Treatment of progressive outer retinal necrosis with sorivudine.

Abstract:

PURPOSE/METHODS:We examined a patient with progressive outer retinal necrosis, which is presumably caused by the varicella-zoster virus in patients with the acquired immunodeficiency syndrome. RESULTS/CONCLUSIONS:The patient was successfully treated with a combination of intravitreal ganciclovir and oral sorivudine. Treatment for progressive outer retinal necrosis has been disappointing; both acyclovir and ganciclovir have had only limited success. Sorivudine, a new antiviral medication with activity against varicella-zoster virus, may represent an effective alternative treatment for retinal necrosis.

journal_name

Am J Ophthalmol

authors

Pinnolis MK,Foxworthy D,Kemp B

doi

10.1016/s0002-9394(14)71242-5

subject

Has Abstract

pub_date

1995-04-01 00:00:00

pages

516-7

issue

4

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(14)71242-5

journal_volume

119

pub_type

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