Abstract:
:To assess binocular interactions and possible ocular dominance in entrainment of circadian rhythms, Syrian hamsters maintained in LL were subjected for several weeks to schedules of eye occlusion with opaque contact lenses. In separate groups, the opaque lens was inserted into the left or right eye for 12 h at the same clock time each day. The left and right eyes of other groups were alternately occluded for 12 h each day, with initial occlusion of either the left or right eye for different groups. A majority of hamsters entrained their locomotor activity rhythm when 1 eye was occluded for 12 h. The modified visual input imposed by covering 1 eye is sufficient to induce entrainment. Locomotor rhythms of most animals in which the 2 eyes were alternately occluded for 12 h each day phasedelayed onset of activity during the 1st few days of the lensing procedure; activity onset then free ran with tau < 24 h for several weeks until entraining with tau of 24 h regardless of whether the left or right eye was initially occluded. Entrainment eventually occurred when activity onset coincided with occlusion of the eye contralateral to the one that was first lensed. Photic and nonphotic explanations for eventual entrainment of locomotor rhythms are discussed, and evidence for asymmetrical photic input from the 2 eyes to the SCN is considered.
journal_name
J Biol Rhythmsjournal_title
Journal of biological rhythmsauthors
Park JH,Paul MJ,Butler MP,Zucker Idoi
10.1177/0748730404272967subject
Has Abstractpub_date
2005-02-01 00:00:00pages
49-59issue
1eissn
0748-7304issn
1552-4531pii
20/1/49journal_volume
20pub_type
杂志文章abstract::Many mammalian cell types show daily rhythms in gene expression driven by a circadian pacemaker. For example, cultured astrocytes display circadian rhythms in Period1 and Period2 expression. It is not known, however, how or which intercellular factors synchronize and sustain rhythmicity in astrocytes. Because astrocyt...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730409332042
更新日期:2009-04-01 00:00:00
abstract::A rhythm mutant of Drosophila melanogaster was induced by chemical mutagenesis and isolated by testing for locomotor activity rhythms, which in the new variant had periods of approximately 16 hr. The sex-linked mutation responsible for this ultrashort period causes 20-hr rhythms when heterozygous with a normal X. This...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873049400900303
更新日期:1994-01-01 00:00:00
abstract::The circadian pacemaker of the SCN is a heterogeneous structure containing many single-cell oscillators that display phase differences in gene expression and electrical activity rhythms. Thus far, it is unknown how single neurons contribute to the population signal measured from the SCN. The authors used single-unit e...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730406290317
更新日期:2006-08-01 00:00:00
abstract::How the cellular elements of the SCN are synchronized to each other is not well understood. We explore circadian oscillations manifest at the level of the cell, the tissue, and the whole animal to better understand intra-SCN synchrony and master clock function of the nucleus. At each level of analysis, responses to va...
journal_title:Journal of biological rhythms
pub_type: 杂志文章,评审
doi:10.1177/0748730409344800
更新日期:2009-10-01 00:00:00
abstract::While the rapid development of personal computers and high-throughput recording systems for circadian rhythms allow chronobiologists to produce huge amounts of data, the software to analyze them often lags behind. Here, we announce newly developed chronobiology software that is easy to use, compatible with many differ...
journal_title:Journal of biological rhythms
pub_type: 信件
doi:10.1177/0748730411414264
更新日期:2011-10-01 00:00:00
abstract::The circadian rhythm of eclosion activity and its pacemaker were analyzed in a series of latitudinal races of Drosophila auraria ranging from 34.2 degrees to 42.9 degrees N in Japan. The phase of the rhythm (psi EL) to the daily photoperiod (PP) changes as daylength is increased, and the slope of psi EL (PP) changes w...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:
更新日期:1989-07-01 00:00:00
abstract::A role for nitric oxide in circadian responses to light has been indicated in previous studies. To determine the specific function of NO-, the authors manipulated NO- and nitric oxide synthase (NOS) activity prior to light pulses that would normally induce phase shifts. The NOS inhibitor, L-NAME, selectively attenuate...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873049701200404
更新日期:1997-08-01 00:00:00
abstract::The hypothalamic suprachiasmatic nucleus (SCN), a circadian pacemaker, is present in all mammalian brains. It has a complex organization of peptide-containing neurons that is similar among species, but calcium-binding proteins are expressed variably. Neurons containing calretinin have been described in the SCN in a nu...
journal_title:Journal of biological rhythms
pub_type: 信件
doi:10.1177/0748730416654024
更新日期:2016-08-01 00:00:00
abstract::The circadian system in higher organisms temporally orchestrates rhythmic changes in a vast number of genes and gene products in different organs. Complex interactions between these components, both within and among cells, ultimately lead to rhythmic behavior and physiology. Identifying the plethora of circadian targe...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730406294767
更新日期:2006-12-01 00:00:00
abstract::House sparrows (Passer domesticus) whose circadian rhythms of locomotor activity and feeding had been abolished by pinealectomy were held in constant dim light and periodically exposed to melatonin in the drinking water. By alternating 8 h of melatonin water with variable phases of tap water, rhythms with periods (T) ...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873049501000305
更新日期:1995-09-01 00:00:00
abstract::Most visual system functions, such as opsin gene expression, retinal neural transmission, light perception, and visual sensitivity, display robust day-night rhythms. The rhythms persist in constant lighting conditions, suggesting the involvement of endogenous circadian clocks. While the circadian pacemakers that contr...
journal_title:Journal of biological rhythms
pub_type: 杂志文章,评审
doi:10.1177/0748730419863917
更新日期:2019-10-01 00:00:00
abstract::Entrainability of the circadian rhythm of mosquito flight and locomotor activity was investigated by giving a 24-hr temperature cycle (28 degrees C for 16 hr, 23 degrees C for 8 hr) to the free-running rhythm or by shifting the temperature cycle. The phase angle difference between the entrained rhythm and the temperat...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873049300800304
更新日期:1993-10-01 00:00:00
abstract::The frequency demultiplication hypothesis (FDH) posits that circannual rhythms are generated from circadian cycles by frequency transformation to the lower-frequency rhythm. To test the FDH, we determined the periods of the circannual body mass and estrous cycles of golden-mantled ground squirrels with circadian locom...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873048600100402
更新日期:1986-01-01 00:00:00
abstract::Since the advent of techniques to investigate gene expression on a large scale, numerous circadian rhythms in mRNA amount have been reported. These rhythms generally differ in amplitude and phase. The authors investigated how far a parameter not regulated by the circadian clock can influence the phase of a rhythm in R...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730408325753
更新日期:2008-12-01 00:00:00
abstract::The hematologic system performs a number of essential functions, including oxygen transport, the execution of the immune response against tumor cells and invading pathogens, and hemostasis (blood clotting). These roles are performed by erythrocytes (red blood cells), leukocytes (white blood cells), and thrombocytes (p...
journal_title:Journal of biological rhythms
pub_type: 杂志文章,评审
doi:10.1177/0748730415592729
更新日期:2015-10-01 00:00:00
abstract::Transplantation of the fetal suprachiasmatic nucleus (SCN) in arrhythmic SCN-lesioned rats can reinstate circadian drinking rhythms in 40% to 50% of the cases. In the current article, it was investigated whether the failure in the other rats could be due to the absence of a circadian rhythm in the grafted SCN, using a...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873099129000416
更新日期:1999-02-01 00:00:00
abstract::Austrovenus stutchburyi is an intertidal, burrowing, filter-feeding bivalve. It exhibits a strong, approximately tidal pattern in the time of gaping of its valves when in constant laboratory conditions. Individuals that have been held in laboratory conditions long enough to lose their overt gaping pattern will respond...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873049701200208
更新日期:1997-04-01 00:00:00
abstract::The authors sought to investigate the role of phytochromes A and B (phyA and phyB) and cryptochromes 1 and 2 (cryl and cry2) in the synchronization of the leaf position rhythm in Arabidopsis thaliana. The seedlings were transferred from white light-dark cycles to free-running conditions with or without exposure to a l...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873001129002213
更新日期:2001-12-01 00:00:00
abstract::Testicular growth was monitored in male ferrets subjected to one of the following photoperiodic treatments begun at weaning (8 weeks of age): 8 hr light/day (short days), 18 hr light/day (long days), or short days followed by transition to long days at either 10, 12, or 14 weeks of age. Mean ages to achieve adult test...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873049000500301
更新日期:1990-10-01 00:00:00
abstract::The mammalian circadian pacemaker is located in the suprachiasmatic nucleus (SCN). Various inputs modulate pacemaker phase, including the serotonergic (5HTergic) input from the midbrain raphe. 5HT phase-advances the SCN pacemaker when applied during mid subjective day. In vitro studies indicate that 5HT advances the m...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873002129002429
更新日期:2002-04-01 00:00:00
abstract::In vertebrates, reproductive output often increases with age. Unlike older birds, first-year photoperiodic birds lack experience with the reproductively stimulatory effects of long day lengths (photostimulation). We examined whether age-related differences in annual reproductive development could be partially attribut...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730412468087
更新日期:2013-02-01 00:00:00
abstract::Although pineal "synaptic" ribbons (SR) are frequently examined by means of quantitative electron microscopy, their functional significance remains unclear. The same is true for related structures--"synaptic" spherules (SPH). In the course of such studies, it has been noted that SR counts may differ from laboratory to...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873048800300103
更新日期:1988-04-01 00:00:00
abstract::Obesity during pregnancy causes numerous maternal and fetal health complications, but the underlying mechanisms remain unclear. Adipose tissue dysfunction in obesity has previously been linked to disruption of the intrinsic adipose clock gene network that is crucial for normal metabolic function. This adipose clock al...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730418772499
更新日期:2018-06-01 00:00:00
abstract::Various aspects of mammalian endocrine physiology show a time-of-day variation with a period of 24 h, which represents an adaptation to the daily environmental fluctuations resulting from the rotation of the earth. These 24-h rhythms in hormone abundance and consequently hormone function may rely on rhythmic signals p...
journal_title:Journal of biological rhythms
pub_type: 杂志文章,评审
doi:10.1177/0748730415580881
更新日期:2015-08-01 00:00:00
abstract::We have recently shown that molecular rhythms in the murine suprachiasmatic nucleus (SCN) are affected by repeated social defeat (SD) during the dark/active phase (social defeat dark [SDD]), while repeated SD during the light/inactive phase (social defeat light [SDL]) had no influence on PERIOD2::LUCIFERASE explant rh...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730415576192
更新日期:2015-06-01 00:00:00
abstract::Drosophila littoralis is a latitudinally widespread European species of the Drosophila virilis group. The species has ample genetic variation in photoperiodism (adult diapause) and circadian rhythmicity (pupal eclosion rhythm), with adaptive latitudinal clines in both of them. The possible common genetic basis between...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730405283418
更新日期:2006-02-01 00:00:00
abstract::We investigated the extent to which photoperiodic fluctuations synchronize annual thyroid and gonadal rhythmicity in edible dormice. The effects of different daylength manipulations (LD 4:20, LD 6:18, LD 18:6, LD 20:4) were examined during the two critical ascending and regressive phases of the annual plasma testoster...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873049100600405
更新日期:1991-01-01 00:00:00
abstract::During the first 7 weeks of postnatal life, short day lengths inhibit the onset of puberty in many photoperiodic rodents, but not in Syrian hamsters. In this species, timing of puberty and fecundity are independent of the early postnatal photoperiod. Gestational day length affects postnatal reproductive development in...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730408322985
更新日期:2008-10-01 00:00:00
abstract::In isolated slices of hypothalamus, suprachiasmatic nucleus (SCN) neurons were recorded intracellularly. Blockade of Ca++ channels increased spike duration, eliminating an early component of the afterhyperpolarization (AHP) that followed evoked spikes. The duration and reversal potential of AHPs were, however, unaffec...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873049000500106
更新日期:1990-04-01 00:00:00
abstract::Using quantitative autoradiography, 2-(125)I-melatonin binding was investigated throughout the light:dark cycle in the suprachiasmatic nuclei (SCN), paraventricular nuclei (PVT), and pars tuberalis (PT) of adult female Siberian hamsters kept for 10 weeks in either long or short photoperiods (LP or SP, respectively). P...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873049601100406
更新日期:1996-12-01 00:00:00