Relationship of birth season to clinical features, family history, and obstetric complication in schizophrenia.

Abstract:

:Birth in late winter and spring has been consistently shown to be a risk factor of schizophrenia. The relationship of late winter/spring birth to clinical characteristics and other putative risk factors, such as family history and obstetric complications, may provide clues to etiology. Data relating to season of birth, clinical features, family history, and obstetric complications were analyzed for 192 patients with schizophrenia as defined by Research Diagnostic Criteria (including schizoaffective disorder). There was no significant association of season of birth with any of the psychopathological dimensions nor was there a significant association with obstetric variables or family history. However, winter-born schizophrenic patients who had a negative family history were more likely to have a history of obstetric complications. These findings suggest that obstetric complications associated with schizophrenia are perhaps the result of some seasonal risk factors important in those without a family history of the disorder.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Dassa D,Sham PC,van Os J,Abel K,Jones P,Murray RM

doi

10.1016/0165-1781(96)02868-5

subject

Has Abstract

pub_date

1996-08-30 00:00:00

pages

11-7

issue

1

eissn

0165-1781

issn

1872-7123

pii

0165178196028685

journal_volume

64

pub_type

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