The cost-effectiveness of selective lymphadenectomy based on a preoperative prediction model in patients with endometrial cancer: insights from the US and Korean healthcare systems.

abstract：:Significant vaginal discharge of clear fluid after Wertheim-Taussig hysterectomy with bilateral salpingo-oophorectomy is most often due to urinary fistula. Rarely, the same symptom may be caused by lymphatic fistula, which has not been reported previously. The differentiation between lymph and urine is simple. If this...

journal_title：Gynecologic oncology

authors： Lau TK,Wong WS

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:To compare the oncologic outcomes of women who underwent a fertility-sparing radical trachelectomy (RT) to those who underwent a radical hysterectomy (RH) for stage IB1 cervical carcinoma. METHODS:We performed a case-control study of all patients with stage IB1 cervical carcinoma who underwent a vaginal or a...

journal_title：Gynecologic oncology

authors： Diaz JP,Sonoda Y,Leitao MM,Zivanovic O,Brown CL,Chi DS,Barakat RR,Abu-Rustum NR

更新日期：2008-11-01 00:00:00

abstract：:From 1971 through 1981, 81 women received 4350 to 5075 rad to the periaortic lymph nodes as part of their primary management for carcinoma of the uterine cervix. While two patients developed chronic small bowel damage, only one required surgical intervention. Five-year disease-free survival was 40%. Approximately one-...

journal_title：Gynecologic oncology

authors： Potish R,Adcock L,Jones T Jr,Levitt S,Prem K,Savage J,Twiggs L

更新日期：1983-02-01 00:00:00

abstract：PURPOSE:A constituent of green tea, (-)-epigallocatechin-3-gallate (EGCG), has been known to possess anti-cancer properties. In this study, we investigated the time-course anticancer effects of EGCG on human ovarian cancer cells to provide insights into the molecular-level understanding of growth suppression mechanism ...

journal_title：Gynecologic oncology

authors： Huh SW,Bae SM,Kim YW,Lee JM,Namkoong SE,Lee IP,Kim SH,Kim CK,Ahn WS

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVE:Given the paucity of data regarding the patterns of metastasis from ovarian sex cord-stromal tumors (SCSTs), we sought to determine the risk of lymph node metastasis in patients with SCSTs. METHODS:A retrospective chart review was performed after clinical and pathology databases were queried for ovarian SCST...

journal_title：Gynecologic oncology

authors： Brown J,Sood AK,Deavers MT,Milojevic L,Gershenson DM

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:Our aim was to characterize the pathological, molecular and clinical outcomes of clear cell carcinoma of the endometrium (CCC). METHODS:CCC underwent ProMisE (Proactive Molecular Risk Classifier for Endometrial Cancer) classification identifying four molecular subtypes: i) 'POLEmut' for ECs with pathogenic P...

journal_title：Gynecologic oncology

authors： Kim SR,Cloutier BT,Leung S,Cochrane D,Britton H,Pina A,Storness-Bliss C,Farnell D,Huang L,Shum K,Lum A,Senz J,Lee CH,Gilks CB,Hoang L,McAlpine JN

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Diagnosis and treatment for a life threatening illness such as cancer are known to be psychologically impactful. However, little is known about the influence that non-cancer life stressors have on the quality of life (QOL) of ovarian cancer patients. The goal of the present study was to examine associations ...

journal_title：Gynecologic oncology

authors： Lutgendorf SK,Slavich GM,Degeest K,Goodheart M,Bender D,Thaker PH,Penedo F,Zimmerman B,Lucci J 3rd,Mendez L,Collins K,Sood AK

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To examine the DNA methyltransferase (DNMT) mRNA and protein levels in endometrioid and serous cancers and to study the relationship between DNA methyltransferase expression and endometrial cancer development. METHODS:Normal endometrium, Grade I and Grade III endometrioid carcinoma tissues and cell lines, as...

journal_title：Gynecologic oncology

authors： Xiong Y,Dowdy SC,Xue A,Shujuan J,Eberhardt NL,Podratz KC,Jiang SW

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:Nuclear lamina plays important roles in nuclear shape and mechanical stability. Many studies demonstrated that defects of lamin-A were associated with several diseases, but little research was found on its potential roles in ovarian cancer. METHODS:GEPIA and GEO database were used to analyze lamin-A in ovari...

journal_title：Gynecologic oncology

authors： Wang Y,Jiang J,He L,Gong G,Wu X

更新日期：2019-01-01 00:00:00

abstract：:Clear-cell hidradenocarcinoma is a malignant tumor of sweat gland origin. It is most often found on the trunk, head, and extremities. This case report describes a rare occurrence of this tumor on the vulva of a young woman. The discovery of metastatic disease reflects the potentially aggressive nature of this tumor. ...

journal_title：Gynecologic oncology

authors： Messing MJ,Richardson MS,Smith MT,King L,Gallup DG

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVES:Chemotherapy is the preferred therapeutic approach for the therapy of advanced ovarian cancer, but a successful long-term treatment is prevented by the development of drug resistance. Recent works have underlined the involvement of non-coding RNAs, microRNAs (miRNAs) in cancer development, with several conje...

journal_title：Gynecologic oncology

authors： Sorrentino A,Liu CG,Addario A,Peschle C,Scambia G,Ferlini C

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to examine the clinicopathologic correlates of T-regulatory (T(reg)) cell infiltration in serous ovarian cancers and to define gene signatures associated with high T(reg)s. METHODS:Tumor infiltrating T(reg) and cytotoxic T-cells (CTLs) were quantitated in 232 primary serous ov...

journal_title：Gynecologic oncology

authors： Barnett JC,Bean SM,Whitaker RS,Kondoh E,Baba T,Fujii S,Marks JR,Dressman HK,Murphy SK,Berchuck A

更新日期：2010-03-01 00:00:00

abstract：:The role of adjuvant chemotherapy in surgically staged stage I clear cell ovarian cancer (OCCC) is unclear. Here, we performed a systematic review and meta-analysis in order to evaluate the role of chemotherapy vs. observation in stage I OCCC. This systematic review was registered in the International Prospective Regi...

journal_title：Gynecologic oncology

authors： Bogani G,Ditto A,Lopez S,Bertolina F,Murgia F,Pinelli C,Chiappa V,Raspagliesi F

更新日期：2020-04-01 00:00:00

abstract：:We present the largest multicenter study evaluating whether intraoperative visual estimation can accurately assess the depth of myometrial invasion in patients with endometrial cancer. The study population consisted of 403 consecutive women who underwent total hysterectomy for endometrial cancer. After the uterus was ...

journal_title：Gynecologic oncology

authors： Franchi M,Ghezzi F,Melpignano M,Cherchi PL,Scarabelli C,Apolloni C,Zanaboni F

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to evaluate the histological outcome of laser ring biopsies in patients with one or more smears showing cytological mild dyskaryosis where punch biopsies were not performed. The possibilities of predicting histological findings of CIN 2 and CIN 3 were analyzed. METHODS:The study com...

journal_title：Gynecologic oncology

authors： Risberg B,Andersson A,Lie KA,Nordin B,Zetterberg C

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVE:The first-line chemotherapy for ovarian cancer is based on a combination of platinum and taxane. To date, no reliable predictive biomarker has been recognized that is capable of identifying patients with pre-existing resistance to these agents. Here, we have established an integrated database and identified t...

journal_title：Gynecologic oncology

authors： Fekete JT,Ősz Á,Pete I,Nagy GR,Vereczkey I,Győrffy B

更新日期：2020-03-01 00:00:00

abstract：:A study was undertaken to determine the potential value of involucrin immunostaining, a protein synthesized by mature squamous epithelial cells, in distinguishing benign from neoplastic lesions in cervical pathology. A total of 146 cervical biopsies were analyzed using an indirect immunoperoxidase method and polyclona...

journal_title：Gynecologic oncology

authors： Serra V,Ramirez AA,Lara C,Marzo C,Castells A,Bonilla-Musoles F

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine whether there is a link between integrins and components of the plasminogen system, regarding tumor cell invasion to the artificial extracellular matrix. METHODS:Immunocytochemistry was performed with antibodies directed against integrins alpha2beta1, alpha4beta1,...

journal_title：Gynecologic oncology

authors： Prifti S,Zourab Y,Koumouridis A,Bohlmann M,Strowitzki T,Rabe T

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the 5-year survival probability (SP) of patients treated for ovarian clear cell adenocarcinoma (OCCA) at a single tertiary institution and to compare it to the 5-year SP of patients with other histologic subtypes of epithelial ovarian cancer. METHODS:Sixty-four patients ...

journal_title：Gynecologic oncology

authors： Kennedy AW,Markman M,Biscotti CV,Emery JD,Rybicki LA

更新日期：1999-07-01 00:00:00

abstract：PURPOSE:Efflux transporters of the ATP-binding cassette (ABC) family are major determinants of chemoresistance in tumor cells. This study examined associations between functional variants in ABCB1, ABCC2 and ABCG2 genes and clinical outcomes in patients with epithelial ovarian/primary peritoneal cancer (EOC/PPC) follow...

journal_title：Gynecologic oncology

authors： Tian C,Ambrosone CB,Darcy KM,Krivak TC,Armstrong DK,Bookman MA,Davis W,Zhao H,Moysich K,Gallion H,DeLoia JA

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Sertoli-Leydig cell tumors (SLCT) constitute only 0.5% of all primary ovarian neoplasms. We report a unique diagnostic method (selective laparoscopic venous sampling) and a rare case of a contralateral second primary tumor. CASE:A 14-year-old female presented with hyperandrogenic complaints and an increased...

journal_title：Gynecologic oncology

authors： White LC,Buchanan KD,O'Leary TD,Carlan SJ,Boothby R

更新日期：2003-10-01 00:00:00

abstract：:The objective of this study was to evaluate the prognostic value of a convenient nuclear grading system based on only the proportion of nuclei measuring more than 10 microm in length at the shortest axis in endometrial carcinomas. Of the 235 cases reviewed, 9 serous and 5 clear cell adenocarcinomas and 2 small cell ca...

journal_title：Gynecologic oncology

authors： Hachisuga T,Kawarabayashi T,Iwasaka T,Sugimori H,Kamura T,Tsuneyoshi M

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Psammocarcinomas are rare epithelial tumors usually originating from the ovarian surface epithelium or the peritoneum. In our case, a peritoneal psammocarcinoma was incidental surgical finding during laparotomy. CASE:An 83-year-old woman underwent surgery for bowel obstruction. Intraoperativelly, a bowel ca...

journal_title：Gynecologic oncology

authors： Koumoundourou D,Michail G,Kourounis G,Ravazoula P

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVE:A 10-point "Surgical Apgar Score" (SAS) for predicting postoperative complications after general and vascular operations has recently been developed and validated. We sought to estimate the ability of this metric to predict major postoperative complications in women undergoing ovarian cancer cytoreductive pro...

journal_title：Gynecologic oncology

authors： Zighelboim I,Kizer N,Taylor NP,Case AS,Gao F,Thaker PH,Rader JS,Massad LS,Mutch DG,Powell MA

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:This study aimed to determine if there is a causal relationship between removal of the circumflex iliac nodes distal to the external iliac nodes (CINDEIN) and postoperative lower-extremity lymphedema (POLEL) after systematic lymphadenectomy in patients with cervical cancer. METHODS:A retrospective chart revi...

journal_title：Gynecologic oncology

authors： Yamazaki H,Todo Y,Takeshita S,Ohba Y,Sudo S,Minobe S,Okamoto K,Yamashiro K,Kato H

更新日期：2015-11-01 00:00:00

abstract：:A new cell line, CUMC-3, has been derived from an invasive nonkeratinizing squamous cell carcinoma of the uterine cervix in a 32-year-old patient. It has been maintained in long-term culture for 59 months, and passaged over 310 times. Monolayer-cultured cells were polygonal in shape, showing a pavement-like arrangemen...

journal_title：Gynecologic oncology

authors： Kim JW,Cho YH,Lyu MS,Lee CG,Jung JK,Kim SJ,Namkoong SE

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:In the present study we detected 72-kDa metalloproteinase expression in our series of early stage cervical carcinomas and analyzed the relationship between 72-kDa metalloproteinase staining and risk of nodal involvement with the goal of identifying a parameter useful in predicting the metastatic potential of ...

journal_title：Gynecologic oncology

authors： Garzetti GG,Ciavattini A,Lucarini G,Goteri G,Romanini C,Biagini G

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:Pegylated liposomal doxorubicin (PLD) has similar reported clinical efficacy compared with conventional doxorubicin with less cardiotoxicity. The manufacturer of PLD advises that cardiac function should be evaluated with endomyocardial biopsy, echocardiography or multigated radionucleotide scan (MUGA) pre-tre...

journal_title：Gynecologic oncology

authors： Dioun SM,Vilardo N,Goldberg GL,Gressel GM

更新日期：2019-11-01 00:00:00

abstract：:Absorbable synthetic mesh (910-polyglactin) was used to create an intestinal sling in six patients undergoing surgical staging of pelvic malignancies prior to radiation therapy. All patients had effective compartmentalization of small intestine out of the pelvis which persisted throughout the duration of radiation the...

journal_title：Gynecologic oncology

authors： Soper JT,Clarke-Pearson DL,Creasman WT

更新日期：1988-03-01 00:00:00

abstract：:Clear cell carcinoma of the ovary accounts for 2 to 3% of all epithelial ovarian neoplasms. Patient profiles, pathological characteristics, and results of treatment are reviewed for 59 patients. The median age was 51. Disease extent at diagnosis was as follows: stage I, 18 patients (31%); stage II, 20 patients (34%); ...

journal_title：Gynecologic oncology

authors： Crozier MA,Copeland LJ,Silva EG,Gershenson DM,Stringer CA

更新日期：1989-11-01 00:00:00