Characterization of a novel influenza A virus hemagglutinin subtype (H16) obtained from black-headed gulls.

abstract：:Adeno-associated virus type 5 (AAV5) has a linear, single-stranded DNA genome of ca. 5 kb and an overlapping transcription profile featuring multiple promoters and a single intron in the center of the genome. Unlike the situation for the prototype AAV2, AAV5 RNAs transcribed from upstream promoters at map units 7 (P7)...

journal_title：Journal of virology

authors： Qiu J,Nayak R,Pintel DJ

更新日期：2004-01-01 00:00:00

abstract：:It is possible to oxidize in situ the 3'-terminals of the double-stranded ribonucleic acid (RNA) contained in structurally intact cytoplasmic polyhedrosis virus. The number of 3'-terminals subsequently found by reduction with tritiated sodium borohydride was equivalent to the number observed in RNA first isolated from...

journal_title：Journal of virology

authors： Lewandowski LJ,Millward S

更新日期：1971-04-01 00:00:00

abstract：:RNA recombination occurs frequently during replication of tombusviruses and carmoviruses, which are related small plus-sense RNA viruses of plants. The most common recombinants generated by these viruses are either defective interfering (DI) RNAs or chimeric satellite RNAs, which are thought to be generated by templat...

journal_title：Journal of virology

authors： Cheng CP,Nagy PD

更新日期：2003-11-01 00:00:00

abstract：:Vaccines preventing HIV-1 infection will likely elicit antibodies that neutralize diverse strains. However, the capacity for lentiviruses to escape broadly neutralizing antibodies (NAbs) is not completely understood, nor is it known whether NAbs alone can control heterologous infection. Here, we determined that conval...

journal_title：Journal of virology

authors： Taylor SD,Leib SR,Carpenter S,Mealey RH

更新日期：2010-07-01 00:00:00

abstract：:The rat-derived Harvey murine sarcoma virus (Ha-MuSV) contains a transduced ras oncogene activated by two missense mutations and flanked by rat retroviruslike VL30 sequences. Ha-MuSV induces focal transformation of mouse NIH 3T3 cells in vitro and tumors (fibrosarcomas and splenic erythroleukemias) in newborn mice. We...

journal_title：Journal of virology

authors： Velu TJ,Vass WC,Lowy DR,Tambourin PE

更新日期：1989-03-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) infection requires cell surface expression of CD4. Costimulation of CD8(+)/CD4(-) T lymphocytes by anti-CD3 and anti-CD28 antibodies or by allogeneic dendritic cells induced expression of CD4 and rendered these CD8 cells susceptible to HIV-1 infection. Naive CD45RA+ cells re...

journal_title：Journal of virology

authors： Kitchen SG,Korin YD,Roth MD,Landay A,Zack JA

更新日期：1998-11-01 00:00:00

abstract：:Interferons inhibit the replication of vesicular stomatitis virus (VSV), but not of encephalomyocarditis virus (EMCV), in mouse JLSV-11 cells. We report the isolation of clonal derivatives from this cell line in which the replication of both viruses is impaired by interferons. These clones were selected from the paren...

journal_title：Journal of virology

authors： Kumar R,Choubey D,Lengyel P,Sen GC

更新日期：1988-09-01 00:00:00

abstract：:The mammalian APOBEC3 proteins are an important component of the cellular innate immune response to retroviral infection. APOBEC3G can extinguish HIV-1 infectivity by its incorporation into virus particles and subsequent cytosine deaminase activity that attacks the nascent viral cDNA during reverse transcription, caus...

journal_title：Journal of virology

authors： Sadler HA,Stenglein MD,Harris RS,Mansky LM

更新日期：2010-07-01 00:00:00

abstract：:Human immunodeficiency virus type 2 (HIV-2) strains vary widely in their abilities to grow in Old World monkey (OWM) cells such as those of cynomolgus monkeys (CM). We evaluated eight HIV-2 isolates for their sensitivities to CM TRIM5alpha, an anti-HIV factor in OWM cells. We found that different HIV-2 isolates showed...

journal_title：Journal of virology

authors： Song H,Nakayama EE,Yokoyama M,Sato H,Levy JA,Shioda T

更新日期：2007-07-01 00:00:00

abstract：:Embryonic stem cells are subjected to a dynamic genome regulation during development. Here we report that the ectopic lentiviral transgenes are quickly silenced in murine embryonic carcinoma P19 cells. The silencing was correlated with CpG hypermethylation in the transgene promoter. Using high-resolution sodium bisulf...

journal_title：Journal of virology

authors： He J,Yang Q,Chang LJ

更新日期：2005-11-01 00:00:00

abstract：:To investigate the relation between the polyoma tumor-specific transplantation antigen and the virus-coded proteins, mice were immunized by inoculation of a variety of viable polyoma virus mutants and then challenged with polyoma virus-induced tumors. Two classes of early region mutants were used. One class produces a...

journal_title：Journal of virology

authors： Dalianis T,Magnusson G,Ito Y,Klein G

更新日期：1982-09-01 00:00:00

abstract：:Hepatitis C virus (HCV) replication in infected patients produces large and diverse viral populations, which give rise to drug-resistant and immune escape variants. Here, we analyzed HCV populations during transmission and diversification in longitudinal and cross-sectional samples using 454/Roche pyrosequencing, in t...

journal_title：Journal of virology

authors： Wang GP,Sherrill-Mix SA,Chang KM,Quince C,Bushman FD

更新日期：2010-06-01 00:00:00

abstract：:Cottontail rabbit papillomavirus induces strictly epithelial tumors in both cottontail and domestic rabbits. A high proportion of the initial benign papillomas progress within 8 to 14 months to invasive carcinomas. With the help of mRNA-specific riboprobes for E6, E7, E1, E2, L1 and L2, we investigated by in situ hybr...

journal_title：Journal of virology

authors： Zeltner R,Borenstein LA,Wettstein FO,Iftner T

更新日期：1994-06-01 00:00:00

abstract：:Both exponentially growing and serum-arrested subcloned CV-1 cell cultures were infected with simian virus 40 (SV40). By 24 h after infection 96% of the nuclei of these permissive cells contained SV40 T-antigen. Analysis of the average DNA content per cell at various times after infection indicated that by 24 h most o...

journal_title：Journal of virology

authors： Gershey EL

更新日期：1979-04-01 00:00:00

abstract：:Varicella-zoster virus (VZV) DNA was prepared from nucleocapsids and from enveloped virions of a laboratory strain (Ellen) and directly from the vesicle fluids of patients with zoster infections. VZV Ellen nucleocapsid DNA was cleaved with 11 different restriction endonucleases and electrophoresed in agarose gels. The...

journal_title：Journal of virology

authors： Straus SE,Aulakh HS,Ruyechan WT,Hay J,Casey TA,Vande Woude GF,Owens J,Smith HA

更新日期：1981-11-01 00:00:00

abstract：:This paper reports the use of zonal ultracentrifuge techniques to conduct biophysical studies of rhinoviruses grown with WI-38 cells. Good clean-out of infectivity from rhinovirus harvests was obtained with the continuous-flow B-V and B-IX rotors. Use of the B-V rotor resulted in the successful concentration of rhinov...

journal_title：Journal of virology

authors： Gerin JL,Richter WR,Fenters JD,Holper JC

更新日期：1968-09-01 00:00:00

abstract：:An infectious cDNA clone of a genotype 3 strain of hepatitis E virus adapted to growth in HepG2/C3A human hepatoma cells was constructed. This virus was unusual in that the hypervariable region of the adapted virus contained a 171-nucleotide insertion that encoded 58 amino acids of human S17 ribosomal protein. Analyse...

journal_title：Journal of virology

authors： Shukla P,Nguyen HT,Faulk K,Mather K,Torian U,Engle RE,Emerson SU

更新日期：2012-05-01 00:00:00

abstract：:We have used linker scanning and site-directed mutagenesis in an attempt to distinguish among the known functions of the duck hepatitis B virus large envelope protein, p36. We found that linker-encoded amino acid substitutions in at least one region of the pre-S envelope protein p36 produced defects in both the produc...

journal_title：Journal of virology

authors： Lenhoff RJ,Summers J

更新日期：1994-07-01 00:00:00

abstract：:Influenza B virus (IBV) is considered a major human pathogen, responsible for seasonal epidemics of acute respiratory illness. Two antigenically distinct IBV hemagglutinin (HA) lineages cocirculate worldwide with little cross-reactivity. Live attenuated influenza virus (LAIV) vaccines have been shown to provide better...

journal_title：Journal of virology

authors： Santos JJS,Finch C,Sutton T,Obadan A,Aguirre I,Wan Z,Lopez D,Geiger G,Gonzalez-Reiche AS,Ferreri L,Perez DR

更新日期：2017-05-26 00:00:00

abstract：:PEPSCAN analysis has been used to characterize the immunogenic regions of the capsid protein (CP) in virions of plum pox potyvirus (PPV). In addition to the well-known highly immunogenic N- and C-terminal domains of CP, regions within the core domain of the protein have also shown high immunogenicity. Moreover, the N ...

journal_title：Journal of virology

authors： Fernández-Fernández MR,Martínez-Torrecuadrada JL,Roncal F,Domínguez E,García JA

更新日期：2002-12-01 00:00:00

abstract：:Muscle is an attractive target for gene delivery because of its mass and because vectors can be delivered in a noninvasive fashion. Adeno-associated virus (AAV) has been shown to be effective for muscle-targeted gene transfer. Recent progress in characterization of AAV serotype 1 (AAV1) and AAV6 demonstrated that thes...

journal_title：Journal of virology

authors： Hauck B,Xiao W

更新日期：2003-02-01 00:00:00

abstract：:AIDS vaccination has a pressing need for more potent vaccination vectors capable of eliciting strong, diversified, and long-lasting cellular immune responses against human immunodeficiency virus (HIV). Lentiviral vectors have demonstrated efficiency not only as gene delivery vehicles for gene therapy applications but ...

journal_title：Journal of virology

authors： Beignon AS,Mollier K,Liard C,Coutant F,Munier S,Rivière J,Souque P,Charneau P

更新日期：2009-11-01 00:00:00

abstract：:The retroviral restriction factor TRIMCyp, derived from the TRIM5 gene, blocks replication at a postentry step. TRIMCyp has so far been found in four species of Asian macaques, Macaca fascicularis, M. mulatta, M. nemestrina, and M. leonina. M. fascicularis is commonly used as a model for AIDS research, but TRIMCyp has...

journal_title：Journal of virology

authors： Dietrich EA,Brennan G,Ferguson B,Wiseman RW,O'Connor D,Hu SL

更新日期：2011-10-01 00:00:00

abstract：:We established previously that the temperature-dependent host range mutant, td CE 3, of vesicular stomatitis virus (VSV) New Jersey possesses temperature-sensitive RNA transcriptase activity. In this paper, we describe dissociation and reconstitution experiments designed to determine which VSV polypeptide is affected ...

journal_title：Journal of virology

authors： Szilágyi JF,Pringle CR,Macpherson TM

更新日期：1977-05-01 00:00:00

abstract：:Xenotropic murine leukemia virus-related virus (XMRV) is a novel human gammaretrovirus discovered in association with human prostate tumors. XMRV was first identified in prostate stromal cells surrounding the tumors of patients carrying a mutation in the HPC1 gene locus. To determine the tropism of XMRV in cell cultur...

journal_title：Journal of virology

authors： Rodriguez JJ,Goff SP

更新日期：2010-03-01 00:00:00

abstract：:Hepatitis delta virus (HDV) contains a circular RNA genome of 1.7 kb. HDV RNA replication is thought to proceed via a rolling-circle mechanism that is dependent on autocatalytic cleavage and ligation reactions. However, it has never been established that these ribozyme activities are indeed involved in HDV RNA replica...

journal_title：Journal of virology

authors： Macnaughton TB,Wang YJ,Lai MM

更新日期：1993-04-01 00:00:00

abstract：:Herpes simplex virus (HSV) strains HSV type 1 (HSV-1) KOS and HSV-2 186 are representative of delayed and early shutoff strains, respectively, with regard to their ability to inhibit protein synthesis in Friend erythroleukemia cells. When these cells were simultaneously infected with HSV-1 KOS and HSV-2 186, HSV-1 KOS...

journal_title：Journal of virology

authors： Hill TM,Sadler JR,Betz JL

更新日期：1985-10-01 00:00:00

abstract：:A window of opportunity for immune responses to extinguish human immunodeficiency virus type 1 (HIV-1) exists from the moment of transmission through establishment of the latent pool of HIV-1-infected cells. A critical time to study the initial immune responses to the transmitted/founder virus is the eclipse phase of ...

journal_title：Journal of virology

authors： Tomaras GD,Yates NL,Liu P,Qin L,Fouda GG,Chavez LL,Decamp AC,Parks RJ,Ashley VC,Lucas JT,Cohen M,Eron J,Hicks CB,Liao HX,Self SG,Landucci G,Forthal DN,Weinhold KJ,Keele BF,Hahn BH,Greenberg ML,Morris L,Karim S

更新日期：2008-12-01 00:00:00

abstract：:Upon inoculation into AKR mice, mink cell focus-forming murine leukemia virus (MCF MLV) accelerates thymic lymphoma formation. During the preleukemic phase of disease, we observed the induction of apoptosis in thymic lymphocytes. A similar induction of apoptosis was observed for cultured mink epithelial cells after MC...

journal_title：Journal of virology

authors： Nanua S,Yoshimura FK

更新日期：2004-05-01 00:00:00

abstract：:Virion protein 16 (VP16) of herpes simplex virus type 1 (HSV-1) is a potent transcriptional activator of viral immediate-early (IE) genes. The VP16 activation domain can recruit various transcriptional coactivators to target gene promoters. However, the role of transcriptional coactivators in HSV-1 IE gene expression ...

journal_title：Journal of virology

authors： Kutluay SB,DeVos SL,Klomp JE,Triezenberg SJ

更新日期：2009-04-01 00:00:00