Psychometric properties of the positive and negative syndrome scale (PANSS) in schizophrenia.


:We analyzed the psychometric properties of the Positive and Negative Syndrome Scale (PANSS) in a sample of 100 DSM-III-R schizophrenic patients. Our findings coincided with the results of Kay's group in the following points: (1) the PANSS scores were normally distributed; (2) the positive and negative scales showed good interrater reliability; (3) positive and negative syndromes are independent constructs; (4) the positive and negative scales held a high concurrent validity in relation to the Scale for the Assessment of Positive Symptoms and the Scale for the Assessment of Negative Symptoms; and (5) although positive and negative syndromes showed factorial validity, they were not sufficient to account for the whole of the schizophrenic symptoms. Unlike Kay's group, we found a modest internal consistency of the positive scale, indicating that it is composed of several independent components. The data suggest that the distinction between positive and negative symptoms is an oversimplification, and that schizophrenic symptoms can be better conceptualized as composed of, at least three dimensional syndromes: positive, disorganized, and negative.


Psychiatry Res


Psychiatry research


Peralta V,Cuesta MJ




Has Abstract


1994-07-01 00:00:00














  • A comparison of paroxetine versus paroxetine plus amisulpride in the treatment of dysthymic disorder: efficacy and psychosocial outcomes.

    abstract::Dysthymic disorder is a chronic depressive condition with considerable psychosocial impairment. Even if DD patients respond to various antidepressant medications, there has been little systematic study on antidepressant-refractory DD. Only a few trials have evaluated the effects of treatment on psychosocial functionin...

    journal_title:Psychiatry research

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Rocca P,Marchiaro L,Rasetti R,Rivoira E,Bogetto F

    更新日期:2002-10-10 00:00:00

  • Effects of recurrent major depressive disorder on behavior and cognitive function in female depressed patients.

    abstract::Little is known about the effects of recurring depressive episodes on cognition and behavior. The objective of the study was to compare cognitive function and depression-related behavior between healthy female subjects and female outpatients with early-onset DSM-IV recurrent major depressive disorder and to investigat...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Lampe IK,Sitskoorn MM,Heeren TJ

    更新日期:2004-02-15 00:00:00

  • Language disturbance and functioning in first episode psychosis.

    abstract::Language disturbance has a central role in the presentation of psychotic disorders however its relationship with functioning requires further clarification, particularly in first episode psychosis (FEP). Both language disturbance and functioning can be evaluated with clinician-rated and performance-based measures. We ...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Roche E,Segurado R,Renwick L,McClenaghan A,Sexton S,Frawley T,Chan CK,Bonar M,Clarke M

    更新日期:2016-01-30 00:00:00

  • Aggression as an independent entity even in psychosis - The role of cortisol.

    abstract::Aggression is a common entity in psychiatric disorders, particularly psychotic disorders. Glucocorticoid hypofunction has been linked to abnormal forms of aggressive behavior in various studies in a 'possibly causal' role. We hypothesise that aggression, even among those having psychosis is associated with glucocortic...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Das S,Sengupta S,Pathak K,Sah D,Mehta S,Avinash PR,Baruah A,Deuri SK,Sarmah A,Gogoi V,Kalita KN,Hazarika J

    更新日期:2018-01-01 00:00:00

  • Standardization of Brief Inventory of Social Support Exchange Network (BISSEN) in Japan.

    abstract::This study describes the Brief Inventory of Social Support Exchange Network (BISSEN) as a standardized brief inventory measuring various aspects of social support. We confirmed the reliability and validity for function and direction of support and standardized the BISSEN. For Sample 1, a stratified random sampling met...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Aiba M,Tachikawa H,Fukuoka Y,Lebowitz A,Shiratori Y,Doi N,Matsui Y

    更新日期:2017-07-01 00:00:00

  • Associations of beta-endorphin with HVA and MHPG in the plasma of prepubertal boys: effects of familial drug abuse and antisocial personality disorder liability.

    abstract::It is well-established that the secretion of the opioid neuropeptide beta-endorphin is perturbed by the administration of various drugs of abuse. Several investigators have speculated that variations in beta-endorphin secretory regulation may precede the development of a substance use disorder, and thus be a component...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Moss HB,Yao JK

    更新日期:1996-06-01 00:00:00

  • The impact of perceived stigma on psychiatric care and outcomes for correctional mental health patients.

    abstract::The purpose of this study was to examine factors related to the delivery and effectiveness of psychiatric care prior to and following prison release. Particular attention was placed on patients' self-reported needs, psychiatric medication adherence, and perceived stigma related to mental health treatment, and how thes...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Farabee D,Hall E,Zaheer A,Joshi V

    更新日期:2019-06-01 00:00:00

  • Prevalence of work-related common psychiatric disorders in primary care: The French Héraclès study.

    abstract::General practitioners (GP), on the frontline for individuals with mental health problems, often deal with work-related common psychiatric disorders. We aimed to determine the prevalence of work-related common psychiatric disorders in general practice and associated patients' and GPs' characteristics. HERACLES, a cross...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Rivière M,Plancke L,Leroyer A,Blanchon T,Prazuck T,Prouvost H,Sobczak B,De Pauw C,Ferreira Carreira L,Toullic Y,Lerouge P,Melchior M,Younès N

    更新日期:2018-01-01 00:00:00

  • Increased risk of gout among patients with bipolar disorder: a nationwide population-based study.

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    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Chung KH,Huang CC,Lin HC

    更新日期:2010-12-30 00:00:00

  • Relationship of object loss during development to hypothalamic-pituitary-adrenal axis function during major affective illness later in life.

    abstract::Although many studies have attempted to determine whether early object loss influences the risk of developing major affective illness in adulthood, there are few empirical data relating early loss to subsequent hypothalamic-pituitary-adrenal (HPA) axis dysfunction in adulthood. Forty-five psychiatric inpatients admitt...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Petitto JM,Quade D,Evans DL

    更新日期:1992-12-01 00:00:00

  • Psychosocial predictors of psychological, neurochemical and immunological symptoms of acute stress among breast cancer patients.

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    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Gerits P,De Brabander B

    更新日期:1999-01-18 00:00:00

  • Changes in serum miRNA-let-7 level in children with attention deficit hyperactivity disorder treated by repetitive transcranial magnetic stimulation or atomoxetine: An exploratory trial.

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    journal_title:Psychiatry research

    pub_type: 杂志文章,随机对照试验


    authors: Cao P,Wang L,Cheng Q,Sun X,Kang Q,Dai L,Zhou X,Song Z

    更新日期:2019-04-01 00:00:00

  • Quality of life of 'normal' controls: association with lifetime history of mental illness.

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    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Schechter D,Endicott J,Nee J

    更新日期:2007-07-30 00:00:00

  • Inhibition and response to error in remitted major depression.

    abstract::Depression is a common illness which tends to have a relapsing progression. Revealing vulnerability factors is an important step towards improved treatment and prevention. Previous studies of individuals in remission indicate that inhibitory control is more strongly impaired than other cognitive functions. Studies hav...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Aker M,Bø R,Harmer C,Stiles TC,Landrø NI

    更新日期:2016-01-30 00:00:00

  • Cognitive performance in schizophrenia: relationship to regional brain volumes and psychiatric symptoms.

    abstract::In an all-male sample of schizophrenic patients stabilized by medication (n=62) and normal controls (n=27), we obtained neuropsychological test data and high-resolution whole brain magnetic resonance scans, as well as detailed psychiatric rating scales on a subset of the patients (n=47). Schizophrenic patients had sig...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Sanfilipo M,Lafargue T,Rusinek H,Arena L,Loneragan C,Lautin A,Rotrosen J,Wolkin A

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  • Care pathways, engagement and outcomes associated with a recovery-oriented intermediate stay mental health program.

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    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Sly KA,Lewin TJ,Frost BG,Tirupati S,Turrell M,Conrad AM

    更新日期:2020-02-20 00:00:00

  • Cortical thickness differences in the prefrontal cortex in children and adolescents with ADHD in relation to dopamine transporter (DAT1) genotype.

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    pub_type: 杂志文章


    authors: Fernández-Jaén A,López-Martín S,Albert J,Fernández-Mayoralas DM,Fernández-Perrone AL,de La Peña MJ,Calleja-Pérez B,Rodríguez MR,López-Arribas S,Muñoz-Jareño N

    更新日期:2015-09-30 00:00:00

  • Neuroendocrine abnormalities associated with untreated first episode patients of major depressive disorder with comorbid obstructive sleep apnea.

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    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Zhang H,Yuan J,Zhang Y,Wei Y,Xu L,Zhou F,Fan X,Kang C,Yang J

    更新日期:2020-09-01 00:00:00

  • Preliminary validation of a set of content analysis scales applicable to verbal samples for measuring the magnitude of psychological states in children.

    abstract::Scores on 17 psychological dimensions of the Gottschalk-Gleser content analysis scales were obtained from 5-minute speech samples of 37 white children hospitalized on the psychiatric service of a general hospital. These content analysis scores were compared to identical scores obtained from a normative sample of 109 w...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Gottschalk LA,Uliana RL,Hoigaard JC

    更新日期:1979-07-01 00:00:00

  • Reinforcement learning deficits in people with schizophrenia persist after extended trials.

    abstract::Previous research suggests that people with schizophrenia have difficulty learning from positive feedback and when learning needs to occur rapidly. However, they seem to have relatively intact learning from negative feedback when learning occurs gradually. Participants are typically given a limited amount of acquisiti...

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    pub_type: 杂志文章


    authors: Cicero DC,Martin EA,Becker TM,Kerns JG

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  • Direct assessment of improvement in winter depression with a visual analogue scale: high reliability and validity.

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    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Lingjaerde O,Føreland AR

    更新日期:1998-12-14 00:00:00

  • GSK-3 parameters in lymphocytes of schizophrenic patients.

    abstract::Glycogen synthase kinase-3 (GSK-3) is a highly conserved serine/threonine protein kinase that is involved in the signal transduction cascades of multiple cellular processes. GSK-3 has two isoforms, designated alpha and beta. GSK-3beta protein levels and GSK-3 enzyme activity have been reported to be reduced by over 40...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Nadri C,Kozlovsky N,Agam G,Bersudsky Y

    更新日期:2002-09-15 00:00:00

  • The longitudinal course of cognitive insight and mood in bipolar disorder.

    abstract::Cognitive insight or the ability to be self-reflective and to retain from being over-confident in own beliefs is an upcoming topic in research regarding psychiatric disorders. In bipolar disorder investigations are scarce and an important lacuna is the unexamined longitudinal relationship between cognitive insight and...

    journal_title:Psychiatry research

    pub_type: 杂志文章,多中心研究


    authors: Van Camp L,van den Ameele S,Sabbe BGC,Oldenburg JFE

    更新日期:2018-11-01 00:00:00

  • Preliminary investigation of the impulsive and neuroanatomical characteristics of compulsive sexual behavior.

    abstract::In recent years, there has been increased interest in a clinical syndrome characterized by excessive sexual thoughts, sexual urges, and/or sexual behaviors that has many aspects in common with impulse control disorders. This study provides a preliminary examination of the impulsive aspects of this syndrome, compulsive...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Miner MH,Raymond N,Mueller BA,Lloyd M,Lim KO

    更新日期:2009-11-30 00:00:00

  • The psychometric validation of the Sheehan Disability Scale (SDS) in patients with bipolar disorder.

    abstract::Bipolar disorder (BD) adversely affects daily activities/functioning. The Sheehan Disability Scale (SDS) assesses disability in work/school activities, family relationships, and social functioning, and it evaluates the functional impact of psychiatric disorders. BD outpatients from 21 U.S. sites completed a battery of...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Arbuckle R,Frye MA,Brecher M,Paulsson B,Rajagopalan K,Palmer S,Degl' Innocenti A

    更新日期:2009-01-30 00:00:00

  • Effect of clozapine on white matter integrity in patients with schizophrenia: a diffusion tensor imaging study.

    abstract::Several diffusion tensor imaging (DTI) studies have reported disturbed white matter integrity in various brain regions in patients with schizophrenia, whereas only a few studied the effect of antipsychotics on DTI measures. The aim of this study was to investigate the effect of 12 weeks of clozapine treatment on DTI f...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Ozcelik-Eroglu E,Ertugrul A,Oguz KK,Has AC,Karahan S,Yazici MK

    更新日期:2014-09-30 00:00:00

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    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Freeman EW,DeRubeis RJ,Rickels K

    更新日期:1996-11-15 00:00:00

  • Light to moderate alcohol use is associated with increased cortical gray matter in middle-aged men: a voxel-based morphometric study.

    abstract::We examined the associations of current alcohol consumption with brain morphometric measures in a healthy, community-dwelling cohort. Cranial T1-weighted 3D-structural MRI scans were obtain in 383 adults (men=211) aged 60-64 years, randomly selected form the larger PATH Through Life study. Voxel-based morphometric ana...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Sachdev PS,Chen X,Wen W,Anstey KJ

    更新日期:2008-05-30 00:00:00

  • Abnormal processing of irrelevant information in chronic schizophrenia: selective enhancement of Stroop facilitation.

    abstract::Thirteen medication-free chronic schizophrenic patients and 11 normal control subjects were administered a trial by trial version of the Stroop Color Naming Task which evaluated separately the processes of interference and facilitation. There was no difference between the groups in the amount of interference to naming...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Carter CS,Robertson LC,Nordahl TE

    更新日期:1992-02-01 00:00:00

  • Does minimizing neuroleptic dosage influence hyponatremia?

    abstract::Neuroleptic dosage was reduced by 10% every 2 weeks in five male hyponatremic polydipsic patients with schizophrenia. Mean dose fell from 1980 +/- 1289 to 631 +/- 135 chlorpromazine equivalents/day over a mean of 12.2 weeks until behavioral relapse occurred. During this time, serum sodium did not vary from baseline le...

    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Canuso CM,Goldman MB

    更新日期:1996-07-31 00:00:00