Prevalence of human papillomavirus type 16 variants in the Federal District, Central Brazil.

Abstract:

:We report the prevalence of human papillomavirus type 16 (HPV-16) variants in women with cervical lesions from the Federal District, Central Brazil. We analyzed 34 HPV-16 samples, identifying the sequence variations of E6 and L1 genes and correlating variant frequency with disease status. The most prevalent HPV-16 variant was the European (50%), followed by Asian-American (41.2%), African-1 (5.9%), and African-2 (2.9%). European and non-European variants appeared in equal frequencies among the cytological types of lesions - atypical squamous or glandular cells of undetermined significance, cytological alterations suggesting HPV infection, cervical intraepithelial neoplasias, squamous cell carcinoma, and adenocarcinoma.

journal_name

Mem Inst Oswaldo Cruz

authors

Cruz MR,Cerqueira DM,Cruz WB,Camara GN,Brígido MM,Silva EO,Carvalho LG,Martins CR

doi

10.1590/s0074-02762004000300007

subject

Has Abstract

pub_date

2004-05-01 00:00:00

pages

281-2

issue

3

eissn

0074-0276

issn

1678-8060

pii

S0074-02762004000300007

journal_volume

99

pub_type

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