Optimization of the accuracy of retention and washout measurements of 99mTc-Sestamibi from breast tumours using an anthropomorphic phantom.

abstract：:Transcranial direct current stimulation (tDCS) is a neuromodulation scheme where a small current is delivered to the brain via two electrodes attached to the scalp. The electrode design is an important topic, not only as regards efficacy, but also from a safety perspective, as tDCS may be related to skin lesions that ...

journal_title：Physics in medicine and biology

authors： Gomez-Tames J,Sugiyama Y,Laakso I,Tanaka S,Koyama S,Sadato N,Hirata A

更新日期：2016-12-21 00:00:00

abstract：:A pencil beam model for the calculation of the lateral scattering in water of protons for any therapeutic energy and depth is presented. It is based on the full Molière theory, taking into account the energy loss and the effects of mixtures and compounds. Concerning the electromagnetic part, the model has no free para...

journal_title：Physics in medicine and biology

authors： Bellinzona EV,Ciocca M,Embriaco A,Ferrari A,Fontana A,Mairani A,Parodi K,Rotondi A,Sala P,Tessonnier T

更新日期：2016-02-21 00:00:00

abstract：:Contemporary imaging modalities can now provide the surgeon with high quality three- and four-dimensional images depicting not only normal anatomy and pathology, but also vascularity and function. A key component of image-guided surgery (IGS) is the ability to register multi-modal pre-operative images to each other an...

journal_title：Physics in medicine and biology

authors： Peters TM

更新日期：2006-07-21 00:00:00

abstract：:Effects of different scatter compensation methods incorporated in fully 3D iterative reconstruction are investigated. The methods are: (i) the inclusion of an 'ideal scatter estimate' (ISE); (ii) like (i) but with a noiseless scatter estimate (ISE-NF); (iii) incorporation of scatter in the point spread function during...

journal_title：Physics in medicine and biology

authors： Beekman FJ,Kamphuis C,Frey EC

更新日期：1997-08-01 00:00:00

abstract：:We consider several inverse problems motivated by elastography. Given the (possibly transient) displacement field measured everywhere in an isotropic, compressible, linear elastic solid, and given density rho, determine the Lamé parameters lambda and mu. We consider several special cases of this problem: (a) for mu kn...

journal_title：Physics in medicine and biology

authors： Barbone PE,Oberai AA

更新日期：2007-03-21 00:00:00

abstract：:Fluorescence molecular imaging/tomography may play an important future role in preclinical research and clinical diagnostics. Time- and frequency-domain fluorescence imaging can acquire more measurement information than the continuous wave (CW) counterpart, improving the image quality of fluorescence molecular tomogra...

journal_title：Physics in medicine and biology

authors： Lu Y,Zhu B,Shen H,Rasmussen JC,Wang G,Sevick-Muraca EM

更新日期：2010-08-21 00:00:00

abstract：:This paper presents two 4D mathematical observer models for the detection of motion defects in 4D gated medical images. Their performance was compared with results from human observers in detecting a regional motion abnormality in simulated 4D gated myocardial perfusion (MP) SPECT images. The first 4D mathematical obs...

journal_title：Physics in medicine and biology

authors： Lee TS,Frey EC,Tsui BM

更新日期：2015-04-07 00:00:00

abstract：:The use of liquid ionization chambers in radiotherapy has grown during the past few years. While for air ionization chambers the k(TP) correction for air mass density due to pressure and temperature variations is well known, less work has been done on the case of liquid ionization chambers, where there is still the ne...

journal_title：Physics in medicine and biology

authors： Gómez F,González-Castaño D,Díaz-Botana P,Pardo-Montero J

更新日期：2014-06-07 00:00:00

abstract：:A novel radiation targeted therapy is investigated for HER-2 positive breast cancers. The proposed concept combines two known approaches, but never used together for the treatment of advanced, relapsed or metastasized HER-2 positive breast cancers. The proposed radiation binary targeted concept is based on the anti HE...

journal_title：Physics in medicine and biology

authors： Mundy DW,Harb W,Jevremovic T

更新日期：2006-03-21 00:00:00

abstract：:Monte Carlo (MC) algorithms are recognized as the most accurate methodology for patient dose assessment. For intensity-modulated radiation therapy (IMRT) delivered with dynamic multileaf collimators (DMLCs), accurate dose calculation, even with MC, is challenging. Accurate IMRT MC dose calculations require inclusion o...

journal_title：Physics in medicine and biology

authors： Siebers JV,Keall PJ,Kim JO,Mohan R

更新日期：2002-09-07 00:00:00

abstract：:In this work, we investigate longitudinal sampling and aliasing effects in multi-slice helical CT. We demonstrate that longitudinal aliasing can be a significant, complicated, and potentially detrimental effect in multi-slice helical CT reconstructions. Multi-slice helical CT scans are generally undersampled longitudi...

journal_title：Physics in medicine and biology

authors： La Rivière PJ,Pan X

更新日期：2002-08-07 00:00:00

abstract：:Accurate real-time prediction of respiratory motion is desirable for effective motion management in radiotherapy for lung tumor targets. Recently, nonparametric methods have been developed and their efficacy in predicting one-dimensional respiratory-type motion has been demonstrated. To exploit the correlation among v...

journal_title：Physics in medicine and biology

authors： Ruan D,Keall P

更新日期：2010-06-07 00:00:00

abstract：:The dynamic collimation system (DCS) can be combined with pencil beam scanning proton therapy to deliver highly conformal treatment plans with unique collimation at each energy layer. This energy layer-specific collimation is accomplished through the synchronized motion of four trimmer blades that intercept the proton...

journal_title：Physics in medicine and biology

authors： Smith BR,Hyer DE,Flynn RT,Hill PM,Culberson WS

更新日期：2019-10-21 00:00:00

abstract：:Three-dimensional reconstruction of coronary arteries can be performed during x-ray-guided interventions by gated reconstruction from a rotational coronary angiography sequence. Due to imperfect gating and cardiac or breathing motion, the heart's motion state might not be the same in all projections used for the recon...

journal_title：Physics in medicine and biology

authors： Hansis E,Schäfer D,Dössel O,Grass M

更新日期：2008-07-21 00:00:00

abstract：:In modern radiotherapy the verification of complex treatments plans is often performed in inhomogeneous or even anthropomorphic phantoms. For dose verification small detectors are necessary and therefore alanine detectors are most suitable. Though the response of alanine for a wide range of clinical photon energies in...

journal_title：Physics in medicine and biology

authors： von Voigts-Rhetz P,Anton M,Vorwerk H,Zink K

更新日期：2016-02-07 00:00:00

abstract：:The design and performance of a dosimetric system for the irradiation of thin biological samples with therapeutic proton beams is reported. Protons with initial energies between 40 MeV and 250 MeV are degraded with polystyrene blocks of variable thickness in order to place the sample, an aqueous layer of 10 microm thi...

journal_title：Physics in medicine and biology

authors： Bashkirov V,Schulte RW

更新日期：2002-02-07 00:00:00

abstract：:A transformation method was investigated for applying the MIRD absorbed fraction to internal dose calculations for an individual. The transformation method consists of two parts, transformation of the target organ mass, and of the distance between source and target organs. The variation of the specific absorbed fracti...

journal_title：Physics in medicine and biology

authors： Yamaguchi H,Kato Y,Shiragai A

更新日期：1975-07-01 00:00:00

abstract：:Maximum likelihood estimation (MLE) is presented as a statistical tool to evaluate the contribution of measurement error to any measurement series where the same quantity is measured using different independent methods. The technique was tested against artificial data sets; generated for values of underlying variation...

journal_title：Physics in medicine and biology

authors： Sage JP,Mayles WP,Mayles HM,Syndikus I

更新日期：2014-10-21 00:00:00

abstract：:Monte Carlo simulation with PENELOPE (version 2003) is applied to calculate Leksell Gamma Knife dose distributions for heterogeneous phantoms. The usual spherical water phantom is modified with a spherical bone shell simulating the skull and an air-filled cube simulating the frontal or maxillary sinuses. Different sim...

journal_title：Physics in medicine and biology

authors： Al-Dweri FM,Rojas EL,Lallena AM

更新日期：2005-12-07 00:00:00

abstract：:The prompt-gamma neutron activation facility at Brookhaven National Laboratory was upgraded to improve both the precision and accuracy of its in vivo determinations of total body nitrogen. The upgrade, guided by Monte Carlo simulations, involved elongating and modifying the source collimator and its shielding, reposit...

journal_title：Physics in medicine and biology

authors： Dilmanian FA,Lidofsky LJ,Stamatelatos I,Kamen Y,Yasumura S,Vartsky D,Pierson RN Jr,Weber DA,Moore RI,Ma R

更新日期：1998-02-01 00:00:00

abstract：:Four dimensional cone beam computed tomography (4DCBCT) uses a constant gantry speed and imaging frequency that are independent of the patient's breathing rate. Using a technique called respiratory motion guided 4DCBCT (RMG-4DCBCT), we have previously demonstrated that by varying the gantry speed and imaging frequency...

journal_title：Physics in medicine and biology

authors： O'Brien RT,Stankovic U,Sonke JJ,Keall PJ

更新日期：2017-06-07 00:00:00

abstract：:In recent years, optical techniques based on diffusion approximation have demonstrated their ability to gain rich spectral information about bone. However, these methods normally assume homogeneity, while cancellous bone and marrow form a highly heterogeneous two-phase medium. This paper studies the limitations of thi...

journal_title：Physics in medicine and biology

authors： Margallo-Balbás E,Taroni P,Pifferi A,Koolstra JH,v Ruijven LJ,French PJ

更新日期：2010-09-07 00:00:00

abstract：:State of the art point-spread function (PSF) corrections implemented in positron emission tomography/computed tomography (PET/CT) reconstruction improved image quality and diagnostic performance but caused an increase in the standardized uptake value (SUV) compared to a conventional OSEM reconstruction system. The EAN...

journal_title：Physics in medicine and biology

authors： Ferretti A,Chondrogiannis S,Rampin L,Bellan E,Marzola MC,Grassetto G,Gusella S,Maffione AM,Gava M,Rubello D

更新日期：2018-11-26 00:00:00

abstract：:Microbeam radiation therapy (MRT) is a treatment approach in radiation therapy where the treatment field is spatially fractionated into arrays of a few tens of micrometre wide planar beams of unusually high peak doses separated by low dose regions of several hundred micrometre width. In preclinical studies, this treat...

journal_title：Physics in medicine and biology

authors： Debus C,Oelfke U,Bartzsch S

更新日期：2017-10-19 00:00:00

abstract：:Shear wave elastography (SWE) is a potential tool to non-invasively assess cardiac muscle stiffness. This study focused on the effect of the orthotropic material properties and mechanical loading on the performance of cardiac SWE, as it is known that these factors contribute to complex 3D anisotropic shear wave propag...

journal_title：Physics in medicine and biology

authors： Caenen A,Pernot M,Peirlinck M,Mertens L,Swillens A,Segers P

更新日期：2018-03-23 00:00:00

abstract：:Dynamic 18F-FDG PET with tracer kinetic modeling has the potential to noninvasively evaluate human liver inflammation using the FDG blood-to-tissue transport rate K 1. Accurate kinetic modeling of dynamic liver PET data and K 1 quantification requires the knowledge of dual-blood input function from the hepatic artery ...

journal_title：Physics in medicine and biology

authors： Zuo Y,Sarkar S,Corwin MT,Olson K,Badawi RD,Wang G

更新日期：2019-09-05 00:00:00

abstract：:In proton scanning systems that employ active energy variation for depth modulation, a switch of the particle energy might typically require 1-2 s. For plans comprising many energy slices, these seconds could sum up to a non-negligible fraction of the total treatment duration. We have applied the Nyquist-Shannon sampl...

journal_title：Physics in medicine and biology

authors： Kang JH,Wilkens JJ,Oelfke U

更新日期：2008-05-07 00:00:00

abstract：:Low-strength anastomoses and thermal damage of tissue are major concerns in laser tissue welding techniques where laser energy is used to induce thermal changes in the molecular structure of the tissues being joined, hence allowing them to bond together. Laser tissue soldering, on the other hand, is a bonding techniqu...

journal_title：Physics in medicine and biology

authors： McNally KM,Sorg BS,Welch AJ,Dawes JM,Owen ER

更新日期：1999-04-01 00:00:00

abstract：:Wafer-scale CMOS active pixel sensors (APSs) have been developed recently for x-ray imaging applications. The small pixel pitch and low noise are very promising properties for medical imaging applications such as digital breast tomosynthesis (DBT). In this work, we evaluated experimentally and through modeling the ima...

journal_title：Physics in medicine and biology

authors： Zhao C,Konstantinidis AC,Zheng Y,Anaxagoras T,Speller RD,Kanicki J

更新日期：2015-12-07 00:00:00

abstract：:A solid dynamic phantom with tissue-like optical properties is presented, which contains seven discrete targets impregnated with thermochromic pigment located at different depths from the surface. Changes in absorption are obtained in response to localized heating of the targets, simulating haemodynamic changes occurr...

journal_title：Physics in medicine and biology

authors： Correia T,Banga A,Everdell NL,Gibson AP,Hebden JC

更新日期：2009-10-21 00:00:00