Abstract:
BACKGROUND:Herpes gestationis (HG) is a rare, recurrent, pruritic, vesicobullous dermatosis occurring predominantly in pregnancy and seldom in early puerperium. Reports of the association of HG with choriocarcinoma are extremely rare and this case highlights such a possible link. CASE:This case focuses on the late postpartal manifestation of HG being associated with metastatic high-risk choriocarcinoma. Direct immunofluorescence was used to verify the diagnosis of HG. Symptomatic therapy with corticosteroids and antihistamines alleviated the pruritic symptoms associated with HG, but only the recurrent course of chemotherapy for the choriocarcinoma resulted in complete disappearance of all signs and symptoms of the HG. CONCLUSION:The time course of this case highlights once again the possible association of HG as a paraneoplastic syndrome of choriocarcinoma.
journal_name
Gynecol Oncoljournal_title
Gynecologic oncologyauthors
Djahansouzi S,Nestle-Kraemling C,Dall P,Bender HG,Hanstein Bdoi
10.1016/s0090-8258(03)00070-2subject
Has Abstractpub_date
2003-05-01 00:00:00pages
334-7issue
2eissn
0090-8258issn
1095-6859pii
S0090825803000702journal_volume
89pub_type
杂志文章abstract:OBJECTIVE:Most women with ovarian cancer relapse and undergo further chemotherapy however evidence regarding the benefits of this for women with platinum-resistant disease is limited. Our objective was to determine whether there was a quality of life improvement or treatment response among women treated for platinum-re...
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