Pre-chemotherapy hemoglobin levels and survival in patients with advanced epithelial ovarian cancer who received a first-line taxane/platinum-based regimen: results of a multicenter retrospective Italian study.

abstract：OBJECTIVE:To test whether platelets could increase invasion potential and initiate EMT in ovarian cancer cells via a TGF-β signaling pathway. METHODS:Blood samples were collected in 69 patients with ovarian cancer, 16 patients with benign ovarian tumor and 64 healthy donors. SK-OV-3 and OVCAR-3 ovarian cancer cells we...

journal_title：Gynecologic oncology

authors： Guo Y,Cui W,Pei Y,Xu D

更新日期：2019-06-01 00:00:00

abstract：:We have previously reported an overall response rate of 41% and a median survival duration of 14 months in a series of 49 patients with metastatic or recurrent endometrial carcinoma treated by a combination of etoposide, 5-fluorouracil, and cisplatin. In order to increase response rate and survival duration, doxorubic...

journal_title：Gynecologic oncology

authors： Pierga JY,Diéras V,Beuzeboc P,Dorval T,Palangié T,Jouve M,Scholl SM,Garcia-Giralt E,Pouillart P

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Practitioners and researchers require an outcome measure that accurately identifies the range of common treatment-induced changes in sexual function and well-being experienced by women after cervical or endometrial cancer. This systematic review critically appraised the measurement properties and clinical ut...

journal_title：Gynecologic oncology

authors： White ID,Sangha A,Lucas G,Wiseman T

更新日期：2016-12-01 00:00:00

abstract：:Of a group of 68 patients treated with standard polychemotherapy (CAP-5), 52 were evaluated by an early second-look laparotomy, preferably after three cycles of treatment. Of 21 patients with initial tumor residuals smaller than 2 cm, only 5 had residual tumor, and of 31 patients with tumor larger than 2 cm, 27 had re...

journal_title：Gynecologic oncology

authors： van Lith JM,Bouma J,Aalders JG,Boonstra H,Sleijfer DT,Willemse PH

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Although most patients at high risk of Gestational Trophoblastic Neoplasia (GTN) respond to standard treatments, there is a group of patients that will die because of it. The use of new single or combination drugs in this population has become a priority. CASE REPORT:We present the case of a relapsed high r...

journal_title：Gynecologic oncology

authors： Bianconi M,Jankilevich G,Otero S,Nassif J,Storino C

更新日期：2007-07-01 00:00:00

abstract：PURPOSE:The goal of this study was to determine whether South African HIV-seropositive women with invasive cervical cancer present with disease that is more advanced than that of HIV-seronegative women and whether degree of immunosuppression affects the extent of disease at initial presentation. METHODS:This study is ...

journal_title：Gynecologic oncology

authors： Lomalisa P,Smith T,Guidozzi F

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Malignant germ cell tumors of the ovary are often curative after conservative surgery and adjuvant chemotherapy. Persistent tumors despite normalization of serum tumor markers may represent retroconversion to benign masses, but this is rare in ovarian tumors without teratoma elements. The management in such ...

journal_title：Gynecologic oncology

authors： David YB,Weiss A,Shechtman L,Shalev E

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:The goals of this study were to evaluate the feasibility of pelvic intensity-modulated radiotherapy (IMRT) in the adjuvant treatment of gynecologic malignancies and to compare the dose-volume histograms (DVHs) and determine the potential impact on acute and long-term toxicity based on the dose to target and n...

journal_title：Gynecologic oncology

authors： Heron DE,Gerszten K,Selvaraj RN,King GC,Sonnik D,Gallion H,Comerci J,Edwards RP,Wu A,Andrade RS,Kalnicki S

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:Most precancerous lesions of the cervix are treated with surgery or ablative therapy. Chemoprevention, using natural and synthetic compounds, may intervene in the early precancerous stages of carcinogenesis and prevent the development of invasive disease. Our trial used indole-3-carbinol (I-3-C) administered ...

journal_title：Gynecologic oncology

authors： Bell MC,Crowley-Nowick P,Bradlow HL,Sepkovic DW,Schmidt-Grimminger D,Howell P,Mayeaux EJ,Tucker A,Turbat-Herrera EA,Mathis JM

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the sensitivity of sentinel node (SN) ultrastaging and to define parameters that may reduce the overall false-negative rate in women with early-stage cervical cancer. METHODS:We analyzed data from a large retrospective multicenter cohort group with FIGO stages IA-IIB cervical cancer in whom at le...

journal_title：Gynecologic oncology

authors： Cibula D,Abu-Rustum NR,Dusek L,Slama J,Zikán M,Zaal A,Sevcik L,Kenter G,Querleu D,Jach R,Bats AS,Dyduch G,Graf P,Klat J,Meijer CJ,Mery E,Verheijen R,Zweemer RP

更新日期：2012-12-01 00:00:00

abstract：:Effective cytotoxic treatment options for advanced cervical cancer are exceedingly limited. Cisplatin-based combination chemotherapy, the most commonly used cytotoxic therapy, has produced response rates ranging from 20% to 30% and overall survival of less than 10 months. Because of the minimal degree of success with ...

journal_title：Gynecologic oncology

authors： del Campo JM,Prat A,Gil-Moreno A,Pérez J,Parera M

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Chemotherapy-induced peripheral neuropathy (CIPN) presents itself as sensory peripheral neuropathy (SPN) or motor peripheral neuropathy (MPN). Our aim was to examine the course of SPN and MPN, and their impact on health-related quality of life (HRQoL) among ovarian cancer patients. METHODS:All newly diagnose...

journal_title：Gynecologic oncology

authors： Bonhof CS,Mols F,Vos MC,Pijnenborg JMA,Boll D,Vreugdenhil G,Ezendam NPM,van de Poll-Franse LV

更新日期：2018-06-01 00:00:00

abstract：:Ninety-three consecutive operative cases of myometrial invasive endometrioid adenocarcinoma of the uterus without evidence of extrauterine spread at surgery were reviewed to determine whether any histopathologic features other than those traditionally reported might predict recurrence. Recurrence was associated with t...

journal_title：Gynecologic oncology

authors： Lee KR,Vacek PM,Belinson JL

更新日期：1994-07-01 00:00:00

abstract：:Management of Stage I adenocarcinoma of the uterus includes hysterectomy, bilateral salpingo-oophorectomy, and selective paraaortic and pelvic lymphadenectomy. Postoperative radiation therapy (RT) is selectively employed in patients with histologically defined poor prognostic indicators. We attempted to identify these...

journal_title：Gynecologic oncology

authors： Malviya VK,Deppe G,Malone JM Jr,Sundareson AS,Lawrence WD

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the long-term outcomes of young early stage cervical cancer patients wishing to preserve their childbearing potential. METHODS:Data of young (aged <40 years) patients with early stage cervical cancer were prospectively collected. All patients with stage IA2, IB1 and IB2 cervical cancer were inclu...

journal_title：Gynecologic oncology

authors： Bogani G,Chiappa V,Vinti D,Somigliana E,Filippi F,Murru G,Murgia F,Martinelli F,Ditto A,Raspagliesi F

更新日期：2019-07-01 00:00:00

abstract：:One of the most prevalent potential therapeutic targets for women with endometrioid endometrial cancer (EC) is the estrogen receptor (ER)/progesterone receptor (PR) pathway. Despite a high proportion of endometrioid ECs being ER and/or PR positive, endocrine therapy is only effective in a minority of women with EC and...

journal_title：Gynecologic oncology

authors： Jerzak KJ,Duska L,MacKay HJ

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVES:Intraperitoneal (IP) chemotherapy following neoadjuvant chemotherapy (NACT) and interval tumor reductive surgery (TRS) for advanced ovarian cancer is feasible, however, the impact on disease outcomes remains unclear. We compare outcomes of patients treated with IP chemotherapy versus intravenous (IV) chemoth...

journal_title：Gynecologic oncology

authors： Bixel K,Vetter M,Davidson B,Berchuck A,Cohn D,Copeland L,Fowler JM,Havrilesky L,Lee PS,O'Malley DM,Salani R,Valea F,Alvarez Secord A,Backes F

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:This study aimed to validate the preoperative scoring system adopted in the Kanagawa Cancer Center (KCC) to stratify endometrial cancer patients for lymphadenectomy according to the risk of developing lymph node metastasis (LNM). METHODS:The records of 432 and 221 uterine cancer patients treated in the KCC a...

journal_title：Gynecologic oncology

authors： Imai K,Kato H,Katayama K,Nakanishi K,Kawano A,Iura A,Konnai K,Onose R,Hirahara F,Miyagi E

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the utility of combined positron emission tomography/computed tomography (PET/CT) for detecting recurrent epithelial ovarian cancer limited to retroperitoneal adenopathy. METHODS:Fourteen patients (median age = 53 years) with rising serum CA125 levels, and negative or equivocal conventional CT im...

journal_title：Gynecologic oncology

authors： Bristow RE,Giuntoli RL 2nd,Pannu HK,Schulick RD,Fishman EK,Wahl RL

更新日期：2005-11-01 00:00:00

abstract：:The extent to which the antigenic phenotype of human epithelial ovarian cancer changes during the course of the disease is an issue that must be addressed in order to maximize the potential of antibody-directed imaging and therapy. We have obtained tumor specimens at two separate operations from ten patients with epit...

journal_title：Gynecologic oncology

authors： Rubin SC,Finstad CL,Hoskins WJ,Federici MG,Lloyd KO,Lewis JL Jr

更新日期：1989-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to detect beta-subunit human chorionic gonadotropin (beta(h)CG) mRNA in the peripheral blood samples of patients with nonmetastatic gestational trophoblastic disease (GTD) undergoing hysterectomy. METHODS:Heparinized peripheral blood samples were obtained from four patients with non...

journal_title：Gynecologic oncology

authors： Suzuka K,Matsui H,Iitsuka Y,Sekiya S

更新日期：2002-07-01 00:00:00

abstract：:While many investigators have described the biochemical and physiological similarities between tumor cells and trophoblast cells, in this discourse we will compare primarily their leucocytes, which constitute a large portion of the tumor and its microenvironment as well as the placenta and its microenvironment. There ...

journal_title：Gynecologic oncology

authors： Beaman KD,Dambaeva S,Katara GK,Kulshrestha A,Gilman-Sachs A

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:Some authors have recommended the use of diagnostic laparoscopy as a pretreatment assessment step for conservative hormonal treatment in young women with endometrial cancer. The aim of this study was to determine the incidence of synchronous primary cancer of the endometrium and ovary in young women. METHODS...

journal_title：Gynecologic oncology

authors： Song T,Seong SJ,Bae DS,Suh DH,Kim DY,Lee KH,Lim MC,Lee TS

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:This study explores patterns of lifestyle change and whether more threatening illness perceptions are associated with lifestyle changes post-treatment for smoking, alcohol consumption and Body Mass Index (BMI) among gynecological cancer patients. METHODS:In total, 395 cancer patients (N=221 endometrial; N=17...

journal_title：Gynecologic oncology

authors： van Broekhoven MECL,de Rooij BH,Pijnenborg JMA,Vos MC,Boll D,Kruitwagen RFPM,van de Poll-Franse LV,Ezendam NPM

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:We evaluated the use of positron emission tomography (PET) with fluorine-18-labeled fluoro-2-deoxy-d-glucose (FDG) in follow-up study after radiation therapy in patients with uterine cervical carcinoma. MATERIALS AND METHODS:Thirty-two studies in 25 patients were reviewed. Twenty patients were treated with ext...

journal_title：Gynecologic oncology

authors： Sakurai H,Suzuki Y,Nonaka T,Ishikawa H,Shioya M,Kiyohara H,Katoh H,Nakayama Y,Hasegawa M,Nakano T

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Human papillomavirus type 16 variants have been described and may have different biologic activities: this has implications for the design of HPV vaccines. OBJECTIVES:The aim of this study was to see if the HPV16 variant E-G 131 can be detected in women with preinvasive disease and to consider the histologi...

journal_title：Gynecologic oncology

authors： Etherington IJ,Ellis JR,Luesley DM,Moffitt DD,Young LS

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to evaluate a modified MonoPrep2 (MP) of liquid-based cytology (LBC) to search for a less expensive alternative technique usable for screening of cervical cancers. STUDY DESIGN:Cervicovaginal direct-to-vial samples from 1218 consecutive patients were processed with the modified M...

journal_title：Gynecologic oncology

authors： Nam JH,Kim HS,Lee JS,Choi HS,Min KW,Park CS

更新日期：2004-09-01 00:00:00

abstract：:By serendipity we have had the opportunity to evaluate cis-platin-based chemotherapy in ovarian tumors of low malignant potential (LMP). Optimal (less than 1 cm residual disease) FIGO stage III ovarian carcinomas were randomly assigned to treatment with cisplatin plus cyclophosphamide with or without doxorubicin on a ...

journal_title：Gynecologic oncology

authors： Sutton GP,Bundy BN,Omura GA,Yordan EL,Beecham JB,Bonfiglio T

更新日期：1991-06-01 00:00:00

abstract：INTRODUCTION:We compare the racial and ethnic demographics of our participants with the populations where our clinics are located (Texas and British Columbia) and investigate the reasons cited for participation. METHODS:We compared the distribution of participants by race/ethnicity to numbers from the 2000 United Stat...

journal_title：Gynecologic oncology

authors： Pham B,Earle N,Rabel K,Follen M,Scheurer ME

更新日期：2007-10-01 00:00:00

abstract：:The distribution of colon--ovarian tumor antigen (COTA) and colon-specific antigen (CSA) was studied immunohistochemically in gynecologic tumors. The antigens were absent in the serous benign tumors of the ovary and in the normal ovarian tissues, whereas they were detected in some of the mucinous benign tumors. COTA a...

journal_title：Gynecologic oncology

authors： Ueda G,Shimizu C,Saito J,Tanaka Y,Inoue M,Tanizawa O

更新日期：1989-10-01 00:00:00