Indole alkaloids from the leaves of Philippine Alstonia scholaris.

Abstract:

:The first seco-uleine alkaloids, manilamine (1) (18-hydroxy-19,20-dehydro-7,21-seco-uleine) and N4-methyl angustilobine B (2), were isolated from the (pH 5) alkaloid extract of Philippine Alstonia scholaris leaves together with the known indole alkaloids 19,20-(E)-vallesamine (3), angustilobine B N4-oxide (4), 20(S)-tubotaiwine (5), and 6,7-seco-angustilobine B (6). The structure of the alkaloids was established from MS and NMR experiments.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Macabeo AP,Krohn K,Gehle D,Read RW,Brophy JJ,Cordell GA,Franzblau SG,Aguinaldo AM

doi

10.1016/j.phytochem.2005.02.018

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

1158-62

issue

10

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(05)00082-8

journal_volume

66

pub_type

杂志文章
  • Investigating the conservation pattern of a putative second terpene synthase divalent metal binding motif in plants.

    abstract::Terpene synthases (TPS) require divalent metal ion co-factors, typically magnesium, that are bound by a canonical DDXXD motif, as well as a putative second, seemingly less well conserved and understood (N/D)DXX(S/T)XXXE motif. Given the role of the Ser/Thr side chain hydroxyl group in ligating one of the three catalyt...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2008.12.022

    authors: Zhou K,Peters RJ

    更新日期:2009-02-01 00:00:00

  • Reassessment of effects on lignification and vascular development in the irx4 Arabidopsis mutant.

    abstract::The Arabidopsis thaliana irregular xylem4 (irx4) cinnamoyl-CoA reductase 1 (CCR1) mutant was reassessed for its purported exclusive rate-limiting or key effects on lignification. Analyses of gross growth characteristics and stem cross-section anatomy, from seedling emergence to senescence, revealed that stunted irx4 m...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2004.12.016

    authors: Patten AM,Cardenas CL,Cochrane FC,Laskar DD,Bedgar DL,Davin LB,Lewis NG

    更新日期:2005-09-01 00:00:00

  • (+/-)-Dievodialetins A-G: Seven pairs of enantiomeric coumarin dimers with anti-acetylcholinesterase activity from the roots of Evodia lepta Merr.

    abstract::Seven pairs of undescribed enantiomeric bis-coumarins, (±)-dievodialetins A-G, were separated from the roots of Evodia lepta Merr. Two coumarin nuclei were linked via a 1,4-dimethyl4-vinylcyclohexene moiety in (±)-dievodialetins C-G. The structures of the undescribed compounds, including their absolute configurations ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2020.112597

    authors: Huang GY,Cui H,Lu XY,Zhang LD,Ding XY,Wu JJ,Duan LX,Zhang SJ,Liu Z,Zhang RR

    更新日期:2021-02-01 00:00:00

  • Antifungal highly oxygenated guaianolides and other constituents from Ajania fruticulosa.

    abstract::Three highly oxygenated guaianolides were isolated from the aerial parts of Ajania fruticulosa along with 17 known phytochemicals including a triterpene (alpha-amyrin), two plant sterols (beta-sitosterol, daucosterol), four flavonoids (axillarin, centaureidin, santin and 5,7,4'-trihydroxy-3,3'-dimethoxyflavone), and t...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(01)00389-2

    authors: Meng JC,Hu YF,Chen JH,Tan RX

    更新日期:2001-12-01 00:00:00

  • Dynamic flux cartography of hairy roots primary metabolism.

    abstract::A dynamic model for plant cell and hairy root primary metabolism is presented. The model includes nutrient uptake (Pi, sugars, nitrogen sources), the glycolysis and pentose phosphate pathways, the TCA cycle, amino acid biosynthesis, respiratory chain, biosynthesis of cell building blocks (structural hexoses, organic a...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2007.04.028

    authors: Cloutier M,Perrier M,Jolicoeur M

    更新日期:2007-08-01 00:00:00

  • Gibberellin oxidase activities in Bradyrhizobium japonicum bacteroids.

    abstract::Bradyrhizobium japonicum bacteroids isolated from root nodules of soybean (Glycine max.) plants converted the gibberellin (GA) precursor [(14)C1]GA12 into several products identified by combined gas chromatography-mass spectrometry as [(14)C1]GA24, [(14)C1]GA9, [(14)C1]GA15, GA9 17-nor-16-one and unidentified products...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2013.11.013

    authors: Méndez C,Baginsky C,Hedden P,Gong F,Carú M,Rojas MC

    更新日期:2014-02-01 00:00:00

  • Purification and properties of pi-repressible acid phosphatases from Aspergillus nidulans.

    abstract::Two forms of the pacA-encoded acid phosphatase (designated acid phosphatases I and II) secreted by the mold Aspergillus nidulans grown in low-Pi medium at 37 degrees, pH5.0, were purified to apparent homogeneity by PAGE. The M(r) of the purified enzyme forms were ca 115000 (60000) and 113000 (62000) respectively for f...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(98)00205-2

    authors: Nozawa SR,MacCheroni W Jr,Stábeli RG,Thedei G Jr,Rossi A

    更新日期:1998-11-20 00:00:00

  • Iridal glycosides from Iris spuria (Zeal), cultivated in Egypt.

    abstract::Fractionation of a methanol extract obtained from rhizomes of I. spuria (Zeal) resulted in the isolation of seven iridalglycosides 5a,b, 6a-c, 7, 8. The structures of the aglycons and the position of the glycosidic bonds were elucidated by spectroscopic analyses. The nature of the sugar moieties was determined as gluc...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(02)00110-3

    authors: Marner FJ,Singab AN,Al-Azizi MM,El-Emary NA,Schäfer M

    更新日期:2002-06-01 00:00:00

  • A cDNA clone for 3-carene synthase from Salvia stenophylla.

    abstract::The essential oil of Salvia stenophylla contains (+)-3-carene as the principal monoterpene component. Using an enriched cDNA library prepared from mRNA isolated from S. stenophylla peltate glandular trichomes, and a homology-based cloning strategy, a full-length cDNA was isolated that encoded a preprotein of 69.7 kDa ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(02)00674-x

    authors: Hoelscher DJ,Williams DC,Wildung MR,Croteau R

    更新日期:2003-04-01 00:00:00

  • A-type proanthocyanidin antioxidant from Dioclea lasiophylla.

    abstract::The A-type proanthocyanidin, epigallocatechin-(2beta-->7,4beta-->8)-epicatechin, together with the known epicatechin, luteolin 3'beta-D-glucopyranoside, chrysoeriol 7beta-D-glucopyranoside and 2-methylpentan-2,4-diol, were isolated from leaves of Dioclea lasiophilla. The structures were established on the basis of the...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)00297-1

    authors: Barreiros AL,David JP,de Queiroz LP,David JM

    更新日期:2000-12-01 00:00:00

  • Structural characterization and rheological properties of β-D-glucan from hull-less barley (Hordeum vulgare L. var. nudum Hook. f.).

    abstract::A high purity of β-D-glucan (80.8%) from hull-less barley (Hordeum vulgare L. var. nudum Hook. f.) (HBBG) was isolated by alkali extraction and multi-precipitation with ethanol. The molecular weight (Mw) of HBBG was determined as 571.4 kDa with a broad distribution (Mw/Mn = 1.6) by using HPSEC. According to methylatio...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2018.08.004

    authors: Zhang H,Zhang N,Xiong Z,Wang G,Xia Y,Lai P,Ai L

    更新日期:2018-11-01 00:00:00

  • The AOC promoter of tomato is regulated by developmental and environmental stimuli.

    abstract::The allene oxide cyclase (AOC) catalyzes the formation of cis-(+)-12-oxophytodienoic acid, an intermediate in jasmonate biosynthesis and is encoded by a single copy gene in tomato. The full length AOC promoter isolated by genome walk contains 3600 bp. Transgenic tomato lines carrying a 1000 bp promoter fragment and th...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2008.03.007

    authors: Stenzel I,Hause B,Proels R,Miersch O,Oka M,Roitsch T,Wasternack C

    更新日期:2008-06-01 00:00:00

  • An acidic amino acid-specific protease from germinating soybeans.

    abstract::The degradation of the beta-conglycinin protein reserves in soybean seeds during germination and early growth begins with the proteolysis of its alpha and alpha' subunits by an enzyme called Protease C1. In the pathway, a number of proteolytic intermediates are produced and subsequently degraded. Determination of the ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/0031-9422(95)00896-9

    authors: Tan-Wilson AL,Liu X,Chen R,Qi X,Wilson KA

    更新日期:1996-05-01 00:00:00

  • Identification of phenylamide phytoalexins and characterization of inducible phenylamide metabolism in wheat.

    abstract::Changes in specialized metabolites were analyzed in wheat leaves inoculated with Bipolaris sorokiniana, the causal agent of spot blotch of Poaceae species. HPLC analysis detected the accumulation of six compounds in B. sorokiniana-infected leaves. Of these, we purified two compounds by silica gel and ODS column chroma...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2019.112098

    authors: Ube N,Harada D,Katsuyama Y,Osaki-Oka K,Tonooka T,Ueno K,Taketa S,Ishihara A

    更新日期:2019-11-01 00:00:00

  • Indole alkaloids of Psychotria as multifunctional cholinesterases and monoamine oxidases inhibitors.

    abstract::Thirteen Psychotria alkaloids were evaluated regarding their interactions with acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and monoamine oxidases A and B (MAO-A and MAO-B), which are enzymatic targets related with neurodegenerative diseases. Two quaternary β-carboline alkaloids, prunifoleine and 14-oxop...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2012.11.015

    authors: Passos CS,Simões-Pires CA,Nurisso A,Soldi TC,Kato L,de Oliveira CM,de Faria EO,Marcourt L,Gottfried C,Carrupt PA,Henriques AT

    更新日期:2013-02-01 00:00:00

  • Cadinane sesquiterpenes from the mushroom Lyophyllum transforme.

    abstract::Two rare cadinane-type sesquiterpenes, lyophyllone A (1) and lyophyllanetriol A (2), were isolated from the mushroom Lyophyllum transforme. The structures were elucidated on the basis of exhaustive NMR techniques, together with MS, UV-Vis and molecular modelling. The absolute configuration of lyophyllone A was determi...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2013.03.019

    authors: Clericuzio M,Negri R,Cossi M,Gilardoni G,Gozzini D,Vidari G

    更新日期:2013-09-01 00:00:00

  • Developments in aspects of ecological phytochemistry: the role of cis-jasmone in inducible defence systems in plants.

    abstract::The challenges and opportunities for protecting agricultural production of food and other materials will be met through exploiting the induction of defence pathways in plants to control pests, diseases and weeds. These approaches will involve processes that can be activated by application of natural products, patented...

    journal_title:Phytochemistry

    pub_type: 杂志文章,评审

    doi:10.1016/j.phytochem.2007.09.025

    authors: Pickett JA,Birkett MA,Bruce TJ,Chamberlain K,Gordon-Weeks R,Matthes MC,Napier JA,Smart LE,Woodcock CM

    更新日期:2007-11-01 00:00:00

  • A bidesmosidic triterpene glycoside from the roots of Symphytum officinale.

    abstract::A new bidesmosidic triterpenoidal saponin of hederagenin was isolated from the ethanolic extract of the roots of Symphytum officinale L. Its structure was elucidated by using 1H NMR, 1H-1H COSY NMR, heteronuclear 1H-13C correlated spectroscopy (heteroCOSY), 13C NMR, DEPT, FAB mass spectrometry and chemical evidence as...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)97091-2

    authors: Noorwala M,Mohammad FV,Ahmad VU,Sener B

    更新日期:1994-05-01 00:00:00

  • Cytotoxic phenolic constituents from Hypericum japonicum.

    abstract::Nine undescribed compounds, including five xanthone derivatives, two flavonoids, one 2-pyrone derivative, and one undescribed naturally occurring compound, along with 30 known phenolic compounds, were isolated from Hypericum japonicum. In addition, hyperjaponols A and B were identified as racemates. The structures and...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2019.04.012

    authors: Zhu W,Qiu J,Zeng YR,Yi P,Lou HY,Jian JY,Zuo MX,Duan L,Gu W,Huang LJ,Li YM,Yuan CM,Hao XJ

    更新日期:2019-08-01 00:00:00

  • Silicon-mediated alleviation of Mn toxicity in Cucumis sativus in relation to activities of superoxide dismutase and ascorbate peroxidase.

    abstract::The effects of exogenous silicon (Si) on plant growth, activities of superoxide dismutase (SOD), guaiacol peroxidase (GPX), ascorbate peroxidase (APX), dehydroascorbate reductase (DHAR), glutathione reductase (GR) and catalase, and concentrations of ascorbate and glutathione were investigated in cucumber (Cucumis sati...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2005.05.006

    authors: Shi Q,Bao Z,Zhu Z,He Y,Qian Q,Yu J

    更新日期:2005-07-01 00:00:00

  • Secondary products in mycorrhizal roots of tobacco and tomato.

    abstract::Colonization of the roots of various tobacco species and cultivars (Nicotiana glauca Grah., N. longiflora Cav., N. rustica L., N. tabacum L., N. tabacum L. cv. Samsun NN, N. sanderae hort. Sander ex Wats.) as well as tomato plants (Lycopersicon esculentum L. cv. Moneymaker) by the arbuscular mycorrhizal fungus Glomus ...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)00047-9

    authors: Maier W,Schmidt J,Nimtz M,Wray V,Strack D

    更新日期:2000-06-01 00:00:00

  • Withanolides from aerial parts of Nicandra physalodes.

    abstract::Twenty withanolides, including previously unknown nicanlodes A-M, were isolated from aerial parts of Nicandra physalodes. Their structural elucidations were unambiguously achieved through interpretation of extensive spectroscopic data (NMR and HRMS) and by comparison with literature data. Nicanlodes A and B have an un...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2017.02.009

    authors: Yu MY,Zhao GT,Liu JQ,Khan A,Peng XR,Zhou L,Dong JR,Li HZ,Qiu MH

    更新日期:2017-05-01 00:00:00

  • Actinidin, a protease from kiwifruit, induces changes in morphology and adhesion of T84 intestinal epithelial cells.

    abstract::Actinidin belongs to the papain-like family of cysteine proteases and is a major kiwifruit allergen. In this study, the effect of actinidin on cellular morphology and adhesion of T84 intestinal cells was investigated. Both rounding and detachment of T84 cells were observed upon actinidin treatment. The morphological c...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2011.12.014

    authors: Čavić M,Grozdanović M,Bajić A,Srdić-Rajić T,Anđjus PR,Gavrović-Jankulović M

    更新日期:2012-05-01 00:00:00

  • Alpha-amylase from mung beans (Vigna radiata)--correlation of biochemical properties and tertiary structure by homology modelling.

    abstract::Alpha-amylase from germinated mung beans (Vigna radiata) has been purified 600-fold to electrophoretic homogeneity and a final specific activity of 437 U/mg. SDS-PAGE of the final preparation revealed a single protein band of 46 kDa. The optimum pH was 5.6. The energy of activation was determined to be 7.03 kcal/mol i...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2007.04.006

    authors: Tripathi P,Lo Leggio L,Mansfeld J,Ulbrich-Hofmann R,Kayastha AM

    更新日期:2007-06-01 00:00:00

  • A bidesmosidic hederagenin hexasaccharide from the roots of Symphytum officinale.

    abstract::A new bidesmosidic triterpenoidal saponin 3-O-[beta-D-glucopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->4)-alpha-L - arabinopyranosyl]-hederagenin-28-O-[alpha-L-rhamnopyranosyl- (1-->4)-beta-D- glucopyranosyl-(1-->6)-beta-D-glucopyranosyl] ester, was isolated from the roots of Symphytum officinale. The structure was a...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/0031-9422(95)00246-4

    authors: Mohammad FV,Noorwala M,Ahmad VU,Sener B

    更新日期:1995-09-01 00:00:00

  • 28-Noroleanane-derived spirocyclic triterpenoids and iridoid glucosides from the roots of Phlomoides umbrosa (Turcz.) Kamelin & Makhm with their cytotoxic effects.

    abstract::Four undescribed 23,24-O-isopropylidene-19(18 → 17)-abeo-28-noroleanane-derived spirocyclic triterpenoids and an undescribed 28-noroleanane-derived spirocyclic triterpenoid, together with five known 28-noroleanane-derived spirocyclic triterpenoids, were isolated and identified. In addition, three undescribed iridoid g...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2018.06.003

    authors: Le DD,Nguyen DH,Zhao BT,Kim JA,Kim SK,Min BS,Choi JS,Woo MH

    更新日期:2018-09-01 00:00:00

  • Does an apple a day keep the doctor away because a phytoestrogen a day keeps the virus at bay? A review of the anti-viral properties of phytoestrogens.

    abstract::From dengue to herpes and influenza to AIDS, the phytoestrogens that are present in many fruits and vegetables have been shown to exert anti-viral properties. Here we review the various different anti-viral mechanisms employed by phytoestrogens. ...

    journal_title:Phytochemistry

    pub_type: 杂志文章,评审

    doi:10.1016/j.phytochem.2006.11.018

    authors: Martin JH,Crotty S,Warren P,Nelson PN

    更新日期:2007-02-01 00:00:00

  • On the formation of lignin polysaccharide networks in Norway spruce.

    abstract::In this study we were mirroring suggested in vivo phenomena of lignin-hemicellulose complex formation in vitro, by cross-linking Norway spruce (Picea abies) galactoglucomannans, xylans and lignin moieties to high molecular weight complexes by laccase treatment. We were able to observe the oxidation and cross-linking o...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/j.phytochem.2014.10.027

    authors: Oinonen P,Zhang L,Lawoko M,Henriksson G

    更新日期:2015-03-01 00:00:00

  • Ginsenosides from American ginseng: chemical and pharmacological diversity.

    abstract::Ginseng occupies a prominent position in the list of best-selling natural products in the world. Compared to the long history of use and widespread research on Asian ginseng, the study of American ginseng is relatively limited. In the past decade, some promising advances have been achieved in understanding the chemist...

    journal_title:Phytochemistry

    pub_type: 杂志文章,评审

    doi:10.1016/j.phytochem.2011.02.012

    authors: Qi LW,Wang CZ,Yuan CS

    更新日期:2011-06-01 00:00:00

  • Kaempferol triosides from Reseda muricata.

    abstract::A flavonoid trioside and its coumaryl ester together with seven known flavonoids and five phenolic acids were isolated from the leaves of Reseda muricata. Their structures were elucidated by spectroscopic methods including UV, FAB MS, 1H, 13C and 2D-NMR, DEPT, HMBC and HMQC experiments. The two compounds were identifi...

    journal_title:Phytochemistry

    pub_type: 杂志文章

    doi:10.1016/s0031-9422(00)00479-9

    authors: El-Sayed NH,Omara NM,Yousef AK,Farag AM,Mabry TJ

    更新日期:2001-06-01 00:00:00