Hormone-dependent neural plasticity in the juvenile and adult song system: what makes a successful male?

abstract：:Over several years our group has sought to synthesize and identify selective ligands for imidazoline (I) receptors, in particular the I2 binding site. As a consequence, [3H]2-(2-benzofuranyl)-2-imidazoline (2BFI) has proved extremely useful for binding and autoradiographic studies. More recently we have synthesized a ...

journal_title：Annals of the New York Academy of Sciences

authors： Hudson AL,Gough R,Tyacke R,Lione L,Lalies M,Lewis J,Husbands S,Knight P,Murray F,Hutson P,Nutt DJ

更新日期：1999-06-21 00:00:00

abstract：:Rodent models have been used for many years to probe the actions of relaxin. Identification of the orthologs of human leucine-rich repeat-containing g-protein-coupled receptor 7 (LGR7), the relaxin receptor, in mouse and rat will enable characterization of the response of LGR7 to relaxin in these species. Partial LGR7...

journal_title：Annals of the New York Academy of Sciences

authors： Scott DJ,Layfield S,Riesewijk A,Morita H,Tregear GW,Bathgate RA

更新日期：2005-05-01 00:00:00

abstract：:The nonpregnant uterus shows uterine activity throughout the menstrual cycle. This uterine activity was detected both by single strep tissue and by using intrauterine pressure recordings in vitro and in vivo. Today, ultrasound has made it possible to study this activity with a noninvasive approach and to assess uterin...

journal_title：Annals of the New York Academy of Sciences

authors： Bulletti C,DE Ziegler D,Setti PL,Cicinelli E,Polli V,Flamigni C

更新日期：2004-12-01 00:00:00

abstract：:We are performing genomic searches in randomly ascertained families to identify new quantitative trait loci (QTLs) that influence atherosclerosis and its risk factors. The genetic markers used for genomic searches are random microsatellite markers distributed throughout the human chromosomes. These markers are used fo...

journal_title：Annals of the New York Academy of Sciences

authors： Hixson JE,Blangero J

更新日期：2000-05-01 00:00:00

abstract：:The nearly neutral theory represents a development of Kimura's neutral theory of molecular evolution that makes testable predictions that go beyond a mere null model. Recent evidence has strongly supported several of these predictions, including the prediction that slightly deleterious variants will accumulate in a sp...

journal_title：Annals of the New York Academy of Sciences

authors： Hughes AL

更新日期：2008-01-01 00:00:00

abstract：:The resolution of antibiotic-ribosomal subunit complexes and antibacterial-protein complexes at the atomic level has provided new insights into modifications of clinically relevant antimicrobials and provided new classes that target the protein cellular apparatus. New chemistry platforms that use fragment-based drug d...

journal_title：Annals of the New York Academy of Sciences

authors： Sutcliffe JA

更新日期：2011-12-01 00:00:00

abstract：:These findings demonstrate that calcium antagonists reverse renal vasoconstriction in a variety of settings. The ability of calcium antagonists to augment GFR of the vasoconstricted kidney is striking and has also been demonstrated in a number of in vivo settings. These observations and others raise the possibility th...

journal_title：Annals of the New York Academy of Sciences

authors： Loutzenhiser R,Epstein M

更新日期：1988-01-01 00:00:00

abstract：:Higher levels of body fat are associated with increased risk for development of numerous adverse health conditions. Phytochemicals are potential agents to inhibit differentiation of preadipocytes, stimulate lipolysis, and induce apoptosis of existing adipocytes, thereby reducing adipose tissue mass. Resveratrol decrea...

journal_title：Annals of the New York Academy of Sciences

authors： Baile CA,Yang JY,Rayalam S,Hartzell DL,Lai CY,Andersen C,Della-Fera MA

更新日期：2011-01-01 00:00:00

abstract：:Aging is the major risk factor for both the development of chronic diseases and loss of functional capacity. Geroscience provides links among the biology of aging, the biology of disease, and the physiology of frailty, three fields where enormous progress has been made in the last few decades. While, previously, the f...

journal_title：Annals of the New York Academy of Sciences

authors： Kohanski RA,Deeks SG,Gravekamp C,Halter JB,High K,Hurria A,Fuldner R,Green P,Huebner R,Macchiarini F,Sierra F

更新日期：2016-12-01 00:00:00

abstract：:We compared 10 episodes (8 patients) of Q fever endocarditis with 27 episodes (27 patients) of native valve endocarditis. Patients with Q fever endocarditis were more likely to have weight loss (p less than 0.003), experience fatigue (p less than 0.07), have clubbing of the fingers (p less than 0.005), have a diastoli...

journal_title：Annals of the New York Academy of Sciences

authors： Marrie TJ

更新日期：1990-01-01 00:00:00

abstract：:Flavonoids and phenolic acids are widely distributed in higher plants and form part of the human diet. Recent interest in these substances has been stimulated by the potential health benefits arising from the antioxidant activity of these polyphenolic compounds. This review outlines the basic chemistry, biosynthesis, ...

journal_title：Annals of the New York Academy of Sciences

authors： Croft KD

更新日期：1998-11-20 00:00:00

abstract：:Increasing evidence indicates that several mechanisms, associated or not with antioxidant actions, are involved in the effects of flavonoids on health. Flavonoid-rich beverages, foods, and extracts, as well as pure flavonoids are studied for the prevention and/or amelioration of metabolic syndrome (MS) and MS-associat...

journal_title：Annals of the New York Academy of Sciences

authors： Galleano M,Calabro V,Prince PD,Litterio MC,Piotrkowski B,Vazquez-Prieto MA,Miatello RM,Oteiza PI,Fraga CG

更新日期：2012-07-01 00:00:00

abstract：:The molecular archaeology of the mutation spectra of tumor suppressor genes generates hypotheses concerning the etiology and molecular pathogenesis of human cancer. The spectrum of somatic mutations in the p53 gene implicates environmental carcinogens and both endogenous agents and processes in the etiology of human c...

journal_title：Annals of the New York Academy of Sciences

authors： Hussain SP,Hollstein MH,Harris CC

更新日期：2000-01-01 00:00:00

abstract：:Nicergoline (NE)--a cerebral vasodilator with nicotinic acid esterified in its molecule--and Antagonic-Stress (AS) composition--a neurometabolic nootropic, also containing nicotinic acid but with fast and prolonged release--were evaluated in senile dementia of Alzheimer's type (SDAT), mild to moderate intensity (DSM-I...

journal_title：Annals of the New York Academy of Sciences

authors： Schneider F,Popa R,Mihalas G,Stefanigă P,Mihalas IG,Măties R,Mateescu R

更新日期：1994-06-30 00:00:00

abstract：:The advent of highly active anti-retroviral therapy (HAART) has dramatically decreased the rate of AIDS-related mortality and significantly extended the life span of patients with AIDS. A variety of metabolic side effects are associated with these therapies, one of which is metabolic bone disease. A higher prevalence ...

journal_title：Annals of the New York Academy of Sciences

authors： Pan G,Yang Z,Ballinger SW,McDonald JM

更新日期：2006-04-01 00:00:00

abstract：:Endometriosis is often a perplexing medical condition for both the physician and the patient. Accordingly, development of treatment strategies based on the needs of the individual patient is highly desirable. Although endometriosis has been part of the clinical practice for almost a century, many questions remain rela...

journal_title：Annals of the New York Academy of Sciences

authors： Valle RF,Sciarra JJ

更新日期：2003-11-01 00:00:00

abstract：:Cardiomyocytes in the adult mammal retain little or none of their developmental capacity for hyperplastic growth. As a consequence of this differentiated, nonproliferative phenotype, cardiomyocyte loss due to injury or disease is irreversible. Therapeutic intervention in end-stage diseased hearts is currently limited ...

journal_title：Annals of the New York Academy of Sciences

authors： Soonpaa MH,Daud AI,Koh GY,Klug MG,Kim KK,Wang H,Field LJ

更新日期：1995-03-27 00:00:00

abstract：:Neurotrophic factors are secreted peptides that when interacting with specific classes of membrane receptors activate intracellular signaling cascades that prevents neuronal death during embryonic development. The establishment of gene-targeted null mutant mice for the neurotrophic factors, brain-derived neurotrophic ...

journal_title：Annals of the New York Academy of Sciences

authors： Agerman K,Canlon B,Duan M,Ernfors P

更新日期：1999-11-28 00:00:00

abstract：:The aim of this study was to investigate the influence of long-lasting, extensive rowing training on body fluids in 12 experienced rowers (23.3 +/- 6.3 years, 188.7 +/- 5.9 cm, 82.0 +/- 10.8 kg, body mass index [BMI] 23.7 +/- 2.1). All rowers had a light traditional breakfast about 3 h before the training. The subject...

journal_title：Annals of the New York Academy of Sciences

authors： Jürimäe J,Jürimäe T,Pihl E

更新日期：2000-05-01 00:00:00

abstract：:We investigated Ca2+ clearance mechanisms (CCMs) at the axon terminals of mammalian central neurons: neurohypophysial (NHP) axon terminals and calyces of Held. Ca2+ transients were evoked by applying a short depolarization pulse via a patch pipette containing Ca2+ indicator dye. Quantitative analysis of the Ca2+ decay...

journal_title：Annals of the New York Academy of Sciences

authors： Lee SH,Kim MH,Lee JY,Lee SH,Lee D,Park KH,Ho WK

更新日期：2007-03-01 00:00:00

abstract：:The last decade has witnessed a surge in studies on steroid hormones of maternal origin present in avian eggs and affecting offspring development. The value of such studies for the understanding of maternal effects and individual differentiation is endorsed and a series of methodological and conceptual issues in the c...

journal_title：Annals of the New York Academy of Sciences

authors： Groothuis TG,von Engelhardt N

更新日期：2005-06-01 00:00:00

abstract：:Taxonomic characterization of organisms in the genera Theileria and Babesia was originally based on observations of morphology and certain general phenotypic characteristics, which enabled many parasites to be unequivocally assigned to a particular genus. However, application of molecular genetic techniques, such as t...

journal_title：Annals of the New York Academy of Sciences

authors： Allsopp MT,Allsopp BA

更新日期：2006-10-01 00:00:00

abstract：:Perhaps the greatest mystery is why the universe exists in the first place. How is it possible for something to emerge from nothing, or has a universe in some form always existed? This question of origins-both of the universe as a whole and of the fundamental laws of physics-raises profound scientific, philosophical, ...

journal_title：Annals of the New York Academy of Sciences

authors： Paulson S,Albert D,Holt J,Turok N

更新日期：2015-12-01 00:00:00

abstract：:Studies of animals with spontaneous autoimmune diabetes have revealed that autoreactive T cells that mediate islet beta cell destruction can be manipulated by the administration of Th(2) cytokines. Using gene delivery to express the targeted protein, we can overcome the need for frequent administration of cytokines on...

journal_title：Annals of the New York Academy of Sciences

authors： Park L,Lee E,Lee S,Lim M,Hong H,Shin G,Park Y

更新日期：2008-12-01 00:00:00

abstract：:The hypothesis tested was that mutant tumor DNA shed into plasma would show predictive value for monitoring response to therapy in non-small cell lung carcinoma patients. Pretreatment plasma specimens from 25 patients on a phase I trial were evaluated, 12 with paired posttreatment specimens, and 138 patients on the So...

journal_title：Annals of the New York Academy of Sciences

authors： Kimura T,Holland WS,Kawaguchi T,Williamson SK,Chansky K,Crowley JJ,Doroshow JH,Lenz HJ,Gandara DR,Gumerlock PH

更新日期：2004-06-01 00:00:00

abstract：:The ability to recognize and discriminate conspecific faces and facial expressions has played a critical role in the evolution of social communication. Darwin was one of the first to speculate that human and nonhuman primate facial expressions share similar mechanisms for production and functions in expressing emotion...

journal_title：Annals of the New York Academy of Sciences

authors： Parr LA

更新日期：2003-12-01 00:00:00

abstract：:Human female reproductive aging consists of multiple processes and interacts with other physiological systems in unique ways. Here we discuss eight recent longitudinal, epidemiologic studies of female reproductive aging that include endocrine data to highlight their contributions to our understanding of these various ...

journal_title：Annals of the New York Academy of Sciences

authors： Ferrell RJ,Sowers M

更新日期：2010-08-01 00:00:00

abstract：:This paper represents a unique effort to elucidate the dynamics of two major types of politically motivated hostage takers. The data presented are derived from an ongoing research project that is gathering extensive interview and psychological test materials from prisoners convicted of politically motivated crimes, bo...

journal_title：Annals of the New York Academy of Sciences

authors： Knutson JN

更新日期：1980-01-01 00:00:00

abstract：:Chronic hypoxic stimulation in mammals can induce several phenotypic changes, such as polycythemia, pulmonary vascular changes, pulmonary hypertension, and carotid body (CB) enlargement. These phenotypic alterations provide a tool to test whether an oxygen sensor candidate is involved in an organism's response to envi...

journal_title：Annals of the New York Academy of Sciences

authors： Baysal BE

更新日期：2006-08-01 00:00:00

abstract：:In recent years, different subphenotypes of obesity have been described, including metabolically healthy obesity (MHO), in which a proportion of obese individuals, despite excess body fat, remain free of metabolic abnormalities and increased cardiometabolic risk. In the absence of a universally accepted set of criteri...

journal_title：Annals of the New York Academy of Sciences

authors： Phillips CM

更新日期：2017-03-01 00:00:00