Hypoxia-induced microRNA-301b regulates apoptosis by targeting Bim in lung cancer.

abstract：:Epstein-Barr virus (EBV) infection in vitro causes transformation of B cells and generates B lymphoblastoid cell lines (LCLs). These LCLs have been widely used for the diagnostic of several genetic metabolic disorders. However, up to now, efficiency of LCL generation has been based on misleading subjective analysis. I...

journal_title：Cell proliferation

authors： Mello AS,Burin MG,Michellin K,Viapiana M,Giugliani R,Coelho JC,Bauer ME

更新日期：2006-02-01 00:00:00

abstract：:Stem cells are regenerating medicine. Advances in stem cell biology, and bone marrow-derived mesenchymal stem cells in particular, are demonstrating that many clinical options once thought to be science fiction may be attainable as fact. The extra- and intra-cellular signalling used by stem cells as they differentiate...

journal_title：Cell proliferation

authors： Otto WR,Rao J

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVES:This study investigated effects of reduced serum condition and vascular endothelial growth factor (VEGF) on angiogenic potential of adipose stromal cells (ASCs) in vitro. MATERIALS AND METHODS:Adipose stromal cells were cultured in three different types of medium: (i) F12/DMEM (FD) supplemented with 10% FBS...

journal_title：Cell proliferation

authors： Chua KH,Raduan F,Wan Safwani WK,Manzor NF,Pingguan-Murphy B,Sathapan S

更新日期：2013-06-01 00:00:00

abstract：:In vitro cultured Ehrlich ascites tumour (EAT) cells were used because of the ease of their manipulation under different levels of hypoxia. They were used to clarify further the complex mechanism of oxygen-dependent cell proliferation. On reducing the oxygen concentration from 20% to lower levels (1-7%) an increase in...

journal_title：Cell proliferation

authors： Löffler M

更新日期：1992-05-01 00:00:00

abstract：:Programmed cell death (PCD)-apoptosis, autophagy and programmed necrosis-is any pathological form of cell death mediated by intracellular processes. Ototoxic drugs, ageing and noise exposure are some common pathogenic factors of sensorineural hearing loss (SNHL) that can induce the programmed death of auditory hair ce...

journal_title：Cell proliferation

authors： Wu J,Ye J,Kong W,Zhang S,Zheng Y

更新日期：2020-11-01 00:00:00

abstract：:The essential oil extracted from clove (Syzygium aromaticum) is used as a topical application to relieve pain and promote healing in herbal medicine and also finds use in the fragrance and flavouring industries. Clove oil has two major components, eugenol and beta-caryophyllene, which constitute 78% and 13% of the oil...

journal_title：Cell proliferation

authors： Prashar A,Locke IC,Evans CS

更新日期：2006-08-01 00:00:00

abstract：:Breast cancer has seriously been threatening physical and mental health of women in the world, and its morbidity and mortality also show clearly upward trend in China over time. Through inquiry, we find that survival rate of patients with early-stage breast cancer is significantly higher than those with middle- and la...

journal_title：Cell proliferation

authors： He Z,Chen Z,Tan M,Elingarami S,Liu Y,Li T,Deng Y,He N,Li S,Fu J,Li W

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:This study aims to explore the roles of N-myc and caspase-8 in TRAIL-resistant IMR-32 cells which exhibit MYCN oncogene amplification and lack caspase-8 expression. MATERIALS AND METHODS:We established N-myc-downregulated IMR-32 cells using shRNA lentiviral particles targeting N-myc and examined the effect ...

journal_title：Cell proliferation

authors： Lee MW,Kim DS,Kim HR,Park HJ,Lee JW,Sung KW,Koo HH,Yoo KH

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVES:Oestrogen receptor (ER) is a common nucleus receptor that is essential for the regulation of cell growth, proliferation and differentiation. This study was to examine whether ERα can affect the proliferation and odonto/osteogenic differentiation of stem cells from apical papilla (SCAPs). MATERIALS AND METHO...

journal_title：Cell proliferation

authors： Wang Y,Lu Y,Li Z,Zhou Y,Gu Y,Pang X,Wu J,Gobin R,Yu J

更新日期：2018-12-01 00:00:00

abstract：:Studies to examine the percentages of proliferating plasma cells (PPC) in the Harderian gland (HG) were carried out in chicks between 5 and 12 weeks of age. Two methods, 5-bromo-2'-deoxyuridine (BrdUrd) incorporation into DNA and flow cytometric analysis of propidium iodide (PI) stained cells, were employed in control...

journal_title：Cell proliferation

authors： Savage ML,Oláh I,Scott TR

更新日期：1992-07-01 00:00:00

abstract：:Neural stem cells (NSCs) are early precursors of neuronal and glial cells. NSCs are capable of generating identical progeny through virtually unlimited numbers of cell divisions (cell proliferation), producing daughter cells committed to differentiation. Nuclear factor kappa B (NF-kappaB) is an inducible, ubiquitous t...

journal_title：Cell proliferation

authors： Piotrowska MJ,Widera D,Kaltschmidt B,an der Heiden U,Kaltschmidt C

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVES:The bone tissue engineering primarily focuses on three-dimensional co-culture systems, which physical and biological properties resemble the cell matrix of actual tissues. The complex dialogue between bone-forming and endothelial cells (ECs) in a tissue-engineered construct will directly regulate angiogenesi...

journal_title：Cell proliferation

authors： Li L,Li J,Zou Q,Zuo Y,Cai B,Li Y

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVES:Beryllium salts (here, beryllium sulphate) can produce a cytostatic effect in some cell types. The basis for this effect may include increased expression of proliferation inhibitors, reduced expression of proliferation promoters, or both. This study sought to determine the role of p53, the tumour-suppressing...

journal_title：Cell proliferation

authors： Gorjala P,Cairncross JG,Gary RK

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:SAV1 is a human homologue of Salvador that contains two protein-protein interaction modules known as WW domains and acts as a scaffolding protein. SAV1 participates in the development of diverse types of cancer. We aimed to investigate the role of SAV1 in human colorectal cancer. MATERIALS AND METHODS:Human...

journal_title：Cell proliferation

authors： Jiang J,Chang W,Fu Y,Gao Y,Zhao C,Zhang X,Zhang S

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:Autophagy, a highly conserved lysosomal degradation process in eukaryotic cells, can digest long-lived proteins and damaged organelles through vesicular trafficking pathways. Nowadays, mechanisms of autophagy have been gradually elucidated and thus the discovery of small-molecule drugs targeting autophagy ha...

journal_title：Cell proliferation

authors： Deng Y,Zhu L,Cai H,Wang G,Liu B

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVES:Increasing evidences suggest that inducing mesenchymal stem cells to differentiate into osteoblasts has been as an especially important component in the prevention and therapy for degenerative bone disease. Here, we identify a novel lncRNA, linc02349, which increases significantly during osteogenic different...

journal_title：Cell proliferation

authors： Cao L,Liu W,Zhong Y,Zhang Y,Gao D,He T,Liu Y,Zou Z,Mo Y,Peng S,Shuai C

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:Secondary bacterial pneumonia is common following influenza infection. However, it remains unclear about the underlying molecular mechanisms. MATERIALS AND METHODS:We established a mouse model of post-influenza S aureus pneumonia using conditional Shp2 knockout mice (LysMCre/+ :Shp2flox/flox ). The survival...

journal_title：Cell proliferation

authors： Ouyang W,Liu C,Pan Y,Han Y,Yang L,Xia J,Xu F

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Translational research using adult stem cells derived from various tissues has been highlighted in cell-based therapy. However, there are many limitations to using conventional culture systems of adult stem cells for clinically applicability, including limited combinations of cytokines and use of nutrients d...

journal_title：Cell proliferation

authors： Shin KS,Lee HJ,Jung J,Cha DH,Kim GJ

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:To evaluate the rapid repair potential of adipose-derived stem cells (ADSCs) co-overexpressing VEGF and GDNF on bilateral cavernous nerve injury (BCNI) in rat models. Progressive fibrosis of the penis that occurs shortly after BCNI is a key cause of clinical treatment difficulty of erectile dysfunction (ED)....

journal_title：Cell proliferation

authors： Yang W,Chen Z,Ma X,Ouyang X,Fang J,Wei H

更新日期：2020-02-01 00:00:00

abstract：:Natural compounds derived from plant sources are well characterized as possessing a wide variety of remarkable anti-tumour properties, for example modulating programmed cell death, primarily referring to apoptosis, and autophagy. Distinct from apoptosis, autophagy (an evolutionarily conserved, multi-step lysosomal deg...

journal_title：Cell proliferation

authors： Zhang X,Chen LX,Ouyang L,Cheng Y,Liu B

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the role of insulin-like growth factor-1 (IGF-1) and crosstalk between endothelial cells (ECs) and adipose-derived stem cells (ASCs) in the process of angiogenesis. METHODS:A three-dimensional collagen gel used to culture mouse ASCs and mouse ECs in vitro was establi...

journal_title：Cell proliferation

authors： Lin S,Zhang Q,Shao X,Zhang T,Xue C,Shi S,Zhao D,Lin Y

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Erythropoietin has been shown to have a protective effect in certain models of ischaemia-reperfusion, and in some cases the protection has been correlated with activation of signalling pathways known to play a role in cell survival and proliferation. We have studied whether erythropoietin would overcome direc...

journal_title：Cell proliferation

authors： Andreucci M,Fuiano G,Presta P,Lucisano G,Leone F,Fuiano L,Bisesti V,Esposito P,Russo D,Memoli B,Faga T,Michael A

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:Creation of functional, durable vasculature remains an important goal within the field of regenerative medicine. Engineered biological vasculature has the potential to restore or improve human tissue function. We hypothesized that the pleotropic effects of insulin-like growth factor 1 (IGF1) would enhance th...

journal_title：Cell proliferation

authors： Friedrich CC,Lin Y,Krannich A,Wu Y,Vacanti JP,Neville CM

更新日期：2018-02-01 00:00:00

abstract：:An ELISA was developed and optimized to measure cell proliferation using a monoclonal antibody to bromodeoxyuridine (BrdUrd). Incorporation of BrdUrd into myoblast monolayers, measured as the optical density at 492 nm, increased in response to fetal calf serum, IGF-I and EGF, the ELISA data correlated closely with dat...

journal_title：Cell proliferation

authors： Perros P,Weightman DR

更新日期：1991-09-01 00:00:00

abstract：:Advances in transcriptome sequencing have revealed that the genome fraction largely encodes for thousands of non-coding RNAs. Long non-coding RNAs (lncRNAs), which are a class of non-protein-coding RNAs longer than approximately 200 nucleotides in length, are emerging as key epigenetic regulators of gene expression re...

journal_title：Cell proliferation

authors： Tang L,Liang Y,Xie H,Yang X,Zheng G

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Somatic stem cells can be obtained from a variety of adult human tissues. However, it was not clear whether human parathyroid glands, which secrete parathyroid hormones and are essential in maintaining homeostasis levels of calcium ions in the circulation, contained stem cells. We aimed to investigate the po...

journal_title：Cell proliferation

authors： Shih YR,Kuo TK,Yang AH,Lee OK,Lee CH

更新日期：2009-08-01 00:00:00

abstract：:On 31 May 2010, 14 072 567 bone marrow/apheresis donors registered in 44 countries and 426 501 cord blood units banked in 26 countries for public use were available to treat candidates to haemopoietic stem cell transplant lacking a family related compatible donor. Despite these impressive numbers, additional efforts a...

journal_title：Cell proliferation

authors： Rebulla P,Lecchi L

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVES:In order to provide a more comprehensive understanding of the effects of SARS-CoV-2 on oral health and possible saliva transmission, we performed RNA-seq profiles analysis from public databases and also a questionnaire survey on oral-related symptoms of COVID-19 patients. MATERIALS AND METHODS:To analyse AC...

journal_title：Cell proliferation

authors： Chen L,Zhao J,Peng J,Li X,Deng X,Geng Z,Shen Z,Guo F,Zhang Q,Jin Y,Wang L,Wang S

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:The role of stem cells in regenerative medicine is evolving rapidly. Here, we describe the application, for kidney regeneration, of a novel non-genetically modified stem cell, derived from human amniotic fluid. We show that these pluripotent cells can develop and differentiate into de novo kidney structures ...

journal_title：Cell proliferation

authors： Perin L,Giuliani S,Jin D,Sedrakyan S,Carraro G,Habibian R,Warburton D,Atala A,De Filippo RE

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVES:Osteopetrosis is a rare inherited skeletal disease characterized by increased bone mineral density due to the loss of osteoclast function or differentiation potential. MATERIALS AND METHODS:The study involved a Chinese patient with osteopetrosis (the proband) and her immediate family members and 180 control...

journal_title：Cell proliferation

authors： Yuan Y,Yang L,Liu T,Zhang H,Lu Q

更新日期：2019-11-01 00:00:00