Alterations in SPARC and VEGF immunoreactivity in epithelial ovarian cancer.

abstract：:Two patients with vulvar carcinoma are reported who were treated with internal iliac transcatheter arterial embolization and radiotherapy. Patient 1 had T3N3M0 vulvar carcinoma. The lesion remaining after radiotherapy was treated by bilateral internal iliac arterial embolization. Vulvectomy was then performed, and the...

journal_title：Gynecologic oncology

authors： Harima Y,Shiraishi T,Harima K,Tanaka Y

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:To correlate findings on pathologic examination of loop electroexcisional procedure (LEEP) or cone biopsy specimens with residual disease in radical hysterectomy specimens in patients with stage IA2 cervical cancer to determine whether a subset of such patients may be eligible for conservative, fertility-spar...

journal_title：Gynecologic oncology

authors： Suri A,Frumovitz M,Milam MR,dos Reis R,Ramirez PT

更新日期：2009-01-01 00:00:00

abstract：:Fifty patients with cervical cancer were treated with radical hysterectomy and lymphadenectomy followed by postoperative radiation therapy for high risk factors (nodal metastases, lymphvascular space invasion, close or involved margins) at the University of Alabama at Birmingham Medical Center from 1969 to 1984. Fifte...

journal_title：Gynecologic oncology

authors： Barter JF,Soong SJ,Shingleton HM,Hatch KD,Orr JW Jr

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:The hepatocyte growth factor (HGF) receptor c-Met plays an important role in tumor dissemination by activating mitogenic signaling pathways. The goal of this study was to investigate immunohistochemical (IHC) staining patterns of HGF and c-Met in endometrioid endometrial cancer (EC) and uterine serous cancer ...

journal_title：Gynecologic oncology

authors： Bishop EA,Lengyel ER,Yamada SD,Montag A,Temkin SM

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Diaphragm involvement by ovarian cancer is often considered to be a major obstacle to successful cytoreductive surgery. Lack of evidence of survival benefit, concerns over safety and lack of experience are common justifications for this belief. In this study, we sought to evaluate the therapeutic value of di...

journal_title：Gynecologic oncology

authors： Aletti GD,Dowdy SC,Podratz KC,Cliby WA

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess the impact of surgical complexity on postoperative complications and mortality, according to patient's frailty (mFI) following surgery for ovarian cancer. METHODS:Patients undergoing cytoreductive surgery for ovarian cancer from 2008 to 2018 were identified from our databa...

journal_title：Gynecologic oncology

authors： Di Donato V,Di Pinto A,Giannini A,Caruso G,D'Oria O,Tomao F,Fischetti M,Perniola G,Palaia I,Muzii L,Benedetti Panici P

更新日期：2020-09-04 00:00:00

abstract：OBJECTIVE(S):To determine whether antibiotic treatment (ABX) during platinum chemotherapy (PC) for epithelial ovarian cancer (EOC) impacts progression-free survival (PFS) and overall survival (OS). STUDY DESIGN:Retrospective single institution cohort study in women with newly diagnosed stage III/IV EOC (n = 424) who u...

journal_title：Gynecologic oncology

authors： Chambers LM,Kuznicki M,Yao M,Chichura A,Gruner M,Reizes O,Debernardo R,Rose PG,Michener C,Vargas R

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:In the present study (EDiTH III study), the genotype-specific prevalence of HPV in low-grade squamous intraepithelial lesions (LSIL) was estimated to predict the potential benefit of HPV vaccination in France. This prevalence was compared to that previously reported in France in high-grade cervical intraepit...

journal_title：Gynecologic oncology

authors： Prétet JL,Jacquard AC,Saunier M,Clavel C,Dachez R,Gondry J,Pradat P,Soubeyrand B,Leocmach Y,Mougin C,Riethmuller D,EDiTH study group.

更新日期：2008-08-01 00:00:00

abstract：INTRODUCTION:Extrarenal Wilms' tumors are rare, with only 55 well-documented cases in the literature and only 4 confined to the uterus. A fifth case along with review of the current literature is presented. CASE:A 13-year-old girl presented with a 2-month history of irregular vaginal spotting. A 6.5 x 4.5 x 2.5-cm pol...

journal_title：Gynecologic oncology

authors： Babin EA,Davis JR,Hatch KD,Hallum AV 3rd

更新日期：2000-01-01 00:00:00

abstract：:Between 1975 and 1989, 896 patients were treated for endometrial carcinoma at the Massachusetts General Hospital. Thirty patients were identified from the tumor registry as having uterine papillary serous carcinomas. The survival for all patients and for groups of patients stratified on clinical and pathological param...

journal_title：Gynecologic oncology

authors： Kato DT,Ferry JA,Goodman A,Sullinger J,Scully RE,Goff BA,Fuller AF Jr,Rice LW

更新日期：1995-12-01 00:00:00

abstract：:cis-Platinum is a chemotherapeutic agent with benefits often limited by the severe gastrointestinal reactions it produces in nearly all patients. Persistent anorexia, nausea, and vomiting may continue for days after therapy and are poorly controlled by conventional antiemetics. Patients at times refuse continuation of...

journal_title：Gynecologic oncology

authors： Benrubi GI,Norvell M,Nuss RC,Robinson H

更新日期：1985-07-01 00:00:00

abstract：:For the past several years, all women with epithelial ovarian cancer have been treated identically, whether in a clinical trial or off protocol. Over the past decade, we have come to appreciate the magnitude of the heterogeneity of ovarian cancer. The development of the binary grading system for serous carcinoma was a...

journal_title：Gynecologic oncology

authors： Romero I,Sun CC,Wong KK,Bast RC Jr,Gershenson DM

更新日期：2013-09-01 00:00:00

abstract：:A patient with malignant struma ovarii who had elevated thyroglobulin levels at the time of her original surgery was diagnosed with recurrence on the basis of progressive thyroglobulin level elevation while on thyroid suppressive therapy. Subsequent treatment with therapeutic doses of iodine-137 resulted in normalizat...

journal_title：Gynecologic oncology

authors： Rose PG,Arafah B,Abdul-Karim FW

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:Describing the pattern of and reasons for post-operative tumor residuals in patients with advanced epithelial ovarian cancer (AOC) operated in a specialized gynecologic cancer center following a strategy of maximum upfront debulking followed by systemic chemotherapy. METHODS:All consecutive AOC-patients trea...

journal_title：Gynecologic oncology

authors： Heitz F,Harter P,Alesina PF,Walz MK,Lorenz D,Groeben H,Heikaus S,Fisseler-Eckhoff A,Schneider S,Ataseven B,Kurzeder C,Prader S,Beutel B,Traut A,du Bois A

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:Recombinant epoetin alfa and darbepoetin alfa (r-HuEPO) have been shown to be safe and effective treatments for anemia, but recent reports have suggested an increased risk of thromboembolic events when these agents are used to treat chemotherapy-induced anemia among patients with breast or ovarian cancer. We...

journal_title：Gynecologic oncology

authors： Westin SN,Skinner EN,Jonsson Funk M,Gehrig PM,Van Le L

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVES:To clarify the anatomy necessary for the nerve sparing Okabayashi's radical hysterectomy, we meticulously separated the blood vessels and connective tissues to preserve the pelvic splanchnic nerve, the hypogastric nerve, and the bladder branch of the inferior hypogastric plexus under magnification (x2.5) dur...

journal_title：Gynecologic oncology

authors： Fujii S,Takakura K,Matsumura N,Higuchi T,Yura S,Mandai M,Baba T,Yoshioka S

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:Ovarian cancer is the leading cause of death from gynecologic malignancies in the Western world. Fibroblast growth factor receptor (FGFR) signaling has been implicated to play a role in ovarian tumorigenesis. Mutational activation of one member of this receptor family, FGFR2, is a frequent event in endometrio...

journal_title：Gynecologic oncology

authors： Byron SA,Gartside MG,Wellens CL,Goodfellow PJ,Birrer MJ,Campbell IG,Pollock PM

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:This study was undertaken to determine the incidence and distribution of the location of benign müllerian inclusions in pelvic and paraaortic lymph nodes. METHODS:A total of 114 patients operated on for gynecologic malignancy between 1995 and 1998 underwent surgery including systematic pelvic (n = 114) or pe...

journal_title：Gynecologic oncology

authors： Reich O,Tamussino K,Haas J,Winter R

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVES:We assessed neoadjuvant intraarterial chemotherapy (NAC) followed by radical hysterectomy and/or radiotherapy in patients with locally advanced cervical cancer. METHODS:Over 5 years, 48 consecutive women with International Federation of Gynecology and Obstetrics stage IIb-IVa cervical cancer were enrolled. ...

journal_title：Gynecologic oncology

authors： Sugiyama T,Nishida T,Hasuo Y,Fujiyoshi K,Yakushiji M

更新日期：1998-05-01 00:00:00

abstract：:Fourteen patients with refractory or metastatic adenocarcinoma of the endometrium were treated with continuous infusion vinblastine. No patient had a response. One patient had stable disease. Although well tolerated, vinblastine sulfate given by this method has no activity in this malignancy. ...

journal_title：Gynecologic oncology

authors： Kavanagh JJ,Saul PB,Wharton JT,Rutledge FN

更新日期：1987-02-01 00:00:00

abstract：:Twenty-three evaluable patients with refractory epithelial ovarian cancer were treated with bisantrene (CL216,942). The drug was given as a single-dose injection every 3 weeks. One patient (4%) showed a partial response. The compound thus has limited activity against this malignancy. ...

journal_title：Gynecologic oncology

authors： Kavanagh JJ,Gershenson DM,Saul PB,Copeland LJ

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVES:We previously reported a 10% rate of catheter complications, including inflow obstruction and infection, using a fenestrated catheter to administer intraperitoneal (i.p.) chemotherapy for ovarian cancer. Because of recent reports of higher rates of catheter complications, we performed this study to update ou...

journal_title：Gynecologic oncology

authors： Black D,Levine DA,Nicoll L,Chou JF,Iasonos A,Brown CL,Sonoda Y,Chi DS,Leitao MM,Abu-Rustum NR,Ferguson SE,Barakat RR

更新日期：2008-04-01 00:00:00

abstract：:A 75-year-old Japanese woman, who had an enlarged uterus and two nodules on the anterior vaginal wall, underwent wide excision of the anterior vaginal wall, bilateral inguinal lymphadenectomy, modified radical hysterectomy, and pelvic lymph node dissection. Her serum level of 5-S-cysteinyldopa (5-S-CD) was elevated, b...

journal_title：Gynecologic oncology

authors： Suenaga Y,Katabuchi H,Okamura H,Kageshita T,Ono T

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:While primary cisplatin-based intraperitoneal chemotherapy has been shown to favorably impact survival in small-volume residual advanced ovarian cancer, there is a need to develop strategies that improve the effectiveness of this approach. METHODS:A multi-center phase 2 trial was conducted that added intrave...

journal_title：Gynecologic oncology

authors： Smith HO,Moon J,Wilczynski SP,Tiersten AD,Hannigan EV,Robinson WR,Rivkin SE,Anderson GL,Liu PY,Markman M

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the hospital and patient factors associated with robotic surgery for endometrial cancer in the United States. METHODS:Data was obtained from the Nationwide Inpatient Sample from the year 2010. Chi-squared and multivariate analyses were used for statistical analysis. RESULTS:Of the 6560 endometri...

journal_title：Gynecologic oncology

authors： Chan JK,Gardner AB,Taylor K,Blansit K,Thompson CA,Brooks R,Yu X,Kapp DS

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVES:In this study we evaluated changes in serum Müllerian inhibiting substance (MIS) concentration in a large number of patients with granulosa cell tumors (GCT) to determine whether MIS is elevated at the time of presentation and whether MIS is an index of successful surgical resection and management of recurre...

journal_title：Gynecologic oncology

authors： Lane AH,Lee MM,Fuller AF Jr,Kehas DJ,Donahoe PK,MacLaughlin DT

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:To determine the prognostic significance of the 2002 revisions of the American Joint Committee on Cancer (AJCC) Staging System for cutaneous melanoma in melanoma of the vulva and review the current surgical utilized for treatment of this neoplasm. METHODS:Demographic, surgical and outcomes data were obtained...

journal_title：Gynecologic oncology

authors： Moxley KM,Fader AN,Rose PG,Case AS,Mutch DG,Berry E,Schink JC,Kim CH,Chi DS,Moore KN

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Although most patients at high risk of Gestational Trophoblastic Neoplasia (GTN) respond to standard treatments, there is a group of patients that will die because of it. The use of new single or combination drugs in this population has become a priority. CASE REPORT:We present the case of a relapsed high r...

journal_title：Gynecologic oncology

authors： Bianconi M,Jankilevich G,Otero S,Nassif J,Storino C

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:Current therapy for cervical cancer includes radiation therapy. Retinoic acid (RA) can increase the sensitivity of cervical cancer cell lines to radiation. The mechanism of this sensitization may not involve the p53 protein because the human papillomavirus (HPV) E6 protein, which is present in the majority of...

journal_title：Gynecologic oncology

authors： Tillmanns TD,Kamelle SA,Guruswamy S,Gould NS,Rutledge TL,Benbrook DM

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the sensitivity of sentinel node (SN) ultrastaging and to define parameters that may reduce the overall false-negative rate in women with early-stage cervical cancer. METHODS:We analyzed data from a large retrospective multicenter cohort group with FIGO stages IA-IIB cervical cancer in whom at le...

journal_title：Gynecologic oncology

authors： Cibula D,Abu-Rustum NR,Dusek L,Slama J,Zikán M,Zaal A,Sevcik L,Kenter G,Querleu D,Jach R,Bats AS,Dyduch G,Graf P,Klat J,Meijer CJ,Mery E,Verheijen R,Zweemer RP

更新日期：2012-12-01 00:00:00