Abstract:
:Brain imaging studies suggest localization of verbal working memory in the left dorsolateral prefrontal cortex (DLPFC) while face processing and memory is localized in the inferior temporal cortex and other brain areas. The goal of this study was to assess the effect of left DLPFC low-frequency repetitive transcranial magnetic stimulation (rTMS) on verbal recall and face recognition. The study revealed a significant decrease of free recall in word encoding under rTMS (110% of motor threshold, 0.9 Hz) in comparison with sham stimulation (p=0.03), while no significant difference was found with facial memory tests. Our findings support the essential role of the left DLPFC in word but not facial memory and confirm the content specific arrangement of cortical areas involved in semantic memory. As a non-invasive tool, rTMS is useful for cognitive brain mapping and the functional localization of the category specific memory system.
journal_name
Physiol Resjournal_title
Physiological researchauthors
Skrdlantová L,Horácek J,Dockery C,Lukavský J,Kopecek M,Preiss M,Novák T,Höschl Csubject
Has Abstractpub_date
2005-01-01 00:00:00pages
123-8issue
1eissn
0862-8408issn
1802-9973journal_volume
54pub_type
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