Thrombotic microangiopathy in living-donor liver transplantation.

abstract：:The presence of major histocompatibility complex (MHC)-encoded antigens (RT1) on endothelium of rat kidneys was investigated using hyperimmune allogeneic rat sera (HIS) in an indirect immunofluorescence technique with kidney sections. Endothelial antigens detected with anti-MHC sera segregated in an F2 generation with...

journal_title：Transplantation

authors： Paul LC,Paradysz JM,Milford EL,Kunz HW,Carpenter CB

更新日期：1982-09-01 00:00:00

abstract：:Natural killer (NK) lymphocytes are powerful effector cells of the peripheral immune system. NK cell functions are controlled by the expression of a variety of cell surface receptors with either inhibitory or activating roles. The genetic and functional diversity of this repertoire of receptors and the role of human l...

journal_title：Transplantation

authors： Young NT

更新日期：2004-07-15 00:00:00

abstract：BACKGROUND AND METHODS:To investigate the frequency of apoptosis and the expression of Fas/Fas ligand (FasL) in liver allografts, we examined 97 biopsy specimens from 62 patients after orthotopic liver transplantation. The results of the biopsies were as follows: acute allograft rejection (n=32); hepatitis C virus (HCV...

journal_title：Transplantation

authors： Tannapfel A,Kohlhaw K,Ebelt J,Hauss J,Liebert U,Berr F,Wittekind C

更新日期：1999-04-15 00:00:00

abstract：:Because of the inherent difficulties in allele assignment with HLA-DR serological typing, in 1993 our organ procurement organization-based HLA laboratory replaced serology with the molecular method of polymerase chain reaction using sequence-specific primer mixes (PCR-SSP) to type for DR and DQ at a resolution level e...

journal_title：Transplantation

authors： Bryan CF,Harrell KM,Nelson PW,Pierce GE,Ross G,Shield CF 3rd,Warady BA,Aeder MI,Helling TS,Landreneau MD,Luger AM

更新日期：1996-12-27 00:00:00

abstract：BACKGROUND:Pancreatic islets are avascular immediately after transplantation and depend on revascularization. Recently, the authors found decreased vascular density in mouse islets 1 month after implantation into nondiabetic recipients. This study investigated possible differences in revascularization between islets im...

journal_title：Transplantation

authors： Mattsson G,Jansson L,Nordin A,Carlsson PO

更新日期：2003-03-15 00:00:00

abstract：:Several approaches have been attempted to manage renal allograft dysfunction in cyclosporine-prednisone (CsA-Pred)-treated patients. Conversion to conventional therapy and perioperative triple drug have been associated with high rates of acute rejection episodes, infections, or neoplasms. We report our experience in d...

journal_title：Transplantation

authors： Pascual J,Marcén R,Orofino L,Quereda C,Mampaso F,Liaño F,Ortuño J

更新日期：1991-08-01 00:00:00

abstract：:By using the lysostrip and the blocking of cytotoxicity by Fab2 fragments, HLA-A and B antibodies were detected in sera from rabbits and goats immunized with human high-density lipoprotein (HDL)-associated HLA antigens isolated from sera and from cultured lymphoid cells. After appropriate absorptions, the xenoantisera...

journal_title：Transplantation

authors： Richiardi P,Pellegrino MA,Ferrone S

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:Liver transplantation using ABO-incompatible grafts is rarely performed because the reported outcome is poorer than with compatible grafts. We report our positive experience with adult-to-adult living-donor liver transplant (LDLT) using ABO-incompatible grafts. METHODS:The immunosuppressive protocol consist...

journal_title：Transplantation

authors： Testa G,Vidanovic V,Chejfec G,Gangemi A,Iqpal R,Porubsky M,Pham T,Benedetti E

更新日期：2008-03-15 00:00:00

abstract：BACKGROUND:Bone complications after hematopoietic stem-cell transplantation (HSCT) are relatively frequent. Evaluation of biomarkers of bone turnover and dual energy x-ray absorptiometry (DEXA) are not known in this context. METHODS:We prospectively evaluated bone mineral density, biomarkers of bone turnover, and the ...

journal_title：Transplantation

authors： Petropoulou AD,Porcher R,Herr AL,Devergie A,Brentano TF,Ribaud P,Pinto FO,Rocha V,Peffault de Latour R,Orcel P,Socié G,Robin M

更新日期：2010-06-15 00:00:00

abstract：:FK506, an immunosuppresant, was isolated from Streptomyces tsukubaensis. Intramuscular administration of FK506 (0.32 mg/kg or more) 5 days a week for two weeks after grafting prolonged the acceptance time of F344 skin allograft to WKA rats. Similar results were obtained with cyclosporine at 32 mg/kg or more, but other...

journal_title：Transplantation

authors： Inamura N,Nakahara K,Kino T,Goto T,Aoki H,Yamaguchi I,Kohsaka M,Ochiai T

更新日期：1988-01-01 00:00:00

abstract：:Kidney transplantation in elderly patients is a good therapeutic option, but the incidence of infections compared to younger patients must be studied. Case and control study was performed with 40 cases (patients older than 65) and 40 controls (younger than 65) receiving a kidney transplant between January 2000 and Aug...

journal_title：Transplantation

authors： Trouillhet I,Benito N,Cervera C,Rivas P,Cofán F,Almela M,Angeles Marcos M,Puig de la Bellacasa J,Pumarola T,Oppenheimer F,Moreno-Camacho A

更新日期：2005-10-15 00:00:00

abstract：:Survival times of allogeneic fetal pancreases were determined across various immunogenetic barriers using several inbred rat strains. Pancreases from 17-day-old embryos transplanted beneath the kidney capsule of normal, nonimmunosuppressed recipients were richly vascularized within a short period regardless of histoin...

journal_title：Transplantation

authors： Mullen Y,Shintaku IP

更新日期：1980-01-01 00:00:00

abstract：:Although the requirements for the induction of IL-2 receptor expression following lymphocyte stimulation in vitro have been well characterized, little information is available on the role of IL-2 and the IL-2 receptor in lymphocyte activation in vivo. We have established a quantitative assay for the measurement of IL-...

journal_title：Transplantation

authors： Kroczek RA,Black CD,Barbet J,Edison LJ,Shevach EM

更新日期：1987-10-01 00:00:00

abstract：:We performed a multicenter study to investigate the problem of cadaver kidney transplants that never achieve function, or that recover after a period of delayed function, and we used multivariate techniques to model the results. Sixty-nine patients who received cadaver kidney transplants that never functioned (NF) wer...

journal_title：Transplantation

authors： Halloran P,Aprile M

更新日期：1988-01-01 00:00:00

abstract：:Graft-versus-host disease (GVHD) is a common complication of bone marrow transplantation and often involves the gastrointestinal system. It is unclear whether there can be severe enough damage by GVHD to permanently injure the bowel and thereby prevent mucosal regeneration. We describe a patient who had successful tre...

journal_title：Transplantation

authors： Fox RJ,Vogelsang GB,Beschorner WE

更新日期：1996-12-15 00:00:00

abstract：BACKGROUND:This study aimed at investigating the efficacy of the novel immunosuppressant FK778 to prevent the development and progression of chronic allograft vasculopathy (CAV). METHODS:Orthotopic aortic transplantations were performed in the PVG-to-ACI rat model and followed over the course of 120 days. Immunosuppre...

journal_title：Transplantation

authors： Deuse T,Hoyt G,Koyanagi T,Robbins RC,Schrepfer S

更新日期：2008-03-27 00:00:00

abstract：:The optimal timing of administration of free radical scavengers in lung preservation has yet to be determined. In previous studies, the oxygen free radical scavenger dimethylthiourea (DMTU) has improved pulmonary function when added to Eurocollins flush solution at the time of lung harvest and infused at the time of l...

journal_title：Transplantation

authors： Lambert CJ Jr,Egan TM

更新日期：1992-08-01 00:00:00

abstract：:The length of time after syngeneic bone marrow reconstitution when tolerance to alloantigens can be induced in adult mice during T cell differentiation from bone marrow cells was studied by exposing those T cells to (recipient x donor)F1 spleen cells. Supralethally irradiated C3H/He Slc(C3H; H-2k) mice were reconstitu...

journal_title：Transplantation

authors： Tomita Y,Himeno K,Mayumi H,Tokuda N,Nomoto K

更新日期：1989-06-01 00:00:00

abstract：:Enhancement of skin grafts in mice by passively administered alloantiserum was examined in conjunction with the simultaneous use of other immunosuppressive regimens. It could be clearly shown that when a "weak" antilymphocyte serum (ALS) was used, a significant further prolongation of graft survival occurred over that...

journal_title：Transplantation

authors： Koene RA,Gerlag PG,McKenzie IF,Hagemann JF,Wijdeveld PG

更新日期：1975-09-01 00:00:00

abstract：:Mandatory continuous monitoring of early transplant outcome with centralized oversight was introduced in 2004 for all 23 UK adult kidney transplant units. Risk-adjusted cumulative sum charts are used to assess 30-day graft and patient survival against past performance for each center, and change in transplant center p...

journal_title：Transplantation

authors： Collett D,Sibanda N,Pioli S,Bradley JA,Rudge C

更新日期：2009-10-27 00:00:00

abstract：BACKGROUND:Xenogeneic corneal fragments (guinea pig) are highly resistant to immune rejection in the anterior chamber of mouse eyes. Because guinea pigs and mice are discordant (i.e., mouse serum normally contains guinea pig reactive xenoantibodies), we wished to determine the extent to which xenogeneic corneal fragmen...

journal_title：Transplantation

authors： Tanaka K,Streilein JW

更新日期：2000-02-27 00:00:00

abstract：BACKGROUND:Prophylactic administration of anti-HBs intravenous immunoglobulins (IVIg) in hepatitis B infected-liver transplant patients protects against acute rejection. To explore the suitability of intravenous immunoglobulins (IVIg) as prophylaxis of acute rejection and graft-versus-host disease (GVHD) after allograf...

journal_title：Transplantation

authors： Tha-In T,Metselaar HJ,Tilanus HW,Boor PP,Mancham S,Kuipers EJ,de Man RA,Kwekkeboom J

更新日期：2006-06-27 00:00:00

abstract：:The development of erythrocytosis following renal transplantation has been reported to be caused by a number of factors. These include acute and chronic rejection, hydronephrosis and renal artery stenosis. In this study, seven patients were noted to have erythrocytosis with hematocrits ranging between 53.5 and 66%. Se...

journal_title：Transplantation

authors： Dagher FJ,Ramos E,Erslev AJ,Alongi SV,Karmi SA,Caro J

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:Histologic evaluation of small bowel allograft biopsies is important for the diagnosis of acute rejection. However, a standard histologic schema to grade the severity of intestinal acute rejection is not currently available. The primary goal of this study was to develop a histologic grading system for the di...

journal_title：Transplantation

authors： Wu T,Abu-Elmagd K,Bond G,Nalesnik MA,Randhawa P,Demetris AJ

更新日期：2003-04-27 00:00:00

abstract：BACKGROUND:The timing of an acute rejection may have a variable impact on renal allograft survival. To determine whether the time of first acute transplant rejection (ATR) is an independent predictor of long-term allograft survival, we studied 31,600 first cadaveric renal transplants that were functional on the first t...

journal_title：Transplantation

authors： Leggat JE Jr,Ojo AO,Leichtman AB,Port FK,Wolfe RA,Turenne MN,Held PJ

更新日期：1997-05-15 00:00:00

abstract：BACKGROUND:Impaired pretransplant performance status (PS) is associated with chronic liver disease (CLD). We studied its impact on hospital length of stay (LOS), complications and readmissions in the first year after liver transplantation. METHOD:The Standard National Liver Transplant Registry was linked to a hospital...

journal_title：Transplantation

authors： Wallace D,Cowling TE,Walker K,Suddle A,Gimson A,Rowe I,Callaghan C,Heaton N,van der Meulen J,Bernal W

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:Connective tissue growth factor (CTGF) is a key mediator of tissue fibrogenesis in kidney disease. Its involvement in renal allograft fibrosis was recently demonstrated in a mouse model. METHODS:We prospectively studied the association between urinary CTGF (CTGFu) levels and renal allograft fibrosis during ...

journal_title：Transplantation

authors： Metalidis C,van Vuuren SH,Broekhuizen R,Lerut E,Naesens M,Bakker SJ,Wetzels JF,Goldschmeding R,Kuypers DR

更新日期：2013-09-15 00:00:00

abstract：BACKGROUND:The role of changes in peri-operative blood lactate levels in recipients of living-related liver transplants has not yet been clarified. METHODS:Forty-three recipients were included in this study. Blood lactate, plasma total bilirubin, aminotransferase, body temperature, and gastric mucosal PCO2 levels were...

journal_title：Transplantation

authors： Orii R,Sugawara Y,Hayashida M,Yamada Y,Kubota K,Takayama T,Harihara Y,Makuuchi M,Hanaoka K

更新日期：2000-05-27 00:00:00

abstract：BACKGROUND:Guillain-Barre Syndrome (GBS) is believed to be caused by autoimmune mechanisms that are predominantly T-cell mediated. We report GBS in organ transplant patients and bone marrow transplant patients, both of whom have iatrogenically suppressed T-cell function. METHODS:We reviewed the Duke University Medical...

journal_title：Transplantation

authors： Bulsara KR,Baron PW,Tuttle-Newhall JE,Clavien PA,Morgenlander J

更新日期：2001-04-27 00:00:00

abstract：BACKGROUND:Steroid-resistant acute rejection is a risk factor for inferior renal allograft outcome. METHODS:From 873 kidney transplant recipients (1995-2005), 108 patients with a first rejection episode were selected for study using strict inclusion criteria and clinical endpoint definition. We aimed to predict respon...

journal_title：Transplantation

authors： Rekers NV,Bajema IM,Mallat MJ,Zuidwijk K,Anholts JD,Goemaere N,Haasnoot GW,van Groningen MC,van Kooten C,de Fijter JW,Claas FH,Eikmans M

更新日期：2012-09-27 00:00:00