Abstract：
:The distribution of colon--ovarian tumor antigen (COTA) and colon-specific antigen (CSA) was studied immunohistochemically in gynecologic tumors. The antigens were absent in the serous benign tumors of the ovary and in the normal ovarian tissues, whereas they were detected in some of the mucinous benign tumors. COTA and CSA were present and similarly distributed in most malignant epithelial tumors of the ovary, with their expression increasing with malignancy. Both antigens were almost completely absent in normal glands of the endometrium, but were expressed in many of the endometrial adenocarcinomas. Adenocarcinomas of the cervix were strongly positive for both antigens, and they were also detected in some of the normal cervical glands. However, no relationship was found between the expression of the two antigens and that of argyrophilia, an intestinal metaplasia.
journal_name
Gynecol Oncoljournal_title
Gynecologic oncologyauthors
Ueda G,Shimizu C,Saito J,Tanaka Y,Inoue M,Tanizawa Odoi
10.1016/0090-8258(89)90019-xsubject
Has Abstractpub_date
1989-10-01 00:00:00pages
90-2issue
1eissn
0090-8258issn
1095-6859journal_volume
35pub_type
杂志文章abstract：OBJECTIVES:The precise role of gonadotropins in the carcinogenesis of epithelial ovarian cancer remains uncertain. Recently, the haplotype of two single nucleotide polymorphisms, Thr307Ala (rs6165) and Asn680Ser (rs6166), has been described as a risk factor for ovarian cancer in Chinese women. In this study we investig...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2008.12.011
更新日期：2009-03-01 00:00:00
abstract：OBJECTIVE:Upper abdominal spreading of advanced-stage ovarian cancer often involves the diaphragm. In addition, bulky diaphragmatic tumors occasionally infiltrate the liver. Here, we describe our early experiences with a ventral liver mobilization technique to remove diaphragmatic tumors with liver involvement. METHOD...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2016.01.017
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVE:To evaluate c-erbB2 gene amplification in a series of primary uterine serous carcinoma (USC) cell lines. To assess the efficacy of AZD8055, a novel dual mTORC1/2 inhibitor against primary HER2/neu amplified vs HER2/neu not amplified USC cell lines. METHODS:Twenty-two primary USC cell lines were evaluated for...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2013.08.033
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:There are a few cases of "small cell neuroendocrine carcinoma" of the Bartholin's gland as well as Merkel cell carcinoma of the vulva reported in the gynecologic oncology literature, most with aggressive clinical behavior. Merkel cells were originally described in the epidermis with neuroendocrine properties...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2004.12.064
更新日期：2005-06-01 00:00:00
abstract：:Thirty-two patients with Stage III or IV epithelial ovarian cancer and residual tumor volumes in excess of 2 cm in diameter after initial debulking were treated with platinum and cyclophosphamide chemotherapy. Twenty-seven patients (84%) received at least six courses of chemotherapy. Six patients developed grade 3 or ...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/0090-8258(87)90296-4
更新日期：1987-06-01 00:00:00
abstract：OBJECTIVE:This study aimed to determine if there is a causal relationship between removal of the circumflex iliac nodes distal to the external iliac nodes (CINDEIN) and postoperative lower-extremity lymphedema (POLEL) after systematic lymphadenectomy in patients with cervical cancer. METHODS:A retrospective chart revi...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2015.09.007
更新日期：2015-11-01 00:00:00
abstract：:The Swedish Tumor Registries are population based. Three hundred eighty-four patients with epithelial ovarian cancer registered in the Tumor Registry of the Southeast Health Care Region during the years 1984 to 1987 were reviewed; 332 patients were eligible for survival analysis. The protocol treatment during this per...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1006/gyno.1993.1007
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Primary non-gestational choriocarcinoma of the female genital tract has been described in the ovaries and is very unusual in other genital sites. CASE:Primary non-gestational uterine cervical choriocarcinoma was diagnosed in a patient, 32, single, without previous sexual contact nor antecedent pregnancy, ad...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2005.03.045
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:Hydronephrosis can be a side effect of radical hysterectomy for cervical cancer. The incidence of clinically relevant hydronephrosis has not been studied in a large sample and the benefit of early detection of hydronephrosis is not clear. OBJECTIVE:To assess the incidence of hydronephrosis, following radica...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2011.09.010
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the utility of combined positron emission tomography/computed tomography (PET/CT) for detecting recurrent epithelial ovarian cancer limited to retroperitoneal adenopathy. METHODS:Fourteen patients (median age = 53 years) with rising serum CA125 levels, and negative or equivocal conventional CT im...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2005.06.019
更新日期：2005-11-01 00:00:00
abstract：OBJECTIVE:To profile long non-coding RNA (lncRNA) expression at the various anatomic sites of high-grades serous carcinoma (HGSC) and in effusion-derived exosomes. METHODS:LncRNA profiling was performed on 60 HGSC specimens, including 10 ovarian tumors, 10 solid metastases and 10 malignant effusions, as well as exosom...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2018.01.004
更新日期：2018-03-01 00:00:00
abstract：OBJECTIVE:While primary cisplatin-based intraperitoneal chemotherapy has been shown to favorably impact survival in small-volume residual advanced ovarian cancer, there is a need to develop strategies that improve the effectiveness of this approach. METHODS:A multi-center phase 2 trial was conducted that added intrave...
journal_title：Gynecologic oncology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ygyno.2009.04.023
更新日期：2009-08-01 00:00:00
abstract：:Pelvic washings for cytologic analysis have become an accepted diagnostic procedure in the management of endometrial carcinoma. A retrospective study was performed in 163 consecutive patients with FIGO Stage I and II endometrial carcinoma to assess the significance and value of the washings. Abnormal results were obta...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/s0090-8258(87)80008-2
更新日期：1987-09-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to analyze our experience with colorectal function preservation at the time of pelvic exenteration. METHODS:Between January 1980 and December 2001, 201 pelvic exenterations for gynecologic malignancies were performed in our hospital. Ninety-eight were supralevator exenteration...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/s0090-8258(03)00069-6
更新日期：2003-04-01 00:00:00
abstract：OBJECTIVE:This trial determined the efficacy and tolerability of sorafenib and weekly topotecan in patients with platinum-resistant ovarian cancer (OC) or primary peritoneal carcinomatosis (PPC). METHODS:Primary endpoints were maximum tolerated dose of sorafenib with weekly topotecan (phase I) and response rate (phase...
journal_title：Gynecologic oncology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ygyno.2011.08.033
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Although renal cell carcinoma (RCC) is characterized with unpredictable clinical presentation, multiple genital tract metastases are still surprising and mode of spread is obscure. CASE:We report a case of RCC metastases to uterine cervix and vagina 1 year after radical nephrectomy in a 19-year-old virgin. ...
journal_title：Gynecologic oncology
pub_type： 杂志文章,评审
doi：10.1016/j.ygyno.2005.06.004
更新日期：2005-10-01 00:00:00
abstract：OBJECTIVES:After treatment for ovarian cancer, women want to know when they will feel 'normal' again. Our objective was to document the proportions of women with high levels of physical and emotional symptoms at the end of treatment, determine if/when they return to normal and identify groups at risk of persistent symp...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2020.07.029
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:Although there have been studies that focused on the correlation between the HPV presence of pelvic lymph nodes and pathological metastasis in patients with cervical cancer, the biologic role of HPV DNA in lymph nodes still remains uncertain. We performed this study to investigate the correlation between the ...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2006.12.016
更新日期：2007-05-01 00:00:00
abstract：OBJECTIVE:To determine the outcome, complications and likelihood of requiring adjuvant therapy of patients with stage IB2 cervical cancer treated with primary radical hysterectomy and lymph node dissection. METHODS:Clinical and pathologic data between 1985 and 1999 were reviewed. Associations between clinical and path...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2004.04.016
更新日期：2004-07-01 00:00:00
abstract：:Retrospective review of sections of ovary from 50 patients with stage I, grade 1-3, epithelial ovarian carcinoma was performed to assess presence of cellular and nuclear atypia in noncancerous tissue adjacent to the primary tumor; ovarian tissue from 50 patients undergoing incidental oophorectomy was reviewed as well....
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/0090-8258(90)90075-v
更新日期：1990-09-01 00:00:00
abstract：:Management of younger patients with early stage ovarian endodermal sinus tumor who desire to have children can be a challenging problem. However, after an adequate and thorough staging procedure for the patient's tumor status, a Stage Iai endodermal sinus tumor may be treated with conservative surgery only, followed b...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/0090-8258(84)90184-7
更新日期：1984-10-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to compare the usefulness of a new universal grading system for ovarian cancer proposed by Shimizu et al. (Cancer 82 (1998), 893; Gynecol. Oncol. 70 (1998), 2) with that of the FIGO grading system as a prognostic factor of ovarian cancer. METHODS:We reviewed all paraffin-embedded ti...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/s0090-8258(03)00133-1
更新日期：2003-06-01 00:00:00
abstract：OBJECTIVE:Recent randomized controlled data suggest that neoadjuvant chemotherapy (NACT) with interval debulking (ID) may produce similar overall survival and progression free survival compared to standard primary cytoreduction followed by chemotherapy. The object of our study was to assess current patterns of care amo...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2010.06.021
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the clinicopathological features of ovarian Sertoli-Leydig cell tumors (SLCTs) and to explore the reasonable therapy. METHODS:A total of 40 cases of SLCTs were retrospectively reviewed. RESULTS:The incidence of SLCTs was 0.41%, with a median age of 28 years. All tumors were confined to one ovary...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2012.07.114
更新日期：2012-11-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to evaluate clinical manifestations, management options, and prognosis for women presenting with gestational trophoblastic tumors with vaginal metastasis. METHOD:Fifty-one patients with vaginal metastases were analyzed retrospectively between January 1985 and September 2000. Vaginal...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1006/gyno.2001.6540
更新日期：2002-03-01 00:00:00
abstract：OBJECTIVE:To estimate the frequency of cervical cytologic/histologic discrepancies in a group of obstetric patients diagnosed as HIV infected by routine prenatal screening. Also, to determine if serum CD4 levels or sexually transmitted diseases (STDs) are associated with the occurrence of preinvasive cervical disease i...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1006/gyno.1997.4683
更新日期：1997-06-01 00:00:00
abstract：OBJECTIVES:The impact of diffusion-weighted imaging (DWI) and apparent diffusion coefficients (ADCs) of MR imaging on the evaluation of residual Uterine Cervical Carcinoma after Radiation Therapy, in addition to conventional MR images. METHODS:Fourty-nine women presenting with a uterine cervical cancer were examined w...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2011.06.009
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVE:To investigate the relationship between molecular subtype, intraperitoneal (IP) disease dissemination patterns, resectability, and overall survival (OS) in advanced high-grade serous ovarian cancer (HGSOC). METHODS:Patients undergoing primary surgery for stage III-IV HGSOC at Mayo Clinic from 1994 to 2011 we...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2018.06.002
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Primary cancer of the vulva is not common, constituting only 3-5% of all gynecologic malignancies and <1% of all cancer in the female. Metastatic tumors of the vulva are even more unusual, constituting only 5-8% of all vulvar cancers. CASE:A 32-year-old female underwent total mastectomy with axillary lymph ...
journal_title：Gynecologic oncology
pub_type： 杂志文章
doi：10.1016/j.ygyno.2004.06.034
更新日期：2004-09-01 00:00:00
abstract：BACKGROUND:Protein homeostasis is a highly complex network of molecular interactions governing the health and life span of the organism. Molecular chaperones, mainly heat shock proteins (HSP) and other stress-inducible proteins abundantly expressed in multiple compartments of the cell, are major modulators of protein h...
journal_title：Gynecologic oncology
pub_type： 杂志文章,评审
doi：10.1016/j.ygyno.2009.10.078
更新日期：2010-05-01 00:00:00
