Deletion of Ck2β gene causes germ cell development arrest and azoospermia in male mice.

abstract：OBJECTIVES:miRNAs play crucial roles in human tumourigenesis. This study was performed to measure expression and function of miR-762 in breast cancer. MATERIALS AND METHODS:Expression of miR-762 in breast tissues and cell lines (SK-BR-3, DA-MB-435s, MCF-7 and MDA-MB-231, HBL-100) was measured by using real-time RT-PCR...

journal_title：Cell proliferation

authors： Li Y,Huang R,Wang L,Hao J,Zhang Q,Ling R,Yun J

更新日期：2015-12-01 00:00:00

abstract：:The human skin equivalent (HSE) is an in vitro reconstructed model that resembles skin morphologically and biochemically. The HSE is formed by overlaying a fibroblast-populated collagen matrix with a suspension of epidermal cells. Basal keratinocytes attach to the dermal equivalent via a newly formed basement membrane...

journal_title：Cell proliferation

authors： Graeter LJ,Hull BE

更新日期：1996-12-01 00:00:00

abstract：:The signal transducers and activators of transcription--STAT5A and STAT5B--take part in the regulation of many essential physiopathological processes. They influence the cell cycle, apoptosis and the proliferation of different types of cell lines. The STAT5 proteins are induced in response to multiple haematopoietic c...

journal_title：Cell proliferation

authors： Baśkiewicz-Masiuk M,Masiuk M,Machaliński B

更新日期：2003-10-01 00:00:00

abstract：:L-type voltage-gated calcium ion channels (L-VGCCs) have been demonstrated to be the mediator of several significant intracellular activities in excitable cells, such as neurons, chromaffin cells and myocytes. Recently, an increasing number of studies have investigated the function of L-VGCCs in non-excitable cells, p...

journal_title：Cell proliferation

authors： Tan YZ,Fei DD,He XN,Dai JM,Xu RC,Xu XY,Wu JJ,Li B

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:Steroid-induced osteonecrosis of the femoral head (ONFH) is a common orthopaedic disease of which early detection remains clinically challenging. Accumulating evidences indicated that circulating microRNAs (miRNAs) plays vital roles in the development of several bone diseases. However, the association betwee...

journal_title：Cell proliferation

authors： Li Z,Jiang C,Li X,Wu WKK,Chen X,Zhu S,Ye C,Chan MTV,Qian W

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Spinal cord tumours are highly malignant and often lead to paralysis and death due to their infiltrative nature, high recurrence rate and limited treatment options. In this study, we measured antitumour efficacy of the Salmonella typhimurium A1-R tumour-targeting bacterium strain, administered systemically or...

journal_title：Cell proliferation

authors： Kimura H,Zhang L,Zhao M,Hayashi K,Tsuchiya H,Tomita K,Bouvet M,Wessels J,Hoffman RM

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:MicroRNAs are powerful regulators in hepatocellular carcinoma (HCC) tumorigenesis. MicoRNA-191 (miR-191) has been reported to play an important role in HCC, However, the regulatory mechanism is still unclear. In this study, we investigated the role of miR-191 in HCC and studied its underlying mechanisms of a...

journal_title：Cell proliferation

authors： Tian F,Yu C,Wu M,Wu X,Wan L,Zhu X

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVES:Oestrogen is known to inhibit osteoclastogenesis, and numerous studies have identified it as an autophagic activator. To date, the role of oestrogen in the autophagy of osteoclast precursors (OCPs) during osteoclastogenesis remains unclear. This study aimed to determine the effect of autophagy regulated by t...

journal_title：Cell proliferation

authors： Cheng L,Zhu Y,Ke D,Xie D

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:Curcumin (capable of inhibiting angiogenic growth of human umbilical vein endothelial cells [HUVECs]), can be employed in vitro as a model of pathogenesis of corneal neovascularization (CRNV). The aim of this study was to explore regulatory mechanisms of microRNA (miR) levels after curcumin treatment. MATERI...

journal_title：Cell proliferation

authors： Bai Y,Wang W,Sun G,Zhang M,Dong J

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:The aim of the current study was to investigate whether nicotine treatment would induce the proliferation of isolated rat primary pancreatic acinar cells in culture by activating mitogen-activated protein kinase (MAPK) signalling and exocrine secretion. MATERIALS AND METHODS:A nicotine dose- and time-respon...

journal_title：Cell proliferation

authors： Chowdhury P,Bose C,Udupa KB

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVES:Liver regeneration is attenuated in old age and is substantially slower after 90% than after 70% partial hepatectomy (PH). We have previously demonstrated that the proliferative response to a primary mitogen is intact in aged mice, indicating that impaired liver regeneration is not due to loss of proliferati...

journal_title：Cell proliferation

authors： Columbano A,Simbula M,Pibiri M,Perra A,Deidda M,Locker J,Pisanu A,Uccheddu A,Ledda-Columbano GM

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVES:Small aromatic compounds like flavonoids can intercalate with DNA molecules bringing about conformational changes leading to reduced replication and transcription. Here, we have examined one dietary flavonoid, quercetin (found in many fruit and vegetables), for possible anti-cancer effects, on HeLa cells ori...

journal_title：Cell proliferation

authors： Bishayee K,Ghosh S,Mukherjee A,Sadhukhan R,Mondal J,Khuda-Bukhsh AR

更新日期：2013-04-01 00:00:00

abstract：:We have developed a mathematical model based on proliferation and infiltration of neoplastic cells that allows predictions to be made concerning the life expectancies following various extents of surgical resection of gliomas of all grades of malignancy. The key model parameters are the growth rate and the diffusion r...

journal_title：Cell proliferation

authors： Woodward DE,Cook J,Tracqui P,Cruywagen GC,Murray JD,Alvord EC Jr

更新日期：1996-06-01 00:00:00

abstract：OBJECTIVES:Mouse embryonic stem cell (mESC) culture contains various heterogeneous populations, which serve as excellent models to study gene regulation in early embryo development. The heterogeneity is typically defined by transcriptional activities, for example, the expression of Nanog or Rex1 mRNA. Our objectives we...

journal_title：Cell proliferation

authors： Hao J,Yang X,Zhang C,Zhang XT,Shi M,Wang SH,Mi L,Zhao YT,Cao H,Wang Y

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Five-year survival rate at early lung tumour was about 70%; however, its early diagnosis rate was still at a low level, so the enhancement of diagnosis level for early lung tumour is the key factor to increase the survival rate. Diagnosis and therapy of early lung tumour are still challenged. METHODS:The mag...

journal_title：Cell proliferation

authors： Yang Y,Huang Z,Pu X,Yin G,Wang L,Gao F

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVES:In this study, we have investigated whether secreted factors from embryonic stem cells (ESCs) could reprogramme keratinocytes and increase their potential to be directed into alternative cell lineages. MATERIALS AND METHODS:Contact and non-contact co-cultures of skin keratinocytes and murine ESCs were used ...

journal_title：Cell proliferation

authors： Grinnell KL,Bickenbach JR

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVES:Limbal stem cells (LSC) are self-renewing, highly proliferative cells in vitro, which express a set of specific markers and in vivo have the capacity to reconstruct the entire corneal epithelium in cases of ocular surface injury. Currently, LSC transplantation is a commonly used procedure in patients with ei...

journal_title：Cell proliferation

authors： Monteiro BG,Serafim RC,Melo GB,Silva MC,Lizier NF,Maranduba CM,Smith RL,Kerkis A,Cerruti H,Gomes JA,Kerkis I

更新日期：2009-10-01 00:00:00

abstract：:Proliferation and multidrug resistance status are key predictors of therapeutic outcome in acute myeloid leukaemia (AML). Anthracyclines such as daunorubicin (DNR) are typically used to treat AML and can induce drug resistance. The goal of the studies described here was to select a combination of fluorescent probes th...

journal_title：Cell proliferation

authors： Boutonnat J,Barbier M,Muirhead K,Mousseau M,Ronot X,Seigneurin D

更新日期：1999-08-01 00:00:00

abstract：:Programmed cell death (PCD)-apoptosis, autophagy and programmed necrosis-is any pathological form of cell death mediated by intracellular processes. Ototoxic drugs, ageing and noise exposure are some common pathogenic factors of sensorineural hearing loss (SNHL) that can induce the programmed death of auditory hair ce...

journal_title：Cell proliferation

authors： Wu J,Ye J,Kong W,Zhang S,Zheng Y

更新日期：2020-11-01 00:00:00

abstract：:The human promyelocytic leukaemia cell line, HL-60, was investigated with regard to proliferation and terminal differentiation following irradiation. The cells were X-irradiated and induced with 1.25% dimethyl sulfoxide (DMSO) towards the granulocytic lineage. Proliferation was measured via cell growth, clonogenicity ...

journal_title：Cell proliferation

authors： Sendler A,Kaffenberger W,Nuyken I,van Beuningen D

更新日期：1993-11-01 00:00:00

abstract：:WR-1065 (2-[(aminopropyl)amino]ethanethiol) reduces cytotoxic and mutagenic effects caused by exposure of cells to radiation and chemotherapeutic drugs, but the mechanisms involved are not fully known. We have observed an accumulation of cells in G2 in WR-1065 treated Chinese hamster ovary cells grown in alpha-minimal...

journal_title：Cell proliferation

authors： Murley JS,Grdina DJ,Meechan PJ

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:Accumulating data show that dysregulation of long noncoding RNAs (lncRNAs) acts a critical role in a variety of malignancies. Among these lncRNAs, small nucleolar RNA host genes (SNHGs) are associated with tumour growth and progression. But, the molecular mechanisms by which SNHG4 contributes to osteosarcoma ...

journal_title：Cell proliferation

authors： Xu R,Feng F,Yu X,Liu Z,Lao L

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVES:Hyperinsulinemia is a risk factor for pancreatic cancer, but the function of insulin in carcinogenesis is unclear, so this study aimed to elucidate the carcinogenic effects of insulin and the synergistic effect with the KRAS mutation in the early stage of pancreatic cancer. MATERIALS AND METHODS:A pair of i...

journal_title：Cell proliferation

authors： Wang G,Yin L,Peng Y,Gao Y,Gao H,Zhang J,Lv N,Miao Y,Lu Z

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:Generally, the secretory forms of FGF are known to regulate cell proliferation, differentiation and morphogenesis by binding to the extracellular domain of cell surface receptors. Intracellular FGFs (FGF11-14) are expressed principally in the nervous system. FGF13 is a microtubule-stabilizing protein that re...

journal_title：Cell proliferation

authors： Lu H,Shi X,Wu G,Zhu J,Song C,Zhang Q,Yang G

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVES:Vascular disorders are associated with phenotypical switching of vascular smooth muscle cells (VSMCs). We investigated the effect of bone morphogenetic protein (BMP)-2 in controlling VSMC phenotype and vascular disorder progression. Lysine (K)-specific demethylase 1A (KDM1A) has been identified to target BMP...

journal_title：Cell proliferation

authors： Zhang X,Huang T,Zhai H,Peng W,Zhou Y,Li Q,Yang H

更新日期：2020-01-01 00:00:00

abstract：:Breast cancer has seriously been threatening physical and mental health of women in the world, and its morbidity and mortality also show clearly upward trend in China over time. Through inquiry, we find that survival rate of patients with early-stage breast cancer is significantly higher than those with middle- and la...

journal_title：Cell proliferation

authors： He Z,Chen Z,Tan M,Elingarami S,Liu Y,Li T,Deng Y,He N,Li S,Fu J,Li W

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Worldwide, lung cancer accounts for the majority of cancer-related deaths. Aberrant expression of miRNAs has increasingly been reported to be associated with tumour progression. This study aimed to explore the role of miR-301b in regulating apoptosis in lung cancer. MATERIALS AND METHODS:Expression of miR-3...

journal_title：Cell proliferation

authors： Wu D,Chen B,Cui F,He X,Wang W,Wang M

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVES:Based on in vivo studies, low-intensity pulsed ultrasound (LIPUS) stimulation has been widely used in the clinic for advancing bone growth during healing of non-union alignment, fractures and other osseous defects. In this study, we have investigated osteogenic differentiation of adipose stem cells (ASCs) re...

journal_title：Cell proliferation

authors： Yue Y,Yang X,Wei X,Chen J,Fu N,Fu Y,Ba K,Li G,Yao Y,Liang C,Zhang J,Cai X,Wang M

更新日期：2013-06-01 00:00:00

abstract：:The microenvironmental changes in the bone marrow, spleen and liver during progression of the transplantable promyelocytic leukaemia in the Brown Norwegian rat (BNML) have been studied. We used flow cytometry to estimate cellular hypoxia and proliferation based on in vivo pulse-labelling with a mixture of 2-nitroimida...

journal_title：Cell proliferation

authors： Jensen PO,Mortensen BT,Hodgkiss RJ,Iversen PO,Christensen IJ,Helledie N,Larsen JK

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVES:We have evaluated the physiological roles of transforming growth factor-beta1 (TGF-beta1) on differentiation, migration, proliferation and anti-apoptosis characteristics of cultured spinal cord-derived neural progenitor cells. METHODS:We have used neural progenitor cells that had been isolated and cultured ...

journal_title：Cell proliferation

authors： Park SM,Jung JS,Jang MS,Kang KS,Kang SK

更新日期：2008-04-01 00:00:00