Detection of beta-subunit human chorionic gonadotropin mRNA in the peripheral blood of patients with nonmetastatic gestational trophoblastic disease.

abstract：:Despite high initial response rates to platinum-based chemotherapy, most patients with advanced ovarian carcinoma die of drug-resistant disease. Drug resistance can be overcome in the hematologic malignancies and lymphomas with high-dose therapy and bone marrow transplantation (BMT) when used early, suggesting that th...

journal_title：Gynecologic oncology

authors： Stiff P,Bayer R,Camarda M,Tan S,Dolan J,Potkul R,Loutfi S,Kinch L,Sosman J,Peace D

更新日期：1995-06-01 00:00:00

abstract：:Choriocarcinoma of the nonmolar placenta is presumptively a rare entity and is usually associated with widespread maternal metastases at the time of diagnosis. Nonmetastatic disease goes unrecognized and undiagnosed because placental carcinoma can be limited to a few villi, and grossly evident disease is often misinte...

journal_title：Gynecologic oncology

authors： Christopherson WA,Kanbour A,Szulman AE

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to analyze risk factors for septic complications during adjuvant chemotherapy and their impact on survival in patients with advanced epithelial ovarian cancer treated with neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS). METHODS:We retrospectively revie...

journal_title：Gynecologic oncology

authors： Son JH,Lee JH,Jung JA,Kong TW,Paek J,Chang SJ,Ryu HS

更新日期：2018-10-01 00:00:00

abstract：:A patient with endometrial carcinoma metastatic to the groin has had serial cytosol estrogen (ERc) and progestin (PRc) receptor determinations during hormonal therapy. The primary lesion was well differentiated and a left iliac node metastasis had high ERc and borderline PRc levels. PRc levels increased substantially ...

journal_title：Gynecologic oncology

authors： Schwartz PE,MacLusky N,Naftolin F,Eisenfeld A

更新日期：1983-08-01 00:00:00

abstract：:Sixty-eight patients with FIGO stage I, grade 2 or 3 adenocarcinoma of the endometrium were treated according to a protocol involving 10 Gy external pelvic irradiation, prompt hysterectomy with surgical staging, and postoperative therapy individualized according to surgical-pathologic findings. Five-year survival for ...

journal_title：Gynecologic oncology

authors： Shimm DS,Wang CC,Fuller AF Jr,Nelson JH Jr,Nikrui N,Young RH,Scully RE

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVE:To determine if DNA ploidy, hormone receptors, vascular space invasion (VSI), perivascular lymphocytes (PVL), and the oncogenes HER-2/neu, p53, and bcl-2 are independent prognostic indicators for lymph node metastasis and cancer recurrence in clinical stage I endometrial carcinoma. METHODS:Among 349 patients...

journal_title：Gynecologic oncology

authors： Bell JG,Minnick A,Reid GC,Judis J,Brownell M

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:To identify molecular prognosticators and therapeutic targets for high-grade serous epithelial ovarian cancers (EOCs) using genetic analyses driven by biologic features of EOC pathogenesis. METHODS:Ovarian tissue samples (n = 172; 122 serous EOCs, 30 other EOCs, 20 normal/benign) collected prospectively from...

journal_title：Gynecologic oncology

authors： Karlan BY,Dering J,Walsh C,Orsulic S,Lester J,Anderson LA,Ginther CL,Fejzo M,Slamon D

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine whether there is a link between integrins and components of the plasminogen system, regarding tumor cell invasion to the artificial extracellular matrix. METHODS:Immunocytochemistry was performed with antibodies directed against integrins alpha2beta1, alpha4beta1,...

journal_title：Gynecologic oncology

authors： Prifti S,Zourab Y,Koumouridis A,Bohlmann M,Strowitzki T,Rabe T

更新日期：2002-01-01 00:00:00

abstract：:Results of treatment and potential prognostic factors in 54 patients with clinical stage II endometrial carcinoma were analyzed. During the period analyzed, three different treatment techniques were used. The highest cure rate (70.6%) was observed in patients treated with simple hysterectomy and bilateral salpingo-oop...

journal_title：Gynecologic oncology

authors： Andersen ES

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVES:To refine models to predict surgical morbidity and 90-day mortality after primary debulking surgery (PDS) for advanced epithelial ovarian cancer (EOC). METHODS:Women with stage IIIC/IV EOC who underwent PDS with curative intent between 1/2/2003 and 12/30/2011 were included. Patient characteristics, intraope...

journal_title：Gynecologic oncology

authors： Kumar A,Janco JM,Mariani A,Bakkum-Gamez JN,Langstraat CL,Weaver AL,McGree ME,Cliby WA

更新日期：2016-01-01 00:00:00

abstract：:Techniques for sentinel lymph node injections have varied over the years in both cervical and uterine malignancy lymph node mapping. There remains considerable variation in techniques, particularly for uterine malignancies. This review summarizes some of the techniques that have been published and are currently utiliz...

journal_title：Gynecologic oncology

authors： Abu-Rustum NR,Khoury-Collado F,Gemignani ML

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:In 2008 GROINSS-V-I, the largest validation trial on the sentinel node (SN) procedure in vulvar cancer, showed that application of the SN-procedure in patients with early-stage vulvar cancer is safe. The current study aimed to evaluate long-term follow-up of these patients regarding recurrences and survival. ...

journal_title：Gynecologic oncology

authors： Te Grootenhuis NC,van der Zee AG,van Doorn HC,van der Velden J,Vergote I,Zanagnolo V,Baldwin PJ,Gaarenstroom KN,van Dorst EB,Trum JW,Slangen BF,Runnebaum IB,Tamussino K,Hermans RH,Provencher DM,de Bock GH,de Hullu JA,Oo

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To test whether platelets could increase invasion potential and initiate EMT in ovarian cancer cells via a TGF-β signaling pathway. METHODS:Blood samples were collected in 69 patients with ovarian cancer, 16 patients with benign ovarian tumor and 64 healthy donors. SK-OV-3 and OVCAR-3 ovarian cancer cells we...

journal_title：Gynecologic oncology

authors： Guo Y,Cui W,Pei Y,Xu D

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVES:Vaginal reconstruction following pelvic exenteration is an important aspect of the physical and psychological rehabilitation of women after radical surgery for pelvic malignancies. The choice of techniques is vast, and proper patient and surgical selection is important for obtaining satisfactory functional a...

journal_title：Gynecologic oncology

authors： Mirhashemi R,Averette HE,Lambrou N,Penalver MA,Mendez L,Ghurani G,Salom E

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVES:To clarify the anatomy necessary for the nerve sparing Okabayashi's radical hysterectomy, we meticulously separated the blood vessels and connective tissues to preserve the pelvic splanchnic nerve, the hypogastric nerve, and the bladder branch of the inferior hypogastric plexus under magnification (x2.5) dur...

journal_title：Gynecologic oncology

authors： Fujii S,Takakura K,Matsumura N,Higuchi T,Yura S,Mandai M,Baba T,Yoshioka S

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To profile long non-coding RNA (lncRNA) expression at the various anatomic sites of high-grades serous carcinoma (HGSC) and in effusion-derived exosomes. METHODS:LncRNA profiling was performed on 60 HGSC specimens, including 10 ovarian tumors, 10 solid metastases and 10 malignant effusions, as well as exosom...

journal_title：Gynecologic oncology

authors： Filippov-Levy N,Cohen-Schussheim H,Tropé CG,Hetland Falkenthal TE,Smith Y,Davidson B,Reich R

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Leiomyosarcoma (LMS) of the uterus is a rare neoplasm with an aggressive growth pattern. Although the majority of uterine LMS is diagnosed with disease confined to the uterus, the rate of recurrent disease is high. The most common sites of recurrent disease are lung, liver, and peritoneal cavity. The rate of...

journal_title：Gynecologic oncology

authors： Sandruck J,Escobar P,Lurain J,Fishman D

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Rectal tumors are rarely metastatic. Moreover, hematogenous spread is rare in ovarian cancer whose dissemination frequently occurs through peritoneal or lymphatic ways. CASE:A 55-year-old female presented with a rectal metastasis that appeared 20 years after the treatment of a primary clear cell carcinoma o...

journal_title：Gynecologic oncology

authors： Trastour C,Rahili A,Schumacker C,Effi AB,Bernard JL

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVES:Participation in clinical and basic science research is emphasized in gynecologic oncology training. We sought to identify trends in adherence to expected research practices and reasons for non-adherence among gynecologic oncology fellows. METHODS:An anonymous 31-question online survey assessing academic be...

journal_title：Gynecologic oncology

authors： Moulton LJ,Michener CM,Levinson K,Cobb L,Tseng J,Jernigan A

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:The ovarian yolk sac tumor (OYST) is a very rare malignancy arising in young women. Our objective was to determine whether an early decline in serum alpha-fetoprotein (AFP) during chemotherapy has a prognostic impact. METHODS:This retrospective study is based on prospectively recorded OYST cases at Gustave ...

journal_title：Gynecologic oncology

authors： de la Motte Rouge T,Pautier P,Genestie C,Rey A,Gouy S,Leary A,Haie-Meder C,Kerbrat P,Culine S,Fizazi K,Lhommé C

更新日期：2016-09-01 00:00:00

abstract：:Pretreatment serum levels of the tumor-associated antigens CA-125, tissue polypeptide antigen (TPA), carcinoembryonic antigen (CEA), and placental alkaline phosphatase (PLAP) were analyzed in 142 patients with epithelial ovarian carcinoma, and related to clinical and histopathological parameters. In a linear multiple ...

journal_title：Gynecologic oncology

authors： Tholander B,Taube A,Lindgren A,Sjöberg O,Stendahl U,Tamsen L

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:To determine whether squamous cervical cancers exhibit mutations or deletions in MHC class I genes or transport-associated protein (TAP) genes. METHODS:Polymerase chain reaction based protocols were used to examine HLA class I and TAP genes in a panel of cervical tumours, using DNA from corresponding blood s...

journal_title：Gynecologic oncology

authors： Fowler NL,Frazer IH

更新日期：2004-03-01 00:00:00

abstract：:In patients with small central recurrences following radiation therapy for cervical cancer the surgeon may have to make a judgment as to when radical hysterectomy is preferable to exenteration. During the years 1968-1984 there were 21 radical hysterectomies performed at Memorial Sloan-Kettering Cancer Center for recur...

journal_title：Gynecologic oncology

authors： Rubin SC,Hoskins WJ,Lewis JL Jr

更新日期：1987-07-01 00:00:00

abstract：OBJECTIVE:We assessed the antineoplastic effect and adverse reactions of paclitaxel monotherapy with paclitaxel 210 mg/m(2) given every 3 weeks by 3-h infusion on patients with endometrial cancer given as a 3-h infusion. METHODS:This study was a multi-center, open-label phase II clinical trial of paclitaxel 210 mg/m(2...

journal_title：Gynecologic oncology

authors： Hirai Y,Hasumi K,Onose R,Kuramoto H,Kuzuya K,Hatae M,Ochiai K,Nozawa S,Noda K

更新日期：2004-08-01 00:00:00

abstract：:A retrospective evaluation of 87 cases of uterine sarcoma treated during 1965-1980 at two Swedish hospitals has been made. Adjuvant postoperative radiotherapy has been compared with adjuvant chemotherapy. Various types of combination treatments were also evaluated. Both types of adjuvant therapy seem to reduce the fai...

journal_title：Gynecologic oncology

authors： Sorbe B

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVES:Most ovarian cancer patients are diagnosed at an advanced stage (67%) and prospects for significant improvement in survival reside in early diagnosis. While expression patterns of a recently identified biomarker family, microRNA, appear to be characteristic of tumor type and developmental origin, microRNA pr...

journal_title：Gynecologic oncology

authors： Taylor DD,Gercel-Taylor C

更新日期：2008-07-01 00:00:00

abstract：:A patient with a history of ovarian carcinoma that had responded well to cisplatin was treated with platinum agents for a recurrence. She had a seizure while receiving carboplatin and was switched to cisplatin. The patient was premedicated with antihistamines and steroids. After approximately 400 micrograms of cisplat...

journal_title：Gynecologic oncology

authors： Zweizig S,Roman LD,Muderspach LI

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:Borderline tumor of the ovary is an epithelial tumor with a low rate of growth and a low potential to invade or metastasize. This review will outline the most recent information regarding the molecular pathogenesis, pathology, fertility and tumor recurrence rate after conservative management of young women wi...

journal_title：Gynecologic oncology

authors： Tinelli R,Tinelli A,Tinelli FG,Cicinelli E,Malvasi A

更新日期：2006-01-01 00:00:00

abstract：:Flow cytometric cell cycle analysis was performed on paraffin-embedded blocks from 49 patients with stage I endometrial carcinoma. Care was taken to separate tumor tissue from normal tissue in each specimen; normal tissue was used as a control for each individual specimen. DNA index, proliferative activity, and cell D...

journal_title：Gynecologic oncology

authors： Vecek N,Nola M,Marusić M,Babić D,Uzarević B,Sabioncello A,Petrovecki M,Ljubić-Racunica N,Marinović T

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:Potential predictive/prognostic angiogenic markers were prospectively examined in a phase II trial of bevacizumab in epithelial ovarian cancer (EOC)/primary peritoneal cancer (PPC). METHODS:Recurrent/persistent EOC/PPC patients were treated with bevacizumab (15 mg/kg IV q21days) until disease progression. Va...

journal_title：Gynecologic oncology

authors： Han ES,Burger RA,Darcy KM,Sill MW,Randall LM,Chase D,Parmakhtiar B,Monk BJ,Greer BE,Connelly P,Degeest K,Fruehauf JP

更新日期：2010-12-01 00:00:00