Some physiochemical properties of Yaba poxvirus deoxyribonucleic acid.

abstract：:Mouse mammary tumor virus (MTV) was isolated from the milk of RIII mice by density-gradient centrifugation in Ficoll. The homogeneity of the preparation was demonstrated in electron micrographs. The nucleic acid was extracted with phenol in the presence of Pronase. Its viral origin was attested by failure of ribo-nucl...

journal_title：Journal of virology

authors： Sarkar NH,Moore DH

更新日期：1970-02-01 00:00:00

abstract：:The transcription map of the Aedes albopictus densovirus (AalDNV) brevidensovirus was identified by Northern blotting, rapid amplification of cDNA ends (RACE) analysis, and RNase protection assays. AalDNV produced mRNAs of 3,359 (NS1), 3,345 (NS2), and 1,246 (VP) nucleotides. The two overlapping P7/7.4 NS promoters em...

journal_title：Journal of virology

authors： Pham HT,Jousset FX,Perreault J,Shike H,Szelei J,Bergoin M,Tijssen P

更新日期：2013-09-01 00:00:00

abstract：:The presence of cycloheximide, an inhibitor of protein synthesis, during the period 30 to 60 min after vaccinia infection produced an irreversible block in virus replication. In contrast (i) cycloheximide given at earlier or later times, even for prolonged periods, did not prevent continuation of the infectious cycle ...

journal_title：Journal of virology

authors： Mss B,Filler R

更新日期：1970-02-01 00:00:00

abstract：:Processing of dengue virus type 2 polyprotein precursor NS3-NS4A-NS4B-NS5 could be mediated by the catalytically active NS3 protease domain and NS2B in trans at the dibasic sites NS3-NS4A and NS4B-NS5. Subcellular localization of the unprocessed precursor NS3-NS4A-NS4B-NS5 showed that it was confined to a distinct sub...

journal_title：Journal of virology

authors： Zhang L,Mohan PM,Padmanabhan R

更新日期：1992-12-01 00:00:00

abstract：:PEPSCAN analysis has been used to characterize the immunogenic regions of the capsid protein (CP) in virions of plum pox potyvirus (PPV). In addition to the well-known highly immunogenic N- and C-terminal domains of CP, regions within the core domain of the protein have also shown high immunogenicity. Moreover, the N ...

journal_title：Journal of virology

authors： Fernández-Fernández MR,Martínez-Torrecuadrada JL,Roncal F,Domínguez E,García JA

更新日期：2002-12-01 00:00:00

abstract：:Mature dendritic cells (DCs) are potent antigen-presenting cells essential for initiating successful antiviral immune responses and would therefore serve as an ideal target for viruses seeking to evade or delay the immune response by disrupting their function. We have previously reported that VZV productively infects ...

journal_title：Journal of virology

authors： Morrow G,Slobedman B,Cunningham AL,Abendroth A

更新日期：2003-04-01 00:00:00

abstract：:Natural killer (NK) cells are components of the innate immunity and are key players in the defense against virus-infected and malignant cells. NK cells are particularly important in the innate defense against herpesviruses, including alphaherpesviruses. Aggravated and life-threatening alphaherpesvirus-induced disease ...

journal_title：Journal of virology

authors： De Pelsmaeker S,Dierick E,Klupp B,Mettenleiter TC,Cantoni C,Vitale M,Favoreel HW

更新日期：2019-03-21 00:00:00

abstract：:After incubation at 37 C for 2 or more days, Basal Medium Eagle (BME) supplemented with 25% fetal calf serum (FCS) was not able to support adequate growth of EB3 and other lines of Burkitt tumor cells. The medium did, however, increase, by a factor of about 10, the number of cells synthesizing herpes-type virus with w...

journal_title：Journal of virology

authors： Henle W,Henle G

更新日期：1968-03-01 00:00:00

abstract：:Hepatitis C virus (HCV) often causes a persistent infection associated with hypergammaglobulinemia, high levels of antiviral antibody and circulating immune complexes, and immune complex disease. We previously reported that only a limited neutralizing activity to vesicular stomatitis virus or HCV pseudotype is generat...

journal_title：Journal of virology

authors： Meyer K,Ait-Goughoulte M,Keck ZY,Foung S,Ray R

更新日期：2008-03-01 00:00:00

abstract：:Fanconi anemia (FA) patients have an increased risk for squamous cell carcinomas (SCCs) at sites of predilection for infection with high-risk human papillomavirus (HPV) types, including the oral cavity and the anogenital tract. We show here that activation of the FA pathway is a frequent event in cervical SCCs. We fou...

journal_title：Journal of virology

authors： Spardy N,Duensing A,Charles D,Haines N,Nakahara T,Lambert PF,Duensing S

更新日期：2007-12-01 00:00:00

abstract：:The Tax protein of human T-cell leukemia virus type 1 (HTLV-1) is a potent activator of viral transcription. Tax also activates the expression of specific cellular genes involved in the control of T-lymphocyte growth via effects on cellular transcription factors, including members of the NF-kappaB/cRel family. Immunoc...

journal_title：Journal of virology

authors： Bex F,McDowall A,Burny A,Gaynor R

更新日期：1997-05-01 00:00:00

abstract：:In intact Madin-Darby canine kidney (MDCK) cell monolayers, vesicular stomatitis virus (VSV) matures only at basolateral membranes beneath tight junctions, whereas influenza virus buds from apical cell surfaces. Early in the growth cycle, the viral glycoproteins are restricted to the membrane domain from which each vi...

journal_title：Journal of virology

authors： Roth MG,Compans RW

更新日期：1981-12-01 00:00:00

abstract：:The internal hydrophobic sequence within the flaviviral capsid protein (protein C) plays an important role in the assembly of infectious virions. Here, this sequence was analyzed in a West Nile virus lineage I isolate (crow V76/1). An infectious cDNA clone was constructed and used to introduce deletions into the inter...

journal_title：Journal of virology

authors： Schlick P,Taucher C,Schittl B,Tran JL,Kofler RM,Schueler W,von Gabain A,Meinke A,Mandl CW

更新日期：2009-06-01 00:00:00

abstract：:The molecular mechanisms responsible for random integration and gene targeting by recombinant adeno-associated virus (AAV) vectors are largely unknown, and whether vectors derived from autonomous parvoviruses transduce cells by similar pathways has not been investigated. In this report, we constructed vectors based on...

journal_title：Journal of virology

authors： Hendrie PC,Hirata RK,Russell DW

更新日期：2003-12-01 00:00:00

abstract：:Mitogenic activities of simian virus 40 large T and small t antigens were studied in serum-deprived human diploid fibroblasts. Wild-type large T and small t cooperated in stimulating DNA synthesis and in inducing hyperphosphorylation of the Rb gene product (pRb). In contrast, a T antigen mutant defective for pRb bindi...

journal_title：Journal of virology

authors： Ogryzko VV,Hirai TH,Shih CE,Howard BH

更新日期：1994-06-01 00:00:00

abstract：:Parvovirus capsids are assembled from multiple forms of a single protein and are quite stable structurally. However, in order to infect cells, conformational plasticity of the capsid is required and this likely involves the exposure of structures that are buried within the structural models. The presence of functional...

journal_title：Journal of virology

authors： Nelson CD,Minkkinen E,Bergkvist M,Hoelzer K,Fisher M,Bothner B,Parrish CR

更新日期：2008-11-01 00:00:00

abstract：:Latency-associated nuclear antigen 1 (LANA1) of Kaposi's sarcoma-associated herpesvirus (KSHV) is implicated in the persistence of the viral genome during latent infection. It has been suggested that LANA1 tethers the viral genome to the host chromosome and also participates actively in DNA replication from the termin...

journal_title：Journal of virology

authors： Lim C,Choi C,Choe J

更新日期：2004-07-01 00:00:00

abstract：:The Epstein-Barr virus (EBV)-induced membrane antigen (MA) was successfully solubilized from the membranes of viable EBV-infected Raji cells by treatment with papain (5 to 6 U per 1 X 10(7) to 2 X 10(7) cells). The loss of MA from viable cells was monitored by membrane immunofluorescence and antibody-dependent cellula...

journal_title：Journal of virology

authors： Pearson GR,Qualtiere LF

更新日期：1978-10-01 00:00:00

abstract：UNLABELLED:Barrier dysfunction of airway epithelium may increase the risk for acquiring secondary infections or allergen sensitization. Both rhinovirus (RV) and polyinosinic-polycytidilic acid [poly(I·C)], a double-stranded RNA (dsRNA) mimetic, cause airway epithelial barrier dysfunction, which is reactive oxygen speci...

journal_title：Journal of virology

authors： Unger BL,Ganesan S,Comstock AT,Faris AN,Hershenson MB,Sajjan US

更新日期：2014-04-01 00:00:00

abstract：:Since the number of human cases of infection with avian H5N1 influenza viruses is ever increasing, a pandemic outbreak caused by these viruses is feared. Therefore, in addition to virus-specific antibodies, there is considerable interest in immune correlates of protection against these viruses, which could be a target...

journal_title：Journal of virology

authors： Kreijtz JH,de Mutsert G,van Baalen CA,Fouchier RA,Osterhaus AD,Rimmelzwaan GF

更新日期：2008-06-01 00:00:00

abstract：:Previous studies with simian virus 40-transformed mouse 3T3 cells which are temperature sensitive for the expression of the transformed phenotype (ts SV3T3 cells) have shown that T-antigen expression and viral DNA transcription are under cell cycle control. Using these ts SV3T3 cells, we studied the expression of the ...

journal_title：Journal of virology

authors： Zouzias D,Basilico C

更新日期：1979-06-01 00:00:00

abstract：:The relative contributions of interleukin-12 (IL-12) and IL-23 to viral pathogenesis have not been extensively studied. IL-12p40 mRNA rapidly increases after neurotropic coronavirus infection. Infection of mice defective in both IL-12 and IL-23 (p40(-/-)), in IL-12 alone (p35(-/-)), and in IL-23 alone (p19(-/-)) revea...

journal_title：Journal of virology

authors： Kapil P,Atkinson R,Ramakrishna C,Cua DJ,Bergmann CC,Stohlman SA

更新日期：2009-06-01 00:00:00

abstract：:Influenza A viruses (IAVs) remain a significant public health threat, causing more than 300,000 hospitalizations in the United States during the 2015-2016 season alone. While only a few IAVs of avian origin have been associated with human infections, the ability of these viruses to cause zoonotic infections further in...

journal_title：Journal of virology

authors： Obadan AO,Santos J,Ferreri L,Thompson AJ,Carnaccini S,Geiger G,Gonzalez Reiche AS,Rajão DS,Paulson JC,Perez DR

更新日期：2019-03-05 00:00:00

abstract：:The adenovirus type 2 L1 region, which is located at 30.7 to 39.2 map units on the viral genome, is transcribed from the major late promoter during both early and late stages of virus replication, and a 52,000-Mr (52K) protein-55K protein doublet has been translated in vitro on L1-specific RNA. To investigate the bios...

journal_title：Journal of virology

authors： Lucher LA,Symington JS,Green M

更新日期：1986-03-01 00:00:00

abstract：:The human herpesvirus entry mediator C (HveC), also known as the poliovirus receptor-related protein 1 (PRR1) and as nectin-1, allows the entry of herpes simplex virus type 1 (HSV-1) and HSV-2 into mammalian cells. The interaction of virus envelope glycoprotein D (gD) with such a receptor is an essential step in the p...

journal_title：Journal of virology

authors： Krummenacher C,Baribaud I,Ponce de Leon M,Whitbeck JC,Lou H,Cohen GH,Eisenberg RJ

更新日期：2000-12-01 00:00:00

abstract：:An immunodominant envelope glycoprotein is encoded by the human herpesvirus 8 (HHV-8) (also termed Kaposi's sarcoma-associated herpesvirus) K8.1 gene. The functional role of glycoprotein K8.1 is unknown, and recognizable sequence homology to K8.1 is not detectable in the genomes of most other closely related gammaherp...

journal_title：Journal of virology

authors： Birkmann A,Mahr K,Ensser A,Yağuboğlu S,Titgemeyer F,Fleckenstein B,Neipel F

更新日期：2001-12-01 00:00:00

abstract：:The full-length viral RNA of human immunodeficiency virus type 1 (HIV-1) functions both as the mRNA for the viral structural proteins Gag and Gag/Pol and as the genomic RNA packaged within viral particles. The packaging signal which Gag recognizes to initiate genome encapsidation is in the 5' untranslated region (UTR)...

journal_title：Journal of virology

authors： Anderson EC,Lever AM

更新日期：2006-11-01 00:00:00

abstract：:To assess the possible contribution of host immune responses to the exertion of Fv2-associated resistance to Friend virus (FV)-induced disease development, we inoculated C57BL/6 (B6) mice that lacked various subsets of lymphocytes with FV containing no lactate dehydrogenase-elevating virus. Fv2(r) B6 mice lacking CD4(...

journal_title：Journal of virology

authors： Tsuji-Kawahara S,Kawabata H,Matsukuma H,Kinoshita S,Chikaishi T,Sakamoto M,Kawasaki Y,Miyazawa M

更新日期：2013-12-01 00:00:00

abstract：:Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has caused a pandemic of historic proportions and continues to spread globally, with enormous consequences to human health. Currently there is no vaccine, effective therapeutic, or prophylactic. As with other betacoronaviruses, attachment and entry o...

journal_title：Journal of virology

authors： Tandon R,Sharp JS,Zhang F,Pomin VH,Ashpole NM,Mitra D,McCandless MG,Jin W,Liu H,Sharma P,Linhardt RJ

更新日期：2021-01-13 00:00:00

abstract：:HIV-1's Rev protein forms a homo-oligomeric adaptor complex linking viral RNAs to the cellular CRM1/Ran-GTP nuclear export machinery through the activity of Rev's prototypical leucine-rich nuclear export signal (NES). In this study, we used a functional fluorescently tagged Rev fusion protein as a platform to study th...

journal_title：Journal of virology

authors： Behrens RT,Aligeti M,Pocock GM,Higgins CA,Sherer NM

更新日期：2017-01-18 00:00:00