Human immunodeficiency virus type 1 gag-specific mucosal immunity after oral immunization with papillomavirus pseudoviruses encoding gag.

abstract：:The interrelationship of viral ribonucleic acid (RNA) and protein synthesis in cells infected by Sindbis virus was investigated. When cultures were treated with puromycin early in the course of infection, the synthesis of interjacent RNA (26S) was preferentially inhibited. A similar result was obtained by shifting cel...

journal_title：Journal of virology

authors： Scheele CM,Pfefferkorn ER

更新日期：1969-08-01 00:00:00

abstract：:The Ebola virus glycoprotein mucin-like domain (MLD) is implicated in Ebola virus cell entry and immune evasion. Using cryo-electron tomography of Ebola virus-like particles, we determined a three-dimensional structure for the full-length glycoprotein in a near-native state and compared it to that of a glycoprotein la...

journal_title：Journal of virology

authors： Tran EE,Simmons JA,Bartesaghi A,Shoemaker CJ,Nelson E,White JM,Subramaniam S

更新日期：2014-09-01 00:00:00

abstract：:The Epstein-Barr virus oriP, when examined with the use of in vitro nucleosome reconstitution, was found to exhibit a partial sparing of nucleosome assembly within the 3' dyad. Analysis of the homologous region containing the origin of replication of herpesvirus papio disclosed that sparing of nucleosome assembly was ...

journal_title：Journal of virology

authors： Sexton CJ,Pagano JS

更新日期：1989-12-01 00:00:00

abstract：:The genome of varicella-zoster virus (VZV) is a linear, double-stranded molecule of DNA composed of a long (L) region covalently linked to a short (S) region. The S region is capable of inverting relative to a fixed orientation of the L region, giving rise to two equimolar populations. We have investigated other forms...

journal_title：Journal of virology

authors： Kinchington PR,Reinhold WC,Casey TA,Straus SE,Hay J,Ruyechan WT

更新日期：1985-10-01 00:00:00

abstract：:In this report, we describe the isolation, molecular genetic mapping, and phenotypic characterization of vaccinia virus mutants resistant to cytosine arabinoside (araC) and phosphonoacetic acid (PAA). At 37 degrees C, 8 microM araC was found to prevent macroscopic plaque formation by wild-type virus and to cause a 10(...

journal_title：Journal of virology

authors： Taddie JA,Traktman P

更新日期：1993-07-01 00:00:00

abstract：:Neurotropic coronavirus induces acute encephalomyelitis and demyelination in mice. Infection of BALB/c (H-2(d)) mice expressing a dominant negative gamma interferon (IFN-gamma) receptor specifically in oligodendrocytes was examined to determine the influence of IFN-gamma signaling on pathogenesis. Inhibition of IFN-ga...

journal_title：Journal of virology

authors： Parra GI,Bergmann CC,Phares TW,Hinton DR,Atkinson R,Stohlman SA

更新日期：2010-03-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is a herpesvirus that infects cells by fusing its lipid envelope with the target cell membrane. The fusion process requires the actions of viral glycoproteins gH, gL, and gB for entry into epithelial cells and additionally requires gp42 for entry into B cells. To further study the roles of the...

journal_title：Journal of virology

authors： Kirschner AN,Omerovic J,Popov B,Longnecker R,Jardetzky TS

更新日期：2006-10-01 00:00:00

abstract：:The promoter of the major immediate-early (MIE) genes of human cytomegalovirus (HCMV), also referred to as the CMV promoter, possesses a cis-acting element positioned downstream of the TATA box between positions -14 and -1 relative to the transcription start site (+1). We determined the role of the cis-acting element ...

journal_title：Journal of virology

authors： Isomura H,Stinski MF,Kudoh A,Nakayama S,Murata T,Sato Y,Iwahori S,Tsurumi T

更新日期：2008-01-01 00:00:00

abstract：:The cloned transcription factor hepatocyte nuclear factor 1 (HNF1) transactivates transcription from the hepatitis B virus (HBV) large surface antigen promoter but does not influence the transcriptional activities of the other three HBV promoters. This indicates that this transcription factor can differentially influe...

journal_title：Journal of virology

authors： Raney AK,Easton AJ,Milich DR,McLachlan A

更新日期：1991-11-01 00:00:00

abstract：UNLABELLED:STING has emerged in recent years as a key player in orchestrating innate immune responses to cytosolic DNA and RNA derived from pathogens. However, the regulation of STING still remains poorly defined. In the present study, we investigated the mechanism of the regulation of STING expression in relation to t...

journal_title：Journal of virology

authors： Liu Y,Goulet ML,Sze A,Hadj SB,Belgnaoui SM,Lababidi RR,Zheng C,Fritz JH,Olagnier D,Lin R

更新日期：2016-09-29 00:00:00

abstract：:The administration of cyclophosphamide (50 to 100 mg/kg) at 48 to 72 h before removal of murine lung or spleen mononuclear cells for culture rendered DBA/2 mice incapable of generating an effective cytotoxic T-lymphocyte response to influenza A virus-infected cells. The cytotoxic T-lymphocyte precursor frequency to in...

journal_title：Journal of virology

authors： Merluzzi VJ,Welte K,Mertelsmann RH,Souza L,Boone T,Last-Barney K

更新日期：1984-07-01 00:00:00

abstract：:We have previously shown that the herpes simplex virus immediate-early regulatory protein ICP27 acts posttranscriptionally to affect mRNA processing (R. M. Sandri-Goldin and G. E. Mendoza, Genes Dev. 6:848-863, 1992). Specifically, in the presence of ICP27, spliced target mRNAs were decreased 5- to 10-fold in transfec...

journal_title：Journal of virology

authors： Hardwicke MA,Sandri-Goldin RM

更新日期：1994-08-01 00:00:00

abstract：:In some retroviruses, such as Rous sarcoma virus and prototype foamy virus, Gag proteins are known to shuttle between the nucleus and the cytoplasm and are implicated in nuclear export of the viral genomic unspliced RNA (gRNA) for subsequent encapsidation. A similar function has been proposed for human immunodeficienc...

journal_title：Journal of virology

authors： Grewe B,Hoffmann B,Ohs I,Blissenbach M,Brandt S,Tippler B,Grunwald T,Uberla K

更新日期：2012-03-01 00:00:00

abstract：:Various mechanisms are used by single-stranded RNA viruses to initiate and control their replication via the synthesis of replicative intermediates. In general, the same virus-encoded polymerase is responsible for both genome and antigenome strand synthesis from two different, although related promoters. Here we aimed...

journal_title：Journal of virology

authors： Deng T,Vreede FT,Brownlee GG

更新日期：2006-03-01 00:00:00

abstract：:Large polypeptides of the Bacillus anthracis protective antigen (PA) were inserted into an influenza A virus hemagglutinin glycoprotein (HA), and the chimeric proteins were functionally characterized and incorporated into infectious influenza viruses. PA domain 1', the region responsible for binding to the other toxin...

journal_title：Journal of virology

authors： Li ZN,Mueller SN,Ye L,Bu Z,Yang C,Ahmed R,Steinhauer DA

更新日期：2005-08-01 00:00:00

abstract：:Retroviruses integrate into cellular DNA nonrandomly. Lentiviruses such as human immunodeficiency virus type 1 (HIV-1) favor the bodies of active genes and gene-enriched transcriptionally active regions of chromosomes. The interaction between lentiviral integrase and the cellular protein lens epithelium-derived growth...

journal_title：Journal of virology

authors： Koh Y,Wu X,Ferris AL,Matreyek KA,Smith SJ,Lee K,KewalRamani VN,Hughes SH,Engelman A

更新日期：2013-01-01 00:00:00

abstract：:The mechanism by which murine polyomavirus penetrates cells and arrives at the nucleus, the site of viral replication, is not well understood. Simian virus 40 and JC virus, two closely related members of the polyomavirus subfamily, use caveola- and clathrin-mediated uptake pathways for entry, respectively. The data pr...

journal_title：Journal of virology

authors： Gilbert JM,Benjamin TL

更新日期：2000-09-01 00:00:00

abstract：:We previously established a genetic assay for retroviral Gag polyprotein multimerization (J. Luban, K. B. Alin, K. L. Bossolt, T. Humaran, and S. P. Goff, J. Virol. 66:5157-5160, 1992). Here we use this assay to demonstrate homomeric interactions between Gag polyproteins encoded by six different retroviruses. Of the G...

journal_title：Journal of virology

authors： Franke EK,Yuan HE,Bossolt KL,Goff SP,Luban J

更新日期：1994-08-01 00:00:00

abstract：:Type I interferon is induced shortly following viral infection and represents a first line of host defense against a majority of viral pathogens. Not surprisingly, both replication and latency of gammaherpesviruses, ubiquitous cancer-associated pathogens, are attenuated by type I interferon, although the mechanism of ...

journal_title：Journal of virology

authors： Mounce BC,Mboko WP,Kanack AJ,Tarakanova VL

更新日期：2014-02-01 00:00:00

abstract：:The mechanisms mediating protective immunity to hepatitis C virus (HCV) infection are incompletely understood because early infection in humans is rarely identified, particularly in those individuals who subsequently demonstrate spontaneous virus eradication. We have established a large national network of patients wi...

journal_title：Journal of virology

authors： Smyk-Pearson S,Tester IA,Klarquist J,Palmer BE,Pawlotsky JM,Golden-Mason L,Rosen HR

更新日期：2008-02-01 00:00:00

abstract：:Homozygous human immunodeficiency virus type 1 (HIV-1)-transgenic mice (Tg26) appear normal at birth but die within 3 to 4 weeks. The skin of these animals shows diffuse scaling and high-level expression of both HIV-1 mRNA and gp120. Previous experiments showed that treatment with human chorionic gonadatropin (hCG) pr...

journal_title：Journal of virology

authors： De SK,Devadas K,Notkins AL

更新日期：2002-11-01 00:00:00

abstract：:The mosquito-transmitted dengue virus (DENV) infects millions of people in tropical and subtropical regions. Maturation of DENV particles requires proper cleavage of the viral polyprotein, including processing of 8 of the 13 substrate cleavage sites by dengue virus NS2B/NS3 protease. With no available direct-acting an...

journal_title：Journal of virology

authors： Lin KH,Ali A,Rusere L,Soumana DI,Kurt Yilmaz N,Schiffer CA

更新日期：2017-04-28 00:00:00

abstract：:F proteins from baculovirus nucleopolyhedrovirus (NPV) group II members are the major budded virus (BV) viral envelope fusion proteins. They undergo furin-like proteolysis processing in order to be functional. F proteins from different baculovirus species have a long cytoplasmic tail domain (CTD), ranging from 48 (Spo...

journal_title：Journal of virology

authors： Long G,Pan X,Westenberg M,Vlak JM

更新日期：2006-11-01 00:00:00

abstract：:Exosomes are small vesicles secreted from cells that participate in intercellular communication events. Accumulating evidence demonstrates that host exosome pathways are hijacked by viruses and that virally modified exosomes contribute to virus spread and immune evasion. In the case of tumor viruses, recent findings s...

journal_title：Journal of virology

authors： Meckes DG Jr

更新日期：2015-05-01 00:00:00

abstract：:Using a DNA probe from an avian transforming virus, NK24, that contains the fos gene and that was newly isolated and characterized (M. Nishizawa, N. Goto, and S. Kawai, J. Virol. 61:3733-3740, 1987), we cloned and sequenced the chicken c-fos gene. Results showed that this gene, like the mouse or human c-fos gene, cont...

journal_title：Journal of virology

authors： Fujiwara KT,Ashida K,Nishina H,Iba H,Miyajima N,Nishizawa M,Kawai S

更新日期：1987-12-01 00:00:00

abstract：UNLABELLED:SSV-type integrases, encoded by fuselloviruses which infect the hyperthermophilic archaea of the Sulfolobales, are archaeal members of the tyrosine recombinase family. These integrases catalyze viral integration into and excision from a specific site on the host genome. In the present study, we have establis...

journal_title：Journal of virology

authors： Zhan Z,Zhou J,Huang L

更新日期：2015-11-01 00:00:00

abstract：:Homo-oligomeric runs were inserted into a spleen necrosis virus-based retrovirus vector to determine the nature and rate of mutations within runs of 10 to 12 identical nucleotides during a single replication cycle. Clones of helper cells containing integrated copies of retroviral vectors were used to produce virus for...

journal_title：Journal of virology

authors： Burns DP,Temin HM

更新日期：1994-07-01 00:00:00

abstract：:After incubation at 37 C for 2 or more days, Basal Medium Eagle (BME) supplemented with 25% fetal calf serum (FCS) was not able to support adequate growth of EB3 and other lines of Burkitt tumor cells. The medium did, however, increase, by a factor of about 10, the number of cells synthesizing herpes-type virus with w...

journal_title：Journal of virology

authors： Henle W,Henle G

更新日期：1968-03-01 00:00:00

abstract：:Nonenveloped viral capsids are metastable structures that undergo conformational changes during virus entry that lead to interactions of the capsid or capsid fragments with the cell membrane. For members of the Caliciviridae, neither the nature of these structural changes in the capsid nor the factor(s) responsible fo...

journal_title：Journal of virology

authors： Ossiboff RJ,Zhou Y,Lightfoot PJ,Prasad BV,Parker JS

更新日期：2010-06-01 00:00:00

abstract：:Yaba tumor poxvirus deoxyribonucleic acid (DNA) has a density of 1.6905 in CsCl and its T(m) value in 0.015 m citrate in saline is 82.3. The guanine plus cytosine content estimated from these properties was taken to be 32.5 +/- 0.5%, a value 2 to 3% less than for DNA from other poxviruses reported to date. ...

journal_title：Journal of virology

authors： Yohn DS,Gallagher JF

更新日期：1969-02-01 00:00:00