Euphane triterpenoids of Cassipourea lanceolata from the Madagascar rainforest.

Abstract:

:Fractionation of an ethanol extract of a Madagascar collection of the leaves and fruit of Cassipourea lanceolata Tul. led to the isolation of three euphane triterpenoids 1-3. The (1)H and (13)C NMR spectra of all compounds were fully assigned using a combination of 2D NMR experiments, including COSY, TOCSY, HSQC (HMQC), HMBC and ROESY sequences. The three compounds showed weak antiproliferative activities against the A2780 human ovarian cancer cell line, with IC(50) values of 25, 25 and 32 microM, respectively.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Hou Y,Cao S,Brodie PJ,Miller JS,Birkinshaw C,Andrianjafy MN,Andriantsiferana R,Rasamison VE,TenDyke K,Shen Y,Suh EM,Kingston DG

doi

10.1016/j.phytochem.2009.12.009

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

669-74

issue

5-6

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(09)00545-7

journal_volume

71

pub_type

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