Preoperative pathologic findings associated with residual disease at radical hysterectomy in women with stage IA2 cervical cancer.

abstract：:Progress has been made in identifying the molecular changes that occur in ovarian carcinoma; still our understanding of these changes and their interactions remains incomplete. In the present study the authors examined the expression of retinoblastoma protein, a tumor suppressor protein, in a spectrum of ovarian epith...

journal_title：Gynecologic oncology

authors： Niemann TH,Trgovac TL,McGaughy VR,Lewandowski GS,Copeland LJ

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:To determine whether single agent chemotherapy with intramuscular methotrexate 50mg administered on days 1, 3, 5, and 7 and oral folinic acid 15mg administered on days 2, 4, 6, and 8 in 2 weekly cycles (IM MTX/FA) is an effective treatment regimen for patients with low risk gestational choriocarcinoma. METHO...

journal_title：Gynecologic oncology

authors： Taylor F,Short D,Winter MC,Tidy J,Savage PM,Sarwar N,Hancock BW,Seckl MJ,Coleman RE

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Survivorship and quality of life issues are becoming increasingly relevant in endometrial cancer as a result of the marked increase in incidence of the disease combined with excellent and improving long term survival. OBJECTIVE:The purpose of this study was to evaluate the effect of obesity on quality of li...

journal_title：Gynecologic oncology

authors： Smits A,Lopes A,Das N,Bekkers R,Galaal K

更新日期：2014-01-01 00:00:00

abstract：:The extent to which the antigenic phenotype of human epithelial ovarian cancer changes during the course of the disease is an issue that must be addressed in order to maximize the potential of antibody-directed imaging and therapy. We have obtained tumor specimens at two separate operations from ten patients with epit...

journal_title：Gynecologic oncology

authors： Rubin SC,Finstad CL,Hoskins WJ,Federici MG,Lloyd KO,Lewis JL Jr

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Radical vaginal trachelectomy (RVT) is an acceptable approach when applied toward a select group of patients with early stage cervical carcinoma. It is less invasive, can maintain fertility, and can be ideal in patients with significant comorbid factors compared to abdominal approaches. A small subset of pat...

journal_title：Gynecologic oncology

authors： Mendez LE,Penalver M,McCreath W,Bejarano P,Angioli R

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:Although there have been studies that focused on the correlation between the HPV presence of pelvic lymph nodes and pathological metastasis in patients with cervical cancer, the biologic role of HPV DNA in lymph nodes still remains uncertain. We performed this study to investigate the correlation between the ...

journal_title：Gynecologic oncology

authors： Lee YS,Rhim CC,Lee HN,Lee KH,Park JS,Namkoong SE

更新日期：2007-05-01 00:00:00

abstract：:The Cavitron Ultrasonic Surgical Aspirator (CUSA) can be used to fragment and aspirate tissue precisely. The CUSA was utilized as an adjunctive procedure to standard operative techniques to optimally debulk 11 women with advanced epithelial carcinoma of the ovary. No significant intraoperative or postoperative complic...

journal_title：Gynecologic oncology

authors： Deppe G,Malviya VK,Malone JM Jr

更新日期：1988-09-01 00:00:00

abstract：OBJECTIVES:Six cycles of consolidation chemotherapy have become the standard for ovarian cancer treatment regimen following primary cytoreduction, yet with neoadjuvant chemotherapy (NAC), only 3 consolidation cycles are used. This study examines the effects of number of chemotherapy cycles in women with ovarian cancer ...

journal_title：Gynecologic oncology

authors： Altman AD,McGee J,May T,Lane K,Lu L,Xu W,Ghatage P,Rosen B

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Although most patients at high risk of Gestational Trophoblastic Neoplasia (GTN) respond to standard treatments, there is a group of patients that will die because of it. The use of new single or combination drugs in this population has become a priority. CASE REPORT:We present the case of a relapsed high r...

journal_title：Gynecologic oncology

authors： Bianconi M,Jankilevich G,Otero S,Nassif J,Storino C

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVES:To evaluate the CINtec PLUS assay (mtm laboratories), a new immunocytochemical method for the simultaneous detection of p16(INK4a) and Ki-67, in liquid-based cervico-vaginal cytology, investigating the association of the dual staining with HPV infection and genotyping as well as cytological and histological ...

journal_title：Gynecologic oncology

authors： Donà MG,Vocaturo A,Giuliani M,Ronchetti L,Rollo F,Pescarmona E,Carosi M,Vocaturo G,Benevolo M

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To determine whether squamous cervical cancers exhibit mutations or deletions in MHC class I genes or transport-associated protein (TAP) genes. METHODS:Polymerase chain reaction based protocols were used to examine HLA class I and TAP genes in a panel of cervical tumours, using DNA from corresponding blood s...

journal_title：Gynecologic oncology

authors： Fowler NL,Frazer IH

更新日期：2004-03-01 00:00:00

abstract：:In order to determine the efficacy and toxicity of the gonadotrophin-releasing hormone agonist Leuprolide in the management of patients with recurrent or metastatic endometrial cancer, we performed a phase II study. Patients were included if there was clinical or radiological documentation of bidimensionally measurabl...

journal_title：Gynecologic oncology

authors： Covens A,Thomas G,Shaw P,Ackerman I,Osborne R,Lukka H,Carey M,Franssen E,Roche K

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:The presence of cardiac metastasis from cervical carcinoma is extremely rare. The diagnosis is made almost exclusively postmortem. There are few cases of premortem diagnosis, and it is believed that when cardiac metastasis are found in vivo, the prognosis is extremely poor. Due to the rarity of this conditio...

journal_title：Gynecologic oncology

authors： Lemus JF,Abdulhay G,Sobolewski C,Risch VR

更新日期：1998-06-01 00:00:00

abstract：:This commentary is presenting opinions and advice on mentorship in the field of gynecologic oncology. Eleven academic gynecologic oncologists from across the country were interviewed and their thoughts about mentorship were recorded with recurring themes and ideas described in this commentary. Trust, respect, and mutu...

journal_title：Gynecologic oncology

authors： Boitano TKL,Chi DS,Copeland LJ,Straughn JM Jr

更新日期：2021-01-27 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine the prevalence of high-risk oncogenic human papillomaviruses (HPVs) in malignant lesions from Hong Kong Chinese women with carcinomas of the upper genital tract. METHODS:The presence of high-risk HPVs in 55 cases of endometrial adenocarcinomas and 60 cases of primary ep...

journal_title：Gynecologic oncology

authors： Ip SM,Wong LC,Xu CM,Cheung AN,Tsang PC,Ngan HY

更新日期：2002-10-01 00:00:00

abstract：:Fourteen patients underwent surgical debulking of diaphragmatic metastases as part of cytoreductive surgery for advanced ovarian epithelial cancer from 1983 to 1984. The surgical technique is described. Morbidity from this approach was not excessive in this small series of patients. It is suggested that this technique...

journal_title：Gynecologic oncology

authors： Deppe G,Malviya VK,Boike G,Hampton A

更新日期：1986-06-01 00:00:00

abstract：OBJECTIVE:Human papillomavirus (HPV) infection play a significant role in cervical carcinogenesis, and HPV oncoprotein E7 has important functions in the formation and maintenance of cervical cancers. Interleukin-12 (IL-12) has been reported to induce cellular immune responses, and has also been demonstrated to suppress...

journal_title：Gynecologic oncology

authors： Jin HS,Park EK,Lee JM,NamKoong SE,Kim DG,Lee YJ,Jun HJ,Han BD,Bae SM,Ahn WS

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:No residual tumor as result of primary surgery in advanced ovarian cancer is known as one of the most important prognostic factors. PURPOSE:To evaluate the impact of different prognostic factors for surgical outcome and to evaluate the impact of surgical outcome on survival. METHODS:Surgical data as well a...

journal_title：Gynecologic oncology

authors： Wimberger P,Lehmann N,Kimmig R,Burges A,Meier W,Du Bois A,Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group.

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:The first-line chemotherapy for ovarian cancer is based on a combination of platinum and taxane. To date, no reliable predictive biomarker has been recognized that is capable of identifying patients with pre-existing resistance to these agents. Here, we have established an integrated database and identified t...

journal_title：Gynecologic oncology

authors： Fekete JT,Ősz Á,Pete I,Nagy GR,Vereczkey I,Győrffy B

更新日期：2020-03-01 00:00:00

abstract：:The thoroughness of cytoreductive surgery is the largest contributor to survival for patients with advanced ovarian and primary peritoneal carcinoma. For many years the surgery undertaken by Gynaecologic Oncologists has been tailored to match their surgical training. Future surgical training of Gynaecologic Oncologist...

journal_title：Gynecologic oncology

authors： Crandon AJ,Obermair A

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:New treatment options for advanced and recurrent endometrial carcinoma (EC) are necessary. Epidemiological studies showed that diabetic patients using metformin have reduced risks of endometrial cancer (EC) incidence. Moreover, pre- and clinical studies demonstrated an antitumor effect by metformin, with and...

journal_title：Gynecologic oncology

authors： Schrauwen S,Coenegrachts L,Cattaneo A,Hermans E,Lambrechts D,Amant F

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:This study was undertaken to determine the incidence and distribution of the location of benign müllerian inclusions in pelvic and paraaortic lymph nodes. METHODS:A total of 114 patients operated on for gynecologic malignancy between 1995 and 1998 underwent surgery including systematic pelvic (n = 114) or pe...

journal_title：Gynecologic oncology

authors： Reich O,Tamussino K,Haas J,Winter R

更新日期：2000-08-01 00:00:00

abstract：:Background. Reports of supradiaphragmatic involvement of lymph nodes by serous borderline ovarian tumors are rare. Case. We describe the finding of metastatic tumor involving an internal mammary lymph node in a 74-year-old patient with serous borderline ovarian tumor. The positive lymph node was found incidentally dur...

journal_title：Gynecologic oncology

authors： Chamberlin MD,Eltabbakh GH,Mount SL,Leavitt BJ

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:This study's objective was to quantify the impact (utility) of common complications of early cervical cancer treatment on quality of life (QOL). Utilities assigned by survivors were compared to those assigned by providers. METHODS:30 survivors of early cervical cancer identified from our Tumor Registry and 1...

journal_title：Gynecologic oncology

authors： Einstein MH,Rash JK,Chappell RJ,Swietlik JM,Hollenberg JP,Connor JP

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:Ovarian cancer is most frequently diagnosed at a late stage with a poor prognosis. No markers for early diagnosis have been established. Aberrantly methylated DNA appears as a promising molecular cancer marker. The aim of this study was to analyze the methylation status of the proapoptotic cancer related gene...

journal_title：Gynecologic oncology

authors： Häfner N,Diebolder H,Jansen L,Hoppe I,Dürst M,Runnebaum IB

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVES:Insomnia is common in women with ovarian cancer but there are limited prospective data on the frequency and degree of impact on patients. Our objective was to determine the prevalence of insomnia over the first three years after a diagnosis of ovarian cancer; and the relationship between insomnia and quality...

journal_title：Gynecologic oncology

authors： Ross TL,DeFazio A,Friedlander M,Grant P,Nagle CM,Williams M,Webb PM,Beesley VL,OPAL Study Group.

更新日期：2020-09-01 00:00:00

abstract：:Practice changing standardization of lower extremity lymphedema quantitative measurements with integrated patient reported outcomes will likely refine and redefine the optimal risk-reduction strategies to diminish the devastating limb-related dysfunction and morbidity associated with treatment of gynecologic cancers. ...

journal_title：Gynecologic oncology

authors： Russo S,Walker JL,Carlson JW,Carter J,Ward LC,Covens A,Tanner EJ 3rd,Armer JM,Ridner S,Hayes S,Taghian AG,Brunelle C,Lopez-Acevedo M,Davidson BA,Schaverien MV,Ghamande SA,Bernas M,Cheville AL,Yost KJ,Schmitz K,Coy

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:We conducted a case-control study to analyze risk factors for ovarian cancer. METHODS:Cases included 440 women (age range 13-80 years, median 54) with a histologically confirmed diagnosis of epithelial ovarian cancer who were admitted to the Gynecological Oncological Department of Gynecologic Oncology at the...

journal_title：Gynecologic oncology

authors： Greggi S,Parazzini F,Paratore MP,Chatenoud L,Legge F,Mancuso S,La Vecchia C

更新日期：2000-10-01 00:00:00

abstract：:In 74 patients with advanced ovarian cancer, the value of DNA flow cytometry and morphometry was evaluated and compared with histological grading and clinical outcome. By means of both DNA flow cytometry and morphometry a clear distinction was found between a favorable group of 15 patients, with a median survival of m...

journal_title：Gynecologic oncology

authors： Rodenburg CJ,Cornelisse CJ,Hermans J,Fleuren GJ

更新日期：1988-02-01 00:00:00

abstract：OBJECTIVES:Chemotherapy is the preferred therapeutic approach for the therapy of advanced ovarian cancer, but a successful long-term treatment is prevented by the development of drug resistance. Recent works have underlined the involvement of non-coding RNAs, microRNAs (miRNAs) in cancer development, with several conje...

journal_title：Gynecologic oncology

authors： Sorrentino A,Liu CG,Addario A,Peschle C,Scambia G,Ferlini C

更新日期：2008-12-01 00:00:00