The haplotype of two FSHR polymorphisms in ovarian cancer--a potential role of ethnology in risk modification.

abstract：BACKGROUND:Obesity confers an overall increased risk for development of endometrial cancer. However there are conflicting reports regarding the effect of obesity on patients' overall and disease specific survival. The purpose of this study was to evaluate the effect of obesity on survival in women with endometrial canc...

journal_title：Gynecologic oncology

authors： Van Arsdale A,Miller DT,Kuo DY,Isani S,Sanchez L,Nevadunsky NS

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Herpes gestationis (HG) is a rare, recurrent, pruritic, vesicobullous dermatosis occurring predominantly in pregnancy and seldom in early puerperium. Reports of the association of HG with choriocarcinoma are extremely rare and this case highlights such a possible link. CASE:This case focuses on the late pos...

journal_title：Gynecologic oncology

authors： Djahansouzi S,Nestle-Kraemling C,Dall P,Bender HG,Hanstein B

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:To identify the most common causes of death and potentially modifiable risk factors in endometrial cancer patients. METHODS:745 women diagnosed with incident endometrial cancer were enrolled in a population-based study from 1991 to 1994. Participants completed structured interviews about 1 year after diagnos...

journal_title：Gynecologic oncology

authors： Lees B,Hampton JM,Trentham-Dietz A,Newcomb P,Spencer R

更新日期：2021-01-06 00:00:00

abstract：OBJECTIVE:The objective was to describe trends over time in key factors surrounding end-of-life care on a gynecologic oncology service at a tertiary cancer center. METHODS:Patients with gynecologic cancers who were hospitalized and died at our institution between 1992 and 1997 were identified using institutional datab...

journal_title：Gynecologic oncology

authors： Dalrymple JL,Levenback C,Wolf JK,Bodurka DC,Garcia M,Gershenson DM

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Chylous ascites is an uncommon complication following para-aortic lymph node dissection in the management of gynecologic malignancies. Treatment options are serial paracentesis, medium-chain triglyceride diet, total parenteral nutrition and somatostatin as conservative management and peritoneovenous shunting...

journal_title：Gynecologic oncology

authors： Boran N,Cil AP,Tulunay G,Ozgul N,Kose MF

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:We demonstrate the feasibility of detecting EC by combining minimally-invasive specimen collection techniques with sensitive molecular testing. METHODS:Prior to hysterectomy for EC or benign indications, women collected vaginal pool samples with intravaginal tampons and underwent endometrial brushing. Specim...

journal_title：Gynecologic oncology

authors： Bakkum-Gamez JN,Wentzensen N,Maurer MJ,Hawthorne KM,Voss JS,Kroneman TN,Famuyide AO,Clayton AC,Halling KC,Kerr SE,Cliby WA,Dowdy SC,Kipp BR,Mariani A,Oberg AL,Podratz KC,Shridhar V,Sherman ME

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:Secreted protein, acidic and rich in cysteine (SPARC), is a matricellular protein that modulates cell adhesion and growth. It is thought to play a decisive role in tissue remodeling and angiogenesis. Alterations in SPARC expression have been observed in a variety of solid tumors; however, no consistent patter...

journal_title：Gynecologic oncology

authors： Paley PJ,Goff BA,Gown AM,Greer BE,Sage EH

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to show the learning experience of the employment of laparoscopic lymphadenectomy followed by a Schauta operation to treat patients with cervical carcinoma at a university hospital and to evaluate the feasibility, complications, hospital stay, delay in return to work, and overall su...

journal_title：Gynecologic oncology

authors： Sardi J,Vidaurreta J,Bermúdez A,di Paola G

更新日期：1999-12-01 00:00:00

abstract：:PARP inhibitors (PARPi) have shown have activity in the treatment of ovarian cancer. Previous studies documented activity in patients with germline (gBRCA) and tumor (tBRCA) BRCA mutations (BRCAm) for treatment in lieu of chemotherapy as well as in recurrent ovarian cancer as maintenance therapy. The recent data from ...

journal_title：Gynecologic oncology

authors： Pothuri B,O'Cearbhaill R,Eskander R,Armstrong D

更新日期：2020-10-01 00:00:00

abstract：:A 65-year-old woman had a total abdominal hysterectomy and bilateral salpingo-oophorectomy through a Pfannenstiel incision for a Stage Ib, Grade 2 endometrial adenocarcinoma with extension to the middle third of the myometrium. No adjuvant treatment was given. She presented 7 years later with a large suprapubic mass a...

journal_title：Gynecologic oncology

authors： Kotwall CA,Kirkbride P,Zerafa AE,Murray D

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVE:To investigate whether alteration of BRCA1 tumor suppressor gene occurs in sporadic endometrial carcinomas. METHODS:Genomic DNAs were prepared from 33 consecutively collected endometrial carcinoma tissues for BRCA1 mutational analysis. To screen for BRCA1 mutation, polymerase chain reaction (PCR) amplificati...

journal_title：Gynecologic oncology

authors： Liu FS,Ho ES,Shih RT,Shih A

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and biological effects of the gemcitabine/tanespimycin combination in patients with advanced ovarian and peritoneal cancer. To assess the effect of tanespimycin on tumor cells, levels of the chaperone proteins HSP90 and HSP70 were examined in peripheral blood mononuclear cells (PBMC) ...

journal_title：Gynecologic oncology

authors： Hendrickson AE,Oberg AL,Glaser G,Camoriano JK,Peethambaram PP,Colon-Otero G,Erlichman C,Ivy SP,Kaufmann SH,Karnitz LM,Haluska P

更新日期：2012-02-01 00:00:00

abstract：PURPOSE:The MDS1 and EVI1 complex locus (MECOM) at 3q26 gives rise to several alternatively spliced transcripts implicated in leukemic oncogenesis. Overexpression of EVI1 in ovarian cancer has led to a proposed oncogenic role. Our objective was to evaluate the therapeutic potential of EVI1 and EVI1s (also known as Delt...

journal_title：Gynecologic oncology

authors： Jazaeri AA,Ferriss JS,Bryant JL,Dalton MS,Dutta A

更新日期：2010-08-01 00:00:00

abstract：:The oncogene specific mRNA of c-erbB-2 was detected by the S1 nuclease protection assay in 95 ovarian cancer specimens. In 79 primary carcinomas, we found 16 (20%) with strong expression, 13 (17%) with weak expression, 4 (5%) with very weak expression, and 46 (58%) with no expression. In 3 of 16 recurrencies (19%) a s...

journal_title：Gynecologic oncology

authors： Tanner B,Kreutz E,Weikel W,Meinert R,Oesch F,Knapstein PG,Becker R

更新日期：1996-08-01 00:00:00

abstract：PURPOSE:To evaluate the effectiveness of bevacizumab with single-agent chemotherapy for platinum-resistant ovarian cancer in a real-world setting. PATIENTS AND METHODS:We enrolled recurrent platinum-resistant ovarian cancer patients from 27 institutions. All had received bevacizumab with single-agent chemotherapy (wee...

journal_title：Gynecologic oncology

authors： Lee JY,Park JY,Park SY,Lee JW,Kim JW,Kim YB,Jeong DH,Lee KB,Kim TH,Lee IH,Choi MC,Kim KH,Kim YM,Lee YJ,Kang S,KGOG Investigators.,Pujade-Lauraine E

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Vulvar synovial cell sarcomas are rare, with only four previously published cases in the literature. Traditionally, the primary management for these tumors has been surgery alone. CASE:We report a case of a large vulvar synovial cell sarcoma in a 50-year-old woman treated with comprehensive combined multimo...

journal_title：Gynecologic oncology

authors： Holloway CL,Russell AH,Muto M,Albert M,Viswanathan AN

更新日期：2007-01-01 00:00:00

abstract：:Ninety-three consecutive operative cases of myometrial invasive endometrioid adenocarcinoma of the uterus without evidence of extrauterine spread at surgery were reviewed to determine whether any histopathologic features other than those traditionally reported might predict recurrence. Recurrence was associated with t...

journal_title：Gynecologic oncology

authors： Lee KR,Vacek PM,Belinson JL

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:To describe our early experience with robotic-assisted laparoscopy for extraperitoneal para-aortic lymphadenectomy up to the left renal vein, including Da Vinci robot positioning. METHODS:Six patients underwent robotic-assisted laparoscopy using the Da Vinci apparatus. The patients included a man with a pT2 ...

journal_title：Gynecologic oncology

authors： Narducci F,Lambaudie E,Houvenaeghel G,Collinet P,Leblanc E

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:Reduced Selenium-Binding Protein 1 (SELENBP1) expression was recently shown in multiple cancers. There is little information on the expression and function of SELENBP1 in cancer progression. In order to develop a better understanding of the role of SELENBP1 in ovarian cancer, our objective was to determine if...

journal_title：Gynecologic oncology

authors： Stammer K,Edassery SL,Barua A,Bitterman P,Bahr JM,Hales DB,Luborsky JL

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:The mTOR inhibitor, temsirolimus, has clinical activity in the treatment of gynecologic malignancies, particularly endometrial cancer. We sought to determine the tolerability of the combination of weekly topotecan with weekly temsirolimus. METHODS:Women with a history of advanced or recurrent gynecologic mal...

journal_title：Gynecologic oncology

authors： Temkin SM,Yamada SD,Fleming GF

更新日期：2010-06-01 00:00:00

abstract：:We describe a case in which the first recurrence of a cervical carcinoma presented as cardiac tamponade with circulatory collapse. We discuss the hemodynamics, clinical appearance, and management of metastatic-associated cardiac tamponade. ...

journal_title：Gynecologic oncology

authors： Rudoff J,Percy R,Benrubi G,Ostrowski ML

更新日期：1989-08-01 00:00:00

abstract：:Over a 7-year period from 1987 to 1994, 120 patients consecutive patients with FIGO stage IB invasive cervical cancer who underwent type 3 radical abdominal hysterectomy and bilateral pelvic lymphadenectomy had either Jackson-Pratt closed-suction drainage (Group 1, patients 1-60) or no drainage (Group 2, patients 61-1...

journal_title：Gynecologic oncology

authors： Patsner B

更新日期：1995-05-01 00:00:00

abstract：OBJECTIVE:Most guidelines advise no adjuvant radiotherapy in vulvar squamous cell carcinoma and a single occult intracapsular lymph node metastasis. However, several recent studies have questioned the validity of this recommendation. The aim of this study was to analyze the groin recurrence rate in patients with a sing...

journal_title：Gynecologic oncology

authors： van der Velden J,Pleunis N,Barlow E,Zijlmans H,de Hullu J,Hacker NF,Fons G

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:Although the reported incidence of carboplatin hypersensitivity is low, its occurrence is important to characterize because of potential fatal complications. The purpose of this study was to determine the current incidence of carboplatin hypersensitivity in the ovarian cancer patients compared to other oncol...

journal_title：Gynecologic oncology

authors： Navo M,Kunthur A,Badell ML,Coffer LW 2nd,Markman M,Brown J,Smith JA

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between molecular subtype, intraperitoneal (IP) disease dissemination patterns, resectability, and overall survival (OS) in advanced high-grade serous ovarian cancer (HGSOC). METHODS:Patients undergoing primary surgery for stage III-IV HGSOC at Mayo Clinic from 1994 to 2011 we...

journal_title：Gynecologic oncology

authors： Torres D,Wang C,Kumar A,Bakkum-Gamez JN,Weaver AL,McGree ME,Konecny GE,Goode EL,Cliby WA

更新日期：2018-08-01 00:00:00

abstract：:From 1978 to 1982, 49 patients with intraepithelial neoplasia in the vulvar region were included in a prospective investigation. The main purpose was to evaluate the effect of treatment by local excision with a free margin of 2 mm and to estimate the importance of colposcopy. In 28% of the patients, the disease recurr...

journal_title：Gynecologic oncology

authors： Andreasson B,Bock JE

更新日期：1985-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the utility of amiodarone and its derivative dronedarone as novel drug repositioning candidates in EOC and to determine the potential pathways targeted by these drugs. METHODS:Drug-predict bioinformatics platform was used to assess the utility of amiodarone as a novel drug-repurposing candidate i...

journal_title：Gynecologic oncology

authors： Belur Nagaraj A,Joseph P,Kovalenko O,Wang Q,Xu R,DiFeo A

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVES:We aimed to determine the sentinel lymph node detection rates, accuracy in predicting the status of lymph node metastasis, and if pathologic ultrastaging improves the detection of micrometastases and isolated tumor cells at the time of primary surgery for cervical cancer. METHODS:A prospective, non-randomiz...

journal_title：Gynecologic oncology

authors： Diaz JP,Gemignani ML,Pandit-Taskar N,Park KJ,Murray MP,Chi DS,Sonoda Y,Barakat RR,Abu-Rustum NR

更新日期：2011-03-01 00:00:00

abstract：:From 1980 to 1987, 30 patients with FIGO clinical Stage II carcinoma of the endometrium were treated with 5000 cGy preoperative pelvic radiation therapy at Thomas Jefferson University Hospital. Patients with gross cervical disease received additional intracavitary irradiation with a tandem and ovoids for a combined to...

journal_title：Gynecologic oncology

authors： Reisinger SA,Staros EB,Feld R,Mohiuddin M,Lewis GC

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVE:Understanding the factors that contribute to mortality and survival is central to health outcome research. The purpose of this study was to investigate the following: (1) differences in survival status by ethnicity and neighborhood median income level; and (2) individual- and neighborhood-level factors influe...

journal_title：Gynecologic oncology

authors： Lim JW,Ashing-Giwa KT

更新日期：2011-04-01 00:00:00