Tumor chemoconversion following surgery, chemotherapy, and normalization of serum tumor markers in a woman with a mixed type germ cell ovarian tumor.

abstract：OBJECTIVE:Currently available tumor markers for ovarian cancer are still inadequate in both sensitivity and specificity to be used for population-based screening. Artificial neural network (ANN) as a modeling tool has demonstrated its ability to assimilate information from multiple sources and to detect subtle and comp...

journal_title：Gynecologic oncology

authors： Zhang Z,Yu Y,Xu F,Berchuck A,van Haaften-Day C,Havrilesky LJ,de Bruijn HW,van der Zee AG,Woolas RP,Jacobs IJ,Skates S,Chan DW,Bast RC Jr

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:The purpose of this multicenter, open label, randomized phase III study was to determine whether ixabepilone resulted in improved overall survival (OS) compared with commonly used single-agent chemotherapy (doxorubicin or paclitaxel) in women with locally advanced, recurrent, or metastatic endometrial cancer ...

journal_title：Gynecologic oncology

authors： McMeekin S,Dizon D,Barter J,Scambia G,Manzyuk L,Lisyanskaya A,Oaknin A,Ringuette S,Mukhopadhyay P,Rosenberg J,Vergote I

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Traditionally, hysterectomy is considered definitive therapy for cervical adenocarcinoma in situ (AIS) in women beyond childbearing. CASE:A 45-year-old gravida 2, para 2 patient presented with cervical dysplasia and on pathology review of the large loop excision procedure cervical adenocarcinoma in situ was...

journal_title：Gynecologic oncology

authors： Miller B,Dunn J,Dalrymple J,Krivak TC

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to estimate the clinical response rate and toxicity of daily tamoxifen combined with intermittent weekly medroxyprogesterone acetate (MPA). METHODS:This study reports the results of 61 patients with measurable advanced or recurrent endometrial carcinoma enrolled on this stu...

journal_title：Gynecologic oncology

authors： Whitney CW,Brunetto VL,Zaino RJ,Lentz SS,Sorosky J,Armstrong DK,Lee RB,Gynecologic Oncology Group study.

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:Our goal in this article to describe our initial experience with intensity-modulated whole-pelvis radiation therapy (IM-WPRT) in gynecologic malignancies. METHODS:Between February and August 2000, 15 women with cervical (9) or endometrial (6) cancer received IM-WPRT. All patients received a treatment plannin...

journal_title：Gynecologic oncology

authors： Mundt AJ,Roeske JC,Lujan AE,Yamada SD,Waggoner SE,Fleming G,Rotmensch J

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVES:(1) To determine the response rate of advanced, recurrent, or persistent carcinoma of the cervix to ifosfamide, paclitaxel, and carboplatin chemotherapy; (2) to determine the progression free interval and survival rate in patients treated with this regimen; (3) to describe the toxicities associated with this...

journal_title：Gynecologic oncology

authors： Downs LS Jr,Chura JC,Argenta PA,Judson PL,Ghebre R,Geller MA,Carson LF

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To assess the role of additional biopsies performed with loop electrosurgical excisional procedure (LEEP) in predicting the likelihood of persistent high grade intraepithelial neoplasia. METHODS:Clinicopathologic data were abstracted from women who underwent excision of high grade intraepithelial lesions bet...

journal_title：Gynecologic oncology

authors： Cui Y,Sangi-Haghpeykar H,Patsner B,Bump JMM,Williams-Brown MY,Binder GL,Masand RP,Anderson ML

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To evaluate whether self-report measures of psychological distress and perceived risk were associated with nonadherence to recommended ovarian cancer surveillance. METHODS:Eighty-three patients attending the Familial Ovarian Cancer Clinic (FOCC) at Princess Margaret Hospital were assessed psychosocially prio...

journal_title：Gynecologic oncology

authors： Ritvo P,Irvine J,Robinson G,Brown L,Murphy KJ,Matthew A,Rosen B

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Low-grade endometrial stromal sarcoma is generally an indolent tumor rich in estrogen and progesterone receptors. Objective responses to hormonal therapy, most commonly with megestrol acetate, have been reported. CASE:The patient is a 51-year-old woman who presented with low-grade endometrial stromal sarcom...

journal_title：Gynecologic oncology

authors： Maluf FC,Sabbatini P,Schwartz L,Xia J,Aghajanian C

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to assess efficacy and toxicity of the combination of bleomycin, etoposide, and cisplatin (BEP) in this Phase II trial as first-line therapy for ovarian stromal malignancies. METHODS:Patients with incompletely resected Stages II-IV or recurrent cancer underwent surgical deb...

journal_title：Gynecologic oncology

authors： Homesley HD,Bundy BN,Hurteau JA,Roth LM

更新日期：1999-02-01 00:00:00

abstract：:Young women diagnosed with breast cancer typically face systemic treatments that may delay childbearing or permanently impair their fertility. These concerns add to the stress experienced by young cancer survivors. Timely counseling and providing fertility preservation through cryopreservation of eggs or embryos have ...

journal_title：Gynecologic oncology

authors： Westphal LM,Wapnir IL

更新日期：2012-03-01 00:00:00

abstract：:Malignant pleural effusion is the most common site of stage IV ovarian cancer. A positive cytology is required for a stage IVA diagnosis. Unfortunately, the accuracy rate of pleural cytology remains low. A number of factors have been identified as prognostic for clinical outcomes in patients with epithelial ovarian ca...

journal_title：Gynecologic oncology

authors： Escayola C,Ferron G,Romeo M,Torrent JJ,Querleu D

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine the cost-effectiveness of selective lymphadenectomy using a preoperative prediction model compared to routine lymphadenectomy for patients undergoing surgery for endometrial cancer in the US and Korea. METHODS:We used a modified Markov model to estimate clinical and eco...

journal_title：Gynecologic oncology

authors： Lee JY,Cohn DE,Kim Y,Lee TJ,Barnett JC,Kim JW,Jeon YW,Kim K,Park SM,Kang S

更新日期：2014-12-01 00:00:00

abstract：:Between 1971 and 1979, seventy-four patients with metastatic or advanced recurrent sarcoma of uterine origin were treated with combination chemotherapy consisting of vincristine, actinomycin D, and cyclophosphamide (Cytoxan). The probability of survival at 2 and 5 years was 23 and 15%, respectively. The response rate ...

journal_title：Gynecologic oncology

authors： Hannigan EV,Freedman RS,Elder KW,Rutledge FN

更新日期：1983-04-01 00:00:00

abstract：:In a prospective study, the serum levels of CA 125 were estimated at regular intervals in 139 patients with ovarian carcinoma. Seventy-two of 78 patients with a second-look laparotomy had elevated CA 125 levels initially. The main aim of our investigation was the correlation of CA 125 levels with the histological find...

journal_title：Gynecologic oncology

authors： Meier W,Stieber P,Eiermann W,Schneider A,Fateh-Moghadam A,Hepp H

更新日期：1989-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate directly the utility of Fourier transform infrared microscopy (FTIR-MC) in detecting cervical precancer by comparison with the pathological examination of biopsy tissue. METHODS:Cervical biopsy specimens were obtained from the outpatient department at Kaohsiung Municipal...

journal_title：Gynecologic oncology

authors： Chang JI,Huang YB,Wu PC,Chen CC,Huang SC,Tsai YH

更新日期：2003-12-01 00:00:00

abstract：:Of 369 patients with apparent advanced ovarian cancer entered on a randomized trial between September 1979 and June 1983, 56 survived more than 5 years. Central pathology review confirmed the diagnosis in 318 cases (15 cases not ovarian primary, 36 slides did not reach central review). Two hundred ninety-eight were in...

journal_title：Gynecologic oncology

authors： Tattersall MH,Swanson CE,Solomon HJ

更新日期：1992-12-01 00:00:00

abstract：:The records of 123 patients with Stage I cervical cancer who underwent radical hysterectomy with pelvic lymphadenectomy and para-aortic node sampling from 1981 to 1988 were reviewed to assess the risks of surgery associated with increasing weight and age. Fifty-four patients were obese (20% or more over ideal body wei...

journal_title：Gynecologic oncology

authors： Levrant SG,Fruchter RG,Maiman M

更新日期：1992-06-01 00:00:00

abstract：:Immunohistochemical studies were performed to investigate the prognostic significance of p53 protein expression in 46 patients with stage IIIB squamous cell carcinoma of the uterine cervix who were treated with radiation therapy alone. Tumor cells showed p53 protein expression in 29 of 46 patients. The 5-year overall ...

journal_title：Gynecologic oncology

authors： Ebara T,Mitsuhashi N,Saito Y,Sakurai H,Hasegawa M,Takahashi M,Takahashi T,Hayakawa K,Niibe H

更新日期：1996-11-01 00:00:00

abstract：OBJECTIVE:Persistent infection with oncogenic human papillomavirus (HPV) is known to be the necessary cause of cervical cancer and a majority of vulvar cancers. Persistent HPV infections must evade host immune responses, including cytokines released by activated T-helper (Th) cells. In this study, we investigated the r...

journal_title：Gynecologic oncology

authors： Hardikar S,Johnson LG,Malkki M,Petersdorf EW,Galloway DA,Schwartz SM,Madeleine MM

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE/BACKGROUND:Laparoscopic splenectomy is a potential surgical option for the treatment of isolated gynecologic cancer recurrence to the spleen [1-7]. The purpose of this video is to demonstrate a step-by-step approach for laparoscopic splenectomy in the setting of recurrent, oligometastatic ovarian cancer. MET...

journal_title：Gynecologic oncology

authors： Acosta-Torres S,Fader AN

更新日期：2020-03-01 00:00:00

abstract：:This study evaluated the effects of cisplatin on 18 nerve conduction parameters of median, ulnar, peroneal, and sural nerves in relation to age, magnesium nadir, average magnesium, and magnesium replacement in gynecologic oncology patients. The 37 patients in this study received cisplatin (70 mg/m2) at 4-week interval...

journal_title：Gynecologic oncology

authors： Ashraf M,Riggs JE,Wearden S,Scotchel P

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Metformin has been associated with reduced cancer risk. The mechanisms underlying this cancer protective effect remain unknown. METHODS:"Window of opportunity" study of metformin in women with operable endometrial cancer (EC). Eleven newly diagnosed, untreated, non-diabetic patients with EC received metform...

journal_title：Gynecologic oncology

authors： Laskov I,Drudi L,Beauchamp MC,Yasmeen A,Ferenczy A,Pollak M,Gotlieb WH

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:Racial genetic admixture (RGA), a measure to account for ancestral genetic background that correlates with individual's racial classification, could provide insights on causation of racial disparity in endometrial cancer (EC). Our objective is to evaluate the association of RGA with EC outcomes. METHODS:EC pat...

journal_title：Gynecologic oncology

authors： Rocconi RP,Lankes HA,Brady WE,Goodfellow PJ,Ramirez NC,Alvarez RD,Creasman W,Fernández JR

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this work was to evaluate the ability of testing for high-risk human papillomavirus (HPV) types using the hybrid capture technique to predict the presence of cervical intraepithelial neoplasia (CIN) II,III in patients with repeated atypical squamous cells of undetermined significance (ASCUS) an...

journal_title：Gynecologic oncology

authors： Fait G,Kupferminc MJ,Daniel Y,Geva E,Ron IG,Lessing JB,Bar-Am A

更新日期：2000-11-01 00:00:00

abstract：:Experience with the P.A.S.-PORT, a peripherally implanted central venous access device, is evaluated in a retrospective review of 154 patients from July 1991 to June 1994. Blood could not be aspirated from six patients. Complications included temporary minor thrombophlebitis in seven patients (4.5%), symptomatic axill...

journal_title：Gynecologic oncology

authors： Deppe G,Kahn ML,Malviya VK,Malone JM Jr,Christensen CW

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVE:We wanted to identify genes up-regulated in ovarian tumors that might serve as early markers for ovarian cancer. One promising focus is the family of genes that encode secreted proteases, which play essential roles in tumor invasion and metastasis. Kallikrein 10 (KLK10) is a member of the kallikrein family of...

journal_title：Gynecologic oncology

authors： Shvartsman HS,Lu KH,Lee J,Lillie J,Deavers MT,Clifford S,Wolf JK,Mills GB,Bast RC Jr,Gershenson DM,Schmandt R

更新日期：2003-07-01 00:00:00

abstract：PURPOSE:There is controversy regarding the pattern of lymphatic spread in unilateral stage I invasive ovarian carcinomas. The purpose of this study is to describe the incidence and distribution of lymph node (LN) metastases in ovarian carcinomas clinically confined to one ovary. METHODS:Ninety-six patients with diseas...

journal_title：Gynecologic oncology

authors： Cass I,Li AJ,Runowicz CD,Fields AL,Goldberg GL,Leuchter RS,Lagasse LD,Karlan BY

更新日期：2001-01-01 00:00:00

abstract：:Approximately 20,000 women are diagnosed with ovarian cancer in the United States each year, and some 12,000 women die because of it. Epithelial ovarian cancer, the most common histopathologic type, is uncommon before age 40 years, after which incidence rates increase steeply until age 70-79 years and then decrease so...

journal_title：Gynecologic oncology

authors： Whittemore AS

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:To compare the efficacy of chemotherapy (C) combined with bevacizumab (Bev) versus Bev alone in recurrent, heavily pretreated epithelial ovarian cancer (EOC). METHODS:A multicenter analysis of patients treated from 2004 to 2011 was performed. Demographic, treatment, response, and adverse event information w...

journal_title：Gynecologic oncology

authors： Fuh KC,Secord AA,Bevis KS,Huh W,ElNaggar A,Blansit K,Previs R,Tillmanns T,Kapp DS,Chan JK

更新日期：2015-12-01 00:00:00