Jubanines F-J, cyclopeptide alkaloids from the roots of Ziziphus jujuba.

Abstract:

:Five Ib-type cyclopeptide alkaloids, jubanines F-J (1-5), and three known compounds, nummularine B (6), daechuine-S3 (7), and mucronine K (8) were isolated from the roots of Ziziphus jujuba. Their structures were fully characterized by spectroscopic analyses in combination with chemical derivatization. Compounds 1-3, and 6 were evaluated for their antiviral activity against the porcine epidemic diarrhea virus (PEDV). Compounds 2, 3, and 6 showed potent inhibitory effects on PEDV replication.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Kang KB,Ming G,Kim GJ,Ha TK,Choi H,Oh WK,Sung SH

doi

10.1016/j.phytochem.2015.09.001

subject

Has Abstract

pub_date

2015-11-01 00:00:00

pages

90-5

eissn

0031-9422

issn

1873-3700

pii

S0031-9422(15)30080-7

journal_volume

119

pub_type

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