Biosynthesis of the irregular monoterpene artemisia ketone, the sesquiterpene germacrene D and other isoprenoids in Tanacetum vulgare L. (Asteraceae).

Abstract:

:The incorporation of [1-13C]-labeled glucose into the irregular monoterpene artemisia ketone, the regular monoterpenes camphor and beta-thujone, the sesquiterpene germacrene D, the diterpene trans-phytol and beta-sitosterol and isofucosterol has been studied in axenic cultures of Tanacetum vulgare L. (Asteraceae). Quantitative 13C NMR spectroscopic analysis of the resulting labeling patterns showed that the isoprene units of the monoterpenes and the diterpene are formed via the methylerythritol phosphate (MEP) pathway, whereas the isoprene building blocks of the sesquiterpene and the sterols originate from the mevalonic acid (MVA) pathway.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Umlauf D,Zapp J,Becker H,Adam KP

doi

10.1016/j.phytochem.2004.08.019

subject

Has Abstract

pub_date

2004-09-01 00:00:00

pages

2463-70

issue

17

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(04)00396-6

journal_volume

65

pub_type

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