Association Splitting: A randomized controlled trial of a new method to reduce craving among inpatients with alcohol dependence.

Abstract:

:Association Splitting, a novel cognitive intervention, was tested in patients with alcohol dependence as an add-on intervention in an initial randomized controlled trial. Preliminary support for Association Splitting has been found in patients with obsessive-compulsive disorder, as well as in an online pilot study of patients with alcohol use disorders. The present variant sought to reduce craving by strengthening neutral associations with alcohol-related stimuli, thus, altering cognitive networks. Eighty-four inpatients with verified diagnoses of alcohol dependence, who were currently undergoing inpatient treatment, were randomly assigned to Association Splitting or Exercise Therapy. Craving was measured at baseline, 4-week follow-up, and six months later with the Obsessive-Compulsive Drinking Scale (primary outcome) and the Alcohol Craving Questionnaire. There was no advantage for Association Splitting after three treatment sessions relative to Exercise Therapy. Among Association Splitting participants, 51.9% endorsed a subjective decline in craving and 88.9% indicated that they would use Association Splitting in the future. Despite high acceptance, an additional benefit of Association Splitting beyond standard inpatient treatment was not found. Given that participants were concurrently undergoing inpatient treatment and Association Splitting has previously shown moderate effects, modification of the study design may improve the potential to detect significant effects in future trials.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Schneider BC,Moritz S,Hottenrott B,Reimer J,Andreou C,Jelinek L

doi

10.1016/j.psychres.2016.02.051

subject

Has Abstract

pub_date

2016-04-30 00:00:00

pages

310-317

eissn

0165-1781

issn

1872-7123

pii

S0165-1781(15)30207-9

journal_volume

238

pub_type

杂志文章,随机对照试验
  • Testing a new interpersonal model of disordered eating between Australian and East-Asian women: The relationships between theory of mind, maladaptive schemas, and appearance-based rejection sensitivity.

    abstract::The current study tested a new interpersonal model of disordered eating behaviours, whereby maladaptive schemas and theory of mind decoding (ToM-decoding) were related with disordered eating attitudes (body dissatisfaction) and behaviours (binging/purging and food restriction) through the mediating variable appearance...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2019.02.065

    authors: Kimball H,Fuller-Tyszkiewicz M,De Paoli T,McKinlay A,Krug I

    更新日期:2019-05-01 00:00:00

  • A variable number of tandem repeats in the serotonin transporter gene does not affect the antidepressant response to fluvoxamine.

    abstract::A variable number of tandem repeats (VNTR) in the second intron of the serotonin transporter gene (STin2) has been studied in association with the susceptibility to affective disorders. Recently, it was reported that selective serotonin reuptake inhibitors were more effective in patients with major depressive disorder...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0165-1781(02)00141-5

    authors: Ito K,Yoshida K,Sato K,Takahashi H,Kamata M,Higuchi H,Shimizu T,Itoh K,Inoue K,Tezuka T,Suzuki T,Ohkubo T,Sugawara K,Otani K

    更新日期:2002-08-30 00:00:00

  • The association of MHPG to dexamethasone suppression test status.

    abstract::The results of the dexamethasone suppression test (DST) were compared to levels of 24-hour 3-methoxy-4-hydroxyphenylglycol (MHPG) in 60 patients with unipolar depression. DST nonsuppressors had significantly higher levels of MHPG than did DST suppressors. The possible implications of this finding are discussed. ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(88)90065-0

    authors: Garvey MJ,Hollon S,Evans M,DeRubeis RJ,Tuason VB

    更新日期:1988-05-01 00:00:00

  • Brain structure and function correlates of cognitive subtypes in schizophrenia.

    abstract::Stable neuropsychological deficits may provide a reliable basis for identifying etiological subtypes of schizophrenia. The aim of this study was to identify clusters of individuals with schizophrenia based on dimensions of neuropsychological performance, and to characterize their neural correlates. We acquired neurops...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2015.08.008

    authors: Geisler D,Walton E,Naylor M,Roessner V,Lim KO,Charles Schulz S,Gollub RL,Calhoun VD,Sponheim SR,Ehrlich S

    更新日期:2015-10-30 00:00:00

  • Children and adolescents attempting to participate in a worldwide online depression screener.

    abstract::Depression rates are increasing among minors. Internet is central to the lives of many minors, and many of them look online for depression information. This report describes minors who attempted to screen themselves for depression in a worldwide online study. Google Ads were used to recruit individuals to a multilingu...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2020.113250

    authors: Stephens TN,Tran MM,Bunge EL,Liu NH,Barakat S,Garza M,Leykin Y

    更新日期:2020-09-01 00:00:00

  • Age at onset of bipolar II depressive mixed state.

    abstract::Depressive mixed state (DMS) (a major depressive episode [MDE] with some concurrent hypomanic symptoms) is understudied. The aims of the study were to find if the prevalence of DMS, and its clinical correlates, in bipolar II depressed outpatients changed according to bipolar II age at onset. A consecutive sample of 92...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0165-1781(01)00258-x

    authors: Benazzi F

    更新日期:2001-09-20 00:00:00

  • Neuropsychological correlates of P300 abnormalities in patients with schizophrenia and obsessive-compulsive disorder.

    abstract::The cognitive significance of P300 abnormalities in schizophrenia and obsessive-compulsive disorder (OCD) was investigated. P300 was measured by an auditory oddball paradigm, in which a series of standard tones (1000 Hz) and target tones (1500 Hz) were presented. The subject's task was to count the number of the prese...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0925-4927(03)00045-3

    authors: Kim MS,Kang SS,Youn T,Kang DH,Kim JJ,Kwon JS

    更新日期:2003-06-30 00:00:00

  • Effectiveness of electroconvulsive therapy in patients with treatment resistant schizophrenia: A retrospective study.

    abstract::This study aimed to evaluate the effectiveness of electroconvulsive therapy (ECT) among patients with treatment resistant schizophrenia (TRS). Records of patients who had received ECT were reviewed to identify patients with TRS who were administered ECT in combination with clozapine. Socio-demographic, clinical data a...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.01.042

    authors: Grover S,Chakrabarti S,Hazari N,Avasthi A

    更新日期:2017-03-01 00:00:00

  • Subthreshold body dysmorphic disorder in adolescents: Prevalence and impact.

    abstract::The aim of the current study was to establish the prevalence of subthreshold body dysmorphic disorder (subthreshold-BDD) in a community sample of adolescents, and to compare disorder correlates in individuals with subthreshold-BDD to those with probable full-syndrome BDD (probable-BDD) and those without BDD (non-BDD)....

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.01.085

    authors: Schneider SC,Mond J,Turner CM,Hudson JL

    更新日期:2017-05-01 00:00:00

  • The psychological impact of the COVID-19 epidemic on college students in China.

    abstract::A COVID-19 epidemic has been spreading in China and other parts of the world since December 2019. The epidemic has brought not only the risk of death from infection but also unbearable psychological pressure. We sampled college students from Changzhi medical college by using cluster sampling. They responded to a quest...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2020.112934

    authors: Cao W,Fang Z,Hou G,Han M,Xu X,Dong J,Zheng J

    更新日期:2020-05-01 00:00:00

  • Stigma and its correlates among patients with bipolar disorder: A study from a tertiary care hospital of North India.

    abstract::This study aimed to assess stigma and its sociodemographic and clinical correlates among patients with bipolar disorder while in remission. 185 patients currently in remission were assessed on Internalized Stigma of Mental Illness Scale (ISMIS) for internalized stigma, Explanatory Model Interview Catalogue Stigma Scal...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2016.07.012

    authors: Grover S,Hazari N,Aneja J,Chakrabarti S,Avasthi A

    更新日期:2016-10-30 00:00:00

  • Temporal changes in attention to sad and happy faces distinguish currently and remitted depressed individuals from never depressed individuals.

    abstract::Depression is associated with attentional biases for emotional information that are proposed to reflect stable vulnerability factors for the development and recurrence of depression. A key question for researchers is whether those who have recovered from depression also exhibit attentional biases, and if so, how simil...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2015.09.036

    authors: Soltani S,Newman K,Quigley L,Fernandez A,Dobson K,Sears C

    更新日期:2015-12-15 00:00:00

  • The association between alexithymia as assessed by the 20-item Toronto Alexithymia Scale and depression: A meta-analysis.

    abstract::Patients with depression exhibit high rates of alexithymia, representing a major public health concern. We sought to examine relationships between depression severity and alexithymia as assessed by the Toronto Alexithymia Scale (TAS-20) and the TAS-20 subscales of difficulty identifying feelings (DIF), difficulty desc...

    journal_title:Psychiatry research

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.psychres.2015.02.006

    authors: Li S,Zhang B,Guo Y,Zhang J

    更新日期:2015-05-30 00:00:00

  • Treating conduct disorder: An effectiveness and natural language analysis study of a new family-centred intervention program.

    abstract::This paper reports on a new family-centred, feedback-informed intervention focused on evaluating therapeutic outcomes and language changes across treatment for conduct disorder (CD). The study included 26 youth and families from a larger randomised, controlled trial (Ronan et al., in preparation). Outcome measures ref...

    journal_title:Psychiatry research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.psychres.2016.11.035

    authors: Stevens KA,Ronan PK,Davies G

    更新日期:2017-05-01 00:00:00

  • Pre- and post-disaster negative life events in relation to the incidence and severity of post-traumatic stress disorder.

    abstract::There is evidence suggesting that stressful life events may precede major psychiatric illness, such as major depression, and that the severity of a traumatic event outside the range of usual human experience may provoke post-traumatic stress disorder (PTSD). The present study was carried out to examine the effects of ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0165-1781(01)00325-0

    authors: Maes M,Mylle J,Delmeire L,Janca A

    更新日期:2001-12-15 00:00:00

  • A case of extended-release Quetiapine causing recurrent low-grade fevers.

    abstract::This case highlights recurrent low-grade fevers caused by extended-release Quetiapine (Quetiapine XR), a previously unreported side effect, in a patient with Schizophreniform Disorder. While there have been case reports of Quetiapine causing neuroleptic malignant syndrome, there is paucity of data specifically describ...

    journal_title:Psychiatry research

    pub_type: 信件

    doi:10.1016/j.psychres.2020.113583

    authors: Puthran R,Lai D

    更新日期:2021-01-01 00:00:00

  • High velocity circuit resistance training improves cognition, psychiatric symptoms and neuromuscular performance in overweight outpatients with severe mental illness.

    abstract::We developed a physical exercise intervention aimed at improving multiple determinants of physical performance in severe mental illness. A sample of 12 (9M, 3F) overweight or obese community-dwelling patients with schizophrenia (n=9) and bipolar disorder (n=3) completed an eight-week, high-velocity circuit resistance ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2015.07.007

    authors: Strassnig MT,Signorile JF,Potiaumpai M,Romero MA,Gonzalez C,Czaja S,Harvey PD

    更新日期:2015-09-30 00:00:00

  • Altered functional connectivity of the insular cortex across prefrontal networks in cocaine addiction.

    abstract::Interoception is theorized to be an important process mediating substance use disorders, and the insular cortex is recognized as a core neural region supporting interoception. The purpose of this study was to compare the integration of the insular cortex into prefrontal-related resting-state networks between individua...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2013.02.007

    authors: Cisler JM,Elton A,Kennedy AP,Young J,Smitherman S,Andrew James G,Kilts CD

    更新日期:2013-07-30 00:00:00

  • A comparison of paroxetine versus paroxetine plus amisulpride in the treatment of dysthymic disorder: efficacy and psychosocial outcomes.

    abstract::Dysthymic disorder is a chronic depressive condition with considerable psychosocial impairment. Even if DD patients respond to various antidepressant medications, there has been little systematic study on antidepressant-refractory DD. Only a few trials have evaluated the effects of treatment on psychosocial functionin...

    journal_title:Psychiatry research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0165-1781(02)00188-9

    authors: Rocca P,Marchiaro L,Rasetti R,Rivoira E,Bogetto F

    更新日期:2002-10-10 00:00:00

  • Disordered eating behaviors in adolescents and adults living in the same household in metropolitan area of Rio de Janeiro, Brazil.

    abstract:OBJECTIVE:To examine the prevalence of disordered eating behaviors among adolescents and adults living in the same household. METHODS:We conducted a population-based cross-sectional study developed with a probabilistic sample of 511 adolescents and 1254 adults living in the metropolitan area of Rio de Janeiro, Brazil....

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2013.06.021

    authors: Ferreira JE,de Souza PR Jr,da Costa RS,Sichieri R,da Veiga GV

    更新日期:2013-12-15 00:00:00

  • The power to resist: the relationship between power, stigma, and negative symptoms in schizophrenia.

    abstract::Stigmatizing beliefs about mental illness can be a daily struggle for people with schizophrenia. While investigations into the impact of internalizing stigma on negative symptoms have yielded mixed results, resistance to stigmatizing beliefs has received little attention. In this study, we examined the linkage between...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2013.11.020

    authors: Campellone TR,Caponigro JM,Kring AM

    更新日期:2014-02-28 00:00:00

  • Ability to use the wait-and-see strategy in pathological gamblers.

    abstract::Pathological gamblers (PGs) perform differently on neurocognitive tests than do healthy controls (HC). The aim of this study was to assess "waiting ability" - a major components of inhibition control-using a modified Stop Signal Task (SST) in a population of male PGs (N=55), and HCs (N=53). Results indicated no differ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2015.09.038

    authors: Kertzman S,Vainder M,Visne T,Aizer A,Kotler M,Dannon PN

    更新日期:2015-12-15 00:00:00

  • Discerning the latent structure of hypothetical psychosis proneness through admixture analysis.

    abstract::The application of psychometric procedures to a normal population sample to detect individuals with increased liability for schizophrenia is a useful methodological adjunct to the traditional genetic high-risk strategy. A necessary and reasonable step in the process of establishing the utility of a viable psychometric...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(90)90041-3

    authors: Lenzenweger MF,Moldin SO

    更新日期:1990-09-01 00:00:00

  • Significant association of mu-opioid receptor 1 haplotype with tobacco smoking in healthy control subjects but not in patients with schizophrenia and alcohol dependence.

    abstract::Tobacco smoking is highly prevalent in patients with schizophrenia and alcohol dependence. The underlying neurobiology of nicotine addiction is complex. Rewarding effects of nicotine from cigarettes are associated, among others, with mu-opioid receptors encoded by the OPRM1 gene. The aim of the study was to evaluate t...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2020.113278

    authors: Konjevod M,Nikolac Perkovic M,Svob Strac D,Uzun S,Nedic Erjavec G,Kozumplik O,Tudor L,Mimica N,Hirasawa-Fujita M,Domino EF,Pivac N

    更新日期:2020-09-01 00:00:00

  • Seasonal trends in depressive problems among United States children and adolescents: a representative population survey.

    abstract::This study examined season-of-assessment differences in parent and child reports of depressive problems on well-validated instruments in 2009 U.S. children and adolescents, aged 6 to 18 years, from a nationally representative population survey. A parent completed the Child Behavior Checklist (CBCL) for each participan...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2008.07.011

    authors: Nillni YI,Rohan KJ,Rettew D,Achenbach TM

    更新日期:2009-12-30 00:00:00

  • Altered pineal serotonin binding in some suicides.

    abstract::Serotonergic abnormalities have been regularly reported in the brains of suicide victims. Because of evidence that pineal function is altered in depressed subjects and that serotonin-releasing axons may innervate the pineal, we assayed tritiated serotonin binding in a series of control and suicide pineals. High affini...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(90)90131-n

    authors: Sparks DL,Little KY

    更新日期:1990-04-01 00:00:00

  • The association between suicidal ideation and sleep quality in elderly individuals: A cross-sectional study in Shandong, China.

    abstract::Previous studies have identified global associations between sleep quality and suicidal ideation. However, little is known regarding the relationship between sleep quality and suicidal ideation among Chinese older adults. We examined the relationship between sleep quality and suicidal ideation in older adults in China...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.07.017

    authors: Qian Y,Sun L,Zhou C,Ge D,Zhang L

    更新日期:2017-10-01 00:00:00

  • The independence of schizotypy from affective temperaments--a combined confirmatory factor analysis of SPQ and the short TEMPS-A.

    abstract::Sparse evidence of a co-aggregation of the risk of schizophrenia and bipolar disorder provides support for a shared but nonspecific genetic etiology of bipolar disorder and schizophrenia. Temperaments are conceptualized as trait sub-syndromic conditions of major pathologies. This study set out to test the hypothesis o...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2014.10.027

    authors: Preti A,Corrias I,Gabbrielli M,Lai V,Muratore T,Pintus E,Pintus M,Sanna S,Scanu R,Tronci D,Vellante M,Siddi S,Petretto DR,Carta MG

    更新日期:2015-01-30 00:00:00

  • Statistical procedures for analyzing mental health services data.

    abstract::In mental health services research, analyzing service utilization data often poses serious problems, given the presence of substantially skewed data distributions. This article presents a non-technical introduction to statistical methods specifically designed to handle the complexly distributed datasets that represent...

    journal_title:Psychiatry research

    pub_type: 杂志文章,评审

    doi:10.1016/j.psychres.2007.07.003

    authors: Elhai JD,Calhoun PS,Ford JD

    更新日期:2008-08-15 00:00:00

  • Imitation of facial expressions in schizophrenia.

    abstract::Diminished facial expressivity is a common feature of schizophrenia that interferes with effective interpersonal communication. This study was designed to determine if real-time visual feedback improved the ability of patients with schizophrenia to imitate and produce modeled facial expressions. Twenty patients with s...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2005.12.007

    authors: Schwartz BL,Mastropaolo J,Rosse RB,Mathis G,Deutsch SI

    更新日期:2006-12-07 00:00:00