1986-01-01 00:00:00
abstract：:Magnetic field gradients play a fundamental role in MR imaging and localized spectroscopy. The MRI experiment, in particular fast MRI, relies on precise gradient switching, which has become more demanding with the constantly growing number of fast imaging techniques. Here we present a simple MR method to measure the b...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2007.02.002
更新日期：2007-11-01 00:00:00
abstract：:The NMR relaxivities of Gd-EOB-DTPA and Gd-DTPA were determined in the kidney and liver of intact male Wistar rats immediately following sacrifice and in vitro in solutions and gels, at 1.5 T using a clinical MR scanner, T1 and T2 values of tissue samples were derived from spin-echo image sequences. Tissue gadolinium ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(95)02097-d
更新日期：1996-01-01 00:00:00
