Circulating microRNA signature of steroid-induced osteonecrosis of the femoral head.

abstract：OBJECTIVES:MicroRNAs are powerful regulators in hepatocellular carcinoma (HCC) tumorigenesis. MicoRNA-191 (miR-191) has been reported to play an important role in HCC, However, the regulatory mechanism is still unclear. In this study, we investigated the role of miR-191 in HCC and studied its underlying mechanisms of a...

journal_title：Cell proliferation

authors： Tian F,Yu C,Wu M,Wu X,Wan L,Zhu X

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVES:Thyroid carcinoma (TC) represents a malignant neoplasm affecting the thyroid. Current treatment strategies include the removal of part of the thyroid; however, this approach is associated with a significant risk of developing hypothyroidism. In order to adequately understand the expression profiles of TNRC6C...

journal_title：Cell proliferation

authors： Yang LX,Wu J,Guo ML,Zhang Y,Ma SG

更新日期：2019-05-01 00:00:00

abstract：:Stem cell research is now a very broad field encompassing cells derived from all stages of life from the embryonic stem cells of the early blastocyst through to the adult stem cells of many tissues of the body. Adult stem cells from a variety of tissues are proving to be pluripotent and can differentiate into cell typ...

journal_title：Cell proliferation

authors： Mackay-Sim A,Silburn P

更新日期：2008-02-01 00:00:00

abstract：:Cell proliferation was investigated in human tumour xenografts using bromodeoxyuridine (BrdUrd) labelling, evaluated either by flow cytometry or in tissue sections, and also using the proliferation marker Ki-67. BrdUrd labelling was found to increase when cryostat tumour sections were digested with an enzymic solution...

journal_title：Cell proliferation

authors： Parkins CS,Bush C,Price P,Steel GG

更新日期：1991-03-01 00:00:00

abstract：OBJECTIVES:Dental follicle cells (DFCs) provide the origin of periodontal tissues, and Runx2 is essential for bone formation and tooth development. In this study, pluripotency of DFCs was evaluated and effects of Runx2 on them were investigated. MATERIALS AND METHODS:The DFCs were induced to differentiate towards oste...

journal_title：Cell proliferation

authors： Pan K,Sun Q,Zhang J,Ge S,Li S,Zhao Y,Yang P

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVES:Enterochromaffin (EC) cells have been associated with functional gastrointestinal disorders such as IBS. Recently, we found that glial cell-derived neurotrophic factor (GDNF)-rearranged during transfection (RET) localized in EC cells in human colonic epithelia. Here, we examine the role of GDNF-RET in the pa...

journal_title：Cell proliferation

authors： Lin L,Feng B,Zhou R,Liu Y,Li L,Wang K,Yu Y,Liu C,Long X,Gu X,Li B,Wang X,Yang X,Cong Y,Zuo X,Li Y

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:Osteopetrosis is a rare inherited skeletal disease characterized by increased bone mineral density due to the loss of osteoclast function or differentiation potential. MATERIALS AND METHODS:The study involved a Chinese patient with osteopetrosis (the proband) and her immediate family members and 180 control...

journal_title：Cell proliferation

authors： Yuan Y,Yang L,Liu T,Zhang H,Lu Q

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:Intracellular reactive oxygen species (ROS) induced by receptor activator of NF-kB ligand (RANKL) has been proven to be a critical factor in the development of osteoclasts. This study aimed to prove that schisandrin A (Sch), a novel anti-oxidant compound, is able to suppress osteoclastogenesis and prevent bo...

journal_title：Cell proliferation

authors： Ni S,Qian Z,Yuan Y,Li D,Zhong Z,Ghorbani F,Zhang X,Zhang F,Zhang Z,Liu Z,Yu B

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:Erythropoietin has been shown to have a protective effect in certain models of ischaemia-reperfusion, and in some cases the protection has been correlated with activation of signalling pathways known to play a role in cell survival and proliferation. We have studied whether erythropoietin would overcome direc...

journal_title：Cell proliferation

authors： Andreucci M,Fuiano G,Presta P,Lucisano G,Leone F,Fuiano L,Bisesti V,Esposito P,Russo D,Memoli B,Faga T,Michael A

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:To evaluate the effects of rRNA synthesis inhibition on cell cycle progression and cell population growth according to the RB and p53 status. MATERIAL AND METHODS:RB- and p53-proficient U2OS cells and the RB- and p53-deficient SAOS-2 cells were used, rRNA transcription hindered by actinomycin D, and cell cy...

journal_title：Cell proliferation

authors： Montanaro L,Mazzini G,Barbieri S,Vici M,Nardi-Pantoli A,Govoni M,Donati G,Treré D,Derenzini M

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVES:In peripheral neuropathy, the underlying mechanisms of nerve and muscle degeneration include chronic inflammation and oxidative stress in fibrotic tissues. (-)-Epigallocatechin gallate (EGCG) is a major, active component in green tea and may scavenge free radical oxygen and attenuate inflammation. Conservati...

journal_title：Cell proliferation

authors： Qian Y,Yao Z,Wang X,Cheng Y,Fang Z,Yuan WE,Fan C,Ouyang Y

更新日期：2020-01-01 00:00:00

abstract：:Studies to examine the percentages of proliferating plasma cells (PPC) in the Harderian gland (HG) were carried out in chicks between 5 and 12 weeks of age. Two methods, 5-bromo-2'-deoxyuridine (BrdUrd) incorporation into DNA and flow cytometric analysis of propidium iodide (PI) stained cells, were employed in control...

journal_title：Cell proliferation

authors： Savage ML,Oláh I,Scott TR

更新日期：1992-07-01 00:00:00

abstract：:WR-1065 (2-[(aminopropyl)amino]ethanethiol) reduces cytotoxic and mutagenic effects caused by exposure of cells to radiation and chemotherapeutic drugs, but the mechanisms involved are not fully known. We have observed an accumulation of cells in G2 in WR-1065 treated Chinese hamster ovary cells grown in alpha-minimal...

journal_title：Cell proliferation

authors： Murley JS,Grdina DJ,Meechan PJ

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVES:This study was designed to investigate the role of circ_0078767/miR-330-3p/RASSF1A in non-small-cell lung cancer (NSCLC). Bioinformatic analysis was performed to screen for the differentially expressed genes in NSCLC tissues from adjacent lung tissues. MATERIALS AND METHODS:qRT-PCR was used to detect the RN...

journal_title：Cell proliferation

authors： Chen T,Yang Z,Liu C,Wang L,Yang J,Chen L,Li W

更新日期：2019-03-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a primary liver malignancy with a high global prevalence and a dismal prognosis. Studies are urgently needed to examine the molecular pathogenesis and biological characteristics of HCC. Chromatin remodelling, an integral component of the DNA damage response, protects against DNA damag...

journal_title：Cell proliferation

authors： Hu B,Lin JZ,Yang XB,Sang XT

更新日期：2020-04-01 00:00:00

abstract：:Autophagy follows a lysosomal degradation pathway in which a cell digests its own components. It is highly regulated by a limited number of autophagy-related genes (Atg) and the proteins they encode, that are crucial for cells to undergo the process via modulating autophagsome formation. Recently, accumulating evidenc...

journal_title：Cell proliferation

authors： Chen Y,Liu XR,Yin YQ,Lee CJ,Wang FT,Liu HQ,Wu XT,Liu J

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:To assess the expression, prognostic value, and functionality of T-lymphokine-activated killer (T-LAK) cell-originated protein kinase (TOPK) in chordoma pathogenesis. MATERIALS AND METHODS:TOPK expression in chordoma was assessed via immunohistochemical staining of a tissue microarray (TMA) and correlated w...

journal_title：Cell proliferation

authors： Thanindratarn P,Dean DC,Nelson SD,Hornicek FJ,Duan Z

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:MicroRNAs (miRNAs) are negative regulators of gene expression that play important roles in cell processes such as proliferation, development and differentiation. Recently, it has been reported that miRNAs are related to development of carcinogenesis. The aim of this study was to identify miRNAs associated wit...

journal_title：Cell proliferation

authors： Lee JE,Hong EJ,Nam HY,Kim JW,Han BG,Jeon JP

更新日期：2011-02-01 00:00:00

abstract：:The epithelium of the oral cavity and small intestine of the gastrointestinal tract have a high rate of cell renewal and as such, are sensitive to cytotoxic therapies that kill rapidly dividing cells. Mucositis is a complication of cancer therapy where impairment of the regenerative capacity of the epithelium leads to...

journal_title：Cell proliferation

authors： Farrell CL,Rex KL,Chen JN,Bready JV,DiPalma CR,Kaufman SA,Rattan A,Scully S,Lacey DL

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVES:Panax ginseng, a well-known traditional Chinese medicine with multiple pharmacological activities, plays a crucial role in modulating mood disorders. Several recent studies have identified an underlying role of Panax ginseng in the prevention and treatment of depression. However, the cellular and molecular m...

journal_title：Cell proliferation

authors： Jin Y,Cui R,Zhao L,Fan J,Li B

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:Recent data show that Imatinib mesylate (IM) also affects haematopoietic stem cells (HSC), T lymphocytes and dendritic cells that do not harbour constitutively active tyrosine kinases. MATERIALS AND METHODS:We evaluated possible effects of IM on human bone marrow-derived mesenchymal stem cells (MSC) in vitr...

journal_title：Cell proliferation

authors： Fierro F,Illmer T,Jing D,Schleyer E,Ehninger G,Boxberger S,Bornhäuser M

更新日期：2007-06-01 00:00:00

abstract：:The expression of the 170-kDa (alpha) and the 180-kDa (beta) isoforms of DNA topoisomerase II (topo II) was investigated with two specific monoclonal antibodies (MoAbs) in human peripheral blood lymphocytes (PBL), before and after phytohaemoagglutinin (PHA) stimulation. Binding of each MoAb was detected by indirect im...

journal_title：Cell proliferation

authors： Prosperi E,Negri C,Marchese G,Ricotti GC

更新日期：1994-05-01 00:00:00

abstract：:Proliferation and multidrug resistance status are key predictors of therapeutic outcome in acute myeloid leukaemia (AML). Anthracyclines such as daunorubicin (DNR) are typically used to treat AML and can induce drug resistance. The goal of the studies described here was to select a combination of fluorescent probes th...

journal_title：Cell proliferation

authors： Boutonnat J,Barbier M,Muirhead K,Mousseau M,Ronot X,Seigneurin D

更新日期：1999-08-01 00:00:00

abstract：:The relationship of cyclin-dependent kinase inhibitor 3 (CDKN3) with tumours has previously been presented in a number of publications. However, the molecular network and interpretation of CDKN3 through the cell cycle between non-malignancy associated hepatitis/cirrhosis and hepatocellular carcinoma (HCC) have remaine...

journal_title：Cell proliferation

authors： Wang L,Sun L,Huang J,Jiang M

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:In order to provide a more comprehensive understanding of the effects of SARS-CoV-2 on oral health and possible saliva transmission, we performed RNA-seq profiles analysis from public databases and also a questionnaire survey on oral-related symptoms of COVID-19 patients. MATERIALS AND METHODS:To analyse AC...

journal_title：Cell proliferation

authors： Chen L,Zhao J,Peng J,Li X,Deng X,Geng Z,Shen Z,Guo F,Zhang Q,Jin Y,Wang L,Wang S

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:The main purpose of current study was to explore the effects of tetrahedral DNA nanostructures (TDNs) on neuroectodermal (NE-4C) stem cells migration and unveil the potential mechanisms. MATERIALS AND METHODS:The successfully self-assembled TDNs were also determined by dynamic light scattering (DLS). A bidi...

journal_title：Cell proliferation

authors： Ma W,Xie X,Shao X,Zhang Y,Mao C,Zhan Y,Zhao D,Liu M,Li Q,Lin Y

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Low levels of adiponectin (APN), a biomarker of diabetes mellitus, have been implicated in the poor outcome of intracerebral haemorrhage (ICH). Herein, we aimed to demonstrate the neuroprotective effects of a blood-brain barrier-permeable APN peptide (APNp) on ICH injury in diabetic mice and explore the under...

journal_title：Cell proliferation

authors： Wu X,Luo J,Liu H,Cui W,Guo W,Zhao L,Guo H,Bai H,Guo K,Feng D,Qu Y

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:Creation of functional, durable vasculature remains an important goal within the field of regenerative medicine. Engineered biological vasculature has the potential to restore or improve human tissue function. We hypothesized that the pleotropic effects of insulin-like growth factor 1 (IGF1) would enhance th...

journal_title：Cell proliferation

authors： Friedrich CC,Lin Y,Krannich A,Wu Y,Vacanti JP,Neville CM

更新日期：2018-02-01 00:00:00

abstract：:RAIDD (RIP-associated ICH-1 homologous protein with a death domain) is an adaptor molecule that mediates the action of cysteine proteases involved in apoptosis. To study the possibility of a novel system of cell ablation mediated by RAIDD, a preadipocyte cell line (3T3L1) was stably transfected with a plasmid containi...

journal_title：Cell proliferation

authors： Felmer R,Horvat S,Clinton M,Clark AJ

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVES:To understand if there exists a functional interaction between arsenic trioxide and paclitaxel in vitro. MATERIALS AND METHODS:HeLa and HCT116 (rho53(+/+) and rho53(-/-)) cells were treated with As2O3 and/or paclitaxel for various times. Treated cells were collected for analyses using a combination of flow ...

journal_title：Cell proliferation

authors： Duan Q,Komissarova E,Dai W

更新日期：2009-06-01 00:00:00