Abstract:
:Birth in late winter and spring has been consistently shown to be a risk factor of schizophrenia. The relationship of late winter/spring birth to clinical characteristics and other putative risk factors, such as family history and obstetric complications, may provide clues to etiology. Data relating to season of birth, clinical features, family history, and obstetric complications were analyzed for 192 patients with schizophrenia as defined by Research Diagnostic Criteria (including schizoaffective disorder). There was no significant association of season of birth with any of the psychopathological dimensions nor was there a significant association with obstetric variables or family history. However, winter-born schizophrenic patients who had a negative family history were more likely to have a history of obstetric complications. These findings suggest that obstetric complications associated with schizophrenia are perhaps the result of some seasonal risk factors important in those without a family history of the disorder.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Dassa D,Sham PC,van Os J,Abel K,Jones P,Murray RMdoi
10.1016/0165-1781(96)02868-5subject
Has Abstractpub_date
1996-08-30 00:00:00pages
11-7issue
1eissn
0165-1781issn
1872-7123pii
0165178196028685journal_volume
64pub_type
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