BCG Moreau Rio de Janeiro: an oral vaccine against tuberculosis--review.

abstract：:We present herein an improved assay for detecting the presence of extracellular proteases from microorganisms on agar plates. Using different substrates (gelatin, BSA, hemoglobin) incorporated into the agar and varying the culture medium composition, we were able to detect proteolytic activities from Pseudomonas aerug...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Vermelho AB,Meirelles MN,Lopes A,Petinate SD,Chaia AA,Branquinha MH

更新日期：1996-11-01 00:00:00

abstract：:Metalloproteinases are abundant enzymes in crotaline and viperine snake venoms. They are relevant in the pathophysiology of envenomation, being responsible for local and systemic hemorrhage frequently observed in the victims. Snake venom metalloproteinases (SVMP) are zinc-dependent enzymes of varying molecular weights...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Teixeira Cde F,Fernandes CM,Zuliani JP,Zamuner SF

更新日期：2005-03-01 00:00:00

abstract：:Nitroarylidenemalononitriles and their cyanoacetamide derivatives with remarkable anti-epimastigote properties, were synthesized attempting to obtain new 3,5-diamino-4-(5'-nitroarylidene)-4H-thiadiazine 1,1-dioxide derivatives, which in previous reports had shown anti-Trypanosoma cruzi activity. Tests to evaluate the ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Muelas-Serrano S,Le-Senne A,Fernandez-Portillo C,Nogal JJ,Ochoa C,Gomez-Barrio A

更新日期：2002-06-01 00:00:00

abstract：:A survey was conducted in a blood donor population of Central Brazil aiming to investigate the prevalence of GB virus C (GBV-C)/hepatitis G virus (HGV) infection and also to analyze the virus genotypes distribution. A total of 241 voluntary blood donors were interviewed at the State Blood Bank in Goiânia, State of Goi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Oliveira LA,Martins RM,Carneiro MA,Teles SA,Silva SA,Cardoso DD,Lampe E,Yoshida CF

更新日期：2002-10-01 00:00:00

abstract：:The influence of altitude and latitude on some structure sizes of Lutzomyia intermedia was noted; several structures of insects collected in higher localities were greater, according to Bergmann's rule. This influence was more remarkable in two localities of the State of Espírito Santo, probably due to greater differe...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Marcondes CB,Lozovei AL,Falqueto A,Brazil RP,Galati E,Aguiar G,Souza N

更新日期：1999-09-01 00:00:00

abstract：:To compare the epidemiological profile and socioeconomic factors associated to the infection by Schistosoma mansoni in a rural and an urban endemic area a cross-sectional study was performed in Agua Branca de Minas (rural area) and Bela Fama (urban area), both situated in the State of Minas Gerais, Brazil. Two hundred...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Amorim MN,Rabello A,Contreras RL,Katz N

更新日期：1997-09-01 00:00:00

abstract：:Trypanosoma cruzi acute infections often go unperceived, but one third of chronically infected individuals die of Chagas disease, showing diverse manifestations affecting the heart, intestines, and nervous systems. A common denominator of pathology in Chagas disease is the minimal rejection unit, whereby parasite-free...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Teixeira AR,Nascimento RJ,Sturm NR

更新日期：2006-08-01 00:00:00

abstract：:The presence of tRNA array, a region with high tRNA gene number and density, has been demonstrated in Mycobacterium genus. However, a recent phylogenomic study revealed the existence of five distinct monophyletic groups (genera) within this genus. Considering this new scenario, and based on in-silico analyses, we have...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Morgado SM,Vicente ACP

更新日期：2019-01-01 00:00:00

abstract：:Molecular evidence showed 46.2% of Trypanosoma cruzi infection in Mepraia spinolai insects from North-Central Chile, which is significantly higher than previous reports of up to 26% by microscopic observation. Our results show similar infection levels among nymphal stages, ranging from 38.3 to 54.1%, indicating that y...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Botto-Mahan C,Ortiz S,Rozas M,Cattan PE,Solari A

更新日期：2005-05-01 00:00:00

abstract：:Sixty eight patients with localized cutaneous leishmaniasis from an area with Leishmania (Viannia) braziliensis transmission had cultures performed with a modified Marzochís vacuum aspiratory puncture technique to establish sensitivity and contamination rate with this new method. Overall sensitivity of three aspirates...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Romero GA,Sampaio RN,Macedo Vde O,Marsden PD

更新日期：1999-07-01 00:00:00

abstract：:The objective of this work was to characterize, and compare different morphological types of hemocytes of Rhodnius prolixus, Rhodnius robustus, Rhodnius neglectus, Triatoma infestans, Panstrongylus megistus, and Dipetalogaster maximus. This information provides the basis for studying the cellular immune systems of the...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Azambuja P,Garcia ES,Ratcliffe NA

更新日期：1991-01-01 00:00:00

abstract：:Two essential oils of Lippia alba (Mill.) N.E. Brown (Verbenacea), the carvone and citral chemotypes and 15 of their compounds were evaluated to determine cytotoxicity and antifungal activity. Cytotoxicity assays for both the citral and carvone chemotypes were carried out with tetrazolium-dye, which showed a dose-depe...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mesa-Arango AC,Montiel-Ramos J,Zapata B,Durán C,Betancur-Galvis L,Stashenko E

更新日期：2009-09-01 00:00:00

abstract：:In this study, HIV-1 viral blood quantitation determined by Nucleic Acid Sequence Based Amplification (NASBA) was compared with other surrogate disease progression markers (antigen p24, CD4/CD8 cell counts and beta-2 microglobulin) in 540 patients followed up at São Paulo, SP, Brazil. HIV-1 RNA detection was statistic...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sitnik R,Pinho JR

更新日期：1998-05-01 00:00:00

abstract：:The present study investigated the diagnostic value of polymerase chain reaction (PCR) performed in parallel to conventional methods at an American tegumentary leishmaniasis (ATL) referral centre for diagnosis. Accuracy parameters for PCR were calculated using 130 patients with confirmed ATL (ATL group), 15 patients e...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Fagundes A,Schubach A,Paula CC,Bogio A,Antonio Lde F,Schiavoni PB,Monteiro Vde S,Madeira Mde F,Quintella LP,Valete-Rosalino CM,Vasconcellos Ede C,Azeredo-Coutinho RB,Pacheco RS,Marzochi MC,Marzochi KB

更新日期：2010-02-01 00:00:00

abstract：:Four superoxide dismutase (SOD) activities (SOD I, II, III, and IV) have been characterized in the epimastigote form of Trypanosoma cruzi. The total extract was subjected to two successive ammonium sulphate additions between 35 and 85%, and the resulting fraction was purified using two continuous chromatography proces...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mateo H,Marín C,Pérez-Cordón G,Sánchez-Moreno M

更新日期：2008-05-01 00:00:00

abstract：:Respiratory failure (RF) is the main cause of hospital admission in HIV/AIDS patients. This study assessed comorbidities and laboratory parameters in HIV/AIDS inpatients with RF (N = 58) in relation to those without RF (N = 36). Tuberculosis showed a huge relative risk and platelet counts were slightly higher in HIV/A...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Gama WM,Oliveira LB,Chaves YO,Ribeiro F,Almeida TVR,Baptista BJA,Santana MF,Ferreira LC,Lacerda MVG,Nogueira PA

更新日期：2020-09-14 00:00:00

abstract：:The ultrastructure of endogenous stages of Eimeria ninakohlyakimovae was observed in epithelial cells of cecum and colon crypts from a goat experimentally infected with 2.0 x 10(5) oocysts/kg. The secondary meronts developed above the nucleus of the host cell. The nucleus first divides and merozoites then form on the ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Vieira LS,Lima JD,Ribeiro MF,Bozzi IA,Camargos ER

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Lutzomyia umbratilis, the vector for Leishmania guyanensis in northern South America, has been found naturally infected with L. guyanensis only in areas north of the Negro and Amazon rivers. While populations of this sand fly species are also found in areas south of these rivers, these populations have never...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Soares RP,Nogueira PM,Secundino NF,Marialva EF,Ríos-Velásquez CM,Pessoa FAC

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The time of progression towards AIDS can vary greatly among seropositive patients, and may be associated with host genetic variation. The NR1I2 (PXR) gene, a ligand-activated transcription factor, regulates the transcription immune pathway genes and can therefore be targets of viral replication mechanisms in...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Medeiros RM,Menti CF,Benelli JL,Matte MC,Melo MG,Almeida SE,Fiegenbaum M

更新日期：2017-04-01 00:00:00

abstract：:In a recent article in the Reader's Opinion, advantages and disadvantages of the certification processes of interrupted Chagas disease transmission (American trypanosomiasis) by native vector were discussed. Such concept, accepted by those authors for the case of endemic situations with introduced vectors, has been bu...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Salvatella R,Irabedra P,Castellanos LG

更新日期：2014-02-01 00:00:00

abstract：:Mutations in the katG gene have been identified and correlated with isoniazid (INH) resistance in Mycobacterium tuberculosis isolates. The mutation AGC-->ACC (Ser-->Thr) at katG315 has been reported to be the most frequent and is associated with transmission and multidrug resistance. Rapid detection of this mutation c...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Verza M,Maschmann Rde A,Silva MS,Dalla Costa ER,Ribeiro MO,Rosso F,Suffys PN,Tortoli E,Marcelli F,Zaha A,Rossetti ML

更新日期：2009-08-01 00:00:00

abstract：:Seasonal variation in container productivity and infestation levels by Aedes aegypti were evaluated in two areas with distinct levels of urbanization degrees in Rio de Janeiro, a slum and a suburban neighborhood. The four most productive containers can generate up to 90% of total pupae. Large and open-mouthed containe...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Maciel-de-Freitas R,Marques WA,Peres RC,Cunha SP,de Oliveira RL

更新日期：2007-06-01 00:00:00

abstract：:The schistosomicidal properties of Nigella sativa seeds were tested in vitro against Schistosoma mansoni miracidia, cercariae, and adult worms. Results indicate its strong biocidal effects against all stages of the parasite and also showed an inhibitory effect on egg-laying of adult female worms. In the present work w...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mohamed AM,Metwally NM,Mahmoud SS

更新日期：2005-04-01 00:00:00

abstract：:Penicillin tolerance among 67 strains of beta-hemolytic streptococci was examined by determining the ratio of the minimal bactericidal concentration to the minimal inhibitory concentration as 32 or greater. Tolerance was demonstrated in 15 group A strains and in 11.7, and 4 of groups B, C and G, respectively. Thereaft...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Avelino CC,Benchetrit LC

更新日期：1995-07-01 00:00:00

abstract：:A large bibliographic survey provided data on Trypanosoma cruzi serology covering the period 1948-1984. Epidemiological-demographic methods provided an estimate of 11% for the prevalence of positive serology in Brazil, by 1984. Significant temporal trends were observed for most of the Brazilian geographical regions as...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Feitosa MF,Krieger H

更新日期：1991-04-01 00:00:00

abstract：:This paper presents a list of 131 Mallophaga type specimens deposited in the Werneck Collection of Instituto Oswaldo Cruz, Rio de Janeiro, RJ, Brazil. It includes 69 holotypes, 62 allotypes, 683 paratypes, 1 syntype and 2 neoparatypes, distributed among 6 families and 35 genera. The types are listed with their respect...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cardozo-de-Almeida M,Linardi PM,Costa J

更新日期：2003-03-01 00:00:00

abstract：:Didymocystis wedli a parasite from the gills of Thunnus albacares from the coast of the State of Rio de Janeiro, is described by use of light and scanning electron microscopy. This is the first report of this species in Brazil and South America. New data are presented on the surface topography as demonstrated by scann...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Kohn A,Santos A,Baptista-Farias MF

更新日期：2001-10-01 00:00:00

abstract：:The phlebotomine sand flies Nyssomyia intermedia (Lutz & Neiva, 1912) and Nyssomyia neivai (Pinto, 1926) are very close and may be involved in the transmission of Leishmania spp. Ross, 1903 in Brazil. The biology of the first laboratory-reared generations of these species, descended from insects captured in Além Paraí...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Andrade Filho JD,Galati EA,Falcão AL

更新日期：2004-10-01 00:00:00

abstract：:A massive and homogeneous amount of amastigote-like forms was detected in the stomodeal valve (SV) and the thoracic mid-gut (TMG) of Leishmania major-infected Phlebotomus papatasi, which received a second blood meal 13 to 21 days post-infection on healthy anaesthetized hamsters. After re-feeding, the infected sand fli...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Añez N,Tang Y,Rojas A,Crisante G,Killick-Kendrick M,Killick-Kendrick R

更新日期：2003-06-01 00:00:00

abstract：:In laboratory trials an aqueous solution of Piquerol A from Piqueria trinervia, collected in several regions of Mexico, showed a molluscicide action on the adults of eight different pulmonates snails species: Fossaria (Fossaria) humilis, F. (Bakerilymnaea) sp., Pseudosuccinea columella and Stagnicola attenuata from Me...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cruz-Reyes A,Chavarin C,Campos Arias MP,Taboada J,Jimenez M

更新日期：1989-01-01 00:00:00