The pharmacokinetics and neuromuscular effects of rocuronium bromide in patients with liver disease.

abstract：UNLABELLED:Urethane is widely used as an anesthetic for animal studies because of its minimal effects on cardiovascular and respiratory systems and maintenance of spinal reflexes. Despite its usefulness in animal research, there are no reports concerning its molecular actions. We designed this study to determine whethe...

journal_title：Anesthesia and analgesia

authors： Hara K,Harris RA

更新日期：2002-02-01 00:00:00

abstract：UNLABELLED:Because perfluorocarbon (PFC) liquid contacts closely with the alveolar capillaries during partial liquid ventilation (PLV), PLV with cold PFC may be used for the induction of hypothermia. Twenty rabbits were randomized to PFC-induced hypothermia (PH) (n = 7; core temperature 35 degrees +/- 1 degrees C), sur...

journal_title：Anesthesia and analgesia

authors： Hong SB,Koh Y,Shim TS,Lee SD,Kim WS,Kim DS,Kim WD,Lim CM

更新日期：2002-01-01 00:00:00

abstract：:We studied the possible effects of repetitive (1-min interval) 50- and 100-Hz tetanic stimuli on 50-Hz and 100-Hz tetanic fade ratios (RF50HZ and RF100HZ). We also evaluated the sensitivity of the recorded responses to these two tests to assess residual neuromuscular block (isometric adductor pollicis mechanical activ...

journal_title：Anesthesia and analgesia

authors： Baurain MJ,Hoton F,Dernovoi BS,d'Hollander AA

更新日期：1996-01-01 00:00:00

abstract：UNLABELLED:In this study, we compared the direct myocardial depressant effects of sevoflurane, isoflurane, and halothane and determined whether an L-type Ca2+ channel agonist, Bay K 8644, could attenuate the myocardial depression induced by these anesthetics in cultured neonatal rat ventricular myocytes. Ventricular my...

journal_title：Anesthesia and analgesia

authors： Kanaya N,Kawana S,Tsuchida H,Miyamoto A,Ohshika H,Namiki A

更新日期：1998-11-01 00:00:00

abstract：:Patients receiving metoprolol before cardiac revascularization surgery were randomly divided into those in whom metoprolol was discontinued before the operation (N = 10) and those in whom metoprolol was continued up to the time of operation (N = 10). Cardiovascular responses to neuroleptanesthesia and sternotomy were ...

journal_title：Anesthesia and analgesia

authors： Pontén J,Häggendal J,Milocco I,Waldenström A

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:Pediatric chronic pain is very common and results in significant health care costs. Pediatric chronic pain is both an individual and a public health concern. The primary objective of this study was to generate a descriptive clinical profile of the patients referred to an anesthesiology-based pediatric chroni...

journal_title：Anesthesia and analgesia

authors： Vetter TR

更新日期：2008-03-01 00:00:00

abstract：:The epidural administration of morphine and fentanyl delay the regression of sensory anesthesia in postoperative patients receiving epidural bupivacaine. This study was performed to determine any differential effects of two lipid-soluble opioids upon regression of sensory anesthesia during coadministration with epidur...

journal_title：Anesthesia and analgesia

authors： Ferrante FM,Fanciullo GJ,Grichnik KP,Vaisman J,Sacks GM,Concepcion MA

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Intraoperative hypotension is common and associated with organ injury and death, although randomized data showing a causal relationship remain sparse. A risk-adjusted measure of intraoperative hypotension may therefore contribute to quality improvement efforts. METHODS:The measure we developed defines hypot...

journal_title：Anesthesia and analgesia

authors： Christensen AL,Jacobs E,Maheshwari K,Xing F,Zhao X,Simon SE,Domino KB,Posner KL,Stewart AF,Sanford JA,Sessler DI

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:Neuropathic pain is a result of a primary lesion or dysfunction of the peripheral or central nervous system, and its treatment is challenging. Animal models have been helpful in understanding mechanisms of neuropathic pain and in developing new treatment strategies. In this study, we examined the effect of p...

journal_title：Anesthesia and analgesia

authors： Ozsoylar O,Akçali D,Cizmeci P,Babacan A,Cahana A,Bolay H

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Volatile inhaled anesthetics exert a differential protective effect against bronchospasm development after cholinergic stimulation. However, their ability to inhibit the adverse respiratory consequences of an anaphylactic reaction after exposure to an allergen has not been characterized. We therefore compare...

journal_title：Anesthesia and analgesia

authors： Lele E,Petak F,Carnesecchi S,Virag K,Argiroffo CB,Habre W

更新日期：2013-06-01 00:00:00

abstract：:Adverse reactions to volatile anesthetics and depolarizing muscle relaxants can occur in patients with Duchenne muscular dystrophy (DMD) resulting in acute rhabdomyolysis and hyperkalemia. We report a case of hyperkalemic cardiac arrest after cardiac surgery using cardiopulmonary bypass in a child with unsuspected DMD...

journal_title：Anesthesia and analgesia

authors： Nathan A,Ganesh A,Godinez RI,Nicolson SC,Greeley WJ

更新日期：2005-03-01 00:00:00

abstract：:The purpose of this study was to evaluate the influence of the volume of methylene blue-local anesthetic on the spread of the injectate along the costal pleura. Twenty patients undergoing elective thoracotomy were studied. Twelve patients received intercostal nerve injection with 10 mL of 0.5% bupivacaine with methyle...

journal_title：Anesthesia and analgesia

authors： Moorthy SS,Dierdorf SF,Yaw PB

更新日期：1992-09-01 00:00:00

abstract：:The advantages of laparoscopic over open surgery have been documented in nonblinded settings. Our prospective, double-blind setting evaluated pain scores 72 h after surgery by comparing patients who underwent laparoscopic myomectomy or with laparotomy. Forty women referred for conservative myomectomy were included in ...

journal_title：Anesthesia and analgesia

authors： Holzer A,Jirecek ST,Illievich UM,Huber J,Wenzl RJ

更新日期：2006-05-01 00:00:00

abstract：:Cimetidine blunts the increase in cerebral blood flow (CBF) normally observed during hypoxia. It is important, therefore, to know whether other H2-blockers also affect the cerebral circulation adaptation to hypoxia. Cerebral blood flow was measured in 24 awake dogs after an intravenous injection of either saline (cont...

journal_title：Anesthesia and analgesia

authors： Audibert G,Saunier C,Hartemann D,Bigard O,Haberer JP

更新日期：1991-04-01 00:00:00

abstract：UNLABELLED:Opioid-abstinence hyperalgesia (OAH) is a phenomenon characterized by thermal and mechanical hyperalgesia that occurs between intermittent doses of opioids or after the chronic administration of these drugs when administration is abruptly stopped. In these studies we attempted to determine whether the activa...

journal_title：Anesthesia and analgesia

authors： Li X,Clark JD

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) patients are at increased risk for pulmonary and cardiovascular complications; perioperative mortality risk is unclear. This report analyzes cases submitted to the OSA Death and Near Miss Registry, focusing on factors associated with poor outcomes after an OSA-related event. We ...

journal_title：Anesthesia and analgesia

authors： Bolden N,Posner KL,Domino KB,Auckley D,Benumof JL,Herway ST,Hillman D,Mincer SL,Overdyk F,Samuels DJ,Warner LL,Weingarten TN,Chung F

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:During magnetic resonance imaging (MRI), children are at risk for body temperature variations. The cold MRI environment that preserves the MRI magnet can cause serious hypothermia. On the other hand, hyperthermia may also develop because of radiofrequency-induced heating of the tissues, particularly in pro...

journal_title：Anesthesia and analgesia

authors： Nasr VG,Schumann R,Bonney I,Diaz L,Ahmed I

更新日期：2012-06-01 00:00:00

abstract：UNLABELLED:Propofol has an antiemetic effect that may be mediated by gamma-aminobutyric acid (GABA) influences on the serotonin system, the mechanism of which is not known. We used three techniques, immunohistochemistry, High Performance Liquid Chromatography, and electrophysiology, to define propofol's effects on the ...

journal_title：Anesthesia and analgesia

authors： Cechetto DF,Diab T,Gibson CJ,Gelb AW

更新日期：2001-04-01 00:00:00

abstract：UNLABELLED:We performed this study to assess the influence of endotracheal tube (ETT) tip design (Murphy-tip versus Magill-tip) on nasal trauma during nasotracheal intubation with a conventional polyvinyl chloride ETT. Patients were randomly allocated to one of four groups (n = 25 each): Magill-tipped ETT and Murphy-ti...

journal_title：Anesthesia and analgesia

authors： Lee JH,Kim CH,Bahk JH,Park KS

更新日期：2005-10-01 00:00:00

abstract：:The primary outcome of this 8-year retrospective review was the failure of spinal anesthetic (SA) in elective hip and knee joint arthroplasty surgery. Of 3542 SAs, a total of 135 failures were identified (3.8%). Factors associated with increased odds of failure were younger age (odds ratio [OR], 1.03; 95% confidence i...

journal_title：Anesthesia and analgesia

authors： Colish J,Milne AD,Brousseau P,Uppal V

更新日期：2020-01-01 00:00:00

abstract：:The effects of epidural chloroprocaine with and without 1:200,000 epinephrine during labor and delivery on uterine activity, progress of labor, fetal heart rate, maternal blood pressure, newborn Apgar scores, neonatal acid-base status, and the Neurologic and Adaptive Capacity Scoring System (NACS) were compared in 28 ...

journal_title：Anesthesia and analgesia

authors： Abboud TK,DerSarkissian L,Terrasi J,Murakawa K,Zhu J,Longhitano M

更新日期：1987-01-01 00:00:00

abstract：:The tandem pore domain K channel family mediates background K currents present in excitable cells. Currents passed by certain members of the family are enhanced by volatile anesthetics, thus suggesting a novel mechanism of anesthesia. The newest member of the family, termed TRESK (TWIK [tandem pore domain weak inward ...

journal_title：Anesthesia and analgesia

authors： Liu C,Au JD,Zou HL,Cotten JF,Yost CS

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:The possibility that μ opioid agonists can influence cancer recurrence is a subject of recent interest. Epidemiologic studies suggested that there were differences in cancer recurrence in breast and prostate cancer contingent on anesthetic regimens. In this study, we identify a possible mechanism for these e...

journal_title：Anesthesia and analgesia

authors： Mathew B,Lennon FE,Siegler J,Mirzapoiazova T,Mambetsariev N,Sammani S,Gerhold LM,LaRiviere PJ,Chen CT,Garcia JG,Salgia R,Moss J,Singleton PA

更新日期：2011-03-01 00:00:00

abstract：:Rifampin is commonly used for the treatment of tuberculosis and staphylococcal infections, as well as for prevention of infection in cardiac valve and bone surgeries. We report a case of profound hypotension after anesthesia induction with propofol in a patient who was treated with two 600 mg doses of rifampin for pro...

journal_title：Anesthesia and analgesia

authors： Mirzakhani H,Nozari A,Ehrenfeld JM,Peterfreund R,Szabo M,Walsh JL,Jiang Y,Sandberg W,Rosow C,Wang J

更新日期：2013-07-01 00:00:00

abstract：:The rate of hydrolysis of chloroprocaine by human serum was studied in the presence and absence of a number of aminde local anesthetics and their metabolites. Bupivacaine (2.4 microgram/ml) and etidocaine (2.3 microgram/ml) caused 38% and 21% inhibition respectively of the rate of chloroprocaine hydrolysis. Circulatin...

journal_title：Anesthesia and analgesia

authors： Lalka D,Vicuna N,Burrow SR,Jones DJ,Ludden TM,Haegele KD,McNay JL

更新日期：1978-09-01 00:00:00

abstract：:Windup is a progressive increase in responses of nociceptive spinal cord neurons to repeated electrical C fiber stimulation. We hypothesized that isoflurane would depress windup at approximately the minimum alveolar anesthetic concentration (MAC) required to suppress purposeful movement in response to noxious stimulat...

journal_title：Anesthesia and analgesia

authors： Jinks SL,Antognini JF,Dutton RC,Carstens E,Eger EI 2nd

更新日期：2004-11-01 00:00:00

abstract：UNLABELLED:Several factors are responsible for hypercarbia during laparoscopic procedures. This study was undertaken because we observed a sudden increase in PaCO(2) in children with portal hypertension (PHT), which was unusual in healthy children undergoing laparoscopic procedures. Fifty-seven children underwent lapar...

journal_title：Anesthesia and analgesia

authors： Bozkurt P,Kaya G,Yeker Y,Sarimurat N,Yesildag E,Tekant G,Emir H,Senyuz OF

更新日期：2002-11-01 00:00:00

abstract：:We tested the hypothesis that middle ear pressure (MEP) is influenced by the choice of airway device during anesthesia with or without nitrous oxide (N2O) in the gas mixture. Eighty consecutive anesthetized, paralyzed ventilated patients (ASA physical status I-II, 18-65 yr) were randomly allocated for airway managemen...

journal_title：Anesthesia and analgesia

authors： Hohlrieder M,Keller C,Brimacombe J,Eschertzhuber S,Luckner G,Abraham I,von Goedecke A

更新日期：2006-01-01 00:00:00

abstract：:Alfentanil, a short-acting lipophilic opioid, is used for labor analgesia and cesarean section and may cause neonatal depression. However, direct placental alfentanil transfer has not been studied. We measured placental alfentanil transfer and uptake during in vitro perfusion. Placenta lobules from healthy parturients...

journal_title：Anesthesia and analgesia

authors： Zakowski MI,Ham AA,Grant GJ

更新日期：1994-12-01 00:00:00

abstract：:The aim of this study was to compare the efficacy and safety of ondansetron plus droperidol with each drug alone or placebo in the prevention of postoperative nausea and vomiting (PONV). One hundred females, aged 18-65 yr, ASA physical status I-II, undergoing general anesthesia for elective abdominal surgery were incl...

journal_title：Anesthesia and analgesia

authors： Pueyo FJ,Carrascosa F,Lopez L,Iribarren MJ,García-Pedrajas F,Saez A

更新日期：1996-07-01 00:00:00