The association between alexithymia as assessed by the 20-item Toronto Alexithymia Scale and depression: A meta-analysis.

Abstract:

:Patients with depression exhibit high rates of alexithymia, representing a major public health concern. We sought to examine relationships between depression severity and alexithymia as assessed by the Toronto Alexithymia Scale (TAS-20) and the TAS-20 subscales of difficulty identifying feelings (DIF), difficulty describing feelings (DDF), and externally oriented thinking (EOT). Potentially relevant studies were obtained independently by two reviewers. Chi-square statistics based on the Q-test and I(2) index assessed statistical heterogeneity between studies. Subgroup analyses were mainly used to explore sources of heterogeneity. Begg׳s test and Duval and Tweedie' trim and fill were used to assess potential publication bias. Altogether, 3572 subjects from 20 study groups across 19 studies were included. Medium relationships were observed between depression and TAS-total score (TAS-TS), DIF, and DDF. There was also a weak relationship between EOT and depression. Subgroup analyses showed a stronger correlation between TAS-TS and depression assessed by self-reported tools than that assessed by the Hamilton Rating Scale for Depression. The heterogeneity significantly decreased only in the subgroup analysis by depression tool. We conclude that alexithymia, as assessed by the TAS-20 and its subscales DIF and DDF, is closely related to depression. These relationships were affected by depression measurement tools.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Li S,Zhang B,Guo Y,Zhang J

doi

10.1016/j.psychres.2015.02.006

subject

Has Abstract

pub_date

2015-05-30 00:00:00

pages

1-9

issue

1

eissn

0165-1781

issn

1872-7123

pii

S0165-1781(15)00076-1

journal_volume

227

pub_type

杂志文章,meta分析,评审
  • Illness severity, trait anxiety, cognitive impairment and heart rate variability in bipolar disorder.

    abstract::Numerous studies have documented a significant association between symptom severity and cognitive functioning in bipolar disorder (BD). These findings advanced speculations about a potential link between the physiological stress associated with illness severity and cognitive dysfunction. To explore this hypothesis, th...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2014.07.059

    authors: Levy B

    更新日期:2014-12-30 00:00:00

  • A systematic review of treatments for Impulse Control Disorders and related behaviours in Parkinson's disease.

    abstract::Impulse Control Disorders (ICDs) are a set of behaviours characterised by impulsivity despite known harm. Related to ICDs is the dopamine dysregulation syndrome (DDS), which is characterised by an addiction-like consumption of dopaminergic medication and punding. These behaviours all have an increased prevalence in Pa...

    journal_title:Psychiatry research

    pub_type: 杂志文章,评审

    doi:10.1016/j.psychres.2014.12.005

    authors: Tanwani P,Fernie BA,Nikčević AV,Spada MM

    更新日期:2015-02-28 00:00:00

  • Effects of electroconvulsive shock on neuro-immune responses: Does neuro-damage occur?

    abstract::Electroconvulsive therapy (ECT) is one of the most effective treatments for treatment-resistant depression. However, this treatment may produce memory impairment. The mechanisms of the cognitive adverse effects are not known. Neuroimmune response is related to the cognitive deficits. By reviewing the available animal ...

    journal_title:Psychiatry research

    pub_type: 杂志文章,评审

    doi:10.1016/j.psychres.2020.113289

    authors: An X,Shi X

    更新日期:2020-10-01 00:00:00

  • Assertive outreach for "difficult to engage" patients: A useful tool for a subgroup of patients in specialized early psychosis intervention programs.

    abstract:PURPOSE:Most specialized Early Psychosis (EP) programs include assertive outreach (AO) principles, either for all patients or as an intensive case management (ICM) subprogram in selected situations. The objective of this study is to examine prevalence, characteristics and outcomes of patients who needed additional ICM ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2016.03.010

    authors: Alameda L,Golay P,Baumann P,Morandi S,Ferrari C,Conus P,Bonsack C

    更新日期:2016-05-30 00:00:00

  • Gender differences in delusional disorder: Evidence from an outpatient sample.

    abstract::Our objective was to study gender differences in delusional disorder (DD), by comparing potential risk factors, clinical correlates, illness course characteristics, and functionality. The sample was composed of 86 outpatients with DD (according to the SCID-I for DSM-IV criteria). The following assessment instruments w...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2010.02.017

    authors: de Portugal E,González N,Miriam V,Haro JM,Usall J,Cervilla JA

    更新日期:2010-05-15 00:00:00

  • Indices of noradrenergic output in depression.

    abstract::Concentrations of plasma norepinephrine (NE) and plasma-3-methoxy-4-hydroxyphenylglycol (MHPG), blood pressure, and heart rate were measured on 2 days in 25 depressed patients and 25 controls. Comparisons were made between patients and controls, and also between days for both groups, to determine the short-term stabil...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(86)90093-4

    authors: Siever LJ,Uhde TW,Jimerson DC,Lake CR,Kopin IJ,Murphy DL

    更新日期:1986-09-01 00:00:00

  • The brain effects of cannabis in healthy adolescents and in adolescents with schizophrenia: a systematic review.

    abstract::Cannabis is widely used in adolescence; however, the effects of cannabis on the developing brain remain unclear. Cannabis might be expected to have increased effects upon brain development and cognition during adolescence. There is extensive re-organisation of grey (GM) and white matter (WM) at this time, while the en...

    journal_title:Psychiatry research

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.pscychresns.2013.07.012

    authors: James A,James C,Thwaites T

    更新日期:2013-12-30 00:00:00

  • Thalamic hypofunction in alcohol hallucinosis: FDG PET findings.

    abstract::We report findings obtained with positron emission tomography with fluorodeoxyglucose-F18 (FDG PET) as tracer in two patients with acute alcohol hallucinosis. In line with previous findings, both patients had a significant hypometabolism in the left relative to the right thalamus. When the second patient was retested ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2005.05.009

    authors: Soyka M,Koch W,Tatsch K

    更新日期:2005-08-30 00:00:00

  • A lifestyle intervention for primary care patients with depression and anxiety: A randomised controlled trial.

    abstract::This study aimed to evaluate the efficacy of a diet and exercise lifestyle intervention on mental health outcomes for patients currently being treated for depression and/or anxiety in primary care. Patients (n=119) referred by general practitioners to the 12-week randomised controlled trial were assigned to either an ...

    journal_title:Psychiatry research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.psychres.2015.10.001

    authors: Forsyth A,Deane FP,Williams P

    更新日期:2015-12-15 00:00:00

  • Performance in multiple domains of social cognition in parents of patients with schizophrenia.

    abstract::Social cognition refers to a set of cognitive abilities that allow us to perceive and interpret social stimuli. Social cognition is affected in schizophrenia and impairments have also been documented in unaffected relatives, suggesting that social cognition may be related to a genetic vulnerability to the disease. Thi...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2014.07.055

    authors: Lavoie MA,Plana I,Jackson PL,Godmaire-Duhaime F,Bédard Lacroix J,Achim AM

    更新日期:2014-12-15 00:00:00

  • Relationship between psychological inflexibility and experiential avoidance and internet addiction: Mediating effects of mental health problems.

    abstract::Internet addiction became a major mental health problem in college student. Our objective was to examine the relationship between psychological inflexibility and experiential avoidance (PIEA) and Internet addiction (IA) and the mediating effects of mental health problem indicators. 500 college students (238 men and 26...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.07.021

    authors: Chou WP,Lee KH,Ko CH,Liu TL,Hsiao RC,Lin HF,Yen CF

    更新日期:2017-11-01 00:00:00

  • The relationship of self-reported subclinical obsessive-compulsive symptoms and impulsivity among adults with AD/HD.

    abstract::This study examined the degree to which subclinical obsessive-compulsive symptoms (SOCS) among individuals with Attention Deficit/Hyperactivity Disorder (AD/HD) were associated with response inhibition difficulties on a performance-based test. Participants consisted of 64 adults with AD/HD who completed the Conner׳s C...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2014.01.034

    authors: Brown FC,Katz LJ,Roth RM,Beers SR

    更新日期:2014-04-30 00:00:00

  • Do patients from the Democratic Republic of Congo with schizophrenia have facial emotion recognition deficits?

    abstract::Patients with schizophrenia can have difficulty recognizing emotion, and the impact of this difficulty on social functioning has been widely reported. However, earlier studies did not thoroughly explore how this deficit may vary according to emotion intensity, or how it may differ among individuals and across cultures...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2019.03.030

    authors: Kitoko GMB,Maurage P,Peyroux E,Ma Miezi SM,Gillain B,Constant E

    更新日期:2019-05-01 00:00:00

  • Cognitive predictors of reactive and proactive aggression in a forensic sample: A comparison with a non-clinical sample.

    abstract::This study aimed at examining cognitive predictors of reactive and proactive aggression in a forensic-psychiatric (n = 80) and a non-clinical sample (n = 98; Brugman et al., 2015). Three different cognitive predictors were incorporated: (1) attentional bias towards aggressive stimuli (measured with Emotional Stroop ta...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2018.08.095

    authors: Brugman S,Lobbestael J,Sack AT,Cima MJ,Schuhmann T,Emmerling F,Arntz A

    更新日期:2018-11-01 00:00:00

  • Stroop performance in pathological gamblers.

    abstract::Pathological gambling is a relatively prevalent psychiatric disorder that typically leads to severe family, social, legal, and occupational problems and is associated with a high rate of suicide attempts. Understanding the neurobiological basis of pathological gambling is a current focus of research, and emerging data...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2005.07.027

    authors: Kertzman S,Lowengrub K,Aizer A,Nahum ZB,Kotler M,Dannon PN

    更新日期:2006-05-30 00:00:00

  • Altered auditory processing in frontal and left temporal cortex in 22q11.2 deletion syndrome: a group at high genetic risk for schizophrenia.

    abstract::In order to investigate electroencephalographic (EEG) biomarkers of auditory processing for schizophrenia, we studied a group with a well known high-risk profile: patients with 22q11.2 deletion syndrome (22q11 DS) have a 30% risk of developing schizophrenia during adulthood. We performed high-density EEG source imagin...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2012.09.002

    authors: Rihs TA,Tomescu MI,Britz J,Rochas V,Custo A,Schneider M,Debbané M,Eliez S,Michel CM

    更新日期:2013-05-30 00:00:00

  • Neurobiological effects of lumbar puncture stress in psychiatric patients and healthy volunteers.

    abstract::Several existing laboratory-based stress paradigms have significant shortcomings for assessing neurobiological correlates of stress in healthy volunteers and severely ill psychiatric patients. We have examined neuroendocrine effects of stress associated with the lumbar puncture (LP) procedure in drug-free depressed an...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(88)90050-9

    authors: Breier A,Wolkowitz OM,Doran AR,Bellar S,Pickar D

    更新日期:1988-08-01 00:00:00

  • Emotional intelligence as a mediator between rumination and suicidal ideation among depressed inpatients: The moderating role of suicidal history.

    abstract::Suicide is a substantial public health problem, and it remains a serious cause of death in the world. Therefore, this study was designed to examine the relationships between brooding, reflection, emotional intelligence (assessed by performance-based test), and suicidal ideation; the mediation role of emotional intelli...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2015.05.046

    authors: Abdollahi A,Talib MA

    更新日期:2015-08-30 00:00:00

  • Relationship of birth season to clinical features, family history, and obstetric complication in schizophrenia.

    abstract::Birth in late winter and spring has been consistently shown to be a risk factor of schizophrenia. The relationship of late winter/spring birth to clinical characteristics and other putative risk factors, such as family history and obstetric complications, may provide clues to etiology. Data relating to season of birth...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(96)02868-5

    authors: Dassa D,Sham PC,van Os J,Abel K,Jones P,Murray RM

    更新日期:1996-08-30 00:00:00

  • The role of stressful life events preceding death by suicide: Evidence from two samples of suicide decedents.

    abstract::Stressful life events (SLEs) are associated with increased risk for suicidal behavior. Less is known regarding the intensity of SLEs and how this may vary as a function of suicide attempt history. As a large percentage of suicide decedents do not have a history of suicidal behavior, SLEs precipitating suicide may help...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.06.078

    authors: Buchman-Schmitt JM,Chu C,Michaels MS,Hames JL,Silva C,Hagan CR,Ribeiro JD,Selby EA,Joiner TE Jr

    更新日期:2017-10-01 00:00:00

  • Plasma norepinephrine responses to cold challenge in depressed patients and normal controls.

    abstract::Thirty depressed patients were compared with 39 controls for their plasma norepinephrine (NE) levels in relation to a cold challenge (placing a hand in ice cold water for 1 minute). Depressed patients showed significantly higher plasma NE levels than controls. Unipolar, but not bipolar patients, had significantly high...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(87)90073-4

    authors: Roy A,Guthrie S,Pickar D,Linnoila M

    更新日期:1987-06-01 00:00:00

  • Executive control in schizophrenia in task involving semantic inhibition and working memory.

    abstract::Executive dysfunctions have been consistently demonstrated in patients with schizophrenia. This study aimed to investigate deficits in specific executive functioning components, namely working memory and inhibition, in schizophrenia. In study 1, a set of neurocognitive function tests was administered to 41 patients wi...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2009.07.014

    authors: Chan RC,Huang J,Guo L,Cao X,Hong X,Gao Z

    更新日期:2010-10-30 00:00:00

  • Effect of clozapine dose and concentration on fasting concentration of appetite regulating peptides.

    abstract::The aim of this study is to analyze whether clozapine serum concentration may affect fasting serum levels of several appetite regulating peptides: CART, PYY(1-36), NPY, AgRP, des-acylated ghrelin, leptin and obestatin. Serum concentration of clozapine and fasting serum levels of des-acylated ghrelin, neuropeptide Y (N...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.12.018

    authors: Margulska A,Kozłowska E,Wysokiński A

    更新日期:2018-02-01 00:00:00

  • Pharmacogenetics of adverse events in schizophrenia treatment: comparison study of ziprasidone, olanzapine and perazine.

    abstract::The primary aim of the present study was to assess the possible associations between dopaminergic, serotonergic, and glutamatergic system-related genes and adverse events after antipsychotic treatment in paranoid schizophrenia patients. The second aim of the study was to compare the intensity of these symptoms between...

    journal_title:Psychiatry research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.psychres.2014.05.039

    authors: Tybura P,Trześniowska-Drukała B,Bienkowski P,Beszlej A,Frydecka D,Mierzejewski P,Samochowiec A,Grzywacz A,Samochowiec J

    更新日期:2014-10-30 00:00:00

  • Distress intolerance in the parents of substance dependent patients.

    abstract::The purpose of this study was to determine levels of Distress Tolerance (DT) and to compare levels of DT, depression, and anxiety in the parents of substance dependent patients. This sample included 40 parents of inpatients undergoing treatment for substance dependence (SDPP) in the Balıklı Rum Hospital, Istanbul, Tur...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2016.12.026

    authors: Ekinci S,Kural HU

    更新日期:2017-05-01 00:00:00

  • Depersonalization disorder and anxiety: a special relationship?

    abstract::A significant association between anxiety and depersonalization has been found in healthy controls and psychiatric patients irrespective of underlying conditions. Although patients with depersonalization disorder (DPD) often have a history of severe anxiety symptoms, clinical observations suggest that the relation bet...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2011.12.017

    authors: Sierra M,Medford N,Wyatt G,David AS

    更新日期:2012-05-15 00:00:00

  • Quality of life in schizophrenia spectrum disorders: associations with insight and psychopathology.

    abstract::Therapeutic interventions in chronic mental illness face the important challenge to pursuit the quality of life (QOL) of patients. Insight into chronic mental illness, though a prerequisite for treatment adherence and a positive therapeutic outcome, has shown adverse associations with subjective QOL. This study aims t...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2014.11.016

    authors: Margariti M,Ploumpidis D,Economou M,Christodoulou GN,Papadimitriou GN

    更新日期:2015-02-28 00:00:00

  • Impaired performance on the Rapid Visual Information Processing task (RVIP) could be an endophenotype of schizophrenia.

    abstract::The aim of the present study was to investigate whether healthy first-degree relatives of schizophrenia patients show reduced sensitivity performance, higher intra-individual variability (IIV) in reaction time (RT), and a steeper decline in sensitivity over time in a sustained attention task. Healthy first-degree rela...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2009.12.012

    authors: Hilti CC,Hilti LM,Heinemann D,Robbins T,Seifritz E,Cattapan-Ludewig K

    更新日期:2010-05-15 00:00:00

  • Social adjustment could be associated with the serotonin transporter gene in remitted patients with mood disorders and healthy subjects.

    abstract::We investigated the serotonin transporter gene (5-HTTLPR) in the functioning of euthymic patients with mood disorders (n=285) and healthy controls (n=94). The 5-HTTLPR genotype showed marginal associations with working, familial and social adjustment, with marked differences between controls and patients. Because of t...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2005.01.006

    authors: Serretti A,Mandelli L,Lorenzi C,Smeraldi E

    更新日期:2005-04-15 00:00:00

  • Negative affect predicts social functioning across schizophrenia and bipolar disorder: Findings from an integrated data analysis.

    abstract::Most people with a serious mental illness experience significant functional impairment despite ongoing pharmacological treatment. Thus, in order to improve outcomes, a better understanding of functional predictors is needed. This study examined negative affect, a construct comprised of negative emotional experience, a...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2016.06.031

    authors: Grove TB,Tso IF,Chun J,Mueller SA,Taylor SF,Ellingrod VL,McInnis MG,Deldin PJ

    更新日期:2016-09-30 00:00:00