Serum levels of CA 125 and histological findings at second-look laparotomy in ovarian carcinoma.

abstract：:The CA 125 radioimmunoassay has been increasingly used to monitor the course of patients with ovarian epithelial carcinomas. The purpose of this report is to describe our experience in the use of this assay and to better define its clinical utility. Fifty-one patients had serum CA 125 follow-up during primary chemothe...

journal_title：Gynecologic oncology

authors： Podczaski E,Whitney C,Manetta A,Larson JE,Kirk J,Stevens CW,Lyter J,Mortel R

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Glucocorticoid receptor (GR) has emerged as an important steroid nuclear receptor in hormone dependent cancers, however few data are available regarding a potential role of GR in endometrial cancer. The aim of this study was to investigate expression of GR in primary and metastatic endometrial cancer lesions...

journal_title：Gynecologic oncology

authors： Tangen IL,Veneris JT,Halle MK,Werner HM,Trovik J,Akslen LA,Salvesen HB,Conzen SD,Fleming GF,Krakstad C

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:53BP1, a critical mediator of the DNA damage response, functions by regulating the balance between homologous recombination (HR) and the more error-prone non-homologous endjoining (NHEJ). Deletion of 53BP1 in brca1 (but not brca2) null cells partially restores HR and reverses sensitivity to poly-ADP-ribose p...

journal_title：Gynecologic oncology

authors： Pennington KP,Wickramanayake A,Norquist BM,Pennil CC,Garcia RL,Agnew KJ,Taniguchi T,Welcsh P,Swisher EM

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Post-irradiation breast sarcoma is a rare and highly aggressive tumor, associated with poor prognosis. However, the mean latent periods reported for postradiation sarcomas after treatment of breast cancer ranges from 5 to 10 years. CASE:We present a rare case of fibrosarcoma of the axilla, diagnosed 23 mont...

journal_title：Gynecologic oncology

authors： Plotti F,Di Donato V,Zullo MA,Angioli R,Panici PB

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To examine the effect of postsurgical surveillance on survival of patients with FIGO stage I/II endometrial adenocarcinoma. METHODS:We examined the records of 354 patients who underwent primary surgical therapy for FIGO stage I/II endometrial adenocarcinoma. In patients who developed recurrent disease, we de...

journal_title：Gynecologic oncology

authors： Berchuck A,Anspach C,Evans AC,Soper JT,Rodriguez GC,Dodge R,Robboy S,Clarke-Pearson DL

更新日期：1995-10-01 00:00:00

abstract：:The carcinoembryonic antigen (CEA) in the cyst fluid of ovarian mucinous and serous tumors was investigated. The molecular weight and antigenicity of the CEA from both ovarian tumors were very similar to those of colon cancer CEA as determined by SDS electrophoresis and double immunodiffusion on agar plates. In the cy...

journal_title：Gynecologic oncology

authors： Tohya T,Iwamasa T,Maeyama M

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVES:While there are many psychosocial interventions for cancer patients, few are brief in nature. The aim of this study was to investigate the usefulness of a single-visit psychosocial intervention for gynecologic cancer patients. METHODS:One hundred women attending a gynecologic cancer clinic as new patients w...

journal_title：Gynecologic oncology

authors： Powell CB,Kneier A,Chen LM,Rubin M,Kronewetter C,Levine E

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:A phase II study was conducted to determine the efficacy of oxaliplatin therapy in patients with previously treated squamous cell carcinoma of the cervix. METHODS:Eligible patients were to have measurable disease and not more than one prior chemotherapy regimen that could include carboplatin or cisplatin but...

journal_title：Gynecologic oncology

authors： Fracasso PM,Blessing JA,Wolf J,Rocereto TF,Berek JS,Waggoner S

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:Chemotherapy-induced peripheral neuropathy (CIPN) presents itself as sensory peripheral neuropathy (SPN) or motor peripheral neuropathy (MPN). Our aim was to examine the course of SPN and MPN, and their impact on health-related quality of life (HRQoL) among ovarian cancer patients. METHODS:All newly diagnose...

journal_title：Gynecologic oncology

authors： Bonhof CS,Mols F,Vos MC,Pijnenborg JMA,Boll D,Vreugdenhil G,Ezendam NPM,van de Poll-Franse LV

更新日期：2018-06-01 00:00:00

abstract：:Adenocarcinoma of the cervix represents an increasing percentage of cervical cancers as well as a controversial clinical problem. One hundred seventy-two cases of adenocarcinoma were treated at The University of Michigan Medical Center from 1970 to 1984, representing 16.8% of cervical cancers. Of this group 84 patient...

journal_title：Gynecologic oncology

authors： Hopkins MP,Sutton P,Roberts JA

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Improvements in surgical technique of pelvic exenteration have mainly occurred in the reconstructive phase of the procedure. Quality of life seems to be improved when performing continent rather than non-continent urinary diversion [1]. Unfortunately, Miami continent urinary pouch is a surgical technique not...

journal_title：Gynecologic oncology

authors： Angeles MA,Martínez-Gómez C,Martinez A,Ferron G

更新日期：2018-08-01 00:00:00

abstract：:To determine the morbidity associated with delivery of intraperitoneal chemotherapy via subcutaneous semipermanent infusion catheters, we analyzed the data on 227 patients treated from April 1985 through December 1989. A total of 249 catheters were inserted and used to administer chemotherapy in these patients. There ...

journal_title：Gynecologic oncology

authors： Davidson SA,Rubin SC,Markman M,Jones WB,Hakes TB,Reichman B,Almadrones L,Chapman D,Lewis JL Jr,Hoskins WJ

更新日期：1991-05-01 00:00:00

abstract：:Forty-two patients with malignant, mixed mesodermal tumors of the uterus were identified by retrospective chart review. Only 2 patients were premenopausal at the time of diagnosis. Six of the patients had previously received pelvic radiotherapy. Surgical/pathologic findings were inconsistent with clinical staging in 1...

journal_title：Gynecologic oncology

authors： Podczaski ES,Woomert CA,Stevens CW Jr,Manetta A,Larson JE,Zaino RJ,Mortel R

更新日期：1989-02-01 00:00:00

abstract：OBJECTIVE:Data has suggested obesity as an independent prognostic factor for lower survival in patients with epithelial ovarian cancer (EOC). We sought to determine if obesity portends a disadvantage to surgical outcomes at the time of initial surgery affecting survival. METHODS:A retrospective chart review of patient...

journal_title：Gynecologic oncology

authors： Matthews KS,Straughn JM Jr,Kemper MK,Hoskins KE,Wang W,Rocconi RP

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Evidence on the incidence and risk factors for lower limb lymphedema (LLL) associated with endometrial cancer is limited. Our objective was to use data from a prospective, longitudinal gynecological cancer cohort study to determine LLL incidence up to 24 months post-diagnosis of endometrial cancer and to exp...

journal_title：Gynecologic oncology

authors： Pigott A,Obermair A,Janda M,Vagenas D,Ward LC,Reul-Hirche H,Hayes SC

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVES:This trial was conducted to evaluate the safety and efficacy of cisplatin plus gemcitabine in previously treated squamous cell carcinoma of the cervix. SUBJECTS AND METHODS:All women had measurable histologically confirmed squamous cell cervical cancer and a GOG performance status less than or equal to 2. T...

journal_title：Gynecologic oncology

authors： Brewer CA,Blessing JA,Nagourney RA,McMeekin DS,Lele S,Zweizig SL

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:Epithelial ovarian cancer (EOC) spreads intra-abdominally and to the retroperitoneal lymph nodes. A greater number of distant metastases are revealed by (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) compared to conventional imaging methods. We aimed to investigate th...

journal_title：Gynecologic oncology

authors： Hynninen J,Auranen A,Carpén O,Dean K,Seppänen M,Kemppainen J,Lavonius M,Lisinen I,Virtanen J,Grénman S

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Herpes gestationis (HG) is a rare, recurrent, pruritic, vesicobullous dermatosis occurring predominantly in pregnancy and seldom in early puerperium. Reports of the association of HG with choriocarcinoma are extremely rare and this case highlights such a possible link. CASE:This case focuses on the late pos...

journal_title：Gynecologic oncology

authors： Djahansouzi S,Nestle-Kraemling C,Dall P,Bender HG,Hanstein B

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess the long-term effect of gonadotropin-releasing hormone analogues (GnRH-a) in combination with high-dose progestogens in the treatment of atypical endometrial hyperplasia in selected surgical high-risk patients and in women desiring reproductive potential. We hypothesized th...

journal_title：Gynecologic oncology

authors： Pérez-Medina T,Bajo J,Folgueira G,Haya J,Ortega P

更新日期：1999-05-01 00:00:00

abstract：:A comprehensive understanding of retroperitoneal lymphatic involvement is lacking in tumors of low malignant potential. This study was undertaken to evaluate retroperitoneal lymphatic involvement in patients with ovarian tumors of low malignant potential. One hundred seventy-one patients were diagnosed with epithelial...

journal_title：Gynecologic oncology

authors： Leake JF,Rader JS,Woodruff JD,Rosenshein NB

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVE:In the present study we detected 72-kDa metalloproteinase expression in our series of early stage cervical carcinomas and analyzed the relationship between 72-kDa metalloproteinase staining and risk of nodal involvement with the goal of identifying a parameter useful in predicting the metastatic potential of ...

journal_title：Gynecologic oncology

authors： Garzetti GG,Ciavattini A,Lucarini G,Goteri G,Romanini C,Biagini G

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:Ovarian cancer is most frequently diagnosed at a late stage with a poor prognosis. No markers for early diagnosis have been established. Aberrantly methylated DNA appears as a promising molecular cancer marker. The aim of this study was to analyze the methylation status of the proapoptotic cancer related gene...

journal_title：Gynecologic oncology

authors： Häfner N,Diebolder H,Jansen L,Hoppe I,Dürst M,Runnebaum IB

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to determine whether the length of the interval from primary surgery to commencement of chemotherapy has any direct effect on progression-free survival in ovarian cancer. METHODS:The progression-free survival of 472 patients enrolled in four trials who had all received platin...

journal_title：Gynecologic oncology

authors： Flynn PM,Paul J,Cruickshank DJ,Scottish Gynaecological Cancer Trials Group.

更新日期：2002-09-01 00:00:00

abstract：:Forty-three patients with ovarian cancer were entered on this trial and treated with intravenous (iv) cyclophosphamide (C) and doxorubicin (A), and intraperitoneal (ip) cisplatin (DDP), every 21 days for eight cycles. Following iv hydration, the cisplatin was administered through an intraperitoneal catheter in 2 L of ...

journal_title：Gynecologic oncology

authors： Morgan RJ Jr,Braly P,Cecchi G,Leong L,Shibata S,Margolin K,Somlo G,McNamara M,Longmate J,Schinke S,Raschko J,Nagasawa S,Kogut N,Parker P,Stein A,Cho J,Smith E,Coluzzi P,Najera L,Johnson D,Womack E,Doroshow JH

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:Cone margin status has been reported to be the most important predictor of residual disease in patients with cervical intraepithelial neoplasia (CIN) undergoing electrosurgical excisional treatment. The primary aim of this study of patients treated with electrosurgical conization was to evaluate the associati...

journal_title：Gynecologic oncology

authors： Costa S,De Nuzzo M,Infante FE,Bonavita B,Marinelli M,Rubino A,Rambelli V,Santini D,Cristiani P,Bucchi L

更新日期：2002-04-01 00:00:00

abstract：:The presence of oncogenic HPV DNAs (HPV-16/18) in cervical carcinomas and their normal and metastatic pelvic lymph nodes and the expression patterns of proliferating cell nuclear antigen (PCNA) in cervical carcinomas were retrospectively studied to elucidate the possible roles of them in malignant transformation and p...

journal_title：Gynecologic oncology

authors： Park JS,Rhyu KS,Kim CJ,Kim HS,Han KT,Ahn HK,Kim SJ,Namkoong SE

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:We seek to describe the procedure, complications, and functional outcomes of utilizing the cecum and ascending colon for creation of a neovagina on a gynecologic oncology service. METHODS:A search of all the cases on the gynecologic oncology service over a ten year period yielded fourteen cases of cecal neov...

journal_title：Gynecologic oncology

authors： Khulpateea BR,Silver DF

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:The presence of cardiac metastasis from cervical carcinoma is extremely rare. The diagnosis is made almost exclusively postmortem. There are few cases of premortem diagnosis, and it is believed that when cardiac metastasis are found in vivo, the prognosis is extremely poor. Due to the rarity of this conditio...

journal_title：Gynecologic oncology

authors： Lemus JF,Abdulhay G,Sobolewski C,Risch VR

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Timely hospice referral is an essential component of quality end-of-life care, although a growing body of research suggests that for patients with various types of cancer, hospice referrals often occur very late in the course of care, and are marked by sociodemographic disparities. However, little is known a...

journal_title：Gynecologic oncology

authors： Fairfield KM,Murray KM,Wierman HR,Han PK,Hallen S,Miesfeldt S,Trimble EL,Warren JL,Earle CC

更新日期：2012-04-01 00:00:00

abstract：:This study evaluated the effects of cisplatin on 18 nerve conduction parameters of median, ulnar, peroneal, and sural nerves in relation to age, magnesium nadir, average magnesium, and magnesium replacement in gynecologic oncology patients. The 37 patients in this study received cisplatin (70 mg/m2) at 4-week interval...

journal_title：Gynecologic oncology

authors： Ashraf M,Riggs JE,Wearden S,Scotchel P

更新日期：1990-04-01 00:00:00