Abstract:
:While the rapid development of personal computers and high-throughput recording systems for circadian rhythms allow chronobiologists to produce huge amounts of data, the software to analyze them often lags behind. Here, we announce newly developed chronobiology software that is easy to use, compatible with many different systems, and freely available. Our system can perform the most frequently used analyses: actogram drawing, periodogram analysis, and waveform analysis. The software is distributed as a pure Java plug-in for ImageJ and so works on the 3 main operating systems: Linux, Macintosh, and Windows. We believe that this free software raises the speed of data analyses and makes studying chronobiology accessible to newcomers.
journal_name
J Biol Rhythmsjournal_title
Journal of biological rhythmsauthors
Schmid B,Helfrich-Förster C,Yoshii Tdoi
10.1177/0748730411414264subject
Has Abstractpub_date
2011-10-01 00:00:00pages
464-7issue
5eissn
0748-7304issn
1552-4531pii
26/5/464journal_volume
26pub_type
信件abstract::Threads of evidence from recent experimentation in retinal morphology, neurochemistry, electrophysiology, and visual perception point toward rhythmic ocular processes that may be integral components of circadian entrainment in mammals. Components of retinal cell biology (rod outer-segment disk shedding, inner-segment ...
journal_title:Journal of biological rhythms
pub_type: 杂志文章,评审
doi:10.1177/074873049100600104
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abstract::Almost exclusively, photoperiodic insects respond to a given photoperiod in one of two ways: a "long-day" response or a "short-day" response. Intermediate responses occur only at a very restricted range of photoperiods (often less than 30 min) and are generally population phenomena rather than intermediate responses o...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873049300800104
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abstract::Past research has shown that there is a circadian oscillator in laboratory rats that is entrained by restricted feeding schedules. However, in laboratory rats at least, the light-dark (LD) cycle is the dominant zeitgeber in the entrainment of wheel-running activity rhythms. Given that dasyurid marsupials are predomina...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
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abstract::Previous research has demonstrated a clear link between late chronotype and depression. The vulnerability factors underpinning this link, however, are unclear. Here the relationship between two specific emotion regulation strategies, cognitive reappraisal and expressive suppression, and chronotype was investigated usi...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730417709111
更新日期:2017-08-01 00:00:00
abstract::The authors have shown previously that vasopressin (VP) release from suprachiasmatic nucleus (SCN) efferents in rats is important for the timing of the circadian activity of the hypothalamo-pituitary-adrenal (HPA) axis, resulting in a circadian rise in corticosterone at dusk. When meals are supplied at a fixed time du...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873098128999880
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abstract::Siberian hamsters are photoperiodic seasonally breeding rodents. To date, there has been no evidence that Siberian hamsters exhibit an annual rhythm in reproductive, thermoregulatory, molt, or body mass changes. However, given that the termination of their winter cycle is under endogenous control, the authors thought ...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873040001500206
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abstract::The measurement of circulating levels of brain-derived neurotrophic factor (BDNF) has been proposed to be a marker of disease and an indicator of recovery. Thus, knowing the temporal pattern and influence of potential circadian rhythms is important. Although several studies have measured BDNF at different times of day...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730417693124
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abstract::Seasonal changes in numerous aspects of mammalian immune function arise as a result of the annual variation in environmental day length (photoperiod), but it is not known if absolute photoperiod or relative change in photoperiod drives these changes. This experiment tested the hypothesis that an individual's history o...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730409349714
更新日期:2009-12-01 00:00:00
abstract::How the cellular elements of the SCN are synchronized to each other is not well understood. We explore circadian oscillations manifest at the level of the cell, the tissue, and the whole animal to better understand intra-SCN synchrony and master clock function of the nucleus. At each level of analysis, responses to va...
journal_title:Journal of biological rhythms
pub_type: 杂志文章,评审
doi:10.1177/0748730409344800
更新日期:2009-10-01 00:00:00
abstract::Melatonin is secreted systemically from the pineal gland maximally at night but is also produced locally in many tissues. Its chronobiological function is mainly exerted by pineal melatonin. It is a feedback regulator of the main circadian pacemaker in the hypothalamic suprachiasmatic nuclei and of many peripheral osc...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730415616678
更新日期:2016-02-01 00:00:00
abstract::We have recently shown that molecular rhythms in the murine suprachiasmatic nucleus (SCN) are affected by repeated social defeat (SD) during the dark/active phase (social defeat dark [SDD]), while repeated SD during the light/inactive phase (social defeat light [SDL]) had no influence on PERIOD2::LUCIFERASE explant rh...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730415576192
更新日期:2015-06-01 00:00:00
abstract::Using quantitative autoradiography, 2-(125)I-melatonin binding was investigated throughout the light:dark cycle in the suprachiasmatic nuclei (SCN), paraventricular nuclei (PVT), and pars tuberalis (PT) of adult female Siberian hamsters kept for 10 weeks in either long or short photoperiods (LP or SP, respectively). P...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/074873049601100406
更新日期:1996-12-01 00:00:00
abstract::The mammalian circadian clock is known to be entrained by both a daily light-dark cycle and daily feeding cycle. However, the mechanisms of feeding-induced entrainment are not as fully understood as those of light entrainment. To elucidate the first step of entrainment of the liver clock, we identified the circadian c...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730411405958
更新日期:2011-06-01 00:00:00
abstract::An intricate transcription-translation feedback loop (TTFL) governs cellular circadian rhythms in mammals. Here, we report that the zinc finger transcription factor Krüppel-like factor 9 (KLF9) is regulated by this TTFL, it associates in chromatin at the core circadian clock and clock-output genes, and it acts to modu...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730420913205
更新日期:2020-06-01 00:00:00
abstract::A 24-h treatment with the cytokine tumor necrosis factor-alpha (TNF-alpha) suppresses transcription of E-box-driven clock genes (D-site albumin promoter binding protein, Dbp; Tyrotroph embryonic factor, Tef ; Hepatic leukemia factor, Hlf; Period homolog to Drosophila 1/2/3, Per1, Per2, and Per3) by yet unknown molecul...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730409336579
更新日期:2009-08-01 00:00:00
abstract::The circadian system in higher organisms temporally orchestrates rhythmic changes in a vast number of genes and gene products in different organs. Complex interactions between these components, both within and among cells, ultimately lead to rhythmic behavior and physiology. Identifying the plethora of circadian targe...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730406294767
更新日期:2006-12-01 00:00:00
abstract::A recent report that popliteal illumination shifted the circadian rhythms of body temperature and melatonin challenged the longstanding belief that light phase-shifting the circadian system in mammals is mediated only through the retina. The authors tested effects of popliteal illumination and illumination provided th...
journal_title:Journal of biological rhythms
pub_type: 临床试验,杂志文章
doi:10.1177/074873040001500307
更新日期:2000-06-01 00:00:00
abstract::The circadian timing system has three principal elements: the retina, the intergeniculate leaflet (IGL) of the thalamus, and the suprachiasmatic nucleus (SCN). Since the human circadian timing system cannot be studied experimentally, we have used another primate, the macaque monkey, to help provide insight into the or...
journal_title:Journal of biological rhythms
pub_type: 杂志文章,评审
doi:
更新日期:1993-01-01 00:00:00
abstract::Various aspects of mammalian endocrine physiology show a time-of-day variation with a period of 24 h, which represents an adaptation to the daily environmental fluctuations resulting from the rotation of the earth. These 24-h rhythms in hormone abundance and consequently hormone function may rely on rhythmic signals p...
journal_title:Journal of biological rhythms
pub_type: 杂志文章,评审
doi:10.1177/0748730415580881
更新日期:2015-08-01 00:00:00
abstract::The daily biological clock regulates the timing of sleep and physiological processes that are of fundamental importance to human health, performance, and well-being. Environmental parameters of relevance to biological clocks include (1) daily fluctuations in light intensity and temperature, and (2) seasonal changes in...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
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更新日期:2008-08-01 00:00:00
abstract::Honey bee workers care for ("nurse") the brood around the clock without circadian rhythmicity, but then they forage outside with strong circadian rhythms and a consolidated nightly rest. This chronobiological plasticity is associated with variation in the expression of the canonical "clock genes" that regulate the cir...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730411431404
更新日期:2012-02-01 00:00:00
abstract::Circadian clocks drive daily rhythms of physiology and behavior in multiple organisms and synchronize these rhythms to environmental cycles of light and temperature. The basic mechanism of the clock consists of a transcription-translation feedback loop, in which key clock proteins negatively regulate their own transcr...
journal_title:Journal of biological rhythms
pub_type: 杂志文章,评审
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abstract::Aging alters numerous aspects of circadian biology, including the amplitude of rhythms generated by the suprachiasmatic nuclei (SCN) of the hypothalamus, the site of the central circadian pacemaker in mammals, and the response of the pacemaker to environmental stimuli such as light. Although previous studies have desc...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
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更新日期:2003-04-01 00:00:00
abstract::The tau mutation in Syrian hamsters (Mesocricetus auratus) is phenotypically expressed in a period of the circadian rhythm of about 20 h in homozygotes (SS) and about 22 h in heterozygotes (S+). The authors investigate whether this well-defined model for variation in circadian period exhibits associated changes in ene...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
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更新日期:1997-10-01 00:00:00
abstract::Mice with targeted gene disruption have provided important information about the molecular mechanisms of circadian clock function. A full understanding of the roles of circadian-relevant genes requires manipulation of their expression in a tissue-specific manner, ideally including manipulation with high efficiency wit...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730418757006
更新日期:2018-04-01 00:00:00
abstract::A gradual adaptation to a shifted light-dark (LD) cycle is a key element of the circadian clock system and believed to be controlled by the central circadian pacemaker, the suprachiasmatic nucleus (SCN). Endocrine factors have a strong influence on the regulation of the circadian clock network and alter acute photic r...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
doi:10.1177/0748730420965291
更新日期:2020-12-01 00:00:00
abstract::Systematic treatment of hamsters with triazolam (TRZ) or novel wheel (NW) access will yield PRCs similar to those for neuropeptide Y. Both TRZ and NW access require an intact intergeniculate leaflet (IGL) to modulate circadian rhythm phase. It is commonly suggested that both stimulus types influence rhythm phase respo...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
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更新日期:1998-12-01 00:00:00
abstract::Abstract The cyanobacterial clock protein KaiC regulates the circadian cycle by exhibiting rhythms in transcription, translation, and phosphorylation. KaiC phosphorylation persists in circadian cycling even under transcription-less conditions and was reconstituted in vitro by incubating KaiC, KaiA, and KaiB. This pres...
journal_title:Journal of biological rhythms
pub_type: 杂志文章
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abstract::Most cyclic biological processes are under control of a circadian molecular timing system that synchronizes these phenomena to the 24-h day. One generic property of circadian-controlled processes is that they operate within a specific temperature range, below which the manifestation of rhythm ceases. Little is known a...
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pub_type: 杂志文章
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abstract::Intertidal species have both circadian and circatidal clocks. Although the behavioral evidence for these oscillators is more than 5 decades old, virtually nothing is known about their molecular clockwork. Pigment-dispersing hormones (PDHs) were originally described in crustaceans. Their insect homologs, pigment-disper...
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pub_type: 杂志文章
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更新日期:2011-12-01 00:00:00