Neuropsychological prognosis and clinical recovery.

Abstract:

:This report examines prognostic implications of neuropsychological deficit for clinical symptomatic improvement. Neuropsychological performance levels are related to the Brief Psychiatric Rating Scale thinking disturbance, paranoid disturbance, withdrawal/retardation, and anxiety/depression scales at hospital admission and discharge in 68 schizophrenic and psychotic and nonpsychotic mood disorder patients. Findings indicate a relationship between neurocognitive deficit and thinking disturbance at admission; however, neuropsychological impairment predicts blunted affect/emotional withdrawal at discharge, after the acute psychopathology resolves. Neuropsychological deficit is nonspecific, occurring across a broad range of cognitive-perceptual functions. These data suggest that neuropsychological dysfunction may be prognostic of a more chronic residual disorder in both schizophrenia and major psychotic and nonpsychotic mood disorder syndromes.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Silverstein ML,Harrow M,Bryson GJ

doi

10.1016/0165-1781(94)90072-8

subject

Has Abstract

pub_date

1994-06-01 00:00:00

pages

265-72

issue

3

eissn

0165-1781

issn

1872-7123

pii

0165-1781(94)90072-8

journal_volume

52

pub_type

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