Risk-specific follow-up for endometrial carcinoma patients.

Abstract:

OBJECTIVE:To propose a risk-specific follow-up protocol for endometrial carcinoma patients. METHODS:A retrospective cohort of endometrial carcinoma patients was used to identify risk factors for recurrence. Based on a profile of risk factors, women were classified at either low or high risk for recurrence (median follow-up 70 months). The classification system was validated on a subsequent cohort. RESULTS:Surgical stage, grade, and histology were found to be significant predictors (P < 0.001) of recurrence. In the original cohort, patients with stage Ia, grade 1 or 2, or stage Ib, grade 1 adenocarcinoma, had a recurrence rate of 4/98 (4.1%). The remaining high-risk patients had a recurrence rate of 37/158 (23.4%). When applied to the subsequent cohort, the rates were similar: low risk 3/113 (2.7%) and high risk 30/140 (21.4%). Seventy-five percent of recurrences occurred within 3 years of diagnosis and the majority were heralded by site-specific symptoms. CONCLUSIONS:Women with endometrial carcinoma can be successfully classified for low or high risk of recurrence. It is proposed that low-risk patients not be maintained on routine follow-up and that a tailored schedule of follow-up be used for high-risk patients. These changes would serve patients more appropriately and use health care resources more efficiently.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Shumsky AG,Brasher PM,Stuart GC,Nation JG

doi

10.1006/gyno.1997.4698

subject

Has Abstract

pub_date

1997-06-01 00:00:00

pages

379-82

issue

3

eissn

0090-8258

issn

1095-6859

pii

S0090-8258(97)94698-9

journal_volume

65

pub_type

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