ent-Kaurene diterpenoids from Isodon oresbius.

Abstract:

:Three new ent-kaurene diterpenoids, oreskaurins A-C (1-3), together with ten known ent-kaurene diterpenoids, enmenin monoacetate (4), effusanin E (5), adenolin B (6), maoecrystal G (7), enmelol (8), trichokaurin (9), sodoponin (10), trichorabdal A (11), nodosin (12), enmein (13), and a flavonoid, vitexin (14), were isolated from Isodon oresbius. Their structures were determined by spectroscopic means. Compound 12 showed inhibitory activity toward K562 cells with IC(50)=1.43 microg/ml.

journal_name

Phytochemistry

journal_title

Phytochemistry

authors

Xiang W,Li RT,Wang ZY,Li SH,Zhao QS,Zhang HJ,Sun HD

doi

10.1016/j.phytochem.2004.02.022

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

1173-7

issue

8

eissn

0031-9422

issn

1873-3700

pii

S0031942204000962

journal_volume

65

pub_type

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