Abstract：
:The stem bark of Croton gratissimus (Euphorbiaceae) yielded four cembranolides, including the first reported example of a 2,12-cyclocembranolide, (+)-[1R*,2S*,7S*,8S*,12R*]-7,8-epoxy-2,12-cyclocembra-3E,10Z-dien-20,10-olide, whose structure was confirmed by means of single crystal X-ray analysis. This compound showed moderate activity against the PEO1 and PEO1TaxR ovarian cancer cell lines.
journal_name
Phytochemistryjournal_title
Phytochemistryauthors
Mulholland DA,Langat MK,Crouch NR,Coley HM,Mutambi EM,Nuzillard JMdoi
10.1016/j.phytochem.2010.05.014subject
Has Abstractpub_date
2010-08-01 00:00:00pages
1381-6issue
11-12eissn
0031-9422issn
1873-3700pii
S0031-9422(10)00208-6journal_volume
71pub_type
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