Course of chemotherapy-induced peripheral neuropathy and its impact on health-related quality of life among ovarian cancer patients: A longitudinal study.

abstract：:Between August 1990 and January 1992, 184 patients with squamous cell carcinoma of the cervix, FIGO stage IIB-IVA, were randomized to receive either two cycles of bleomycin, ifosfamide-mesna, and cis-platinum (BIP) chemotherapy (CT) followed by radiotherapy (RT) ("CT-RT group," n = 94) or RT alone (RT group, n = 90). ...

journal_title：Gynecologic oncology

authors： Kumar L,Kaushal R,Nandy M,Biswal BM,Kumar S,Kriplani A,Singh R,Rath GK,Kochupillai V

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:The AGO-OVAR16 study was designed to test the efficacy, safety, and tolerability of pazopanib maintenance after first-line chemotherapy in patients with newly diagnosed advanced ovarian cancer (AOC). METHODS:Nine hundred and forty patients with histologically confirmed AOC, International Federation of Gyneco...

journal_title：Gynecologic oncology

authors： Vergote I,du Bois A,Floquet A,Rau J,Kim JW,Del Campo JM,Friedlander M,Pignata S,Fujiwara K,Colombo N,Mirza MR,Monk BJ,Tsibulak I,Calvert PM,Herzog TJ,Hanker LC,Meunier J,Lee JY,Bologna A,Carrasco-Alfonso MJ,Harter

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:The concept of "platinum sensitivity" has been widely applied in the management of recurrent ovarian cancer. This study aimed to evaluate the applicability of this concept to recurrent endometrial cancer. PATIENTS AND METHODS:In this multicenter retrospective cohort study, the clinical data of patients with ...

journal_title：Gynecologic oncology

authors： Nagao S,Nishio S,Michimae H,Tanabe H,Okada S,Otsuki T,Tanioka M,Fujiwara K,Suzuki M,Kigawa J

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To determine the overall survival and relative effect of multiple prognostic variables in cohorts of patients with advanced-stage ovarian cancer treated with platinum-based neoadjuvant chemotherapy in lieu of primary cytoreductive surgery. METHODS:Twenty-two cohorts of patients with Stage III and IV ovarian ...

journal_title：Gynecologic oncology

authors： Bristow RE,Chi DS

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Luteinized thecoma of the ovary associated with sclerosing peritonitis is a rare tumor that has no standard definitive treatment regimen. CASE:A 25 year-old patient diagnosed with luteinized thecoma and sclerosing peritonitis in the omentum. The patient received high dose corticosteroids (IV Hydrocortisone ...

journal_title：Gynecologic oncology

authors： Schonman R,Klein Z,Edelstein E,Czernobilsky B,Fishman A

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:Aberrant expression of HER2/neu and PIK3CA gene products secondary to amplification/mutations are common in high-grade-serous-endometrial (USC) and ovarian-cancers (HGSOC). Because scant information is currently available in the literature on the potential negative effect of PIK3CA mutations on the activity o...

journal_title：Gynecologic oncology

authors： Bonazzoli E,Cocco E,Lopez S,Bellone S,Zammataro L,Bianchi A,Manzano A,Yadav G,Manara P,Perrone E,Haines K,Espinal M,Dugan K,Menderes G,Altwerger G,Han C,Zeybek B,Litkouhi B,Ratner E,Silasi DA,Huang GS,Azodi M,

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:To estimate the likelihood of occult cancer diagnosis at prophylactic oophorectomy in BRCA1 and BRCA2 carriers in different age groups and to determine the histopathology of these lesions. METHODS:We describe a series of 159 female BRCA1 or BRCA2 carriers who underwent prophylactic oophorectomy at the Univer...

journal_title：Gynecologic oncology

authors： Finch A,Shaw P,Rosen B,Murphy J,Narod SA,Colgan TJ

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to analyze our experience with colorectal function preservation at the time of pelvic exenteration. METHODS:Between January 1980 and December 2001, 201 pelvic exenterations for gynecologic malignancies were performed in our hospital. Ninety-eight were supralevator exenteration...

journal_title：Gynecologic oncology

authors： Moutardier V,Houvenaeghel G,Lelong B,Mokart D,Delpero JR

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVES:Routine lymphadenectomy (LA) in early stage endometrial cancer does not improve survival. However, in the absence of lymph node metastasis, radiotherapy (RT) could be withheld and hence could result in less morbidity. Our aim was to evaluate health related quality of life (HRQL) in endometrial cancer survivo...

journal_title：Gynecologic oncology

authors： van de Poll-Franse LV,Pijnenborg JM,Boll D,Vos MC,van den Berg H,Lybeert ML,de Winter K,Kruitwagen RF

更新日期：2012-10-01 00:00:00

abstract：:From November 1983 to October 1992, 22 patients with invasive cervical cancer stage IB through stage IIIB with metastasis to para-aortic nodes were entered in this study. Five patients were excluded. Of 17 remaining evaluable patients, 5 (29%) were stage IB, 6 (35%) were stage IIB, and 6 (35%) were stage IIIB. Four (2...

journal_title：Gynecologic oncology

authors： Husseinzadeh N,Shrake P,DeEulis T,Rowley K,Aron B

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Timely hospice referral is an essential component of quality end-of-life care, although a growing body of research suggests that for patients with various types of cancer, hospice referrals often occur very late in the course of care, and are marked by sociodemographic disparities. However, little is known a...

journal_title：Gynecologic oncology

authors： Fairfield KM,Murray KM,Wierman HR,Han PK,Hallen S,Miesfeldt S,Trimble EL,Warren JL,Earle CC

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:Patients with advanced epithelial ovarian cancer treated with salvage therapy using new combinations of systemic chemotherapy, radiation therapy, and systemic immunotherapy have had limited success. Since the most common site of relapse or failure to conventional systemic chemotherapy has been the peritoneal ...

journal_title：Gynecologic oncology

authors： Feun LG,Blessing JA,Major FJ,DiSaia PJ,Alvarez RD,Berek JS

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVE:The ABC transporter MRP2 (ABCC2) can mediate cisplatin efflux, and over-expression of MRP2 has been associated with cisplatin resistance in cancer cell lines. The aim of this study was to determine the role of MRP2 in modulating cisplatin cytotoxicity in normal cells as well as the relationship between MRP2 e...

journal_title：Gynecologic oncology

authors： Guminski AD,Balleine RL,Chiew YE,Webster LR,Tapner M,Farrell GC,Harnett PR,Defazio A

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:Invasion of the extracellular matrix and blood vessels by malignant neoplasms, with subsequent distant dissemination, is a key event in tumor progression. This process appears to be mediated largely through the action of matrix metalloproteinases (MMPs), a family of proteolytic enzymes produced by both stroma...

journal_title：Gynecologic oncology

authors： Davidson B,Goldberg I,Kopolovic J,Lerner-Geva L,Gotlieb WH,Weis B,Ben-Baruch G,Reich R

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:While ovarian borderline tumors are common, their fallopian tube counterparts are extremely rare. We describe the first case of a serous borderline paratubal tumor with a review of the literature on paratubal and tubal low malignant potential tumors. CASE:A 26 year-old woman presented with acute onset of sh...

journal_title：Gynecologic oncology

authors： Seamon LG,Holt CN,Suarez A,Richardson DL,Carlson MJ,O'Malley DM

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To propose a risk-specific follow-up protocol for endometrial carcinoma patients. METHODS:A retrospective cohort of endometrial carcinoma patients was used to identify risk factors for recurrence. Based on a profile of risk factors, women were classified at either low or high risk for recurrence (median foll...

journal_title：Gynecologic oncology

authors： Shumsky AG,Brasher PM,Stuart GC,Nation JG

更新日期：1997-06-01 00:00:00

abstract：:MicroRNA molecules are small, single-stranded RNA molecules that function to regulate networks of genes. They play important roles in normal female reproductive tract biology, as well as in the pathogenesis and progression of epithelial ovarian cancer. DROSHA, DICER, and Argonaute proteins are components of the microR...

journal_title：Gynecologic oncology

authors： Wang X,Ivan M,Hawkins SM

更新日期：2017-11-01 00:00:00

abstract：:A 58-year-old postmenopausal woman with primary ovarian serous carcinoma presented with the syndrome of inappropriate antidiuresis (SIAD). Preoperative workup showed serum sodium level of 110 mEq/liter and antidiuretic hormone level of 3.3 pg/ml. The serum and urine osmolarity were 239 and 371, respectively. Antidiure...

journal_title：Gynecologic oncology

authors： Taskin M,Barker B,Calanog A,Jormark S

更新日期：1996-09-01 00:00:00

abstract：:Absorbable synthetic mesh (910-polyglactin) was used to create an intestinal sling in six patients undergoing surgical staging of pelvic malignancies prior to radiation therapy. All patients had effective compartmentalization of small intestine out of the pelvis which persisted throughout the duration of radiation the...

journal_title：Gynecologic oncology

authors： Soper JT,Clarke-Pearson DL,Creasman WT

更新日期：1988-03-01 00:00:00

abstract：:The oncogene specific mRNA of c-erbB-2 was detected by the S1 nuclease protection assay in 95 ovarian cancer specimens. In 79 primary carcinomas, we found 16 (20%) with strong expression, 13 (17%) with weak expression, 4 (5%) with very weak expression, and 46 (58%) with no expression. In 3 of 16 recurrencies (19%) a s...

journal_title：Gynecologic oncology

authors： Tanner B,Kreutz E,Weikel W,Meinert R,Oesch F,Knapstein PG,Becker R

更新日期：1996-08-01 00:00:00

abstract：:Studies using serological and culture techniques indicate that chlamydial infection is frequently associated with cervical intraepithelial neoplasia (CIN). This relationship was investigated by examining a series of biopsies containing normal epithelium, non-neoplastic condylomatous epithelium, and neoplastic epitheli...

journal_title：Gynecologic oncology

authors： Mitao M,Reumann W,Winkler B,Richart RM,Fujiwara A,Crum CP

更新日期：1984-09-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between molecular subtype, intraperitoneal (IP) disease dissemination patterns, resectability, and overall survival (OS) in advanced high-grade serous ovarian cancer (HGSOC). METHODS:Patients undergoing primary surgery for stage III-IV HGSOC at Mayo Clinic from 1994 to 2011 we...

journal_title：Gynecologic oncology

authors： Torres D,Wang C,Kumar A,Bakkum-Gamez JN,Weaver AL,McGree ME,Konecny GE,Goode EL,Cliby WA

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:To report the intermediate-term results of trans-abdominal ultrasound (TAUS)-guided brachytherapy in cervical cancer. MATERIALS AND METHODS:Ninety-two patients with cervical cancer (stage IB-IVA, according to FIGO staging), were treated by curative radiotherapy from February 2012 to June 2015. All patients ...

journal_title：Gynecologic oncology

authors： Tharavichitkul E,Chakrabandhu S,Klunklin P,Onchan W,Jia-Mahasap B,Wanwilairat S,Tippanya D,Jayasvasti R,Sripan P,Galalae RM,Chitapanarux I

更新日期：2018-03-01 00:00:00

abstract：:Primary adenocarcinoma of the jejunum which accounts for only approximately 3% of all gastrointestinal tract malignancies, is distinctly unusual. Ovarian metastasis from a jejunal cancer is extremely rare. It has significant therapeutic and prognostic implications to differentiate primary ovarian carcinoma from metast...

journal_title：Gynecologic oncology

authors： Tsuruchi N,Kubota H,Tsukamoto N,Kurano A

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:Estimate the prevalence of cardiovascular disease risk factors and endpoints in women with BRCA mutations. METHODS:Women, age 40 and older, with BRCA mutations identified in Kaiser Permanente Northern California completed a questionnaire and underwent a lipid and fasting glucose panel. Bivariable analysis of...

journal_title：Gynecologic oncology

authors： Powell CB,Alabaster A,Armstrong MA,Stoller N,Raine-Bennett T

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVES:The objectives of this phase II trial were to assess the activity and tolerability of the combination of bevacizumab and erlotinib in patients with recurrent ovarian, primary peritoneal or fallopian tube cancer. METHODS:This was a single arm, multicenter phase II trial with overall objective response as the...

journal_title：Gynecologic oncology

authors： Nimeiri HS,Oza AM,Morgan RJ,Friberg G,Kasza K,Faoro L,Salgia R,Stadler WM,Vokes EE,Fleming GF,Chicago Phase II Consortium.,PMH Phase II Consortium.,California Phase II Consortium.

更新日期：2008-07-01 00:00:00

abstract：:Significant vaginal discharge of clear fluid after Wertheim-Taussig hysterectomy with bilateral salpingo-oophorectomy is most often due to urinary fistula. Rarely, the same symptom may be caused by lymphatic fistula, which has not been reported previously. The differentiation between lymph and urine is simple. If this...

journal_title：Gynecologic oncology

authors： Lau TK,Wong WS

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:To evaluate clinicopathological factors and survival outcome of patients with advanced epithelial ovarian carcinoma undergoing multiple bowel resections to achieve optimal (< or = 1 cm) cytoreduction. METHODS:A case-control study was performed identifying patients undergoing optimal primary cytoreductive sur...

journal_title：Gynecologic oncology

authors： Salani R,Zahurak ML,Santillan A,Giuntoli RL 2nd,Bristow RE

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the hospital and patient factors associated with robotic surgery for endometrial cancer in the United States. METHODS:Data was obtained from the Nationwide Inpatient Sample from the year 2010. Chi-squared and multivariate analyses were used for statistical analysis. RESULTS:Of the 6560 endometri...

journal_title：Gynecologic oncology

authors： Chan JK,Gardner AB,Taylor K,Blansit K,Thompson CA,Brooks R,Yu X,Kapp DS

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVES:Endometrioid adenocarcinoma of the endometrium (EEC) is the most common histologic type of endometrial cancer, with stage being the most critical prognostic factor. Cervical involvement (CI), divided into IIA (epithelial involvement) and IIB (stromal invasion), is overall associated with decreased survival (...

journal_title：Gynecologic oncology

authors： Orezzoli JP,Sioletic S,Olawaiye A,Oliva E,del Carmen MG

更新日期：2009-06-01 00:00:00