Synchronous primary cancers of the endometrium and ovary in young women: a Korean Gynecologic Oncology Group Study.

abstract：:This study evaluated the effects of cisplatin on 18 nerve conduction parameters of median, ulnar, peroneal, and sural nerves in relation to age, magnesium nadir, average magnesium, and magnesium replacement in gynecologic oncology patients. The 37 patients in this study received cisplatin (70 mg/m2) at 4-week interval...

journal_title：Gynecologic oncology

authors： Ashraf M,Riggs JE,Wearden S,Scotchel P

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:To assess the treatment and outcome of patients with endometrial cancer following isolated pulmonary relapse. METHODS:Between 1984 and 1996, 82 of 1109 patients undergoing surgery for primary endometrial cancer experienced a primary pulmonary recurrence, 28 of which were solitary. Median follow up of censore...

journal_title：Gynecologic oncology

authors： Dowdy SC,Mariani A,Bakkum JN,Cliby WA,Keeney GL,Podratz KC

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:The efficacy and safety of bevacizumab and docetaxel were evaluated in women who developed recurrent epithelial ovarian, fallopian, or peritoneal cancer within 12 months of platinum-based therapy. METHODS:Patients received docetaxel (40 mg/m(2)) on days 1 and 8 and bevacizumab (15 mg/kg) on day 1 of a 21-da...

journal_title：Gynecologic oncology

authors： Wenham RM,Lapolla J,Lin HY,Apte SM,Lancaster JM,Judson PL,Gonzalez-Bosquet J,Herschberger A,Havrilesky LJ,Secord AA

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Low-grade endometrial stromal sarcoma is generally an indolent tumor rich in estrogen and progesterone receptors. Objective responses to hormonal therapy, most commonly with megestrol acetate, have been reported. CASE:The patient is a 51-year-old woman who presented with low-grade endometrial stromal sarcom...

journal_title：Gynecologic oncology

authors： Maluf FC,Sabbatini P,Schwartz L,Xia J,Aghajanian C

更新日期：2001-08-01 00:00:00

abstract：:From June 1, 1984, to May 31, 1985, 98 cases of epithelial ovarian carcinomas were assessed and followed prospectively using a new murine monoclonal antibody OC 125 which detects the antigen CA 125. Serous tumors comprised 43.7% of cases, mucinous tumors 20.4%, endometrioid tumors 16%, and other epithelial tumors 19.4...

journal_title：Gynecologic oncology

authors： Altaras MM,Goldberg GL,Levin W,Bloch B,Darge L,Smith JA

更新日期：1988-05-01 00:00:00

abstract：OBJECTIVES:The role of adjuvant therapy in patients with early stage ovarian carcinoma has not been clearly defined. Most randomized trials examining this issue have not used the vigorous staging exploration accepted as today's standard. This report examines the natural history of patients after surgically documented s...

journal_title：Gynecologic oncology

authors： Le T,Krepart GV,Lotocki RJ,Heywood MS

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to examine the relationships between cyclooxygenase-2 (COX-2) expression and prognostic factors in cervical carcinomas. METHODS:We studied COX-2 expression in 53 women with cervical cancers, including 35 squamous cell carcinomas (SCCs), 1 adenosquamous cell carcinoma (ASCC), and...

journal_title：Gynecologic oncology

authors： Chen YJ,Wang LS,Wang PH,Lai CR,Yen MS,Ng HT,Yuan CC

更新日期：2003-03-01 00:00:00

abstract：:From 1973 to 1982 single-dose (0.04 mg/kg or 1.25 mg/m2), biweekly actinomycin D was used to treat 28 women with postmolar, good-prognosis trophoblastic disease. Among the 17 patients fully evaluable for response to treatment 12 were nonmetastatic (NMTD) and 5 had lung metastases (MTD). Nine NMTD patients and 5 MTD pa...

journal_title：Gynecologic oncology

authors： Schlaerth JB,Morrow CP,Nalick RH,Gaddis O Jr

更新日期：1984-09-01 00:00:00

abstract：OBJECTIVES:Sonohysterography (SHG) has been proposed as a useful tool for the surveillance of the endometrium in patients receiving tamoxifen. This study aimed to assess the value of SHG in asymptomatic patients who would have been biopsy candidates because of abnormal transvaginal ultrasound (TVUS) results. METHODS:T...

journal_title：Gynecologic oncology

authors： Bertelli G,Valenzano M,Costantini S,Rissone R,Angiolini C,Signorini A,Gustavino C

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:Evidence-based management of granulosa cell tumors of the ovary (GCT) has been not yet standardized: surgery, including fertility-sparing procedures for young women, has been traditionally the standard treatment; on the other hand, chemotherapy has been used for treatment of advanced and/or recurrent disease....

journal_title：Gynecologic oncology

authors： Mangili G,Ottolina J,Cormio G,Loizzi V,De Iaco P,Pellegrini DA,Candiani M,Giorda G,Scarfone G,Cecere SC,Frigerio L,Gadducci A,Marchetti C,Ferrandina G

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:This study describes the surgical treatment and follow-up of 213 patients with primary vulvar cancer; particular attention is given to reconstructive surgical procedures. METHODS:The clinical and pathological parameters of the patients were recorded according to standardized procedures, and the data concerni...

journal_title：Gynecologic oncology

authors： Weikel W,Hofmann M,Steiner E,Knapstein PG,Koelbl H

更新日期：2005-10-01 00:00:00

abstract：:Myometrial invasion greater than 33% negatively affects the prognosis of endometrial carcinoma. Since the endometrium is readily differentiated from myometrium via high-resolution transvaginal sonography (TVS), this prospective study was undertaken to evaluate the efficacy of TVS in determining the depth of myometrial...

journal_title：Gynecologic oncology

authors： Sahakian V,Syrop C,Turner D

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:It has been suggested that mutation of the TP53 tumor suppressor gene is involved in endometrial carcinogenesis. However, the status of p53 function in endometrial cancers has not yet been investigated in detail. METHODS:We surveyed inactivating p53 mutations in endometrial carcinomas using the yeast p53 fu...

journal_title：Gynecologic oncology

authors： Sakuragi N,Hirai A,Tada M,Yamada H,Yamamoto R,Fujimoto S,Moriuchi T

更新日期：2001-12-01 00:00:00

abstract：:A case of fatal radiation hepatitis occurring after treatment with 2200 rad given by the moving strip technique is presented. This fatality occurred in a 28-year-old woman with persistent ovarian carcinoma despite prolonged chemotherapy. Scans of the liver using computerized tomography, 99mTc sulfur colloid, and 99mTc...

journal_title：Gynecologic oncology

authors： Schacter L,Crum E,Spitzer T,Maksem J,Diwan V,Kolli S

更新日期：1986-07-01 00:00:00

abstract：OBJECTIVE:The origins and clinical significance of endosalpingiosis (ES), ectopic tubal epithelium, are not well understood. These investigations aim to characterize ES as it relates to normal fallopian tube, ovarian surface and serous neoplasms. METHODS:A retrospective review of pathology reports from all prophylacti...

journal_title：Gynecologic oncology

authors： Esselen KM,Ng SK,Hua Y,White M,Jimenez CA,Welch WR,Drapkin R,Berkowitz RS,Ng SW

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:To assess sexual function of vulvar cancer survivors who received extensive and less extensive treatment. To explore associations between sexual function and patient, disease, treatment, and psychological variables. METHODS:Sexual function (Female Sexual Function Index, FSFI), mental and physical well-being...

journal_title：Gynecologic oncology

authors： Hazewinkel MH,Laan ET,Sprangers MA,Fons G,Burger MP,Roovers JP

更新日期：2012-07-01 00:00:00

abstract：INTRODUCTION:The ability to minimize residual disease during primary cytoreductive surgery is the strongest predictor for improved overall survival in advanced ovarian cancer. But while the probability to achieve a macroscopic complete resection increases if surgery is preceded by neoadjuvant chemotherapy (NACT), survi...

journal_title：Gynecologic oncology

authors： Timmermans M,van der Hel O,Sonke GS,Van de Vijver KK,van der Aa MA,Kruitwagen RF

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:This study investigated the relationship between 13 proteins involved in DNA damage and the outcomes of patients with recurrent ovarian cancer (ROC). PATIENTS AND METHODS:Immunohistochemistry staining was performed in 114 diagnostic samples from patients with serous ROC who participated in the OVA-301 study,...

journal_title：Gynecologic oncology

authors： Monk BJ,Kaye SB,Poveda A,Herzog TJ,Aracil M,Nieto A,Badri N,Parekh TV,Tanović A,Galmarini CM

更新日期：2014-01-01 00:00:00

abstract：:Endocrine and clinicopathologic findings in a 77-year-old woman with ovarian mucinous adenofibroma of borderline malignancy are reported. The preoperative levels of testosterone, androstenedione, estrone, and estradiol in her peripheral blood were 91 ng/ml, 3.78 ng/ml, 82 pg/ml, and 35 pg/ml, respectively, abnormally ...

journal_title：Gynecologic oncology

authors： Tohya T,Mizutani H,Katabuchi H,Miyazaki K,Okamura H

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:Many studies have examined the relationship between worry and cancer screening. Due to methodological inconsistencies, results of these studies have varied and few conclusions can be made when generalizing across studies. The purpose of the current study was to better understand the worry-cancer screening rel...

journal_title：Gynecologic oncology

authors： Ruberg JL,Helm CW,Felleman BI,Helm JE,Studts JL

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Ovarian cancer is the deadliest gynecologic malignancy, yet the effects on survival of modifiable pre-diagnosis lifestyle factors, such as obesity and physical activity, remain largely unexplored. Our objective was to evaluate the effect of pre-diagnosis BMI and physical activity on ovarian cancer mortality ...

journal_title：Gynecologic oncology

authors： Zamorano AS,Hagemann AR,Morrison L,Lee JA,Liao LM,Brinton LA,Park Y,Toriola AT

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To profile long non-coding RNA (lncRNA) expression at the various anatomic sites of high-grades serous carcinoma (HGSC) and in effusion-derived exosomes. METHODS:LncRNA profiling was performed on 60 HGSC specimens, including 10 ovarian tumors, 10 solid metastases and 10 malignant effusions, as well as exosom...

journal_title：Gynecologic oncology

authors： Filippov-Levy N,Cohen-Schussheim H,Tropé CG,Hetland Falkenthal TE,Smith Y,Davidson B,Reich R

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:For many years, BRCA mutational status has only been considered as a predictor of ovarian cancer susceptibility and as a prognostic factor. Nonetheless, in the era of precision medicine, it has also become a predictive biomarker of response to platinum-based-chemotherapy and, more recently, to PARP-inhibitors...

journal_title：Gynecologic oncology

authors： Marchetti C,Minucci A,D'Indinosante M,Ergasti R,Arcieri M,Capoluongo ED,Pietragalla A,Caricato C,Scambia G,Fagotti A

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:Results of the ICON4/AGO-OVAR-2.2 trial suggest that a platinum/taxane combination provides a survival benefit in relapsed, platinum-sensitive ovarian cancer compared to platinum alone. The optimal specific combination has yet to be determined. The current study evaluates weekly docetaxel and carboplatin in t...

journal_title：Gynecologic oncology

authors： Kushner DM,Connor JP,Sanchez F,Volk M,Schink JC,Bailey HH,Harris LS,Stewart SL,Fine J,Hartenbach EM,Wisconsin Oncology Network.

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVES:Although the reported incidence of carboplatin hypersensitivity is low, its occurrence is important to characterize because of potential fatal complications. The purpose of this study was to determine the current incidence of carboplatin hypersensitivity in the ovarian cancer patients compared to other oncol...

journal_title：Gynecologic oncology

authors： Navo M,Kunthur A,Badell ML,Coffer LW 2nd,Markman M,Brown J,Smith JA

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Vulvar synovial cell sarcomas are rare, with only four previously published cases in the literature. Traditionally, the primary management for these tumors has been surgery alone. CASE:We report a case of a large vulvar synovial cell sarcoma in a 50-year-old woman treated with comprehensive combined multimo...

journal_title：Gynecologic oncology

authors： Holloway CL,Russell AH,Muto M,Albert M,Viswanathan AN

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Since 1999, patients with low risk endometrial cancer (EC) as defined by the Mayo criteria have preferably not undergone lymphadenectomy (LND) at our institution. Here we prospectively assess survival, sites of recurrence, morbidity, and cost in this low risk cohort. METHODS:Cause-specific survival (CSS) was...

journal_title：Gynecologic oncology

authors： Dowdy SC,Borah BJ,Bakkum-Gamez JN,Weaver AL,McGree ME,Haas LR,Keeney GL,Mariani A,Podratz KC

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To define a prognostic score based on pretreatment values of leucocyte, platelet and hemoglobin in locally advanced cervical cancer (LACC). MATERIAL AND METHODS:We conducted a prospective study of 238 patients for LACC with negative PET imaging in the para-aortic (PA) area and who were undergoing laparoscopi...

journal_title：Gynecologic oncology

authors： Maulard A,Chargari C,Faron M,Alwohaibi A,Leary A,Pautier P,Genestie C,Morice P,Gouy S

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To identify novel prognostic and therapeutic markers for PARP inhibitors in BRCA wild type ovarian cancer (OvCa). METHODS:BRCAness status was defined by analyzing whole-exome deep sequencing data from 220 BRCAwt OvCa cases in TCGA. Thirty-three DNA-repair genes were screened in an integrated manner for BRCA-...

journal_title：Gynecologic oncology

authors： Zhang M,Liu G,Xue F,Edwards R,Sood AK,Zhang W,Yang D

更新日期：2016-04-01 00:00:00

abstract：:The steroid receptor content of the primary endometrial cancer of 22 patients who were treated for recurrent or advanced disease has been measured and correlated with response to medroxyprogesterone acetate. No patient with a progesterone receptor (PR)-negative tumor responded and only 2 patients with PR-positive tumo...

journal_title：Gynecologic oncology

authors： Quinn MA,Cauchi M,Fortune D

更新日期：1985-07-01 00:00:00