Effects of bone- and air-tissue inhomogeneities on the dose distributions of the Leksell Gamma Knife calculated with PENELOPE.

abstract：:Approximately 70% of acute coronary artery disease is caused by unstable (vulnerable) plaques with an inflammation of the overlying cap and high lipid content. A rupturing of the inflamed cap of the plaque results in propagation of the thrombus into the lumen, blockage of the artery and acute ischaemic syndrome or sud...

journal_title：Physics in medicine and biology

authors： Shikhaliev PM,Xu T,Ducote JL,Easwaramoorthy B,Mukherjee J,Molloi S

更新日期：2006-02-21 00:00:00

abstract：:Magnetoencephalography (MEG) is a non-invasive functional imaging modality based on the measurement of the external magnetic field produced by neural current sources within the brain. The reconstruction of the underlying sources is a severely ill-posed inverse problem typically tackled using either low-dimensional par...

journal_title：Physics in medicine and biology

authors： Jerbi K,Mosher JC,Baillet S,Leahy RM

更新日期：2002-02-21 00:00:00

abstract：:Volumetric scintillation dosimetry has the potential to provide fast, high-resolution, three-dimensional radiation dosimetry. However, scintillators exhibit a nonlinear response at the high linear energy transfer (LET) values characteristic of proton Bragg peaks. The purpose of this study was to develop a quenching co...

journal_title：Physics in medicine and biology

authors： Robertson D,Mirkovic D,Sahoo N,Beddar S

更新日期：2013-01-21 00:00:00

abstract：:The signal properties of polycrystalline mercuric iodide (HgI2) film detectors, under irradiation conditions relevant to mammographic, radiographic, fluoroscopic and radiotherapy x-ray imaging, are reported. Each film detector consists of an approximately 230 to approximately 460 microm thick layer of HgI2 (fabricated...

journal_title：Physics in medicine and biology

authors： Su Z,Antonuk LE,El-Mohri Y,Hu L,Du H,Sawant A,Li Y,Wang Y,Yamamoto J,Zhao Q

更新日期：2005-06-21 00:00:00

abstract：:Three-dimensional reconstruction of cardiac vasculature from angiographic C-arm CT (rotational angiography) data is a major challenge. Motion artefacts corrupt image quality, reducing usability for diagnosis and guidance. Many state-of-the-art approaches depend on retrospective ECG-gating of projection data for image ...

journal_title：Physics in medicine and biology

authors： Schwemmer C,Rohkohl C,Lauritsch G,Müller K,Hornegger J

更新日期：2013-06-07 00:00:00

abstract：:The transverse magnetic field of an MRI-linac sweeps contaminant electrons away from the radiation beam. Films oriented perpendicular to the magnetic field and 5 cm from the radiation beam edge show a projection of the divergent beam, indicating that contaminant electrons spiral along magnetic field lines and deposit ...

journal_title：Physics in medicine and biology

authors： Hackett SL,van Asselen B,Wolthaus JWH,Bluemink JJ,Ishakoglu K,Kok J,Lagendijk JJW,Raaymakers BW

更新日期：2018-05-01 00:00:00

abstract：:The accuracy of delivered radiation dose and the reproducibility of employed radiotherapy methods are key factors for preclinical radiobiology applications and research studies. In this work, ionization chamber (IC) measurements and Monte Carlo (MC) simulations were used to accurately determine the dose rate for total...

journal_title：Physics in medicine and biology

authors： Zhong Y,Lai Y,Saha D,Story MD,Jia X,Stojadinovic S

更新日期：2020-09-08 00:00:00

abstract：:We tested the ability of a single Compton camera (CC) to produce 3-dimensional (3D) images of prompt gammas (PGs) emitted during the irradiation of a tissue-equivalent plastic phantom with proton pencil beams for clinical doses delivered at clinical dose rates. PG measurements were made with a small prototype CC place...

journal_title：Physics in medicine and biology

authors： Draeger E,Mackin D,Peterson S,Chen H,Avery S,Beddar S,Polf JC

更新日期：2018-01-30 00:00:00

abstract：:Magnetic resonance-guided radiation therapy (MR-GRT) offers great potential to improve radiation treatment outcomes by providing more accurate and patient-tailored therapy. Despite superior soft tissue contrast in MRI, one of the challenges towards MRI-only workflows is that the process often requires some sort of 'MR...

journal_title：Physics in medicine and biology

authors： Nosrati R,Paudel M,Ravi A,Pejovic-Milic A,Morton G,Stanisz GJ

更新日期：2019-07-16 00:00:00

abstract：:A method using both patient geometric and dosimetric information was proposed to predict dose-volume histograms (DVHs) of organs at risk (OARs) for a nasopharyngeal cancer (NPC) intensity-modulated radiation therapy (IMRT) plan. A total of 106 nine-field IMRT NPC plans were used in this study. Twenty-six plans were ra...

journal_title：Physics in medicine and biology

authors： Jiao SX,Chen LX,Zhu JH,Wang ML,Liu XW

更新日期：2019-12-05 00:00:00

abstract：:As a new method, x-ray diffraction enhanced imaging (DEI) has extremely high sensitivity for weakly absorbing low-Z samples in medical and biological fields. Conventional performance parameters, such as spatial resolution and low-contrast resolution, are not enough to describe the characteristics of a DEI system. This...

journal_title：Physics in medicine and biology

authors： Huang ZF,Kang KJ,Li Z

更新日期：2006-06-21 00:00:00

abstract：:A new function to treat tetrahedral-mesh geometry was implemented in the particle and heavy ion transport code systems. To accelerate the computational speed in the transport process, an original algorithm was introduced to initially prepare decomposition maps for the container box of the tetrahedral-mesh geometry. Th...

journal_title：Physics in medicine and biology

authors： Furuta T,Sato T,Han MC,Yeom YS,Kim CH,Brown JL,Bolch WE

更新日期：2017-06-21 00:00:00

abstract：:Scatter correction is a prerequisite for quantitative SPECT, but potentially increases noise. Monte Carlo simulations (EGS4) and physical phantom measurements were used to compare accuracy and noise properties of two scatter correction techniques: the triple-energy window (TEW), and the transmission dependent convolut...

journal_title：Physics in medicine and biology

authors： Narita Y,Eberl S,Iida H,Hutton BF,Braun M,Nakamura T,Bautovich G

更新日期：1996-11-01 00:00:00

abstract：:An important aspect of robotic radiation therapy is active compensation of target motion. Recently, ultrasound has been proposed to obtain real-time volumetric images of abdominal organ motion. One approach to realize flexible probe placement throughout the treatment fraction is based on a robotic arm holding the ultr...

journal_title：Physics in medicine and biology

authors： Schlüter M,Fürweger C,Schlaefer A

更新日期：2019-10-04 00:00:00

abstract：:Several studies have been appeared, up to now, that indicate the effect of accurate simulation on dose received by different substructures of the eye, irradiated by external beams of short-range radiation such as electron. Different representations of the eye have consequently been introduced. Their accuracies depend ...

journal_title：Physics in medicine and biology

authors： Vejdani-Noghreiyan A,Ebrahimi-Khankook A

更新日期：2019-07-02 00:00:00

abstract：:The goals of this study were (1) to characterize the optical artefacts affecting measurement accuracy in a volumetric liquid scintillator detector, and (2) to develop methods to correct for these artefacts. The optical artefacts addressed were photon scattering, refraction, camera perspective, vignetting, lens distort...

journal_title：Physics in medicine and biology

authors： Robertson D,Hui C,Archambault L,Mohan R,Beddar S

更新日期：2014-01-06 00:00:00

abstract：:The electron pencil-beam redefinition algorithm (PBRA), which is used to calculate electron beam dose distributions, assumes that the virtual source of each pencil beam is identical to that of the broad beam incident on the patient. In the present work, a virtual source specific for each pencil beam is modelled by inc...

journal_title：Physics in medicine and biology

authors： Boyd RA,Hogstrom KR,White RA,Starkschall G

更新日期：2001-11-01 00:00:00

abstract：:Coronary computed tomography angiography (cCTA) is a commonly used imaging modality for the evaluation of coronary artery disease. cCTA is generally reconstructed in multiple cardiac phases because different coronary arteries may be better visualized in some phases than in others due to the periodic cardiac motion. We...

journal_title：Physics in medicine and biology

authors： Hadjiiski L,Zhou C,Chan HP,Chughtai A,Agarwal P,Kuriakose J,Kazerooni E,Wei J,Patel S

更新日期：2014-08-21 00:00:00

abstract：:Motion mitigation strategies are crucial for scanned particle therapy of mobile tumours in order to prevent geometrical target miss and interplay effects. We developed a patient-specific respiratory motion model based on simultaneously acquired time-resolved volumetric MRI and 2D abdominal ultrasound images. We presen...

journal_title：Physics in medicine and biology

authors： Giger AT,Krieger M,Jud C,Duetschler A,Salomir R,Bieri O,Bauman G,Nguyen D,Weber DC,Lomax AJ,Zhang Y,Cattin PC

更新日期：2020-07-28 00:00:00

abstract：:The purpose of this paper is to evaluate the ability of a prototype Compton camera (CC) to measure prompt gamma rays (PG) emitted during delivery of clinical proton pencil beams for prompt gamma imaging (PGI) as a means of providing in vivo verification of the delivered proton radiotherapy beams. A water phantom was i...

journal_title：Physics in medicine and biology

authors： Polf JC,Avery S,Mackin DS,Beddar S

更新日期：2015-09-21 00:00:00

abstract：:In this study, the safety compliance for nonuniform field exposures is discussed using coupling factor concepts. The coupling factor, which is defined in the International Electrotechnical Commission 62311 standard, is extended to consider the effects of harmonics and also to apply to the specific absorption rate (for...

journal_title：Physics in medicine and biology

authors： Sunohara T,Hirata A,Laakso I,De Santis V,Onishi T

更新日期：2015-10-21 00:00:00

abstract：:A novel approach to read out radiochromic film was introduced recently by the manufacturer of GafChromic film. In this study, the performance of this triple-channel film dosimetry method was compared against the conventional single-red-channel film dosimetry procedure, with and without inclusion of a pre-irradiation (...

journal_title：Physics in medicine and biology

authors： van Hoof SJ,Granton PV,Landry G,Podesta M,Verhaegen F

更新日期：2012-07-07 00:00:00

abstract：:Many applications in medical imaging include image registration for matching of images from the same or different modalities. In the case of full data sampling, the respective reconstructed images are usually of such a good image quality that standard deformable volume-to-volume (3D-3D) registration approaches can be ...

journal_title：Physics in medicine and biology

authors： Flach B,Brehm M,Sawall S,Kachelrieß M

更新日期：2014-12-21 00:00:00

abstract：:K line x-ray fluorescence (KXRF) measurements of bone lead have emerged as a promising new biological marker of internal lead dose in epidemiological studies. Some disagreements exist, however, over the analysis of data at low levels of bone lead concentration. In this study, we performed 30 serial measurements on eac...

journal_title：Physics in medicine and biology

authors： Kim R,Aro A,Rotnitzky A,Amarasiriwardena C,Hu H

更新日期：1995-09-01 00:00:00

abstract：:Computational phantoms are commonly used in internal radiation dosimetry to assess the amount and distribution pattern of energy deposited in various parts of the human body from different internal radiation sources. Radiation dose assessments are commonly performed on predetermined reference computational phantoms wh...

journal_title：Physics in medicine and biology

authors： Xie T,Kuster N,Zaidi H

更新日期：2017-07-13 00:00:00

abstract：:Compartmental models are widely used for the mathematical modelling of dynamic studies acquired with positron emission tomography (PET). The numerical problem involves the estimation of a sum of decaying real exponentials convolved with an input function. In exponential spectral analysis (SA), the nonlinear estimation...

journal_title：Physics in medicine and biology

authors： Turkheimer FE,Hinz R,Gunn RN,Aston JA,Gunn SR,Cunningham VJ

更新日期：2003-12-07 00:00:00

abstract：:Electromagnetic tracking technology is primarily used for continuous prostate localization during radiotherapy, but offers potential value for evaluation of dosimetric coverage and adequacy of treatment for dynamic targets. We developed a highly automated method for daily computation of cumulative dosimetric effects o...

journal_title：Physics in medicine and biology

authors： Noel CE,Santanam L,Olsen JR,Baker KW,Parikh PJ

更新日期：2010-01-07 00:00:00

abstract：:This paper reports a theoretical study on the distribution of blood flow in the human cardiovascular system when one or more blood vessels are affected by stenosis. The analysis employs a mathematical model of the entire system based on the finite element method. The arterial-venous network is represented by a large n...

journal_title：Physics in medicine and biology

authors： Sud VK,Srinivasan RS,Charles JB,Bungo MW

更新日期：1993-03-01 00:00:00

abstract：:This paper describes an accurate and time-efficient method for the determination of total body potassium via a combination of measurements in the Birmingham whole body counter and the use of the Monte Carlo n-particle (MCNP) simulation code. In developing this method, MCNP has also been used to derive values for some ...

journal_title：Physics in medicine and biology

authors： O'Hehir S,Green S,Beddoe AH

更新日期：2006-09-07 00:00:00

abstract：:Magnetic Particle Imaging (MPI) is a promising medical imaging technique for visualizing the three-dimensional distribution of tracer materials, specifically iron oxide nanoparticles (IONP). The optimization of magnetic nanoparticles (MNP) plays an essential role to improve the image resolution and sensitivity of imag...

journal_title：Physics in medicine and biology

authors： Arsalani S,Loewa N,Kosch O,Radon P,Baffa O,Wiekhorst F

更新日期：2020-11-23 00:00:00