Application of a DNA double labelling method for the flow cytometric analysis of recruitment of non-cycling cells in a mixed population of P and Q cells.

abstract：OBJECTIVES:Dental follicle cells (DFCs) provide the origin of periodontal tissues, and Runx2 is essential for bone formation and tooth development. In this study, pluripotency of DFCs was evaluated and effects of Runx2 on them were investigated. MATERIALS AND METHODS:The DFCs were induced to differentiate towards oste...

journal_title：Cell proliferation

authors： Pan K,Sun Q,Zhang J,Ge S,Li S,Zhao Y,Yang P

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVES:The present study aimed to investigate overall effect of quercetin on proliferation and osteogenic differentiation of mouse adipose stem cells (mASCs) in vitro. MATERIALS AND METHODS:Mouse adipose stem cells were isolated from subcutaneous fat pads and induced into the osteogenic lineage. Effects of quercet...

journal_title：Cell proliferation

authors： Zhou C,Lin Y

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:Glucagon-like peptide 2 (GLP2) is involved in the regulation of energy absorption and metabolism. Despite the importance of the GLP2 signalling mechanisms on osteoclast, little has been studied on how GLP2 works during osteoclastogenesis. MATERIALS AND METHODS:RAW264.7 cells were infected with rLV-Green-GLP...

journal_title：Cell proliferation

authors： Lu Y,Lu D,Hu Y

更新日期：2018-08-01 00:00:00

abstract：:The human promyelocytic leukaemia cell line, HL-60, was investigated with regard to proliferation and terminal differentiation following irradiation. The cells were X-irradiated and induced with 1.25% dimethyl sulfoxide (DMSO) towards the granulocytic lineage. Proliferation was measured via cell growth, clonogenicity ...

journal_title：Cell proliferation

authors： Sendler A,Kaffenberger W,Nuyken I,van Beuningen D

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVES:It has been widely reported that maternal diabetes impairs oocyte quality. However, the responsible mechanisms remain to be explored. In the present study, we focused on whether SIRT3-GSK3β pathway mediates the meiotic defects in oocytes from diabetic mice. MATERIALS AND METHODS:GSK3β functions in mouse ooc...

journal_title：Cell proliferation

authors： Xin Y,Jin Y,Ge J,Huang Z,Han L,Li C,Wang D,Zhu S,Wang Q

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:Somatic stem cells can be obtained from a variety of adult human tissues. However, it was not clear whether human parathyroid glands, which secrete parathyroid hormones and are essential in maintaining homeostasis levels of calcium ions in the circulation, contained stem cells. We aimed to investigate the po...

journal_title：Cell proliferation

authors： Shih YR,Kuo TK,Yang AH,Lee OK,Lee CH

更新日期：2009-08-01 00:00:00

abstract：:Natural compounds derived from plant sources are well characterized as possessing a wide variety of remarkable anti-tumour properties, for example modulating programmed cell death, primarily referring to apoptosis, and autophagy. Distinct from apoptosis, autophagy (an evolutionarily conserved, multi-step lysosomal deg...

journal_title：Cell proliferation

authors： Zhang X,Chen LX,Ouyang L,Cheng Y,Liu B

更新日期：2012-10-01 00:00:00

abstract：:Electromagnetic ultra-wideband pulses (UWB) or nanopulses, are generated by a wide range of electronic devices used in communications and radar technology. However, the specific effects of nanopulse exposure on cell growth and function have not been extensively investigated. Here, studies have been conducted to determ...

journal_title：Cell proliferation

authors： Sylvester PW,Shah SJ,Haynie DT,Briski KP

更新日期：2005-06-01 00:00:00

abstract：:Cell proliferation was investigated in human tumour xenografts using bromodeoxyuridine (BrdUrd) labelling, evaluated either by flow cytometry or in tissue sections, and also using the proliferation marker Ki-67. BrdUrd labelling was found to increase when cryostat tumour sections were digested with an enzymic solution...

journal_title：Cell proliferation

authors： Parkins CS,Bush C,Price P,Steel GG

更新日期：1991-03-01 00:00:00

abstract：OBJECTIVES:Worldwide, lung cancer accounts for the majority of cancer-related deaths. Aberrant expression of miRNAs has increasingly been reported to be associated with tumour progression. This study aimed to explore the role of miR-301b in regulating apoptosis in lung cancer. MATERIALS AND METHODS:Expression of miR-3...

journal_title：Cell proliferation

authors： Wu D,Chen B,Cui F,He X,Wang W,Wang M

更新日期：2016-08-01 00:00:00

abstract：:The signal transducers and activators of transcription--STAT5A and STAT5B--take part in the regulation of many essential physiopathological processes. They influence the cell cycle, apoptosis and the proliferation of different types of cell lines. The STAT5 proteins are induced in response to multiple haematopoietic c...

journal_title：Cell proliferation

authors： Baśkiewicz-Masiuk M,Masiuk M,Machaliński B

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:During human pregnancy, the endothelial cells of the uterine spiral arteries (SPA) are extensively replaced by a subtype of placental trophoblasts, endovascular extravillous trophoblasts (enEVTs), thus establishing a placental-maternal circulation. On this pathway, foetus-derived placental villi and enEVTs b...

journal_title：Cell proliferation

authors： Ma Y,Yang Q,Fan M,Zhang L,Gu Y,Jia W,Li Z,Wang F,Li YX,Wang J,Li R,Shao X,Wang YL

更新日期：2020-05-01 00:00:00

abstract：:Spontaneously proliferating human leucocytes have been characterized and enumerated using multiparameter flow cytometry. The frequency of spontaneously proliferating cells amongst human peripheral blood mononuclear cells, was determined on the basis of BrdUrd incorporation and total DNA content in samples of cells inc...

journal_title：Cell proliferation

authors： Johannisson A,Amnéus H

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVES:Oestrogen receptor (ER) is a common nucleus receptor that is essential for the regulation of cell growth, proliferation and differentiation. This study was to examine whether ERα can affect the proliferation and odonto/osteogenic differentiation of stem cells from apical papilla (SCAPs). MATERIALS AND METHO...

journal_title：Cell proliferation

authors： Wang Y,Lu Y,Li Z,Zhou Y,Gu Y,Pang X,Wu J,Gobin R,Yu J

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVES:Oestrogen is known to inhibit osteoclastogenesis, and numerous studies have identified it as an autophagic activator. To date, the role of oestrogen in the autophagy of osteoclast precursors (OCPs) during osteoclastogenesis remains unclear. This study aimed to determine the effect of autophagy regulated by t...

journal_title：Cell proliferation

authors： Cheng L,Zhu Y,Ke D,Xie D

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVES:Restoring a functional beta-cell mass is a fundamental goal in treating diabetes. A complex signalling pathway network coordinates the regulation of beta-cell proliferation, although a role for ERK5 in this network has not been reported. This question was addressed in this study. MATERIALS AND METHODS:We st...

journal_title：Cell proliferation

authors： Chen C,Wu S,Lin X,Wu D,Fischbach S,Xiao X

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:In humans, non-obstructive azoospermia (NOA) is a major cause of male infertility. However, the aetiology of NOA is largely unknown. Previous studies reported that protein CK2β was abundantly and broadly expressed in spermatogenic cells. Here, we investigate whether protein CK2β participates in spermatogenes...

journal_title：Cell proliferation

authors： Liang QX,Wang ZB,Lei WL,Lin F,Qiao JY,Filhol-Cochet O,Boldyreff B,Schatten H,Sun QY,Qian WP

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Accumulating evidence demonstrated that the long noncoding RNA (lncRNA) HOTAIR (Hox transcript antisense intergenic RNA) plays key role in renal cell carcinoma (RCC) malignancy, while microRNA-124 (miR-124) is a tumour suppressor in RCC. The aim of this work was to assess the biological function of HOTAIR an...

journal_title：Cell proliferation

authors： Pan Y,Wu Y,Hu J,Shan Y,Ma J,Ma H,Qi X,Jia L

更新日期：2018-12-01 00:00:00

abstract：:In order to determine the role of micromilieu in tumour spheroid growth, a mathematical model was developed to predict EMT6/Ro spheroid growth and microenvironment based upon numerical solution of the diffusion/reaction equation for oxygen, glucose, lactate ion, carbon dioxide, bicarbonate ion, chlorine ion and hydrog...

journal_title：Cell proliferation

authors： Casciari JJ,Sotirchos SV,Sutherland RM

更新日期：1992-01-01 00:00:00

abstract：:The human skin equivalent (HSE) is an in vitro reconstructed model that resembles skin morphologically and biochemically. The HSE is formed by overlaying a fibroblast-populated collagen matrix with a suspension of epidermal cells. Basal keratinocytes attach to the dermal equivalent via a newly formed basement membrane...

journal_title：Cell proliferation

authors： Graeter LJ,Hull BE

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVES:Enterochromaffin (EC) cells have been associated with functional gastrointestinal disorders such as IBS. Recently, we found that glial cell-derived neurotrophic factor (GDNF)-rearranged during transfection (RET) localized in EC cells in human colonic epithelia. Here, we examine the role of GDNF-RET in the pa...

journal_title：Cell proliferation

authors： Lin L,Feng B,Zhou R,Liu Y,Li L,Wang K,Yu Y,Liu C,Long X,Gu X,Li B,Wang X,Yang X,Cong Y,Zuo X,Li Y

更新日期：2020-10-01 00:00:00

abstract：:The effect of various GnRH analogues, and their conjugates on proliferation, clonogenicity and cell cycle phase distribution of MCF-7 and Ishikawa human cancer cell lines was studied. GnRH-III, a sea lamprey GnRH analogue reduced cell proliferation by 35% and clonogenicity by 55%. Structural modifications either decre...

journal_title：Cell proliferation

authors： Kálnay A,Pályi I,Vincze B,Mihalik R,Mezõ I,Pató J,Seprõdi J,Lovas S,Murphy RF

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVES:SAV1 is a human homologue of Salvador that contains two protein-protein interaction modules known as WW domains and acts as a scaffolding protein. SAV1 participates in the development of diverse types of cancer. We aimed to investigate the role of SAV1 in human colorectal cancer. MATERIALS AND METHODS:Human...

journal_title：Cell proliferation

authors： Jiang J,Chang W,Fu Y,Gao Y,Zhao C,Zhang X,Zhang S

更新日期：2017-08-01 00:00:00

abstract：:We have developed a mathematical model based on proliferation and infiltration of neoplastic cells that allows predictions to be made concerning the life expectancies following various extents of surgical resection of gliomas of all grades of malignancy. The key model parameters are the growth rate and the diffusion r...

journal_title：Cell proliferation

authors： Woodward DE,Cook J,Tracqui P,Cruywagen GC,Murray JD,Alvord EC Jr

更新日期：1996-06-01 00:00:00

abstract：:Studies on growth regulation in vitro to a large extent rely on comparison of growth curves. However, these do not discriminate between the relative contributions of the mitotic rate and the apoptotic rate to the net growth rate. In the present study, differential effects of 17beta-oestradiol (E2, 10(-8) M) and/or tam...

journal_title：Cell proliferation

authors： Budtz PE

更新日期：1999-10-01 00:00:00

abstract：OBJECTIVES:Advanced head and neck carcinomas (HNCs) are aggressive tumours, mainly due to hypoxia and a cancer stem cell (CSC) subpopulation. The aim of this study was to simulate tumour growth and behaviour during radiotherapy of three HNC groups (governed by different growth kinetics, hypoxia levels and CSC division ...

journal_title：Cell proliferation

authors： Marcu LG,Marcu D,Filip SM

更新日期：2016-06-01 00:00:00

abstract：:In the past few years, the paramount role of cancer stem cells (CSCs), in terms of cancer initiation, proliferation, metastasis, invasion and chemoresistance, has been revealed by accumulating studies. However, this level of cellular plasticity cannot be entirely explained by genetic mutations. Research on epigenetic ...

journal_title：Cell proliferation

authors： Zhang S,Gong Y,Li C,Yang W,Li L

更新日期：2020-12-13 00:00:00

abstract：:Nerous system diseases, both central and peripheral, bring an incredible burden onto patients and enormously reduce their quality of life. Currently, there are still no effective treatments to repair nerve lesions that do not have side effects. Stem cell-based therapies, especially those using dental stem cells, bring...

journal_title：Cell proliferation

authors： Wang D,Wang Y,Tian W,Pan J

更新日期：2019-05-01 00:00:00

abstract：:Recent epidemiological studies have demonstrated a correlation between regular aspirin (acetylsalicylic acid) use and decrease risk for the development of fatal colorectal cancer. An increase in the size of the cell proliferation compartment in colorectal crypts has been correlated with an increased risk for the devel...

journal_title：Cell proliferation

authors： Barnes CJ,Lee M,Hardman WE,Cameron IL

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVES:Skin-derived precursors are recognized to be a potentially autologous and accessible source of neural precursor cells for drug screening or cell-based treatments, in many neurological disorders. Thus, it is necessary to investigate appropriate methods for cryopreservation of such human skin-derived precursor...

journal_title：Cell proliferation

authors： Bakhtiari M,Mansouri K,Sadeghi Y,Mostafaie A

更新日期：2012-04-01 00:00:00