The association between alexithymia as assessed by the 20-item Toronto Alexithymia Scale and depression: A meta-analysis.


:Patients with depression exhibit high rates of alexithymia, representing a major public health concern. We sought to examine relationships between depression severity and alexithymia as assessed by the Toronto Alexithymia Scale (TAS-20) and the TAS-20 subscales of difficulty identifying feelings (DIF), difficulty describing feelings (DDF), and externally oriented thinking (EOT). Potentially relevant studies were obtained independently by two reviewers. Chi-square statistics based on the Q-test and I(2) index assessed statistical heterogeneity between studies. Subgroup analyses were mainly used to explore sources of heterogeneity. Begg׳s test and Duval and Tweedie' trim and fill were used to assess potential publication bias. Altogether, 3572 subjects from 20 study groups across 19 studies were included. Medium relationships were observed between depression and TAS-total score (TAS-TS), DIF, and DDF. There was also a weak relationship between EOT and depression. Subgroup analyses showed a stronger correlation between TAS-TS and depression assessed by self-reported tools than that assessed by the Hamilton Rating Scale for Depression. The heterogeneity significantly decreased only in the subgroup analysis by depression tool. We conclude that alexithymia, as assessed by the TAS-20 and its subscales DIF and DDF, is closely related to depression. These relationships were affected by depression measurement tools.


Psychiatry Res


Psychiatry research


Li S,Zhang B,Guo Y,Zhang J




Has Abstract


2015-05-30 00:00:00














  • Thinner cortex in the frontal lobes in mentally disordered offenders.

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    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Howner K,Eskildsen SF,Fischer H,Dierks T,Wahlund LO,Jonsson T,Wiberg MK,Kristiansson M

    更新日期:2012-08-01 00:00:00

  • Effects of season on electro-oculographic ratio in winter seasonal affective disorder.

    abstract::Low electro-oculographic (EOG) ratios have been reported in patients with seasonal affective disorder (SAD) during the winter. This study evaluated the effects of the changing seasons on EOG ratios in SAD patients. Sixteen outpatients with SAD and 16 age-, sex-, and medication-matched normal volunteers had EOG testing...

    journal_title:Psychiatry research

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  • The correlation between the quality of life and clinical variables among outpatients with schizophrenia.

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    更新日期:1991-10-01 00:00:00

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    更新日期:1997-07-04 00:00:00

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    journal_title:Psychiatry research

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    authors: Trapp W,Kalzendorf C,Baum C,Hajak G,Lautenbacher S

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    pub_type: 临床试验,杂志文章,随机对照试验


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    authors: Parker G,Hyett M,Walsh W,Owen C,Brotchie H,Hadzi-Pavlovic D

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    pub_type: 杂志文章


    authors: Yamada K,Moriwaki K,Oiso H,Ishigooka J

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    更新日期:2017-04-01 00:00:00

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    journal_title:Psychiatry research

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    authors: Gulick D,Chau DT,Khokhar JY,Dawson R,Green AI

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    authors: Sartor CE,Scherrer JF,Shah KR,Xian H,Volberg R,Eisen SA

    更新日期:2007-07-30 00:00:00

  • Trauma and traumatic stress in a sample of pregnant women.

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    pub_type: 杂志文章


    authors: Gelaye B,Zhong QY,Basu A,Levey EJ,Rondon MB,Sanchez S,Koenen KC,Henderson DC,Williams MA

    更新日期:2017-11-01 00:00:00

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    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Eisenacher S,Rausch F,Mier D,Fenske S,Veckenstedt R,Englisch S,Becker A,Andreou C,Moritz S,Meyer-Lindenberg A,Kirsch P,Zink M

    更新日期:2016-04-30 00:00:00

  • Parental style and Cloninger's model in psychosis.

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    journal_title:Psychiatry research

    pub_type: 杂志文章


    authors: Mansueto G,Palmieri S,Faravelli C

    更新日期:2018-11-01 00:00:00