Novel water-soluble photosensitizer based on starch and containing porphyrin.

abstract：:We compared mutagenesis and sister chromatid exchange (SCE) induction by 193 nm and 308 nm pulsed excimer laser radiation with 254 nm low intensity continuous wave UV light in Chinese hamster ovary (CHO) cells in culture. The 254 nm radiation was most mutagenic of the radiations, in accordance with expectation, and al...

journal_title：Photochemistry and photobiology

authors： Rasmussen RE,Hammer-Wilson M,Berns MW

更新日期：1989-04-01 00:00:00

abstract：:Cultured cells accumulate acridine orange (AO), which is a weak basic dye and a photosensitizer, in lysosomes and other acidic compartments. During exposure to blue light, AO-loaded macrophages show decreasing red granular fluorescence and increasing green diffuse fluorescence. This is hypothesized to represent peroxi...

journal_title：Photochemistry and photobiology

authors： Zdolsek JM,Olsson GM,Brunk UT

更新日期：1990-01-01 00:00:00

abstract：:Photochemo and photodynamic therapies are minimally invasive approaches for the treatment of cancers and powerful weapons for competing bacterial resistance to antibiotics. Synthetic and naturally occurring quinazolinones are considered privileged anticancer and antibacterial agents, with several of them to have emerg...

journal_title：Photochemistry and photobiology

authors： Panagopoulos A,Balalas T,Mitrakas A,Vrazas V,Katsani KR,Koumbis AE,Koukourakis MI,Litinas KE,Fylaktakidou KC

更新日期：2021-01-01 00:00:00

abstract：:Photoprotective formulations containing substances with antioxidant properties in combination have been used as a strategy for the improvement of photoaged skin conditions. However, there is a lack of studies evaluating the clinical efficacy of these substances in young women with signs of photoaging. Thus, the object...

journal_title：Photochemistry and photobiology

authors： Fossa Shirata MM,Maia Campos PMBG

更新日期：2021-02-02 00:00:00

abstract：:Photolysis of ester 1 in argon-saturated methanol and acetonitrile does not produce any product, whereas irradiation of 1 in oxygen-saturated methanol yields peroxide 2. Laser flash photolysis studies demonstrate that 1 undergoes intramolecular H atom abstraction to form biradical 3 (λmax ~340 nm), which intersystem c...

journal_title：Photochemistry and photobiology

authors： Das A,Lao EA,Gudmundsdottir AD

更新日期：2016-05-01 00:00:00

abstract：:Solar radiation is known to be a major contributor to the development of skin cancer. Most sunscreen formulations, including those with broad spectrum, offer minimal protection in long-wavelength ultraviolet A1 (UVA1; 370-400 nm) and visible light (VL; 400-700 nm) domain. There is limited information regarding the imp...

journal_title：Photochemistry and photobiology

authors： Kohli I,Zubair R,Lyons AB,Nahhas AF,Braunberger TL,Mokhtari M,Ruvolo E,Lim HW,Hamzavi IH

更新日期：2019-11-01 00:00:00

abstract：:The response of normal brain to photodynamic therapy (PDT) was investigated in 62 Fisher rats. The animals were injected i.p. with Photofrin II (12.5 mg/kg). Forty-eight hours following injection, an area of dura 5 mm in diameter over the frontal cortex was photoactivated with red light (632 +/- 2 nm) at 100 mW cm-2, ...

journal_title：Photochemistry and photobiology

authors： Dereski MO,Chopp M,Garcia JH,Hetzel FW

更新日期：1991-07-01 00:00:00

abstract：:The design, synthesis and application of a new fluorescent-labeling reagent for collagen has been developed as a prerequisite for the design of a photoactivated collagen-crosslinking compound for surgical wound closure. The amine groups in collagen are the targets of a rational design for a new fluorophore because nat...

journal_title：Photochemistry and photobiology

authors： Timberlake GT,Reddy GK,Stehno-Bittel L,Weber JF,Amslinger S,Givens RS

更新日期：2002-11-01 00:00:00

abstract：:Nucleotide excision repair and the ATR-mediated DNA damage checkpoint are two critical cellular responses to the genotoxic stress induced by ultraviolet (UV) light and are important for cancer prevention. In vivo genetic data indicate that these global responses are coupled. Aziz Sancar et al. developed an in vitro co...

journal_title：Photochemistry and photobiology

authors： Lindsey-Boltz LA

更新日期：2017-01-01 00:00:00

abstract：:Proton magnetic resonance imaging (MRI) and histological methods were used to evaluate photodynamic therapy (PDT)-induced hemorrhagic necrosis in the murine M1 tumor within 72 h of treatment of male DBA/2 mice. The effects of three photosensitizing drugs were investigated: Photofrin (n = 4), Zn (II) phthalocyanine (n ...

journal_title：Photochemistry and photobiology

authors： Winsborrow BG,Grondey H,Savoie H,Fyfe CA,Dolphin D

更新日期：1997-12-01 00:00:00

abstract：:The synthesis of a molecule containing hypericin and luciferin moieties joined by a tether is reported. The light-induced (in vitro) antiviral activity as well as the photophysical properties of this new compound are measured and compared with those of the parent compounds, hypericin and pseudohypericin. This tethered...

journal_title：Photochemistry and photobiology

authors： Wen J,Chowdhury P,Wills NJ,Wannemuehler Y,Park J,Kesavan S,Carpenter S,Kraus GA,Petrich JW

更新日期：2002-08-01 00:00:00

abstract：:Many viral infections reach clinical significance in winter, when it is cold, relative humidity is lowest and vitamin D production from solar ultraviolet-B irradiation is at its nadir. Several autoimmune diseases, such as multiple sclerosis, type 1 diabetes mellitus and asthma, are linked to viral infections. Vitamin ...

journal_title：Photochemistry and photobiology

authors： Grant WB

更新日期：2008-03-01 00:00:00

abstract：:The temperature dependence of the uptake phase of 5-aminolevulinic acid (ALA) and the following production phase of protoporphyrin IX (PpIX) in normal mouse skin was investigated. A cream containing 20% ALA was topically applied on the skin for 10 min. The amount of ALA-induced PpIX was evaluated by measuring the fluo...

journal_title：Photochemistry and photobiology

authors： Juzenas P,Sørensen R,Iani V,Moan J

更新日期：1999-04-01 00:00:00

abstract：:Photodynamic treatment of promyelocytic K562 cells in the presence of a monoglucosylporphyrin or hematoporphyrin leads to a sequence of events recognized as hallmarks of apoptosis: a drop in mitochondrial potential, concurrent with a drop in ATP level and a decrease in cell respiration, translocation of phosphatidylse...

journal_title：Photochemistry and photobiology

authors： Carré V,Jayat C,Granet R,Krausz P,Guilloton M

更新日期：1999-01-01 00:00:00

abstract：:The phototoxic anti-hyperlipoproteinemic drug fenofibrate was found to be photolabile under aerobic and anaerobic conditions. Irradiation under argon of a methanol solution of this drug produced the photoproducts isopropyl 4-(1-[4-chlorophenyl]-1,2-dihydroxy)ethylphenoxyisobutyrate, 1,2-bis(4-chlorophenyl)-1,2bis (4-[...

journal_title：Photochemistry and photobiology

authors： Vargas F,Canudas N,Miranda MA,Boscá F

更新日期：1993-10-01 00:00:00

abstract：:δ-Aminolevulinic acid (ALA)-induced porphyrin accumulation is widely used in the treatment of cancer, as photodynamic therapy. To clarify the mechanisms of the tumor-preferential accumulation of protoporphyrin, we examined the effect of the expression of heme-biosynthetic and -degradative enzymes on the ALA-induced ac...

journal_title：Photochemistry and photobiology

authors： Ohgari Y,Miyata Y,Miyagi T,Gotoh S,Ohta T,Kataoka T,Furuyama K,Taketani S

更新日期：2011-09-01 00:00:00

abstract：:A key challenge for microbiology is to understand how evolution has shaped the wiring of regulatory networks. This is amplified by the paucity of information of power-spectra of physicochemical stimuli to which microorganisms are exposed. Future studies of genome evolution, driven by altered stimulus regimes, will the...

journal_title：Photochemistry and photobiology

authors： van der Steen JB,Hellingwerf KJ

更新日期：2015-09-01 00:00:00

abstract：:This review focuses on damage photosensitized by the fluoroquinolone (FQ) antibacterial drugs. Different models are employed to study biosubstrate photodamage mediated by FQs (organisms, cells, isolated biomolecules and super molecules). Being that the effect of environment (polarity of the medium, ions, pH, binding w...

journal_title：Photochemistry and photobiology

authors： de Guidi G,Bracchitta G,Catalfo A

更新日期：2011-11-01 00:00:00

abstract：:Solar ultraviolet-B radiation (UVB) is essential for epidermal vitamin D production. We aimed to quantitate the relationship between personal solar UV exposure and serum 25hydroxy vitamin D (25[OH]D) concentration. Blood was collected for 25(OH)D analysis in 207 South Australian adults aged 27-61 years. At the time of...

journal_title：Photochemistry and photobiology

authors： Nair-Shalliker V,Clements M,Fenech M,Armstrong BK

更新日期：2013-01-01 00:00:00

abstract：:An important step in predicting the effects of future increases in UV radiation (UVR) is to evaluate the mechanisms that organisms use to prevent and repair DNA damage and determine how those mechanisms influence UVR sensitivity. Damage is prevented to varying degrees through photoprotection and repaired via two main ...

journal_title：Photochemistry and photobiology

authors： Olson MH,Mitchell DL

更新日期：2006-03-01 00:00:00

abstract：:A widely published expression for dipole strengths of optical transitions is found to require correction. The proposed adjustment, which involves the refractive index of the solvent in which the strengths are measured, may lead to significant changes in predictions that have been based on the equation. We discuss a cl...

journal_title：Photochemistry and photobiology

authors： Knox RS

更新日期：2003-05-01 00:00:00

abstract：:Photobiomodulation therapy (PBMT) has anti-inflammatory, analgesic and regenerative properties. This systematic review aimed to critically appraise the published data of in vivo human randomized clinical trials (RCTs), and present a comprehensive overview of the efficacy of PBMT, as an adjunct to the nonsurgical perio...

journal_title：Photochemistry and photobiology

authors： Dalvi S,Benedicenti S,Hanna R

更新日期：2020-10-24 00:00:00

abstract：:Near-UV (337 nm) photoactivation of the 5-hydroxytryptophan decarboxylation reaction producing serotonin has been observed. The photoactivation effect was investigated as a function of fluence rate and fluence, and pH. Photoactivation of decarboxylase activity was found to occur at nearly neutral pH values (low activi...

journal_title：Photochemistry and photobiology

authors： Fraikin GY,Strakhovskaya MG,Ivanova EV,Rubin AB

更新日期：1989-04-01 00:00:00

abstract：:The photosolvolysis of several biphenyl methanols (Ph-PhCH[Ph]OH) substituted with hydroxy or methoxy groups on the benzene ring not containing the -CH(Ph)OH moiety has been studied in aqueous solution. This work is a continuation of our studies of photosolvolysis of hydroxy-substituted arylmethanols that generate qui...

journal_title：Photochemistry and photobiology

authors： Xu M,Lukeman M,Wan P

更新日期：2006-01-01 00:00:00

abstract：:The tetraruthenated porphyrin, mu-[meso-5,10,15,20-tetra(pyridyl)porphyrin]tetrakis[bis-(bipyridine) chloride ruthenium(II)] (TRP) is a supramolecular cationic species. The aim of the present investigation was to evaluate the photodynamic properties of TRP and Zn-TRP to damage DNA with emphasis on the mechanistic aspe...

journal_title：Photochemistry and photobiology

authors： Ravanat JL,Cadet J,Araki K,Toma HE,Medeiros MH,Mascio PD

更新日期：1998-11-01 00:00:00

abstract：:Various photosensitizers were grafted by conventional peptide coupling methods to functionalized silica with several macroscopic shapes (powders, films) or embedded in highly transparent and microporous silica xerogel monoliths. Owing to the transparency and free-standing shape of the monoliths, the transient species ...

journal_title：Photochemistry and photobiology

authors： Ronzani F,Saint-Cricq P,Arzoumanian E,Pigot T,Blanc S,Oelgemöller M,Oliveros E,Richard C,Lacombe S

更新日期：2014-03-01 00:00:00

abstract：:Types of photoreceptor cells in the retinas of 36 species of vertebrates (5 classes, 14 orders) were investigated immunocytochemically with monoclonal antibodies against chicken iodopsin (Io-mAb) and antiserum against bovine rhodopsin (Rh-As). In mammals, Rh-As labeled the outer segments of some photoreceptor cells in...

journal_title：Photochemistry and photobiology

authors： Kawata A,Oishi T,Fukada Y,Shichida Y,Yoshizawa T

更新日期：1992-12-01 00:00:00

abstract：:The protein environments surrounding the retinal tune electronic absorption maximum from 350 to 630 nm. Hybrid quantum mechanical/molecular mechanical (QM/MM) methods can be used in calculating excitation energies of retinal in its native protein environments and in studying the molecular basis of spectral tuning. We ...

journal_title：Photochemistry and photobiology

authors： Altun A,Yokoyama S,Morokuma K

更新日期：2008-07-01 00:00:00

abstract：:A 24 h preculture of HT29-18 human colonic adenocarcinoma cells with the sterol synthesis inhibitor lovastatin at concentrations of 0.1-0.5 microM markedly increased the photocytotoxic effect of photofrin II delivered to cells by low density lipoproteins. Under the same conditions, LDL binding and photofrin II (PII) u...

journal_title：Photochemistry and photobiology

authors： Biade S,Mazière JC,Mora L,Santus R,Mazière C,Auclair M,Morlière P,Dubertret L

更新日期：1993-02-01 00:00:00

abstract：:High-altitude Andean lakes (HAAL) are a treasure chest for microbiological research in South America. Their indigenous microbial communities are exposed to extremely high UV irradiation and to multiple chemical extremes (Arsenic, high salt content, alkalinity). Microbes are found both, free-living or associated into m...

journal_title：Photochemistry and photobiology

authors： Albarracín VH,Gärtner W,Farias ME

更新日期：2016-01-01 00:00:00