Abstract：
:Because estrogen may influence brain blood flow and metabolism in older adults, we used positron emission tomography to evaluate cerebral glucose metabolic change in post-menopausal women and men. Women estrogen users (n=4), women non-users (n=8) and men (n=10) were scanned at baseline and two years later. Analyses focused on glucose metabolism in lateral temporal, inferior parietal and posterior cingulate brain regions, previously reported to decline in non-demented older persons. No metabolic differences in cerebral regions of interest were found among groups at baseline. At follow-up, women estrogen users showed significantly increased glucose metabolism in the lateral temporal region, whereas women non-users and men exhibited no significant metabolic change in this region. These findings suggest that estrogen use may protect against regional cerebral metabolic decline in postmenopausal women.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Rasgon NL,Small GW,Siddarth P,Miller K,Ercoli LM,Bookheimer SY,Lavretsky H,Huang SC,Barrio JR,Phelps MEdoi
10.1016/s0925-4927(01)00084-1subject
Has Abstractpub_date
2001-07-01 00:00:00pages
11-8issue
1eissn
0165-1781issn
1872-7123pii
S0925492701000841journal_volume
107pub_type
杂志文章abstract：:MIR137, a brain expressed miRNA, has been identified as a top novel susceptibility gene for schizophrenia (SZ). 230 healthy participants completed the Stroop test and were genotyped for a functional Variable Number Tandem Repeat (VNTR) in MIR137 gene. MIR137 VNTR genotypes were associated with differences in Stroop fa...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2016.01.006
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pub_type： 杂志文章
doi：10.1016/0165-1781(86)90074-0
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abstract：:Left temporoparietal repetitive transcranial magnetic stimulation (rTMS) reportedly diminishes verbal hallucinations. A 21-year-old schizophrenic man, who had killed his mother in the belief that she was a demon, failed to respond to combined treatment with a variety of antipsychotic agents. His persistent hallucinati...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(03)00148-3
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abstract：:There is evidence from research based on self-report personality measures that schizophrenia patients tend to be lower in extraversion and higher in neuroticism than healthy individuals. Self-report personality measures assess aspects of the explicit self-concept. The Implicit Association Test (IAT) has been developed...
journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2014.04.023
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/s0165-1781(02)00128-2
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journal_title：Psychiatry research
pub_type： 杂志文章,meta分析
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journal_title：Psychiatry research
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journal_title：Psychiatry research
pub_type： 杂志文章
doi：10.1016/j.psychres.2004.11.007
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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journal_title：Psychiatry research
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journal_title：Psychiatry research
pub_type： 杂志文章
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