C/EBP alpha expression in adipose tissue of genetically obese Zucker rats.

abstract：:Plasma membrane fractions from mouse livers were examined for the presence of growth regulatory peptides. Both growth inhibitory and growth stimulatory factors were found on these membranes. The growth inhibitory component could be enriched by extractions with both dimethylmaleic anhydride and octylglucoside. The grow...

journal_title：Biochemical and biophysical research communications

authors： Lieberman MA

更新日期：1984-05-16 00:00:00

abstract：:NAD+ is a co-enzyme in redox reactions and a substrate required for activity of various enzyme families, including sirtuins and poly(ADP-ribose) polymerases. Dietary supplementation of NAD+ precursors nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR) protects against metabolic disease, neurodegenerative ...

journal_title：Biochemical and biophysical research communications

authors： Fan R,Cui J,Ren F,Wang Q,Huang Y,Zhao B,Wei L,Qian X,Xiong X

更新日期：2018-06-02 00:00:00

abstract：:1alpha,25-Dihydroxyvitamin D3 (1alpha,25(OH)2D3) increases the binding of transforming growth factor beta1(TGF beta1) via TGF beta receptors to the surface of human osteoblasts. The increase in TGF beta receptors induced by 1alpha,25(OH)2D3 is dependent on increases in TGF beta secretion induced by 1alpha,25(OH)2D3, s...

journal_title：Biochemical and biophysical research communications

authors： Nagel D,Kumar R

更新日期：2002-02-08 00:00:00

abstract：:Based on pseudo amino acid (PseAA) composition and a novel hybrid feature selection frame, this paper presents a computational system to predict the PPIs (protein-protein interactions) using 8796 protein pairs. These pairs are coded by PseAA composition, resulting in 114 features. A hybrid feature selection system, mR...

journal_title：Biochemical and biophysical research communications

authors： Liu L,Cai Y,Lu W,Feng K,Peng C,Niu B

更新日期：2009-03-06 00:00:00

abstract：:Autophagy is the bulk degradation of cytosolic materials in lysosomes/vacuoles of eukaryotic cells. In the yeast Saccharomyces cerevisiae, 17 Atg proteins are known to be involved in autophagosome formation. Genome wide analyses have shown that Atg17 interacts with numerous proteins. Further studies on these interacti...

journal_title：Biochemical and biophysical research communications

authors： Kabeya Y,Kawamata T,Suzuki K,Ohsumi Y

更新日期：2007-05-04 00:00:00

abstract：:Glucocorticoids inhibit prostaglandin biosynthesis by inducing the formation of lipocortins. In human amnion cells dexamethasone elicited a concentration-dependent increase in prostaglandin production and raised intracellular lipocortin 1 concentrations. Dexamethasone could also potentiate the epidermal growth factor ...

journal_title：Biochemical and biophysical research communications

authors： Mitchell MD,Lytton FD,Varticovski L

更新日期：1988-02-29 00:00:00

abstract：:The 160 kDa alpha-mannosidase (E.C. 3.2.1.24) isolated from culture filtrate of Trichoderma reesei has wide aglycon specificity but cleaves the alpha1 --> 2 and alpha1 --> 3 mannosidic bonds with higher rate than alpha1 --> 6 bond and slowly hydrolyses yeast mannan and 1,6-alpha-mannan. The specific activity of the en...

journal_title：Biochemical and biophysical research communications

authors： Eneyskaya EV,Kulminskaya AA,Savel'ev AN,Shabalin KA,Golubev AM,Neustroev KN

更新日期：1998-04-07 00:00:00

abstract：:Calcium is a key signaling molecule and ion involved in a variety of diverse processes in our central nervous system (CNS) which include gene expression, synaptic transmission and plasticity, neuronal excitability and cell maintenance. Proper control of calcium signaling is not only vital for neuronal physiology but a...

journal_title：Biochemical and biophysical research communications

authors： Mark MD,Schwitalla JC,Groemmke M,Herlitze S

更新日期：2017-02-19 00:00:00

abstract：:The mRNA for the novel aldehyde dehydrogenase 5 (ALDH5) gene was detected in HuH7 hepatoma cells. The cells also expressed cytosolic aldehyde dehydrogenase (ALDH1) mRNA, but no mitochondrial aldehyde dehydrogenase (ALDH2) mRNA. Extracts of the hepatoma cells contained an enzymatic activity with an isoelectric point si...

journal_title：Biochemical and biophysical research communications

authors： Stewart MJ,Malek K,Xiao Q,Dipple KM,Crabb DW

更新日期：1995-06-06 00:00:00

abstract：:The acyclic nucleotide analogue (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine [(S)-HPMPA] is a potent and selective inhibitor of African swine fever virus (ASFV) replication. Using the DNA-DNA hybridization technique with plasmid pRPEL-2 as probe, we have shown that (S)-HPMPA exerts a specific, dose-dependent, in...

journal_title：Biochemical and biophysical research communications

authors： Arzuza O,García-Villalón D,Tabarés E,Gil-Fernández C,De Clercq E

更新日期：1988-07-15 00:00:00

abstract：:Here we investigate the effects of the dihydropyridine-type antagonists of calcium channels nitrendipine, nimodipine, nisoldipine and the calcium channel agonist BAY K 8644 on the induction of nitric oxide synthase (NOS) by bacterial endotoxin (lipopolysaccharide; LPS) in J774.2 macrophages cultured in vitro. Pretreat...

journal_title：Biochemical and biophysical research communications

authors： Szabó C,Thiemermann C,Vane JR

更新日期：1993-10-29 00:00:00

abstract：:The tumor necrosis factor (TNF) related apoptosis-inducing ligand (TRAIL or Apo2L) and its receptors are members of the tumor necrosis factor superfamily. TRAIL triggers apoptosis by binding to its two proapoptotic receptors DR4 and DR5, a process which is negatively regulated by binding of TRAIL to its two decoy rece...

journal_title：Biochemical and biophysical research communications

authors： Sun SY,Yue P,Zhou JY,Wang Y,Choi Kim HR,Lotan R,Wu GS

更新日期：2001-01-26 00:00:00

abstract：:Lung cancer causes high mortality without a declining trend and non small cell lung cancer represents 85% of all pulmonary carcinomas. MicroRNAs (miRNAs) serve as fine regulators of proliferation, migration, invasion/metastasis and angiogenesis of normal and cancer cells. Using TargetScan6.2, we predicted that the ubi...

journal_title：Biochemical and biophysical research communications

authors： Savita U,Karunagaran D

更新日期：2013-05-17 00:00:00

abstract：:Previous results from our laboratory showed that an increase in the nonpolar alkyl chain length in tetraalkylammonium cations is accompanied by greater efficiency in driving the B-to-Z transition. Analogous effects are observed when the hydrocarbon portion of carboxylate anions and alcohols is increased in size. The m...

journal_title：Biochemical and biophysical research communications

authors： McDonnell NB,Preisler RS

更新日期：1989-10-16 00:00:00

abstract：:Low-molecular-weight metabolites in human milk are gaining increasing interest in studies of infant nutrition. In the present study, the milk metabolome from a single mother was explored at different stages of lactation. Metabolites were extracted from sample aliquots using either methanol/water (MeOH/H2O) extraction ...

journal_title：Biochemical and biophysical research communications

authors： Wu J,Domellöf M,Zivkovic AM,Larsson G,Öhman A,Nording ML

更新日期：2016-01-15 00:00:00

abstract：:3-hydroxy-3-methylglutaryl-coenzyme A reductase (EC 1.1.1.3.4.) activity and cell membrane fluidity measured by fluorescence polarization using 1,6 diphenyl, 1,3,5-hexatriene as fluorescent probe have been concomitantly examined in HTC hepatoma cells, both in relation to growth rate and in response to treatment with h...

journal_title：Biochemical and biophysical research communications

authors： Richert L,Castagna M,Beck JP,Rong S,Luu B,Ourisson G

更新日期：1984-04-16 00:00:00

abstract：:RNA-binding proteins are believed to play important roles in regulation of neural functions. Recently, a mouse cDNA encoding the cold-inducible RNA-binding protein, Cirp, has been isolated, the amino acid sequence of which showed similarity to plant circadian rhythm proteins. In the present study, diurnal expression o...

journal_title：Biochemical and biophysical research communications

authors： Nishiyama H,Xue JH,Sato T,Fukuyama H,Mizuno N,Houtani T,Sugimoto T,Fujita J

更新日期：1998-04-17 00:00:00

abstract：:Ultraweak luminescence (uwCL) was coupled with electron spin resonance to study the reactions of 3 heterocyclic compounds (tryptophan, serotonin and imidazole) with peroxynitrite at pH 8.7. Tryptophan and serotonin reacted with emission of a flash peak of light (5 s) followed by a long-living light emission of +/- 80 ...

journal_title：Biochemical and biophysical research communications

authors： Mouithys-Mickalad A,Kohnen S,Deby C,Noels AF,Lamy M,Deby-Dupont G

更新日期：1999-06-07 00:00:00

abstract：:The PKC alpha, beta, delta, epsilon and zeta isoenzyme changes in the rat kidney cortex have been investigated after temporary occlusion of the renal artery, followed by reperfusion for up to 4 h. Increased PKC alpha, delta and epsilon immunoreactivity and PKC alpha activity occurred within 60 min of postischemic refl...

journal_title：Biochemical and biophysical research communications

authors： La Porta CA,Comolli R

更新日期：1993-03-31 00:00:00

abstract：:In this study terminal cisternae vesicles from rabbit skeletal muscle were fused into planar bilayers and the effect of calmodulin on single Ca2+ release channel currents was investigated. In the presence of 10(-7) and 10(-9) M free [Ca2+], nanomolar concentrations of calmodulin activated the channel by increasing the...

journal_title：Biochemical and biophysical research communications

authors： Buratti R,Prestipino G,Menegazzi P,Treves S,Zorzato F

更新日期：1995-08-24 00:00:00

abstract：:The interest in adiponutrin stems from adiponutrin variant I148M, which is strongly associated to non-alcoholic fatty liver disease. Adiponutrin has to date been considered to be solely an intracellular protein, with a role in lipid metabolism in liver and adipose tissue. However, a physiologically relevant role for a...

journal_title：Biochemical and biophysical research communications

authors： Winberg ME,Motlagh MK,Stenkula KG,Holm C,Jones HA

更新日期：2014-04-18 00:00:00

abstract：:Septic shock induced by lipopolysaccharide (LPS) is characterized by serious systemic inflammatory response and robust production of pro-inflammatory cytokines from activated macrophages. Damage-associated molecular patterns (DAMPs) secreted by activated macrophages are key contributors to septic shock. However, the c...

journal_title：Biochemical and biophysical research communications

authors： He Y,Peng Y,Tao L,Peng Z,Yang H

更新日期：2020-07-05 00:00:00

abstract：:We have previously demonstrated that the cyclin-dependent kinase inhibitor (Cki) Sic1 of Saccharomyces cerevisiae is phosphorylated in vitro by the CK2 kinase on Ser(201) residue. Moreover, we have collected evidence showing that Sic1 is functionally and structurally related to mammalian Cki p27(Kip1) and binds to the...

journal_title：Biochemical and biophysical research communications

authors： Barberis M,Pagano MA,Gioia LD,Marin O,Vanoni M,Pinna LA,Alberghina L

更新日期：2005-11-04 00:00:00

abstract：:Temperature is one of the primary environmental factors that affect aging, in which protein phosphorylation is an important regulator. Currently, the understanding of phosphorylation events in regulatory networks during aging has remained rather limited. Herein, the phosphoproteomes of C.elegans of different age group...

journal_title：Biochemical and biophysical research communications

authors： Huang J,Wu Z,Wang J,Zhang X

更新日期：2018-09-10 00:00:00

abstract：:Recently, two reports [R. E. Davis et al. (1997) Proc. Natl. Acad. Sci. USA 94, 4564-4569 and E. Fahy et al. (1997) Nucleic Acids Res. 25, 3102-3109] described a series of heteroplasmic mitochondrial DNA (mtDNA) mutations in the genes encoding two cytochrome c oxidase subunits (CO1 and CO2) which segregated in higher ...

journal_title：Biochemical and biophysical research communications

authors： Davis JN 2nd,Parker WD Jr

更新日期：1998-03-27 00:00:00

abstract：:This report examines the balance of positive and negative adipogenic factors in a line of immortalized 243 embryonic fibroblasts that undergo spontaneous preadipocyte differentiation. Control of adipogenesis reflects the interplay of factors that promote or inhibit expression of C/EBPalpha and PPARgamma. The 243 cells...

journal_title：Biochemical and biophysical research communications

authors： Bennett CN,Hodge CL,MacDougald OA,Schwartz J

更新日期：2003-02-28 00:00:00

abstract：:Rice, a monocot model crop, contains at least 48 putative E2 ubiquitin (Ub)-conjugating enzymes. Based on homology comparisons with 40 Arabidopsis E2 proteins and 35 human E2s, 48 rice E2s were classified into 15 different groups. Yeast two-hybrid analyses using the U-box-domain regions of armadillo (ARM)-U-box E3 Ub-...

journal_title：Biochemical and biophysical research communications

authors： Bae H,Kim WT

更新日期：2014-02-21 00:00:00

abstract：:Insulin-like growth factor binding protein (IGFBP) gene expression and IGFBP secretion were investigated in a retinoic acid (RA)-resistant subline (RROI) of MCF-7 human breast carcinoma cells. Our results demonstrate that RRO-I cells constitutively secrete higher levels of IGFBP-3 and IGFBP-5. In addition, we found th...

journal_title：Biochemical and biophysical research communications

authors： Sheikh MS,Shao ZM,Chen JC,Clemmons DR,Roberts CT Jr,LeRoith D,Fontana JA

更新日期：1992-11-16 00:00:00

abstract：:p73 is one of the p53 family members which are transcription factors involved in the regulation of cell proliferation, apoptosis, and differentiation. In this study, we cloned the p73 cDNA from zebrafish ovary RNA. The consensus open reading frame (1923bp) encodes a polypeptide of 640 amino acids which shares 70-95% i...

journal_title：Biochemical and biophysical research communications

authors： Pan H,Dung HN,Hsu HM,Hsiao KM,Chen LY

更新日期：2003-07-25 00:00:00

abstract：:The vitamin D pathway is related to the mass and function of skeletal muscles. Several studies have demonstrated the role of vitamin D receptor (VDR) and CYP27B1 in skeletal muscles, suggesting that these proteins may regulate skeletal muscles and their function. However, it remains unclear whether the expression of V...

journal_title：Biochemical and biophysical research communications

authors： Mori R,Yokokawa T,Fujita S

更新日期：2020-08-27 00:00:00