Abstract：
PURPOSE:To characterize outcomes for patients who develop full-thickness macular holes after pars plana vitrectomy. METHODS:We retrospectively analyzed data for 47 consecutive patients (47 eyes) who developed full-thickness macular holes after initial pars plana vitrectomy for a variety of indications. All patients underwent a second vitrectomy and gas tamponade with or without internal limiting membrane peeling. RESULTS:Indications for initial vitrectomy included idiopathic epiretinal membranes (11 eyes), epiretinal membranes with a pseudohole (nine eyes), macular edema resulting from various conditions (nine eyes), proliferative diabetic retinopathy (nine eyes), rhegmatogenous retinal detachment (five eyes), and miscellaneous causes (four eyes). Mean interval from initial vitrectomy to macular hole formation was 20.4 months. Mean visual acuity (VA) in the affected eye was 0.13 (20/155, Snellen equivalent). The hole was closed in 32 eyes (68%) after a single procedure. With a mean follow-up of 53 months, mean final VA improved to 0.26 (20/77); 26 (55%) eyes improved, 18 (38%) were stable, and three (6%) worsened. No severe complications occurred except one macular hole that reopened after successful closure. CONCLUSIONS:Macular holes may develop after pars plana vitrectomy. Although additional vitrectomy can successfully close the hole and improve vision in most patients, postsurgical outcome seems to depend on the underlying condition.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Kumagai K,Ogino N,Furukawa M,Larson E,Uemura Adoi
10.1016/j.ajo.2008.01.030subject
Has Abstractpub_date
2008-06-01 00:00:00pages
1077-80issue
6eissn
0002-9394issn
1879-1891pii
S0002-9394(08)00092-5journal_volume
145pub_type
杂志文章abstract：:Nerve fiber counts of 16 normal human optic nerves from subjects aged 3.5 to 82 years showed a significant effect of age (P = .0207). The delay between death or enucleation and fixation also significantly affected the result (P = .0078). The mean (+/- S.E.M.) count for the 16 nerves was 1,244,005 +/- 20,033 fibers, gi...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
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更新日期：1995-10-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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pub_type： 临床试验,杂志文章
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：2005-03-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1985-02-15 00:00:00
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更新日期：1996-03-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1979-10-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1978-09-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.ajo.2006.01.016
更新日期：2006-06-01 00:00:00
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journal_title：American journal of ophthalmology
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更新日期：2003-08-01 00:00:00
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journal_title：American journal of ophthalmology
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journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1989-05-15 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1978-12-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1996-09-01 00:00:00
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更新日期：2002-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：2018-08-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1978-08-01 00:00:00
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journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：2016-10-01 00:00:00
abstract：:Pars plana vitrectomy and scleral buckling were performed on 22 eyes of 19 patients for treatment of perforating eye injuries from shotgun pellets. We reviewed the intraoperative findings at the time of vitrectomy to determine what factors might influence final visual acuity. The presence of a total retinal detachment...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
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更新日期：1992-07-15 00:00:00
abstract：PURPOSE:Low docosahexaenoic acid (DHA) in X-linked retinitis pigmentosa (XLRP) may influence retinal function. The goals of this study were to elevate blood DHA levels and determine the effect on the rate of disease progression. DESIGN:In a 4-year prospective randomized clinical trial, male patients with XLRP (mean ag...
journal_title：American journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2004-04-01 00:00:00
abstract：PURPOSE:Although congenital epiblepharon is a relatively common condition, particularly in Asians, acquired lower eyelid epiblepharon is rare. METHOD:We examined an 8-year-old boy who developed unilateral lower eyelid epiblepharon after a subciliary incisional approach for repair of a zygomatico-orbital fracture. RES...
journal_title：American journal of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0002-9394(14)72084-7
更新日期：1996-09-01 00:00:00
