Triiodothyronine stimulates hepatocyte proliferation in two models of impaired liver regeneration.

abstract：:We have developed a mathematical model based on proliferation and infiltration of neoplastic cells that allows predictions to be made concerning the life expectancies following various extents of surgical resection of gliomas of all grades of malignancy. The key model parameters are the growth rate and the diffusion r...

journal_title：Cell proliferation

authors： Woodward DE,Cook J,Tracqui P,Cruywagen GC,Murray JD,Alvord EC Jr

更新日期：1996-06-01 00:00:00

abstract：:The relationship of cyclin-dependent kinase inhibitor 3 (CDKN3) with tumours has previously been presented in a number of publications. However, the molecular network and interpretation of CDKN3 through the cell cycle between non-malignancy associated hepatitis/cirrhosis and hepatocellular carcinoma (HCC) have remaine...

journal_title：Cell proliferation

authors： Wang L,Sun L,Huang J,Jiang M

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to obtain antitumour molecules targeting to activate PKM2 through adequate computational methods combined with biological activity experiments. METHODS:The structure-based virtual screening was utilized to screen effective activator targeting PKM2 from ZINC database. Molecular dyna...

journal_title：Cell proliferation

authors： Li Y,Bao M,Yang C,Chen J,Zhou S,Sun R,Wu C,Li X,Bao J

更新日期：2018-12-01 00:00:00

abstract：:Natural compounds derived from plant sources are well characterized as possessing a wide variety of remarkable anti-tumour properties, for example modulating programmed cell death, primarily referring to apoptosis, and autophagy. Distinct from apoptosis, autophagy (an evolutionarily conserved, multi-step lysosomal deg...

journal_title：Cell proliferation

authors： Zhang X,Chen LX,Ouyang L,Cheng Y,Liu B

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:To investigate the role of hierarchical micro/nanoscale topography of direct metal laser sintering (DMLS) titanium surfaces in osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs), as well as the possible underlying epigenetic mechanism. MATERIALS AND METHODS:Three groups of titanium spe...

journal_title：Cell proliferation

authors： Zheng G,Guan B,Hu P,Qi X,Wang P,Kong Y,Liu Z,Gao P,Li R,Zhang X,Wu X,Sui L

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:Mitophagy is considered to be a key mechanism in the pathogenesis of intestinal ischaemic reperfusion (IR) injury. NOD-like receptor X1 (NLRX1) is located in the mitochondria and is highly expressed in the intestine, and is known to modulate ROS production, mitochondrial damage, autophagy and apoptosis. Howe...

journal_title：Cell proliferation

authors： Li S,Zhou Y,Gu X,Zhang X,Jia Z

更新日期：2021-01-11 00:00:00

abstract：OBJECTIVE:Curcumin (capable of inhibiting angiogenic growth of human umbilical vein endothelial cells [HUVECs]), can be employed in vitro as a model of pathogenesis of corneal neovascularization (CRNV). The aim of this study was to explore regulatory mechanisms of microRNA (miR) levels after curcumin treatment. MATERI...

journal_title：Cell proliferation

authors： Bai Y,Wang W,Sun G,Zhang M,Dong J

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:The main purpose of current study was to explore the effects of tetrahedral DNA nanostructures (TDNs) on neuroectodermal (NE-4C) stem cells migration and unveil the potential mechanisms. MATERIALS AND METHODS:The successfully self-assembled TDNs were also determined by dynamic light scattering (DLS). A bidi...

journal_title：Cell proliferation

authors： Ma W,Xie X,Shao X,Zhang Y,Mao C,Zhan Y,Zhao D,Liu M,Li Q,Lin Y

更新日期：2018-12-01 00:00:00

abstract：:In situ presence of numerous DNA strand breaks is a typical feature of apoptotic cells. Selective DNA strand break induction by photolysis (SBIP) at sites that contain incorporated halogenated DNA precursors has recently been proposed as a method of analysing DNA replication. Detection of DNA strand breaks, thus, enab...

journal_title：Cell proliferation

authors： Li X,Darzynkiewicz Z

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVES:Induced pluripotent stem cell (iPSC)-derived cardiomyocytes are a promising source of cells for regenerative heart disease therapies, but progress towards their use has been limited by their low differentiation efficiency and high cellular heterogeneity. Previous studies have demonstrated expression of adren...

journal_title：Cell proliferation

authors： Li XL,Zeng D,Chen Y,Ding L,Li WJ,Wei T,Ou DB,Yan S,Wang B,Zheng QS

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:High mobility group protein2 (HMGA2) and epithelial-to-mesenchymal transition are both related to progress of bladder cancer, however, the relationship between HMGA2, E-cadherin and vimentin in bladder cancer is not yet known. Thus, this study has examined expression of HMGA2, E-cadherin and vimentin in blad...

journal_title：Cell proliferation

authors： Ding X,Wang Y,Ma X,Guo H,Yan X,Chi Q,Li J,Hou Y,Wang C

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:Restoring a functional beta-cell mass is a fundamental goal in treating diabetes. A complex signalling pathway network coordinates the regulation of beta-cell proliferation, although a role for ERK5 in this network has not been reported. This question was addressed in this study. MATERIALS AND METHODS:We st...

journal_title：Cell proliferation

authors： Chen C,Wu S,Lin X,Wu D,Fischbach S,Xiao X

更新日期：2018-06-01 00:00:00

abstract：:Recent epidemiological studies have demonstrated a correlation between regular aspirin (acetylsalicylic acid) use and decrease risk for the development of fatal colorectal cancer. An increase in the size of the cell proliferation compartment in colorectal crypts has been correlated with an increased risk for the devel...

journal_title：Cell proliferation

authors： Barnes CJ,Lee M,Hardman WE,Cameron IL

更新日期：1995-02-01 00:00:00

abstract：:A number of techniques, including autoradiography after in vivo administration of tritiated thymidine ([3H]dT), immunohistochemistry after in vivo administration of bromodeoxyuridine (BrdUrd), and flow cytometry (FCM) with and without BrdUrd detection were compared in the epithelium of ventral mouse tongue. Investigat...

journal_title：Cell proliferation

authors： Dörr W,Arui J,Beisker W,Schultz-Hector S

更新日期：1994-06-01 00:00:00

abstract：:Electromagnetic ultra-wideband pulses (UWB) or nanopulses, are generated by a wide range of electronic devices used in communications and radar technology. However, the specific effects of nanopulse exposure on cell growth and function have not been extensively investigated. Here, studies have been conducted to determ...

journal_title：Cell proliferation

authors： Sylvester PW,Shah SJ,Haynie DT,Briski KP

更新日期：2005-06-01 00:00:00

abstract：:Cytokines and growth factors that take part in the regulation of haematopoietic cell development activate many signalling pathways in target cells. The STAT5 (signal transducers and activators of transcription) proteins are members of a family of signal transducers and activators of transcription that can be activated...

journal_title：Cell proliferation

authors： Baśkiewicz-Masiuk M,Paczkowski M,Machaliński B

更新日期：2004-06-01 00:00:00

abstract：:This study examines epithelial cell streaming and turnover in normal rat bulbar conjunctiva. Twenty seven male adult random-bred Hebrew rats weighing between 250-300 g, were injected i.p. with [3H]-thymidine. Three rats were killed at various times, thereafter from 1 h to 28 days. The enucleated eyes were fixed in for...

journal_title：Cell proliferation

authors： Zajicek G,Perry A,Pe'er J

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVES:Skin-derived precursors are recognized to be a potentially autologous and accessible source of neural precursor cells for drug screening or cell-based treatments, in many neurological disorders. Thus, it is necessary to investigate appropriate methods for cryopreservation of such human skin-derived precursor...

journal_title：Cell proliferation

authors： Bakhtiari M,Mansouri K,Sadeghi Y,Mostafaie A

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:It is not known whether or not epithelial progenitors of the pyloric antrum are involved in gastric carcinogenesis. Normally, these progenitors give rise to two main cell lineages: pit and gland mucous cells. This study was designed to examine the changes that occur in pyloric antral mucous cell lineages and ...

journal_title：Cell proliferation

authors： Karam SM,Tomasetto C,Rio MC

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVES:Mouse embryonic stem cell (mESC) culture contains various heterogeneous populations, which serve as excellent models to study gene regulation in early embryo development. The heterogeneity is typically defined by transcriptional activities, for example, the expression of Nanog or Rex1 mRNA. Our objectives we...

journal_title：Cell proliferation

authors： Hao J,Yang X,Zhang C,Zhang XT,Shi M,Wang SH,Mi L,Zhao YT,Cao H,Wang Y

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:Based on in vivo studies, low-intensity pulsed ultrasound (LIPUS) stimulation has been widely used in the clinic for advancing bone growth during healing of non-union alignment, fractures and other osseous defects. In this study, we have investigated osteogenic differentiation of adipose stem cells (ASCs) re...

journal_title：Cell proliferation

authors： Yue Y,Yang X,Wei X,Chen J,Fu N,Fu Y,Ba K,Li G,Yao Y,Liang C,Zhang J,Cai X,Wang M

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:Thyroid carcinoma (TC) represents a malignant neoplasm affecting the thyroid. Current treatment strategies include the removal of part of the thyroid; however, this approach is associated with a significant risk of developing hypothyroidism. In order to adequately understand the expression profiles of TNRC6C...

journal_title：Cell proliferation

authors： Yang LX,Wu J,Guo ML,Zhang Y,Ma SG

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:Often, non-small cell lung cancers (NSCLC) respond only poorly to the tyrosine kinase inhibitor (TKI) gefitinib, which targets the epidermal growth factor receptor (EGFR), these poor responders EGFRs lacking activating mutations. In this study, we have attempted to improve TKI response of NSCLC cell lines (A...

journal_title：Cell proliferation

authors： Postiglione I,Chiaviello A,Aloj SM,Palumbo G

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVES:The transfer of melanosomes from melanocytes to neighbouring keratinocytes is critical to protect the skin from the deleterious effects of ultraviolet A (UVA) and ultraviolet B (UVB) irradiation; however, the initial factor(s) that stimulates melanosome transfer remains unclear. In this study, we investigate...

journal_title：Cell proliferation

authors： Hu QM,Yi WJ,Su MY,Jiang S,Xu SZ,Lei TC

更新日期：2017-12-01 00:00:00

abstract：INTRODUCTION/OBJECTIVES:The serine/threonine kinase homeodomain-interacting protein kinase 2 (HIPK2) is a co-regulator of an increasing number of transcription factors and cofactors involved in DNA damage response and development. We and others have cloned HIPK2 as an interactor of the p53 oncosuppressor, and have stud...

journal_title：Cell proliferation

authors： Iacovelli S,Ciuffini L,Lazzari C,Bracaglia G,Rinaldo C,Prodosmo A,Bartolazzi A,Sacchi A,Soddu S

更新日期：2009-06-01 00:00:00

abstract：:The microenvironmental changes in the bone marrow, spleen and liver during progression of the transplantable promyelocytic leukaemia in the Brown Norwegian rat (BNML) have been studied. We used flow cytometry to estimate cellular hypoxia and proliferation based on in vivo pulse-labelling with a mixture of 2-nitroimida...

journal_title：Cell proliferation

authors： Jensen PO,Mortensen BT,Hodgkiss RJ,Iversen PO,Christensen IJ,Helledie N,Larsen JK

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVES:The aim of the current study was to investigate whether nicotine treatment would induce the proliferation of isolated rat primary pancreatic acinar cells in culture by activating mitogen-activated protein kinase (MAPK) signalling and exocrine secretion. MATERIALS AND METHODS:A nicotine dose- and time-respon...

journal_title：Cell proliferation

authors： Chowdhury P,Bose C,Udupa KB

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVES:This study is to explore the role of Notch signalling during the regeneration of rat tracheal epithelium after injury induced by 5-fluorouracil (5-FU). MATERIALS AND METHODS:We developed an ex vivo model of rat tracheal epithelial regeneration using 5-FU to induce injury. Expression levels of members of the...

journal_title：Cell proliferation

authors： Ma XB,Jia XS,Liu YL,Wang LL,Sun SL,Song N,Wang EH,Li F

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:Accumulating studies have investigated the PM2.5-induced pulmonary toxicity, while gaps still remain in understanding its toxic mechanism. Due to its high specific surface area and adsorption capacity similar to nanoparticles, PM2.5 acts as a significant carrier of metals in air and then leads to altered tox...

journal_title：Cell proliferation

authors： He W,Peng H,Ma J,Wang Q,Li A,Zhang J,Kong H,Li Q,Sun Y,Zhu Y

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the role of insulin-like growth factor-1 (IGF-1) and crosstalk between endothelial cells (ECs) and adipose-derived stem cells (ASCs) in the process of angiogenesis. METHODS:A three-dimensional collagen gel used to culture mouse ASCs and mouse ECs in vitro was establi...

journal_title：Cell proliferation

authors： Lin S,Zhang Q,Shao X,Zhang T,Xue C,Shi S,Zhao D,Lin Y

更新日期：2017-12-01 00:00:00