N-Substituted acridone alkaloids from Toddaliopsis bremekampii (Rutaceae: Toddalioideae) of south-central Africa.

Abstract:

:Toddaliopsins A-D, four novel 1,2,3-trioxygenated acridone alkaloids, have been isolated from the leaves of Toddaliopsis bremekampii. Toddaliopsins B-D are the first reported acridone alkaloids with substituted N-methyl groups, in the light of which the chemotaxonomic relationship of Toddaliopsis and Vepris is discussed. Toddaliopsin C possesses moderate anti-inflammatory activity, which may be related to the hydroxy group present at C-1.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Naidoo D,Coombes PH,Mulholland DA,Crouch NR,van den Bergh AJ

doi

10.1016/j.phytochem.2005.04.036

subject

Has Abstract

pub_date

2005-07-01 00:00:00

pages

1724-8

issue

14

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(05)00211-6

journal_volume

66

pub_type

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